Links to Exploration step
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Human trials with wild-type H1N1 and recombinant H3N2-H1N1 influenza A viruses of 1977-1978.</title><author><name sortKey="Beare, A S" sort="Beare, A S" uniqKey="Beare A" first="A S" last="Beare">A S Beare</name></author><author><name sortKey="Kendal, A P" sort="Kendal, A P" uniqKey="Kendal A" first="A P" last="Kendal">A P Kendal</name></author><author><name sortKey="Cox, N J" sort="Cox, N J" uniqKey="Cox N" first="N J" last="Cox">N J Cox</name></author><author><name sortKey="Scholtissek, C" sort="Scholtissek, C" uniqKey="Scholtissek C" first="C" last="Scholtissek">C. Scholtissek</name></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">7399693</idno><idno type="pmc">551014</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC551014</idno><idno type="RBID">PMC:551014</idno><date when="1980">1980</date><idno type="wicri:Area/Pmc/Corpus">000324</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000324</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Human trials with wild-type H1N1 and recombinant H3N2-H1N1 influenza A viruses of 1977-1978.</title><author><name sortKey="Beare, A S" sort="Beare, A S" uniqKey="Beare A" first="A S" last="Beare">A S Beare</name></author><author><name sortKey="Kendal, A P" sort="Kendal, A P" uniqKey="Kendal A" first="A P" last="Kendal">A P Kendal</name></author><author><name sortKey="Cox, N J" sort="Cox, N J" uniqKey="Cox N" first="N J" last="Cox">N J Cox</name></author><author><name sortKey="Scholtissek, C" sort="Scholtissek, C" uniqKey="Scholtissek C" first="C" last="Scholtissek">C. Scholtissek</name></author></analytic><series><title level="j">Infection and Immunity</title><idno type="ISSN">0019-9567</idno><idno type="eISSN">1098-5522</idno><imprint><date when="1980">1980</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>A series of trials was conducted in which wild-type A/USSR/90/77 (H1N1) influenza A virus and a few of its antigenic variants were inoculated into volunteers. Infections readily occurred in people of all ages who had initial low antibody titers, but clinical effects were generally mild in comparison with those of the previously tested subtypes, H0N1, H1N1, H2N2, H3N2. There was, however, an inverse relationship between severity of symptoms and age of volunteers, although the incidence of virus excretion and of increase in anti-hemagglutinin was apparently not age related. Naturally occurring recombinant viruses with H3 hemagglutinin and one or more genes of A/USSR/098/77-like strains were likewise studied in volunteers. These clones also produced mild symptoms, providing evidence of an attenuating effect on H3N2 viruses by the substitution of some of its genes with the genes of an H1N1 virus.</p></div></front></TEI><pmc article-type="research-article"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<front><journal-meta><journal-id journal-id-type="nlm-ta">Infect Immun</journal-id><journal-title>Infection and Immunity</journal-title><issn pub-type="ppub">0019-9567</issn><issn pub-type="epub">1098-5522</issn></journal-meta><article-meta><article-id pub-id-type="pmid">7399693</article-id><article-id pub-id-type="pmc">551014</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title>Human trials with wild-type H1N1 and recombinant H3N2-H1N1 influenza A viruses of 1977-1978.</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Beare</surname><given-names>A S</given-names></name></contrib><contrib contrib-type="author"><name><surname>Kendal</surname><given-names>A P</given-names></name></contrib><contrib contrib-type="author"><name><surname>Cox</surname><given-names>N J</given-names></name></contrib><contrib contrib-type="author"><name><surname>Scholtissek</surname><given-names>C</given-names></name></contrib></contrib-group><pub-date pub-type="ppub"><month>6</month><year>1980</year></pub-date><volume>28</volume><issue>3</issue><fpage>753</fpage><lpage>761</lpage><abstract><p>A series of trials was conducted in which wild-type A/USSR/90/77 (H1N1) influenza A virus and a few of its antigenic variants were inoculated into volunteers. Infections readily occurred in people of all ages who had initial low antibody titers, but clinical effects were generally mild in comparison with those of the previously tested subtypes, H0N1, H1N1, H2N2, H3N2. There was, however, an inverse relationship between severity of symptoms and age of volunteers, although the incidence of virus excretion and of increase in anti-hemagglutinin was apparently not age related. Naturally occurring recombinant viruses with H3 hemagglutinin and one or more genes of A/USSR/098/77-like strains were likewise studied in volunteers. These clones also produced mild symptoms, providing evidence of an attenuating effect on H3N2 viruses by the substitution of some of its genes with the genes of an H1N1 virus.</p></abstract></article-meta></front></pmc></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/H2N2V1/Data/Pmc/Corpus
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000324 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Pmc/Corpus/biblio.hfd -nk 000324 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Sante
|area= H2N2V1
|flux= Pmc
|étape= Corpus
|type= RBID
|clé=
|texte=
}}
| This area was generated with Dilib version V0.6.33. |  |