Neurotropic virus infections as the cause of immediate and delayed neuropathology
Identifieur interne : 000382 ( Pmc/Checkpoint ); précédent : 000381; suivant : 000383Neurotropic virus infections as the cause of immediate and delayed neuropathology
Auteurs : Martin Ludlow [Allemagne] ; Jeroen Kortekaas [Pays-Bas] ; Christiane Herden [Allemagne] ; Bernd Hoffmann [Allemagne] ; Dennis Tappe [Allemagne] ; Corinna Trebst [Allemagne] ; Diane E. Griffin [États-Unis] ; Hannah E. Brindle [Royaume-Uni] ; Tom Solomon [Royaume-Uni] ; Alan S. Brown [États-Unis] ; Debby Van Riel [Pays-Bas] ; Katja C. Wolthers [Pays-Bas] ; Dasja Pajkrt [Pays-Bas] ; Peter Wohlsein [Allemagne] ; Byron E. E. Martina [Pays-Bas] ; Wolfgang Baumg Rtner [Allemagne] ; Georges M. Verjans [Allemagne, Pays-Bas] ; Albert D. M. E. Osterhaus [Allemagne, Pays-Bas]Source :
- Acta Neuropathologica [ 0001-6322 ] ; 2015.
Abstract
A wide range of viruses from different virus families in different geographical areas, may cause immediate or delayed neuropathological changes and neurological manifestations in humans and animals. Infection by neurotropic viruses as well as the resulting immune response can irreversibly disrupt the complex structural and functional architecture of the central nervous system, frequently leaving the patient or affected animal with a poor or fatal prognosis. Mechanisms that govern neuropathogenesis and immunopathogenesis of viral infections are highlighted, using examples of well-studied virus infections that are associated with these alterations in different populations throughout the world. A better understanding of the molecular, epidemiological and biological characteristics of these infections and in particular of mechanisms that underlie their clinical manifestations may be expected to provide tools for the development of more effective intervention strategies and treatment regimens.
The online version of this article (doi:10.1007/s00401-015-1511-3) contains supplementary material, which is available to authorized users.
Url:
DOI: 10.1007/s00401-015-1511-3
PubMed: 26659576
PubMed Central: 4713712
Affiliations:
- Allemagne, Pays-Bas, Royaume-Uni, États-Unis
- Basse-Saxe, Hambourg, Hollande-Méridionale, Hollande-Septentrionale, Maryland, Utrecht (province), État de New York
- Amsterdam, Hambourg, Hanovre, Rotterdam, Utrecht
Links toward previous steps (curation, corpus...)
Links to Exploration step
PMC:4713712Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Neurotropic virus infections as the cause of immediate and delayed neuropathology</title><author><name sortKey="Ludlow, Martin" sort="Ludlow, Martin" uniqKey="Ludlow M" first="Martin" last="Ludlow">Martin Ludlow</name><affiliation wicri:level="3"><nlm:aff id="Aff1">Research Center for Emerging Infections and Zoonoses, University of Veterinary Medicine, Bünteweg 17, 30559 Hannover, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Research Center for Emerging Infections and Zoonoses, University of Veterinary Medicine, Bünteweg 17, 30559 Hannover</wicri:regionArea><placeName><region type="land" nuts="2">Basse-Saxe</region><settlement type="city">Hanovre</settlement></placeName></affiliation></author><author><name sortKey="Kortekaas, Jeroen" sort="Kortekaas, Jeroen" uniqKey="Kortekaas J" first="Jeroen" last="Kortekaas">Jeroen Kortekaas</name><affiliation wicri:level="1"><nlm:aff id="Aff2">Department of Virology, Central Veterinary Institute, Part of Wageningen University and Research Centre, Wageningen, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Virology, Central Veterinary Institute, Part of Wageningen University and Research Centre, Wageningen</wicri:regionArea><wicri:noRegion>Wageningen</wicri:noRegion></affiliation></author><author><name sortKey="Herden, Christiane" sort="Herden, Christiane" uniqKey="Herden C" first="Christiane" last="Herden">Christiane Herden</name><affiliation wicri:level="1"><nlm:aff id="Aff3">Institute of Veterinary Pathology, Justus-Liebig-University Gießen, Giessen, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Veterinary Pathology, Justus-Liebig-University Gießen, Giessen</wicri:regionArea><wicri:noRegion>Giessen</wicri:noRegion><wicri:noRegion>Giessen</wicri:noRegion><wicri:noRegion>Giessen</wicri:noRegion></affiliation></author><author><name sortKey="Hoffmann, Bernd" sort="Hoffmann, Bernd" uniqKey="Hoffmann B" first="Bernd" last="Hoffmann">Bernd Hoffmann</name><affiliation wicri:level="1"><nlm:aff id="Aff4">Institute of Diagnostic Virology, Friedrich-Loeffler-Institut, Greifswald-Insel Riems, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Diagnostic Virology, Friedrich-Loeffler-Institut, Greifswald-Insel Riems</wicri:regionArea><wicri:noRegion>Greifswald-Insel Riems</wicri:noRegion><wicri:noRegion>Greifswald-Insel Riems</wicri:noRegion><wicri:noRegion>Greifswald-Insel Riems</wicri:noRegion></affiliation></author><author><name sortKey="Tappe, Dennis" sort="Tappe, Dennis" uniqKey="Tappe D" first="Dennis" last="Tappe">Dennis Tappe</name><affiliation wicri:level="3"><nlm:aff id="Aff5">Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Bernhard Nocht Institute for Tropical Medicine, Hamburg</wicri:regionArea><placeName><settlement type="city">Hambourg</settlement><region type="land" nuts="2">Hambourg</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="Aff6">German Centre for Infection Research (DZIF), Hamburg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>German Centre for Infection Research (DZIF), Hamburg</wicri:regionArea><placeName><settlement type="city">Hambourg</settlement><region type="land" nuts="2">Hambourg</region></placeName></affiliation></author><author><name sortKey="Trebst, Corinna" sort="Trebst, Corinna" uniqKey="Trebst C" first="Corinna" last="Trebst">Corinna Trebst</name><affiliation wicri:level="3"><nlm:aff id="Aff7">Department of Neurology, Hannover Medical School, Hannover, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Neurology, Hannover Medical School, Hannover</wicri:regionArea><placeName><region type="land" nuts="2">Basse-Saxe</region><settlement type="city">Hanovre</settlement></placeName></affiliation></author><author><name sortKey="Griffin, Diane E" sort="Griffin, Diane E" uniqKey="Griffin D" first="Diane E." last="Griffin">Diane E. Griffin</name><affiliation wicri:level="2"><nlm:aff id="Aff8">W. Harry Feinstone Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD USA</nlm:aff><country>États-Unis</country><placeName><region type="state">Maryland</region></placeName><wicri:cityArea>W. Harry Feinstone Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Baltimore</wicri:cityArea></affiliation></author><author><name sortKey="Brindle, Hannah E" sort="Brindle, Hannah E" uniqKey="Brindle H" first="Hannah E." last="Brindle">Hannah E. Brindle</name><affiliation wicri:level="1"><nlm:aff id="Aff9">Institute of Infection and Global Health, University of Liverpool, Liverpool, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Institute of Infection and Global Health, University of