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<title xml:lang="en">Excess mortality from influenza in a large urban population, Rome, Italy, 1956--76.</title>
<author>
<name sortKey="Ragona, G" sort="Ragona, G" uniqKey="Ragona G" first="G." last="Ragona">G. Ragona</name>
</author>
<author>
<name sortKey="Giunchi, G" sort="Giunchi, G" uniqKey="Giunchi G" first="G." last="Giunchi">G. Giunchi</name>
</author>
<author>
<name sortKey="Rocchi, G" sort="Rocchi, G" uniqKey="Rocchi G" first="G." last="Rocchi">G. Rocchi</name>
</author>
<author>
<name sortKey="Muzzi, A" sort="Muzzi, A" uniqKey="Muzzi A" first="A." last="Muzzi">A. Muzzi</name>
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<author>
<name sortKey="De Felici, A" sort="De Felici, A" uniqKey="De Felici A" first="A." last="De Felici">A. De Felici</name>
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<idno type="pmid">632565</idno>
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<date when="1978">1978</date>
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<title xml:lang="en" level="a" type="main">Excess mortality from influenza in a large urban population, Rome, Italy, 1956--76.</title>
<author>
<name sortKey="Ragona, G" sort="Ragona, G" uniqKey="Ragona G" first="G." last="Ragona">G. Ragona</name>
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<author>
<name sortKey="Giunchi, G" sort="Giunchi, G" uniqKey="Giunchi G" first="G." last="Giunchi">G. Giunchi</name>
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<author>
<name sortKey="Rocchi, G" sort="Rocchi, G" uniqKey="Rocchi G" first="G." last="Rocchi">G. Rocchi</name>
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<author>
<name sortKey="Muzzi, A" sort="Muzzi, A" uniqKey="Muzzi A" first="A." last="Muzzi">A. Muzzi</name>
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<name sortKey="De Felici, A" sort="De Felici, A" uniqKey="De Felici A" first="A." last="De Felici">A. De Felici</name>
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<title level="j">The Journal of Hygiene</title>
<idno type="ISSN">0022-1724</idno>
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<date when="1978">1978</date>
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<p>Influenza activity was studied in the Rome population from 1956 to 1976 by analysis of mortality from respiratory causes and from all causes. During cold weather months, type A influenza virus was associated, as a rule, with epidemic excess deaths at two year intervals while type B virus was prevalent twice during isolation data were also compared with epidemic excess mortality during four consecutive years. The evidence obtained indicated that influenza virus isolation alone does not represent a reliable index of epidemic influenza activity in this population. The proportion of deaths attributed to respiratory causes consistently increased in every epidemic, the most pronounced increases occurring during large epidemics. The break-down by age of deaths from respiratory causes in the course of two epidemic periods showed that the percentage distribution of deaths was essentially the same as in non-epidemic periods. This evidence indicates that the same factors influencing the age-related distribution of mortality from respiratory causes during non-epidemic periods, probably affect the fatal outcome of influenza during epidemics.</p>
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<pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
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<journal-id journal-id-type="nlm-ta">J Hyg (Lond)</journal-id>
<journal-id journal-id-type="pmc">jhyg</journal-id>
<journal-title>The Journal of Hygiene</journal-title>
<issn pub-type="ppub">0022-1724</issn>
<publisher>
<publisher-name>Cambridge University Press</publisher-name>
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<article-id pub-id-type="pmid">632565</article-id>
<article-id pub-id-type="pmc">2130001</article-id>
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<subject>Research Article</subject>
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<title-group>
<article-title>Excess mortality from influenza in a large urban population, Rome, Italy, 1956--76.</article-title>
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<contrib-group>
<contrib contrib-type="author">
<name>
<surname>Ragona</surname>
<given-names>G.</given-names>
</name>
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<contrib contrib-type="author">
<name>
<surname>Giunchi</surname>
<given-names>G.</given-names>
</name>
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<contrib contrib-type="author">
<name>
<surname>Rocchi</surname>
<given-names>G.</given-names>
</name>
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<contrib contrib-type="author">
<name>
<surname>Muzzi</surname>
<given-names>A.</given-names>
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<contrib contrib-type="author">
<name>
<surname>De Felici</surname>
<given-names>A.</given-names>
</name>
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<pub-date pub-type="ppub">
<month>4</month>
<year>1978</year>
</pub-date>
<volume>80</volume>
<issue>2</issue>
<fpage>249</fpage>
<lpage>257</lpage>
<abstract>
<p>Influenza activity was studied in the Rome population from 1956 to 1976 by analysis of mortality from respiratory causes and from all causes. During cold weather months, type A influenza virus was associated, as a rule, with epidemic excess deaths at two year intervals while type B virus was prevalent twice during isolation data were also compared with epidemic excess mortality during four consecutive years. The evidence obtained indicated that influenza virus isolation alone does not represent a reliable index of epidemic influenza activity in this population. The proportion of deaths attributed to respiratory causes consistently increased in every epidemic, the most pronounced increases occurring during large epidemics. The break-down by age of deaths from respiratory causes in the course of two epidemic periods showed that the percentage distribution of deaths was essentially the same as in non-epidemic periods. This evidence indicates that the same factors influencing the age-related distribution of mortality from respiratory causes during non-epidemic periods, probably affect the fatal outcome of influenza during epidemics.</p>
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