Lymphocyte to monocyte ratio as a screening tool for influenza
Identifieur interne : 000924 ( Pmc/Checkpoint ); précédent : 000923; suivant : 000925Lymphocyte to monocyte ratio as a screening tool for influenza
Auteurs : George Merekoulias ; Evangelos C. Alexopoulos ; Theodore Belezos ; Eugenia Panagiotopoulou ; Dr. Med. Eleni JelastopuluSource :
- PLoS Currents [ 2157-3999 ] ; 2010.
Abstract
In fall 2009 the emergency department of a clinic in Greece with increased patient visits due to influenza-like illness observed a particular pattern in the complete blood count (CBC) of these patients. In 90% of all patients with probable influenza, lymphopenia and/or monocytosis were present. Relative lymphopenia with or without monocytosis appears to be a laboratory marker for H1N1 virus infection, a finding that could play a major role in early identifying and treating patients with new influenza A. A ratio of lymphocytes to monocytes below 2 is proposed as a screening tool for influenza infection instead of rapid tests.
Url:
DOI: 10.1371/currents.RRN1154
PubMed: 20383263
PubMed Central: 2847387
Affiliations:
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<front><journal-meta><journal-id journal-id-type="nlm-ta">PLoS Curr</journal-id><journal-id journal-id-type="iso-abbrev">PLoS Curr</journal-id><journal-title-group><journal-title>PLoS Currents</journal-title></journal-title-group><issn pub-type="epub">2157-3999</issn><publisher><publisher-name>Public Library of Science</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">20383263</article-id><article-id pub-id-type="pmc">2847387</article-id><article-id pub-id-type="publisher-id">http://knol.google.com/k/-/-/wwim31ohhvdl/1</article-id><article-id pub-id-type="doi">10.1371/currents.RRN1154</article-id><article-categories><subj-group subj-group-type="heading"><subject>Influenza</subject></subj-group></article-categories><title-group><article-title>Lymphocyte to monocyte ratio as a screening tool for influenza</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Merekoulias</surname><given-names>George</given-names></name></contrib><contrib contrib-type="author"><name><surname>Alexopoulos</surname><given-names>Evangelos C</given-names></name></contrib><contrib contrib-type="author"><name><surname>Belezos</surname><given-names>Theodore</given-names></name></contrib><contrib contrib-type="author"><name><surname>Panagiotopoulou</surname><given-names>Eugenia</given-names></name></contrib><contrib contrib-type="author"><name><surname>Jelastopulu</surname><given-names>Dr. med. Eleni</given-names></name></contrib></contrib-group><aff><sup>*</sup>University of Patras, Public health department;<sup>†</sup>University of patras, Public health department;<sup>‡</sup>ED Olympion Hospital;<sup>§</sup>University of Patras and<sup>¶</sup>Department of Public Health, School of Medicine, University of Patras</aff><pub-date pub-type="epub"><day>29</day><month>3</month><year>2010</year></pub-date><volume>2</volume><elocation-id>RRN1154</elocation-id><history><date date-type="created"><day>18</day><month>3</month><year>2010</year></date><date date-type="accepted"><day>30</day><month>3</month><year>2010</year></date></history><permissions><license xlink:href="http://creativecommons.org/licenses/by/4.0/"><license-p>This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.</license-p></license></permissions><abstract><p id="p1">In fall 2009 the emergency department of a clinic in Greece with increased patient visits due to influenza-like illness observed a particular pattern in the complete blood count (CBC) of these patients. In 90% of all patients with probable influenza, lymphopenia and/or monocytosis were present. Relative lymphopenia with or without monocytosis appears to be a laboratory marker for H1N1 virus infection, a finding that could play a major role in early identifying and treating patients with new influenza A. A ratio of lymphocytes to monocytes below 2 is proposed as a screening tool for influenza infection instead of rapid tests.</p></abstract></article-meta></front></pmc><affiliations><list></list><tree><noCountry><name sortKey="Alexopoulos, Evangelos C" sort="Alexopoulos, Evangelos C" uniqKey="Alexopoulos E" first="Evangelos C" last="Alexopoulos">Evangelos C. Alexopoulos</name><name sortKey="Belezos, Theodore" sort="Belezos, Theodore" uniqKey="Belezos T" first="Theodore" last="Belezos">Theodore Belezos</name><name sortKey="Jelastopulu, Dr Med Eleni" sort="Jelastopulu, Dr Med Eleni" uniqKey="Jelastopulu D" first="Dr. Med. Eleni" last="Jelastopulu">Dr. Med. Eleni Jelastopulu</name><name sortKey="Merekoulias, George" sort="Merekoulias, George" uniqKey="Merekoulias G" first="George" last="Merekoulias">George Merekoulias</name><name sortKey="Panagiotopoulou, Eugenia" sort="Panagiotopoulou, Eugenia" uniqKey="Panagiotopoulou E" first="Eugenia" last="Panagiotopoulou">Eugenia Panagiotopoulou</name></noCountry></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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