Liverpool, Liverpool</wicri:regionArea><wicri:noRegion>Liverpool</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="Aff10">Wellcome Trust Liverpool Glasgow Centre for Global Health Research, University of Liverpool, Liverpool, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Liverpool Glasgow Centre for Global Health Research, University of Liverpool, Liverpool</wicri:regionArea><wicri:noRegion>Liverpool</wicri:noRegion></affiliation></author><author><name sortKey="Solomon, Tom" sort="Solomon, Tom" uniqKey="Solomon T" first="Tom" last="Solomon">Tom Solomon</name><affiliation wicri:level="1"><nlm:aff id="Aff9">Institute of Infection and Global Health, University of Liverpool, Liverpool, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Institute of Infection and Global Health, University of Liverpool, Liverpool</wicri:regionArea><wicri:noRegion>Liverpool</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="Aff11">NIHR Health Protection Research Unit in Emerging Infection and Zoonoses, Liverpool, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>NIHR Health Protection Research Unit in Emerging Infection and Zoonoses, Liverpool</wicri:regionArea><wicri:noRegion>Liverpool</wicri:noRegion></affiliation></author><author><name sortKey="Brown, Alan S" sort="Brown, Alan S" uniqKey="Brown A" first="Alan S." last="Brown">Alan S. Brown</name><affiliation wicri:level="2"><nlm:aff id="Aff12">Department of Psychiatry, Columbia University Medical Center, New York State Psychiatric Institute, New York, NY USA</nlm:aff><country>États-Unis</country><placeName><region type="state">État de New York</region></placeName><wicri:cityArea>Department of Psychiatry, Columbia University Medical Center, New York State Psychiatric Institute, New York</wicri:cityArea></affiliation></author><author><name sortKey="Van Riel, Debby" sort="Van Riel, Debby" uniqKey="Van Riel D" first="Debby" last="Van Riel">Debby Van Riel</name><affiliation wicri:level="3"><nlm:aff id="Aff13">Department of Viroscience, Erasmus MC, Rotterdam, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Viroscience, Erasmus MC, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Wolthers, Katja C" sort="Wolthers, Katja C" uniqKey="Wolthers K" first="Katja C." last="Wolthers">Katja C. Wolthers</name><affiliation wicri:level="3"><nlm:aff id="Aff14">Laboratory of Clinical Virology, Department of Medical Microbiology, Academic Medical Center, Amsterdam, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Laboratory of Clinical Virology, Department of Medical Microbiology, Academic Medical Center, Amsterdam</wicri:regionArea><placeName><settlement type="city">Amsterdam</settlement><region nuts="2" type="province">Hollande-Septentrionale</region></placeName></affiliation></author><author><name sortKey="Pajkrt, Dasja" sort="Pajkrt, Dasja" uniqKey="Pajkrt D" first="Dasja" last="Pajkrt">Dasja Pajkrt</name><affiliation wicri:level="3"><nlm:aff id="Aff15">Department of Pediatric Infectious Diseases, Emma Children’s Hospital, Academic Medical Center, Amsterdam, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Pediatric Infectious Diseases, Emma Children’s Hospital, Academic Medical Center, Amsterdam</wicri:regionArea><placeName><settlement type="city">Amsterdam</settlement><region nuts="2" type="province">Hollande-Septentrionale</region></placeName></affiliation></author><author><name sortKey="Wohlsein, Peter" sort="Wohlsein, Peter" uniqKey="Wohlsein P" first="Peter" last="Wohlsein">Peter Wohlsein</name><affiliation wicri:level="3"><nlm:aff id="Aff16">Department of Pathology, University of Veterinary Medicine, Hannover, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Pathology, University of Veterinary Medicine, Hannover</wicri:regionArea><placeName><region type="land" nuts="2">Basse-Saxe</region><settlement type="city">Hanovre</settlement></placeName></affiliation></author><author><name sortKey="Martina, Byron E E" sort="Martina, Byron E E" uniqKey="Martina B" first="Byron E. E." last="Martina">Byron E. E. Martina</name><affiliation wicri:level="3"><nlm:aff id="Aff13">Department of Viroscience, Erasmus MC, Rotterdam, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Viroscience, Erasmus MC, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="Aff17">Artemis One Health, Utrecht, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Artemis One Health, Utrecht</wicri:regionArea><placeName><settlement type="city">Utrecht</settlement><region nuts="2" type="province">Utrecht (province)</region></placeName></affiliation></author><author><name sortKey="Baumg Rtner, Wolfgang" sort="Baumg Rtner, Wolfgang" uniqKey="Baumg Rtner W" first="Wolfgang" last="Baumg Rtner">Wolfgang Baumg Rtner</name><affiliation wicri:level="3"><nlm:aff id="Aff16">Department of Pathology, University of Veterinary Medicine, Hannover, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Pathology, University of Veterinary Medicine, Hannover</wicri:regionArea><placeName><region type="land" nuts="2">Basse-Saxe</region><settlement type="city">Hanovre</settlement></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="Aff18">Center of Systems Neuroscience, Hannover, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Center of Systems Neuroscience, Hannover</wicri:regionArea><placeName><region type="land" nuts="2">Basse-Saxe</region><settlement type="city">Hanovre</settlement></placeName></affiliation></author><author><name sortKey="Verjans, Georges M" sort="Verjans, Georges M" uniqKey="Verjans G" first="Georges M." last="Verjans">Georges M. Verjans</name><affiliation wicri:level="3"><nlm:aff id="Aff1">Research Center for Emerging Infections and Zoonoses, University of Veterinary Medicine, Bünteweg 17, 30559 Hannover, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Research Center for Emerging Infections and Zoonoses, University of Veterinary Medicine, Bünteweg 17, 30559 Hannover</wicri:regionArea><placeName><region type="land" nuts="2">Basse-Saxe</region><settlement type="city">Hanovre</settlement></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="Aff13">Department of Viroscience, Erasmus MC, Rotterdam, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Viroscience, Erasmus MC, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Osterhaus, Albert D M E" sort="Osterhaus, Albert D M E" uniqKey="Osterhaus A" first="Albert D. M. E." last="Osterhaus">Albert D. M. E. Osterhaus</name><affiliation wicri:level="3"><nlm:aff id="Aff1">Research Center for Emerging Infections and Zoonoses, University of Veterinary Medicine, Bünteweg 17, 30559 Hannover, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Research Center for Emerging Infections and Zoonoses, University of Veterinary Medicine, Bünteweg 17, 30559 Hannover</wicri:regionArea><placeName><region type="land" nuts="2">Basse-Saxe</region><settlement type="city">Hanovre</settlement></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="Aff17">Artemis One Health, Utrecht, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Artemis One Health, Utrecht</wicri:regionArea><placeName><settlement type="city">Utrecht</settlement><region