Influenza Pandemics of the 20th Century
Identifieur interne : 000B99 ( Pmc/Checkpoint ); précédent : 000B98; suivant : 000C00Influenza Pandemics of the 20th Century
Auteurs : Edwin D. Kilbourne [États-Unis]Source :
- Emerging Infectious Diseases [ 1080-6040 ] ; 2006.
Abstract
Influenza A virus infection created confusion in distinguishing true pandemics, pseudopandemics, and epidemics.
Url:
DOI: 10.3201/eid1201.051254
PubMed: 16494710
PubMed Central: 3291411
Affiliations:
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<front><journal-meta><journal-id journal-id-type="nlm-ta">Emerg Infect Dis</journal-id><journal-id journal-id-type="publisher-id">EID</journal-id><journal-title-group><journal-title>Emerging Infectious Diseases</journal-title></journal-title-group><issn pub-type="ppub">1080-6040</issn><issn pub-type="epub">1080-6059</issn><publisher><publisher-name>Centers for Disease Control and Prevention</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">16494710</article-id><article-id pub-id-type="pmc">3291411</article-id><article-id pub-id-type="publisher-id">05-1254</article-id><article-id pub-id-type="doi">10.3201/eid1201.051254</article-id><article-categories><subj-group subj-group-type="heading"><subject>Perspective</subject></subj-group><subj-group subj-group-type="article-type"><subject>Perspective</subject></subj-group></article-categories><title-group><article-title>Influenza Pandemics of the 20th Century</article-title><alt-title alt-title-type="running-head">Influenza Pandemics of the 20th Century</alt-title></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name><surname>Kilbourne</surname><given-names>Edwin D.</given-names></name><xref ref-type="aff" rid="aff1">*</xref></contrib><aff id="aff1"><label>*</label>New York Medical College, Valhalla, New York, USA</aff></contrib-group><author-notes><corresp id="cor1">Address for correspondence: Edwin D. Kilbourne, 23 Willard Ave, Madison, CT 06443, USA; fax: 203-318-0036; email: <email xlink:href="ekilbourne@snet.net">ekilbourne@snet.net</email></corresp></author-notes><pub-date pub-type="ppub"><month>1</month><year>2006</year></pub-date><volume>12</volume><issue>1</issue><fpage>9</fpage><lpage>14</lpage><abstract abstract-type="toc"><p>Influenza A virus infection created confusion in distinguishing true pandemics, pseudopandemics, and epidemics.</p></abstract><abstract><p>Three worldwide (pandemic) outbreaks of influenza occurred in the 20th century: in 1918, 1957, and 1968. The latter 2 were in the era of modern virology and most thoroughly characterized. All 3 have been informally identified by their presumed sites of origin as Spanish, Asian, and Hong Kong influenza, respectively. They are now known to represent 3 different antigenic subtypes of influenza A virus: H1N1, H2N2, and H3N2, respectively. Not classified as true pandemics are 3 notable epidemics: a pseudopandemic in 1947 with low death rates, an epidemic in 1977 that was a pandemic in children, and an abortive epidemic of swine influenza in 1976 that was feared to have pandemic potential. Major influenza epidemics show no predictable periodicity or pattern, and all differ from one another. Evidence suggests that true pandemics with changes in hemagglutinin subtypes arise from genetic reassortment with animal influenza A viruses.</p></abstract><kwd-group kwd-group-type="author"><title>Keywords: </title><kwd>Influenza</kwd><kwd>pandemic</kwd><kwd>epidemiology</kwd><kwd>vaccine</kwd><kwd>recombination</kwd><kwd>disease</kwd><kwd>mortality</kwd><kwd>pneumonia</kwd><kwd>perspective</kwd></kwd-group></article-meta></front></pmc><affiliations><list><country><li>États-Unis</li></country><region><li>État de New York</li></region></list><tree><country name="États-Unis"><region name="État de New York"><name sortKey="Kilbourne, Edwin D" sort="Kilbourne, Edwin D" uniqKey="Kilbourne E" first="Edwin D." last="Kilbourne">Edwin D. Kilbourne</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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