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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Sequences in Influenza A Virus PB2 Protein That Determine Productive Infection for an Avian Influenza Virus in Mouse and Human Cell Lines</title>
<author><name sortKey="Yao, Yongxiu" sort="Yao, Yongxiu" uniqKey="Yao Y" first="Yongxiu" last="Yao">Yongxiu Yao</name>
<affiliation><nlm:aff id="N0x8d0d020.0xa178160"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Mingay, Louise J" sort="Mingay, Louise J" uniqKey="Mingay L" first="Louise J." last="Mingay">Louise J. Mingay</name>
<affiliation><nlm:aff id="N0x8d0d020.0xa178160"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Mccauley, John W" sort="Mccauley, John W" uniqKey="Mccauley J" first="John W." last="Mccauley">John W. Mccauley</name>
<affiliation><nlm:aff id="N0x8d0d020.0xa178160"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Barclay, Wendy S" sort="Barclay, Wendy S" uniqKey="Barclay W" first="Wendy S." last="Barclay">Wendy S. Barclay</name>
<affiliation><nlm:aff id="N0x8d0d020.0xa178160"></nlm:aff>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PMC</idno>
<idno type="pmid">11333926</idno>
<idno type="pmc">114950</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC114950</idno>
<idno type="RBID">PMC:114950</idno>
<idno type="doi">10.1128/JVI.75.11.5410-5415.2001</idno>
<date when="2001">2001</date>
<idno type="wicri:Area/Pmc/Corpus">000141</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000141</idno>
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<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Sequences in Influenza A Virus PB2 Protein That Determine Productive Infection for an Avian Influenza Virus in Mouse and Human Cell Lines</title>
<author><name sortKey="Yao, Yongxiu" sort="Yao, Yongxiu" uniqKey="Yao Y" first="Yongxiu" last="Yao">Yongxiu Yao</name>
<affiliation><nlm:aff id="N0x8d0d020.0xa178160"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Mingay, Louise J" sort="Mingay, Louise J" uniqKey="Mingay L" first="Louise J." last="Mingay">Louise J. Mingay</name>
<affiliation><nlm:aff id="N0x8d0d020.0xa178160"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Mccauley, John W" sort="Mccauley, John W" uniqKey="Mccauley J" first="John W." last="Mccauley">John W. Mccauley</name>
<affiliation><nlm:aff id="N0x8d0d020.0xa178160"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Barclay, Wendy S" sort="Barclay, Wendy S" uniqKey="Barclay W" first="Wendy S." last="Barclay">Wendy S. Barclay</name>
<affiliation><nlm:aff id="N0x8d0d020.0xa178160"></nlm:aff>
</affiliation>
</author>
</analytic>
<series><title level="j">Journal of Virology</title>
<idno type="ISSN">0022-538X</idno>
<idno type="eISSN">1098-5514</idno>
<imprint><date when="2001">2001</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass></textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en"><p>Reverse genetics was used to analyze the host range of two avian influenza viruses which differ in their ability to replicate in mouse and human cells in culture. Engineered viruses carrying sequences encoding amino acids 362 to 581 of PB2 from a host range variant productively infect mouse and human cells.</p>
</div>
</front>
</TEI>
<pmc article-type="research-article"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<front><journal-meta><journal-id journal-id-type="nlm-ta">J Virol</journal-id>
<journal-id journal-id-type="publisher-id">J VIROL</journal-id>
<journal-title>Journal of Virology</journal-title>
<issn pub-type="ppub">0022-538X</issn>
<issn pub-type="epub">1098-5514</issn>
<publisher><publisher-name>American Society for Microbiology</publisher-name>
</publisher>
</journal-meta>
<article-meta><article-id pub-id-type="pmid">11333926</article-id>
<article-id pub-id-type="pmc">114950</article-id>
<article-id pub-id-type="publisher-id">1990</article-id>
<article-id pub-id-type="doi">10.1128/JVI.75.11.5410-5415.2001</article-id>
<article-categories><subj-group subj-group-type="heading"><subject>Virus-Cell Interactions</subject>
</subj-group>
<series-title>Note</series-title>
</article-categories>
<title-group><article-title>Sequences in Influenza A Virus PB2 Protein That Determine Productive Infection for an Avian Influenza Virus in Mouse and Human Cell Lines</article-title>
</title-group>
<contrib-group><contrib contrib-type="author"><name><surname>Yao</surname>
<given-names>Yongxiu</given-names>
</name>
<xref ref-type="aff" rid="N0x8d0d020.0xa178160">1</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Mingay</surname>
<given-names>Louise J.</given-names>
</name>
<xref ref-type="aff" rid="N0x8d0d020.0xa178160">2</xref>
</contrib>
<contrib contrib-type="author"><name><surname>McCauley</surname>
<given-names>John W.</given-names>
</name>
<xref ref-type="aff" rid="N0x8d0d020.0xa178160">3</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Barclay</surname>
<given-names>Wendy S.</given-names>
</name>
<xref ref-type="aff" rid="N0x8d0d020.0xa178160">1</xref>
<xref ref-type="author-notes" rid="FN150">*</xref>
</contrib>
</contrib-group>
<aff id="N0x8d0d020.0xa178160"> School of Animal and Microbial Sciences, University of Reading, Reading, Berkshire RG6 6AJ,<sup>1</sup>
Sir William Dunn School of Pathology, University of Oxford, Oxford OX1 3RE,<sup>2</sup>
and Institute for Animal Health, Compton Laboratory, Compton, Newbury, Berkshire RG20 7NN,<sup>3</sup>
United Kingdom</aff>
<author-notes><fn id="FN150"><label>*</label>
<p>Corresponding author. Mailing address: School of Animal and Microbial Sciences, University of Reading, P.O. Box 228, Reading, Berkshire RG6 6AJ, United Kingdom. Phone: 44-1189-316368. Fax: 44-1189-316671. E-mail: <email>w.s.barclay@reading.ac.uk</email>
.</p>
</fn>
</author-notes>
<pub-date pub-type="ppub"><month>6</month>
<year>2001</year>
</pub-date>
<volume>75</volume>
<issue>11</issue>
<fpage>5410</fpage>
<lpage>5415</lpage>
<history><date date-type="received"><day>23</day>
<month>10</month>
<year>2000</year>
</date>
<date date-type="accepted"><day>20</day>
<month>2</month>
<year>2001</year>
</date>
</history>
<copyright-statement>Copyright © 2001, American Society for Microbiology</copyright-statement>
<copyright-year>2001</copyright-year>
<abstract><p>Reverse genetics was used to analyze the host range of two avian influenza viruses which differ in their ability to replicate in mouse and human cells in culture. Engineered viruses carrying sequences encoding amino acids 362 to 581 of PB2 from a host range variant productively infect mouse and human cells.</p>
</abstract>
</article-meta>
</front>
</pmc>
</record>
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