nuts="2" type="province">Utrecht (province)</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="Aff18">Center of Systems Neuroscience, Hannover, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Center of Systems Neuroscience, Hannover</wicri:regionArea><placeName><region type="land" nuts="2">Basse-Saxe</region><settlement type="city">Hanovre</settlement></placeName></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">26659576</idno><idno type="pmc">4713712</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4713712</idno><idno type="RBID">PMC:4713712</idno><idno type="doi">10.1007/s00401-015-1511-3</idno><date when="2015">2015</date><idno type="wicri:Area/Pmc/Corpus">000219</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000219</idno><idno type="wicri:Area/Pmc/Curation">000219</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000219</idno><idno type="wicri:Area/Pmc/Checkpoint">000382</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000382</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Neurotropic virus infections as the cause of immediate and delayed neuropathology</title><author><name sortKey="Ludlow, Martin" sort="Ludlow, Martin" uniqKey="Ludlow M" first="Martin" last="Ludlow">Martin Ludlow</name><affiliation wicri:level="3"><nlm:aff id="Aff1">Research Center for Emerging Infections and Zoonoses, University of Veterinary Medicine, Bünteweg 17, 30559 Hannover, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Research Center for Emerging Infections and Zoonoses, University of Veterinary Medicine, Bünteweg 17, 30559 Hannover</wicri:regionArea><placeName><region type="land" nuts="2">Basse-Saxe</region><settlement type="city">Hanovre</settlement></placeName></affiliation></author><author><name sortKey="Kortekaas, Jeroen" sort="Kortekaas, Jeroen" uniqKey="Kortekaas J" first="Jeroen" last="Kortekaas">Jeroen Kortekaas</name><affiliation wicri:level="1"><nlm:aff id="Aff2">Department of Virology, Central Veterinary Institute, Part of Wageningen University and Research Centre, Wageningen, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Virology, Central Veterinary Institute, Part of Wageningen University and Research Centre, Wageningen</wicri:regionArea><wicri:noRegion>Wageningen</wicri:noRegion></affiliation></author><author><name sortKey="Herden, Christiane" sort="Herden, Christiane" uniqKey="Herden C" first="Christiane" last="Herden">Christiane Herden</name><affiliation wicri:level="1"><nlm:aff id="Aff3">Institute of Veterinary Pathology, Justus-Liebig-University Gießen, Giessen, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Veterinary Pathology, Justus-Liebig-University Gießen, Giessen</wicri:regionArea><wicri:noRegion>Giessen</wicri:noRegion><wicri:noRegion>Giessen</wicri:noRegion><wicri:noRegion>Giessen</wicri:noRegion></affiliation></author><author><name sortKey="Hoffmann, Bernd" sort="Hoffmann, Bernd" uniqKey="Hoffmann B" first="Bernd" last="Hoffmann">Bernd Hoffmann</name><affiliation wicri:level="1"><nlm:aff id="Aff4">Institute of Diagnostic Virology, Friedrich-Loeffler-Institut, Greifswald-Insel Riems, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Diagnostic Virology, Friedrich-Loeffler-Institut, Greifswald-Insel Riems</wicri:regionArea><wicri:noRegion>Greifswald-Insel Riems</wicri:noRegion><wicri:noRegion>Greifswald-Insel Riems</wicri:noRegion><wicri:noRegion>Greifswald-Insel Riems</wicri:noRegion></affiliation></author><author><name sortKey="Tappe, Dennis" sort="Tappe, Dennis" uniqKey="Tappe D" first="Dennis" last="Tappe">Dennis Tappe</name><affiliation wicri:level="3"><nlm:aff id="Aff5">Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Bernhard Nocht Institute for Tropical Medicine, Hamburg</wicri:regionArea><placeName><settlement type="city">Hambourg</settlement><region type="land" nuts="2">Hambourg</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="Aff6">German Centre for Infection Research (DZIF), Hamburg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>German Centre for Infection Research (DZIF), Hamburg</wicri:regionArea><placeName><settlement type="city">Hambourg</settlement><region type="land" nuts="2">Hambourg</region></placeName></affiliation></author><author><name sortKey="Trebst, Corinna" sort="Trebst, Corinna" uniqKey="Trebst C" first="Corinna" last="Trebst">Corinna Trebst</name><affiliation wicri:level="3"><nlm:aff id="Aff7">Department of Neurology, Hannover Medical School, Hannover, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Neurology, Hannover Medical School, Hannover</wicri:regionArea><placeName><region type="land" nuts="2">Basse-Saxe</region><settlement type="city">Hanovre</settlement></placeName></affiliation></author><author><name sortKey="Griffin, Diane E" sort="Griffin, Diane E" uniqKey="Griffin D" first="Diane E." last="Griffin">Diane E. Griffin</name><affiliation wicri:level="2"><nlm:aff id="Aff8">W. Harry Feinstone Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD USA</nlm:aff><country>États-Unis</country><placeName><region type="state">Maryland</region></placeName><wicri:cityArea>W. Harry Feinstone Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Baltimore</wicri:cityArea></affiliation></author><author><name sortKey="Brindle, Hannah E" sort="Brindle, Hannah E" uniqKey="Brindle H" first="Hannah E." last="Brindle">Hannah E. Brindle</name><affiliation wicri:level="1"><nlm:aff id="Aff9">Institute of Infection and Global Health, University of Liverpool, Liverpool, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Institute of Infection and Global Health, University of Liverpool, Liverpool</wicri:regionArea><wicri:noRegion>Liverpool</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="Aff10">Wellcome Trust Liverpool Glasgow Centre for Global Health Research, University of Liverpool, Liverpool, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Liverpool Glasgow Centre for Global Health Research, University of Liverpool, Liverpool</wicri:regionArea><wicri:noRegion>Liverpool</wicri:noRegion></affiliation></author><author><name sortKey="Solomon, Tom" sort="Solomon, Tom" uniqKey="Solomon T" first="Tom" last="Solomon">Tom Solomon</name><affiliation wicri:level="1"><nlm:aff id="Aff9">Institute of Infection and Global Health, University of Liverpool, Liverpool, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Institute of Infection and Global Health, University of Liverpool, Liverpool</wicri:regionArea><wicri:noRegion>Liverpool</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="Aff11">NIHR Health Protection Research Unit in Emerging Infection and Zoonoses, Liverpool, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>NIHR Health Protection Research Unit in Emerging Infection and Zoonoses, Liverpool</wicri:regionArea><wicri:noRegion>Liverpool</wicri:noRegion></affiliation></author><author><name sortKey="Brown, Alan S" sort="Brown, Alan S" uniqKey="Brown A" first="Alan S." last="Brown">Alan S. Brown</name><affiliation wicri:level="2"><nlm:aff id="Aff12">Department of Psychiatry, Columbia University Medical Center, New York