Links to Exploration step
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Cell-mediated immune response to influenza virus infections in mice.</title><author><name sortKey="Cambridge, G" sort="Cambridge, G" uniqKey="Cambridge G" first="G" last="Cambridge">G. Cambridge</name></author><author><name sortKey="Mackenzie, J S" sort="Mackenzie, J S" uniqKey="Mackenzie J" first="J S" last="Mackenzie">J S Mackenzie</name></author><author><name sortKey="Keast, D" sort="Keast, D" uniqKey="Keast D" first="D" last="Keast">D. Keast</name></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">1248876</idno><idno type="pmc">420574</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC420574</idno><idno type="RBID">PMC:420574</idno><date when="1976">1976</date><idno type="wicri:Area/Pmc/Corpus">000311</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000311</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Cell-mediated immune response to influenza virus infections in mice.</title><author><name sortKey="Cambridge, G" sort="Cambridge, G" uniqKey="Cambridge G" first="G" last="Cambridge">G. Cambridge</name></author><author><name sortKey="Mackenzie, J S" sort="Mackenzie, J S" uniqKey="Mackenzie J" first="J S" last="Mackenzie">J S Mackenzie</name></author><author><name sortKey="Keast, D" sort="Keast, D" uniqKey="Keast D" first="D" last="Keast">D. Keast</name></author></analytic><series><title level="j">Infection and Immunity</title><idno type="ISSN">0019-9567</idno><idno type="eISSN">1098-5522</idno><imprint><date when="1976">1976</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>The local and systemic cell-mediated immune (CMI) responses to influenza virus infection in mice were examined by leukocyte migration inhibition and lymphocyte-mediated cytotoxicity tests. Mice were inoculated intranasally with 5 50% lethal doses of the A/WSN (H0N1) strain of influenza virus. Cells from the lymph nodes draining the upper and lower respiratory tract were used to measure the local response, and the spleen was the source of cells used for systemic determinations. The local response by pulmonary lymph node cells was greater and appeared earlier than was observed systemically in the spleen. The specificity of the CMI response was investigated by using a heterologous virus strain, A/Jap (H2N2), and recombinants A/Jap-NWS (H2N1) and A/NWS-Jap (H0N1), obtained from a cross between A/Jap (H2N2) and a virus, A/NWS (H0N1), with surface antigenic specificity similar to that of the inoculated virus. From the results of both tests used as correlates of CMI, it appeared that the response was specific against the hemagglutinin component of the inoculated virus. No reactivity was observed against the heterologous virus A/Jap (H2N2) nor against the recombinant A/Jap-NWS (H2N1) bearing the same neuradminidase as that of the inoculated virus.</p></div></front></TEI><pmc article-type="research-article"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<front><journal-meta><journal-id journal-id-type="nlm-ta">Infect Immun</journal-id><journal-title>Infection and Immunity</journal-title><issn pub-type="ppub">0019-9567</issn><issn pub-type="epub">1098-5522</issn></journal-meta><article-meta><article-id pub-id-type="pmid">1248876</article-id><article-id pub-id-type="pmc">420574</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title>Cell-mediated immune response to influenza virus infections in mice.</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Cambridge</surname><given-names>G</given-names></name></contrib><contrib contrib-type="author"><name><surname>Mackenzie</surname><given-names>J S</given-names></name></contrib><contrib contrib-type="author"><name><surname>Keast</surname><given-names>D</given-names></name></contrib></contrib-group><pub-date pub-type="ppub"><month>1</month><year>1976</year></pub-date><volume>13</volume><issue>1</issue><fpage>36</fpage><lpage>43</lpage><abstract><p>The local and systemic cell-mediated immune (CMI) responses to influenza virus infection in mice were examined by leukocyte migration inhibition and lymphocyte-mediated cytotoxicity tests. Mice were inoculated intranasally with 5 50% lethal doses of the A/WSN (H0N1) strain of influenza virus. Cells from the lymph nodes draining the upper and lower respiratory tract were used to measure the local response, and the spleen was the source of cells used for systemic determinations. The local response by pulmonary lymph node cells was greater and appeared earlier than was observed systemically in the spleen. The specificity of the CMI response was investigated by using a heterologous virus strain, A/Jap (H2N2), and recombinants A/Jap-NWS (H2N1) and A/NWS-Jap (H0N1), obtained from a cross between A/Jap (H2N2) and a virus, A/NWS (H0N1), with surface antigenic specificity similar to that of the inoculated virus. From the results of both tests used as correlates of CMI, it appeared that the response was specific against the hemagglutinin component of the inoculated virus. No reactivity was observed against the heterologous virus A/Jap (H2N2) nor against the recombinant A/Jap-NWS (H2N1) bearing the same neuradminidase as that of the inoculated virus.</p></abstract></article-meta></front></pmc></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/H2N2V1/Data/Pmc/Corpus
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000311 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Pmc/Corpus/biblio.hfd -nk 000311 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Sante
|area= H2N2V1
|flux= Pmc
|étape= Corpus
|type= RBID
|clé=
|texte=
}}
| This area was generated with Dilib version V0.6.33. |  |