State Psychiatric Institute, New York, NY USA</nlm:aff><country>États-Unis</country><placeName><region type="state">État de New York</region></placeName><wicri:cityArea>Department of Psychiatry, Columbia University Medical Center, New York State Psychiatric Institute, New York</wicri:cityArea></affiliation></author><author><name sortKey="Van Riel, Debby" sort="Van Riel, Debby" uniqKey="Van Riel D" first="Debby" last="Van Riel">Debby Van Riel</name><affiliation wicri:level="3"><nlm:aff id="Aff13">Department of Viroscience, Erasmus MC, Rotterdam, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Viroscience, Erasmus MC, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Wolthers, Katja C" sort="Wolthers, Katja C" uniqKey="Wolthers K" first="Katja C." last="Wolthers">Katja C. Wolthers</name><affiliation wicri:level="3"><nlm:aff id="Aff14">Laboratory of Clinical Virology, Department of Medical Microbiology, Academic Medical Center, Amsterdam, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Laboratory of Clinical Virology, Department of Medical Microbiology, Academic Medical Center, Amsterdam</wicri:regionArea><placeName><settlement type="city">Amsterdam</settlement><region nuts="2" type="province">Hollande-Septentrionale</region></placeName></affiliation></author><author><name sortKey="Pajkrt, Dasja" sort="Pajkrt, Dasja" uniqKey="Pajkrt D" first="Dasja" last="Pajkrt">Dasja Pajkrt</name><affiliation wicri:level="3"><nlm:aff id="Aff15">Department of Pediatric Infectious Diseases, Emma Children’s Hospital, Academic Medical Center, Amsterdam, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Pediatric Infectious Diseases, Emma Children’s Hospital, Academic Medical Center, Amsterdam</wicri:regionArea><placeName><settlement type="city">Amsterdam</settlement><region nuts="2" type="province">Hollande-Septentrionale</region></placeName></affiliation></author><author><name sortKey="Wohlsein, Peter" sort="Wohlsein, Peter" uniqKey="Wohlsein P" first="Peter" last="Wohlsein">Peter Wohlsein</name><affiliation wicri:level="3"><nlm:aff id="Aff16">Department of Pathology, University of Veterinary Medicine, Hannover, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Pathology, University of Veterinary Medicine, Hannover</wicri:regionArea><placeName><region type="land" nuts="2">Basse-Saxe</region><settlement type="city">Hanovre</settlement></placeName></affiliation></author><author><name sortKey="Martina, Byron E E" sort="Martina, Byron E E" uniqKey="Martina B" first="Byron E. E." last="Martina">Byron E. E. Martina</name><affiliation wicri:level="3"><nlm:aff id="Aff13">Department of Viroscience, Erasmus MC, Rotterdam, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Viroscience, Erasmus MC, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="Aff17">Artemis One Health, Utrecht, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Artemis One Health, Utrecht</wicri:regionArea><placeName><settlement type="city">Utrecht</settlement><region nuts="2" type="province">Utrecht (province)</region></placeName></affiliation></author><author><name sortKey="Baumg Rtner, Wolfgang" sort="Baumg Rtner, Wolfgang" uniqKey="Baumg Rtner W" first="Wolfgang" last="Baumg Rtner">Wolfgang Baumg Rtner</name><affiliation wicri:level="3"><nlm:aff id="Aff16">Department of Pathology, University of Veterinary Medicine, Hannover, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Pathology, University of Veterinary Medicine, Hannover</wicri:regionArea><placeName><region type="land" nuts="2">Basse-Saxe</region><settlement type="city">Hanovre</settlement></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="Aff18">Center of Systems Neuroscience, Hannover, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Center of Systems Neuroscience, Hannover</wicri:regionArea><placeName><region type="land" nuts="2">Basse-Saxe</region><settlement type="city">Hanovre</settlement></placeName></affiliation></author><author><name sortKey="Verjans, Georges M" sort="Verjans, Georges M" uniqKey="Verjans G" first="Georges M." last="Verjans">Georges M. Verjans</name><affiliation wicri:level="3"><nlm:aff id="Aff1">Research Center for Emerging Infections and Zoonoses, University of Veterinary Medicine, Bünteweg 17, 30559 Hannover, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Research Center for Emerging Infections and Zoonoses, University of Veterinary Medicine, Bünteweg 17, 30559 Hannover</wicri:regionArea><placeName><region type="land" nuts="2">Basse-Saxe</region><settlement type="city">Hanovre</settlement></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="Aff13">Department of Viroscience, Erasmus MC, Rotterdam, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Viroscience, Erasmus MC, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Osterhaus, Albert D M E" sort="Osterhaus, Albert D M E" uniqKey="Osterhaus A" first="Albert D. M. E." last="Osterhaus">Albert D. M. E. Osterhaus</name><affiliation wicri:level="3"><nlm:aff id="Aff1">Research Center for Emerging Infections and Zoonoses, University of Veterinary Medicine, Bünteweg 17, 30559 Hannover, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Research Center for Emerging Infections and Zoonoses, University of Veterinary Medicine, Bünteweg 17, 30559 Hannover</wicri:regionArea><placeName><region type="land" nuts="2">Basse-Saxe</region><settlement type="city">Hanovre</settlement></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="Aff17">Artemis One Health, Utrecht, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Artemis One Health, Utrecht</wicri:regionArea><placeName><settlement type="city">Utrecht</settlement><region nuts="2" type="province">Utrecht (province)</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="Aff18">Center of Systems Neuroscience, Hannover, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Center of Systems Neuroscience, Hannover</wicri:regionArea><placeName><region type="land" nuts="2">Basse-Saxe</region><settlement type="city">Hanovre</settlement></placeName></affiliation></author></analytic><series><title level="j">Acta Neuropathologica</title><idno type="ISSN">0001-6322</idno><idno type="eISSN">1432-0533</idno><imprint><date when="2015">2015</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>A wide range of viruses from different virus families in different geographical areas, may cause immediate or delayed neuropathological changes and neurological manifestations in humans and animals. Infection by neurotropic viruses as well as the resulting immune response can irreversibly disrupt the complex structural and functional architecture of the central nervous system, frequently leaving the patient or affected animal with a poor or fatal prognosis. Mechanisms that govern neuropathogenesis and immunopathogenesis of viral infections are highlighted, using examples of well-studied virus infections that are associated with these alterations in different populations throughout the world. A better understanding of the molecular, epidemiological and biological characteristics of these infections and in particular of mechanisms that underlie their clinical manifestations may be expected to provide tools for the development of more effective intervention strategies and treatment regimens.</p><sec><title>Electronic supplementary material</title><p>The online version of this article (doi:10.1007/s00401-015-1511-3) contains supplementary material, which is available to authorized users.</p></sec></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Abdel Wahab, Ks" uniqKey="Abdel Wahab K">KS Abdel-Wahab</name></author><author><name sortKey="El Baz, Lm" uniqKey="El Baz L">LM El Baz</name></author><author><name sortKey="El Tayeb, Em" uniqKey="El Tayeb E">EM El-Tayeb</name></author><author><name sortKey="Omar, H" uniqKey="Omar H">H Omar</name></author><author><name sortKey="Ossman, Ma" uniqKey="Ossman M">MA Ossman</name></author><author><name sortKey="Yasin, W" uniqKey="Yasin W">W Yasin</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Abul Kasim, K" uniqKey="Abul Kasim K">K Abul-Kasim</name></author><author><name sortKey="Palm, L" uniqKey="Palm L">L Palm</name></author><author><name sortKey="Maly, P" uniqKey="Maly P">P Maly</name></author><author><name sortKey="Sundgren, Pc" uniqKey="Sundgren P">PC Sundgren</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Agamanolis, Dp" uniqKey="Agamanolis D">DP Agamanolis</name></author><author><name sortKey="Tan, Js" uniqKey="Tan J">JS Tan</name></author><author><name sortKey="Parker, Dl" uniqKey="Parker D">DL Parker</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Agut, H" uniqKey="Agut H">H Agut</name></author><author><name sortKey="Bonnafous, P" uniqKey="Bonnafous P">P Bonnafous</name></author><author><name sortKey="Gautheret Dejean, A" uniqKey="Gautheret Dejean A">A Gautheret-Dejean</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Alker, A" uniqKey="Alker A">A Alker</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Allen, Iv" uniqKey="Allen I">IV Allen</name></author><author><name sortKey="Mcquaid, S" uniqKey="Mcquaid S">S McQuaid</name></author><author><name sortKey="Mcmahon, J" uniqKey="Mcmahon J">J McMahon</name></author><author><name sortKey="Kirk, J" uniqKey="Kirk J">J Kirk</name></author><author><name sortKey="Mcconnell, R" uniqKey="Mcconnell R">R McConnell</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Allen, R" uniqKey="Allen R">R Allen</name></author><author><name sortKey="Taylor, Sk" uniqKey="Taylor S">SK Taylor</name></author><author><name sortKey="Sulkin, Se" uniqKey="Sulkin S">SE Sulkin</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Aoki, K" uniqKey="Aoki K">K Aoki</name></author><author><name sortKey="Arima, H" uniqKey="Arima H">H Arima</name></author><author><name sortKey="Kato, A" uniqKey="Kato A">A Kato</name></author><author><name sortKey="Hashimoto, H" uniqKey="Hashimoto H">H Hashimoto</name></author><author><name sortKey="Tabata, S" uniqKey="Tabata S">S Tabata</name></author><author><name sortKey="Matsushita, A" uniqKey="Matsushita A">A Matsushita</name></author><author><name sortKey="Ishikawa, T" uniqKey="Ishikawa T">T Ishikawa</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Armangue, T" uniqKey="Armangue T">T Armangue</name></author><author><name sortKey="Leypoldt, F" uniqKey="Leypoldt F">F Leypoldt</name></author><author><name sortKey="Malaga, I" uniqKey="Malaga I">I Málaga</name></author><author><name sortKey="Raspall Chaure, M" uniqKey="Raspall Chaure M">M Raspall-Chaure</name></author><author><name sortKey="Marti, I" uniqKey="Marti I">I Marti</name></author><author><name sortKey="Nichter, C" uniqKey="Nichter C">C Nichter</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Arpino, C" uniqKey="Arpino C">C Arpino</name></author><author><name sortKey="Curatolo, P" uniqKey="Curatolo P">P Curatolo</name></author><author><name sortKey="Rezza, G" uniqKey="Rezza G">G Rezza</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Baldelli, F" uniqKey="Baldelli F">F Baldelli</name></author><author><name sortKey="Ciufolini, Mg" uniqKey="Ciufolini M">MG Ciufolini</name></author><author><name sortKey="Francisci, D" uniqKey="Francisci D">D Francisci</name></author><author><name sortKey="Marchi, A" uniqKey="Marchi A">A Marchi</name></author><author><name sortKey="Venturi, G" uniqKey="Venturi G">G Venturi</name></author><author><name sortKey="Fiorentini, C" uniqKey="Fiorentini C">C Fiorentini</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Benschop, K" uniqKey="Benschop K">K Benschop</name></author><author><name sortKey="Wildenbeest, J" uniqKey="Wildenbeest J">J Wildenbeest</name></author><author><name sortKey="Pajkrt, D" uniqKey="Pajkrt D">D Pajkrt</name></author><author><name sortKey="Wolthers, K" uniqKey="Wolthers K">K Wolthers</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bissel, Sj" uniqKey="Bissel S">SJ Bissel</name></author><author><name sortKey="Auer, Rn" uniqKey="Auer R">RN Auer</name></author><author><name sortKey="Chiang, Ch" uniqKey="Chiang C">CH Chiang</name></author><author><name sortKey="Kofler, J" uniqKey="Kofler J">J Kofler</name></author><author><name sortKey="Murdoch, Gh" uniqKey="Murdoch G">GH Murdoch</name></author><author><name sortKey="Nix, Wa" uniqKey="Nix W">WA Nix</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Borgherini, G" uniqKey="Borgherini G">G Borgherini</name></author><author><name sortKey="Poubeau, P" uniqKey="Poubeau P">P Poubeau</name></author><author><name sortKey="Staikowsky, F" uniqKey="Staikowsky F">F Staikowsky</name></author><author><name sortKey="Lory, M" uniqKey="Lory M">M Lory</name></author><author><name sortKey="Le Moullec, N" uniqKey="Le Moullec N">N Le Moullec</name></author><author><name sortKey="Becquart, Jp" uniqKey="Becquart J">JP Becquart</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bourg, M" uniqKey="Bourg M">M Bourg</name></author><author><name sortKey="Herzog, S" uniqKey="Herzog S">S Herzog</name></author><author><name sortKey="Encarnacao, Ja" uniqKey="Encarnacao J">JA Encarnacao</name></author><author><name sortKey="Nobach, D" uniqKey="Nobach D">D Nobach</name></author><author><name sortKey="Lange Herbst, H" uniqKey="Lange Herbst H">H Lange-Herbst</name></author><author><name sortKey="Eickmann, M" uniqKey="Eickmann M">M Eickmann</name></author><author><name sortKey="Herden, C" uniqKey="Herden C">C Herden</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Breuer, J" uniqKey="Breuer J">J Breuer</name></author><author><name sortKey="Pacou, M" uniqKey="Pacou M">M Pacou</name></author><author><name sortKey="Gauthier, A" uniqKey="Gauthier A">A Gauthier</name></author><author><name sortKey="Brown, Mm" uniqKey="Brown M">MM Brown</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Brown, As" uniqKey="Brown A">AS Brown</name></author><author><name sortKey="Begg, Md" uniqKey="Begg M">MD Begg</name></author><author><name sortKey="Gravenstein, S" uniqKey="Gravenstein S">S Gravenstein</name></author><author><name sortKey="Schaefer, Ca" uniqKey="Schaefer C">CA Schaefer</name></author><author><name sortKey="Wyatt, Rj" uniqKey="Wyatt R">RJ Wyatt</name></author><author><name sortKey="Bresnahan, M" uniqKey="Bresnahan M">M Bresnahan</name></author><author><name sortKey="Babulas, Vp" uniqKey="Babulas V">VP Babulas</name></author><author><name sortKey="Susser, Es" uniqKey="Susser E">ES Susser</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Brown, As" uniqKey="Brown A">AS Brown</name></author><author><name sortKey="Derkits, Ej" uniqKey="Derkits E">EJ Derkits</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Canetta, Se" uniqKey="Canetta S">SE Canetta</name></author><author><name sortKey="Bao, Y" uniqKey="Bao Y">Y Bao</name></author><author><name sortKey="Co, Md" uniqKey="Co M">MD Co</name></author><author><name sortKey="Ennis, Fa" uniqKey="Ennis F">FA Ennis</name></author><author><name sortKey="Cruz, J" uniqKey="Cruz J">J Cruz</name></author><author><name sortKey="Terajima, M" uniqKey="Terajima M">M Terajima</name></author><author><name sortKey="Shen, L" uniqKey="Shen L">L Shen</name></author><author><name sortKey="Kellendonk, C" uniqKey="Kellendonk C">C Kellendonk</name></author><author><name sortKey="Schaefer, Ca" uniqKey="Schaefer C">CA Schaefer</name></author><author><name sortKey="Brown, As" uniqKey="Brown A">AS Brown</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Cerna, F" uniqKey="Cerna F">F Cerna</name></author><author><name sortKey="Mehrad, B" uniqKey="Mehrad B">B Mehrad</name></author><author><name sortKey="Luby, Jp" uniqKey="Luby J">JP Luby</name></author><author><name sortKey="Burns, D" uniqKey="Burns D">D Burns</name></author><author><name sortKey="Fleckenstein, Jl" uniqKey="Fleckenstein J">JL Fleckenstein</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Cheeran, Mcj" uniqKey="Cheeran M">MCJ Cheeran</name></author><author><name sortKey="Lokensgard, Jr" uniqKey="Lokensgard J">JR Lokensgard</name></author><author><name sortKey="Schleiss, Mr" uniqKey="Schleiss M">MR Schleiss</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Chen, Wr" uniqKey="Chen W">WR Chen</name></author><author><name sortKey="Tesh, Rb" uniqKey="Tesh R">RB Tesh</name></author><author><name sortKey="Rico Hesse, R" uniqKey="Rico Hesse R">R Rico-Hesse</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Chow, Fc" uniqKey="Chow F">FC Chow</name></author><author><name sortKey="Glaser, Ca" uniqKey="Glaser C">CA Glaser</name></author><author><name sortKey="Sheriff, H" uniqKey="Sheriff H">H Sheriff</name></author><author><name sortKey="Xia, D" uniqKey="Xia D">D Xia</name></author><author><name sortKey="Messenger, S" uniqKey="Messenger S">S Messenger</name></author><author><name sortKey="Whitley, R" uniqKey="Whitley R">R Whitley</name></author><author><name sortKey="Venkatesan, A" uniqKey="Venkatesan A">A Venkatesan</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Chowers, My" uniqKey="Chowers M">MY Chowers</name></author><author><name sortKey="Lang, R" uniqKey="Lang R">R Lang</name></author><author><name sortKey="Nassar, F" uniqKey="Nassar F">F Nassar</name></author><author><name sortKey="Ben David, D" uniqKey="Ben David D">D Ben-David</name></author><author><name sortKey="Giladi, M" uniqKey="Giladi M">M Giladi</name></author><author><name sortKey="Rubinshtein, E" uniqKey="Rubinshtein E">E Rubinshtein</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="De Jong, Md" uniqKey="De Jong M">MD de Jong</name></author><author><name sortKey="Bach, Vc" uniqKey="Bach V">VC Bach</name></author><author><name sortKey="Phan, Tq" uniqKey="Phan T">TQ Phan</name></author><author><name sortKey="Vo, Mh" uniqKey="Vo M">MH Vo</name></author><author><name sortKey="Tran, Tt" uniqKey="Tran T">TT Tran</name></author><author><name sortKey="Nguyen, Bh" uniqKey="Nguyen B">BH Nguyen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="De La Monte, S" uniqKey="De La Monte S">S de la Monte</name></author><author><name sortKey="Castro, F" uniqKey="Castro F">F Castro</name></author><author><name sortKey="Bonilla, Nj" uniqKey="Bonilla N">NJ Bonilla</name></author><author><name sortKey="Gaskin De Urdaneta, A" uniqKey="Gaskin De Urdaneta A">A Gaskin de Urdaneta</name></author><author><name sortKey="Hutchins, Gm" uniqKey="Hutchins G">GM Hutchins</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Deresiewicz, Rl" uniqKey="Deresiewicz R">RL Deresiewicz</name></author><author><name sortKey="Thaler, Sj" uniqKey="Thaler S">SJ Thaler</name></author><author><name sortKey="Hsu, L" uniqKey="Hsu L">L Hsu</name></author><author><name sortKey="Zamani, Aa" uniqKey="Zamani A">AA Zamani</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Dionisio, D" uniqKey="Dionisio D">D Dionisio</name></author><author><name sortKey="Valassina, M" uniqKey="Valassina M">M Valassina</name></author><author><name sortKey="Ciufolini, Mg" uniqKey="Ciufolini M">MG Ciufolini</name></author><author><name sortKey="Vivarelli, A" uniqKey="Vivarelli A">A Vivarelli</name></author><author><name sortKey="Esperti, F" uniqKey="Esperti F">F Esperti</name></author><author><name sortKey="Cusi, Mg" uniqKey="Cusi M">MG Cusi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Doja, A" uniqKey="Doja A">A Doja</name></author><author><name sortKey="Bitnun, A" uniqKey="Bitnun A">A Bitnun</name></author><author><name sortKey="Jones, El" uniqKey="Jones E">EL Jones</name></author><author><name sortKey="Richardson, S" uniqKey="Richardson S">S Richardson</name></author><author><name sortKey="Tellier, R" uniqKey="Tellier R">R Tellier</name></author><author><name sortKey="Petric, M" uniqKey="Petric M">M Petric</name></author><author><name sortKey="Heurter, H" uniqKey="Heurter H">H Heurter</name></author><author><name sortKey="Macgregor, D" uniqKey="Macgregor D">D Macgregor</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Donohue, Wl" uniqKey="Donohue W">WL Donohue</name></author><author><name sortKey="Playfair, Fd" uniqKey="Playfair F">FD Playfair</name></author><author><name sortKey="Whitaker, L" uniqKey="Whitaker L">L Whitaker</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Doty, Rl" uniqKey="Doty R">RL Doty</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Drexler, Jf" uniqKey="Drexler J">JF Drexler</name></author><author><name sortKey="Corman, Vm" uniqKey="Corman V">VM Corman</name></author><author><name sortKey="Muller, Ma" uniqKey="Muller M">MA Muller</name></author><author><name sortKey="Maganga, Gd" uniqKey="Maganga G">GD Maganga</name></author><author><name sortKey="Vallo, P" uniqKey="Vallo P">P Vallo</name></author><author><name sortKey="Binger, T" uniqKey="Binger T">T Binger</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Durrwald, R" uniqKey="Durrwald R">R Durrwald</name></author><author><name sortKey="Kolodziejek, J" uniqKey="Kolodziejek J">J Kolodziejek</name></author><author><name sortKey="Herzog, S" uniqKey="Herzog S">S Herzog</name></author><author><name sortKey="Nowotny, N" uniqKey="Nowotny N">N Nowotny</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Dutta, K" uniqKey="Dutta K">K Dutta</name></author><author><name sortKey="Kumawat, Kl" uniqKey="Kumawat K">KL Kumawat</name></author><author><name sortKey="Nazmi, A" uniqKey="Nazmi A">A Nazmi</name></author><author><name sortKey="Mishra, Mk" uniqKey="Mishra M">MK Mishra</name></author><author><name sortKey="Basu, A" uniqKey="Basu A">A Basu</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Eberhardt, O" uniqKey="Eberhardt O">O Eberhardt</name></author><author><name sortKey="Kuker, W" uniqKey="Kuker W">W Kuker</name></author><author><name sortKey="Dichgans, J" uniqKey="Dichgans J">J Dichgans</name></author><author><name sortKey="Weller, M" uniqKey="Weller M">M Weller</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Forest, F" uniqKey="Forest F">F Forest</name></author><author><name sortKey="Duband, S" uniqKey="Duband S">S Duband</name></author><author><name sortKey="Pillet, S" uniqKey="Pillet S">S Pillet</name></author><author><name sortKey="Stachowicz, Ml" uniqKey="Stachowicz M">ML Stachowicz</name></author><author><name sortKey="Cornillon, J" uniqKey="Cornillon J">J Cornillon</name></author><author><name sortKey="Dumollard, Jm" uniqKey="Dumollard J">JM Dumollard</name></author><author><name sortKey="Peoc, M" uniqKey="Peoc M">M Peoc’h</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Fujino, K" uniqKey="Fujino K">K Fujino</name></author><author><name sortKey="Horie, M" uniqKey="Horie M">M Horie</name></author><author><name sortKey="Honda, T" uniqKey="Honda T">T Honda</name></author><author><name sortKey="Merriman, Dk" uniqKey="Merriman D">DK Merriman</name></author><author><name sortKey="Tomonaga, K" uniqKey="Tomonaga K">K Tomonaga</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Gagnon, A" uniqKey="Gagnon A">A Gagnon</name></author><author><name sortKey="Bouchard, Rw" uniqKey="Bouchard R">RW Bouchard</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ganesan, K" uniqKey="Ganesan K">K Ganesan</name></author><author><name sortKey="Diwan, A" uniqKey="Diwan A">A Diwan</name></author><author><name sortKey="Shankar, Sk" uniqKey="Shankar S">SK Shankar</name></author><author><name sortKey="Desai, Sb" uniqKey="Desai S">SB Desai</name></author><author><name sortKey="Sainani, Gs" uniqKey="Sainani G">GS Sainani</name></author><author><name sortKey="Katrak, Sm" uniqKey="Katrak S">SM Katrak</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Garen, Pd" uniqKey="Garen P">PD Garen</name></author><author><name sortKey="Tsai, Tf" uniqKey="Tsai T">TF Tsai</name></author><author><name sortKey="Powers, Jm" uniqKey="Powers J">JM Powers</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Gelpi, E" uniqKey="Gelpi E">E Gelpi</name></author><author><name sortKey="Preusser, M" uniqKey="Preusser M">M Preusser</name></author><author><name sortKey="Garzuly, F" uniqKey="Garzuly F">F Garzuly</name></author><author><name sortKey="Holzmann, H" uniqKey="Holzmann H">H Holzmann</name></author><author><name sortKey="Heinz, Fx" uniqKey="Heinz F">FX Heinz</name></author><author><name sortKey="Budka, H" uniqKey="Budka H">H Budka</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Gerardin, P" uniqKey="Gerardin P">P Gerardin</name></author><author><name sortKey="Barau, G" uniqKey="Barau G">G Barau</name></author><author><name sortKey="Michault, A" uniqKey="Michault A">A Michault</name></author><author><name sortKey="Bintner, M" uniqKey="Bintner M">M Bintner</name></author><author><name sortKey="Randrianaivo, H" uniqKey="Randrianaivo H">H Randrianaivo</name></author><author><name sortKey="Choker, G" uniqKey="Choker G">G Choker</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ghosh, Jb" uniqKey="Ghosh J">JB Ghosh</name></author><author><name sortKey="Roy, M" uniqKey="Roy M">M Roy</name></author><author><name sortKey="Lahiri, K" uniqKey="Lahiri K">K Lahiri</name></author><author><name sortKey="Bala, Ak" uniqKey="Bala A">AK Bala</name></author><author><name sortKey="Roy, M" uniqKey="Roy M">M Roy</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Gilden, D" uniqKey="Gilden D">D Gilden</name></author><author><name sortKey="Nagel, Ma" uniqKey="Nagel M">MA Nagel</name></author><author><name sortKey="Cohrs, Rj" uniqKey="Cohrs R">RJ Cohrs</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Glaser, Ca" uniqKey="Glaser C">CA Glaser</name></author><author><name sortKey="Winter, K" uniqKey="Winter K">K Winter</name></author><author><name sortKey="Dubray, K" uniqKey="Dubray K">K DuBray</name></author><author><name sortKey="Harriman, K" uniqKey="Harriman K">K Harriman</name></author><author><name sortKey="Uyeki, Tm" uniqKey="Uyeki T">TM Uyeki</name></author><author><name sortKey="Sejvar, J" uniqKey="Sejvar J">J Sejvar</name></author><author><name sortKey="Gilliam, S" uniqKey="Gilliam S">S Gilliam</name></author><author><name sortKey="Louie, Jk" uniqKey="Louie J">JK Louie</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Gowda, Vk" uniqKey="Gowda V">VK Gowda</name></author><author><name sortKey="Basavaraja, Gv" uniqKey="Basavaraja G">GV Basavaraja</name></author><author><name sortKey="Reddy, H" uniqKey="Reddy H">H Reddy</name></author><author><name sortKey="Ramaswamy, P" uniqKey="Ramaswamy P">P Ramaswamy</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Greninger, Al" uniqKey="Greninger A">AL Greninger</name></author><author><name sortKey="Naccache, Sn" uniqKey="Naccache S">SN Naccache</name></author><author><name sortKey="Messacar, K" uniqKey="Messacar K">K Messacar</name></author><author><name sortKey="Clayton, A" uniqKey="Clayton A">A Clayton</name></author><author><name sortKey="Yu, G" uniqKey="Yu G">G Yu</name></author><author><name sortKey="Somasekar, S" uniqKey="Somasekar S">S Somasekar</name></author><author><name sortKey="Federman, S" uniqKey="Federman S">S Federman</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Griffiths, Mj" uniqKey="Griffiths M">MJ Griffiths</name></author><author><name sortKey="Lemon, Jv" uniqKey="Lemon J">JV Lemon</name></author><author><name sortKey="Rayamajhi, A" uniqKey="Rayamajhi A">A Rayamajhi</name></author><author><name sortKey="Poudel, P" uniqKey="Poudel P">P Poudel</name></author><author><name sortKey="Shrestha, P" uniqKey="Shrestha P">P Shrestha</name></author><author><name sortKey="Srivastav, V" uniqKey="Srivastav V">V Srivastav</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Haddow, Ad" uniqKey="Haddow A">AD Haddow</name></author><author><name sortKey="Bixler, D" uniqKey="Bixler D">D Bixler</name></author><author><name sortKey="Odoi, A" uniqKey="Odoi A">A Odoi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Halliday, E" uniqKey="Halliday E">E Halliday</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hardie, Dr" uniqKey="Hardie D">DR Hardie</name></author><author><name sortKey="Albertyn, C" uniqKey="Albertyn C">C Albertyn</name></author><author><name sortKey="Heckmann, Jm" uniqKey="Heckmann J">JM Heckmann</name></author><author><name sortKey="Smuts, He" uniqKey="Smuts H">HE Smuts</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hartman, Al" uniqKey="Hartman A">AL Hartman</name></author><author><name sortKey="Powell, Ds" uniqKey="Powell D">DS Powell</name></author><author><name sortKey="Bethel, Lm" uniqKey="Bethel L">LM Bethel</name></author><author><name sortKey="Caroline, Al" uniqKey="Caroline A">AL Caroline</name></author><author><name sortKey="Schmid, Rj" uniqKey="Schmid R">RJ Schmid</name></author><author><name sortKey="Oury, T" uniqKey="Oury T">T Oury</name></author><author><name sortKey="Reed, Ds" uniqKey="Reed D">DS Reed</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hemachudha, T" uniqKey="Hemachudha T">T Hemachudha</name></author><author><name sortKey="Ugolini, G" uniqKey="Ugolini G">G Ugolini</name></author><author><name sortKey="Wacharapluesadee, S" uniqKey="Wacharapluesadee S">S Wacharapluesadee</name></author><author><name sortKey="Sungkarat, W" uniqKey="Sungkarat W">W Sungkarat</name></author><author><name sortKey="Shuangshoti, S" uniqKey="Shuangshoti S">S Shuangshoti</name></author><author><name sortKey="Laothamatas, J" uniqKey="Laothamatas J">J Laothamatas</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Herden, C" uniqKey="Herden C">C Herden</name></author><author><name sortKey="Briese, T" uniqKey="Briese T">T Briese</name></author><author><name sortKey="Lipkin, Wi" uniqKey="Lipkin W">WI Lipkin</name></author><author><name sortKey="Richt, Ja" uniqKey="Richt J">JA Richt</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hilbe, M" uniqKey="Hilbe M">M Hilbe</name></author><author><name sortKey="Herrsche, R" uniqKey="Herrsche R">R Herrsche</name></author><author><name sortKey="Kolodziejek, J" uniqKey="Kolodziejek J">J Kolodziejek</name></author><author><name sortKey="Nowotny, N" uniqKey="Nowotny N">N Nowotny</name></author><author><name sortKey="Zlinszky, K" uniqKey="Zlinszky K">K Zlinszky</name></author><author><name sortKey="Ehrensperger, F" uniqKey="Ehrensperger F">F Ehrensperger</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hoffmann, B" uniqKey="Hoffmann B">B Hoffmann</name></author><author><name sortKey="Tappe, D" uniqKey="Tappe D">D Tappe</name></author><author><name sortKey="Hoper, D" uniqKey="Hoper D">D Hoper</name></author><author><name sortKey="Herden, C" uniqKey="Herden C">C Herden</name></author><author><name sortKey="Boldt, A" uniqKey="Boldt A">A Boldt</name></author><author><name sortKey="Mawrin, C" uniqKey="Mawrin C">C Mawrin</name></author><author><name sortKey="Niederstrasser, O" uniqKey="Niederstrasser O">O Niederstrasser</name></author><author><name sortKey="Muller, T" uniqKey="Muller T">T Muller</name></author><author><name sortKey="Jenckel, M" uniqKey="Jenckel M">M Jenckel</name></author><author><name sortKey="Van Der Grinten, E" uniqKey="Van Der Grinten E">E van der Grinten</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Honkavuori, Ks" uniqKey="Honkavuori K">KS Honkavuori</name></author><author><name sortKey="Shivaprasad, Hl" uniqKey="Shivaprasad H">HL Shivaprasad</name></author><author><name sortKey="Williams, Bl" uniqKey="Williams B">BL Williams</name></author><author><name sortKey="Quan, Pl" uniqKey="Quan P">PL Quan</name></author><author><name sortKey="Hornig, M" uniqKey="Hornig M">M Hornig</name></author><author><name sortKey="Street, C" uniqKey="Street C">C Street</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Horie, M" uniqKey="Horie M">M Horie</name></author><author><name sortKey="Honda, T" uniqKey="Honda T">T Honda</name></author><author><name sortKey="Suzuki, Y" uniqKey="Suzuki Y">Y Suzuki</name></author><author><name sortKey="Kobayashi, Y" uniqKey="Kobayashi Y">Y Kobayashi</name></author><author><name sortKey="Daito, T" uniqKey="Daito T">T Daito</name></author><author><name sortKey="Oshida, T" uniqKey="Oshida T">T Oshida</name></author><author><name sortKey="Ikuta, K" uniqKey="Ikuta K">K Ikuta</name></author><author><name sortKey="Jern, P" uniqKey="Jern P">P Jern</name></author><author><name sortKey="Gojobori, T" uniqKey="Gojobori T">T Gojobori</name></author><author><name sortKey="Coffin, Jm" uniqKey="Coffin J">JM Coffin</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hornig, M" uniqKey="Hornig M">M Hornig</name></author><author><name sortKey="Briese, T" uniqKey="Briese T">T Briese</name></author><author><name sortKey="Licinio, J" uniqKey="Licinio J">J Licinio</name></author><author><name sortKey="Khabbaz, Rf" uniqKey="Khabbaz R">RF Khabbaz</name></author><author><name sortKey="Altshuler, Ll" uniqKey="Altshuler L">LL Altshuler</name></author><author><name sortKey="Potkin, Sg" uniqKey="Potkin S">SG Potkin</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Iwamasa, T" uniqKey="Iwamasa T">T Iwamasa</name></author><author><name sortKey="Yoshitake, H" uniqKey="Yoshitake H">H Yoshitake</name></author><author><name sortKey="Sakuda, H" uniqKey="Sakuda H">H Sakuda</name></author><author><name sortKey="Kamada, Y" uniqKey="Kamada Y">Y Kamada</name></author><author><name sortKey="Miyazato, M" uniqKey="Miyazato M">M Miyazato</name></author><author><name sortKey="Utsumi, Y" uniqKey="Utsumi Y">Y Utsumi</name></author><author><name sortKey="Nakamura, A" uniqKey="Nakamura A">A Nakamura</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Johnson, Km" uniqKey="Johnson K">KM Johnson</name></author><author><name sortKey="Martin, Dh" uniqKey="Martin D">DH Martin</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Johnstone, Ja" uniqKey="Johnstone J">JA Johnstone</name></author><author><name sortKey="Ross, Ca" uniqKey="Ross C">CA Ross</name></author><author><name sortKey="Dunn, M" uniqKey="Dunn M">M Dunn</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Joki Korpela, P" uniqKey="Joki Korpela P">P Joki-Korpela</name></author><author><name sortKey="Marjomaki, V" uniqKey="Marjomaki V">V Marjomaki</name></author><author><name sortKey="Krogerus, C" uniqKey="Krogerus C">C Krogerus</name></author><author><name sortKey="Heino, J" uniqKey="Heino J">J Heino</name></author><author><name sortKey="Hyypia, T" uniqKey="Hyypia T">T Hyypia</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kaiser, R" uniqKey="Kaiser R">R Kaiser</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kelley, Tw" uniqKey="Kelley T">TW Kelley</name></author><author><name sortKey="Prayson, Ra" uniqKey="Prayson R">RA Prayson</name></author><author><name sortKey="Ruiz, Ai" uniqKey="Ruiz A">AI Ruiz</name></author><author><name sortKey="Isada, Cm" uniqKey="Isada C">CM Isada</name></author><author><name sortKey="Gordon, Sm" uniqKey="Gordon S">SM Gordon</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kistler, Al" uniqKey="Kistler A">AL Kistler</name></author><author><name sortKey="Gancz, A" uniqKey="Gancz A">A Gancz</name></author><author><name sortKey="Clubb, S" uniqKey="Clubb S">S Clubb</name></author><author><name sortKey="Skewes Cox, P" uniqKey="Skewes Cox P">P Skewes-Cox</name></author><author><name sortKey="Fischer, K" uniqKey="Fischer K">K Fischer</name></author><author><name sortKey="Sorber, K" uniqKey="Sorber K">K Sorber</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Klein, Rs" uniqKey="Klein R">RS Klein</name></author><author><name sortKey="Lin, E" uniqKey="Lin E">E Lin</name></author><author><name sortKey="Zhang, B" uniqKey="Zhang B">B Zhang</name></author><author><name sortKey="Luster, Ad" uniqKey="Luster A">AD Luster</name></author><author><name sortKey="Tollett, J" uniqKey="Tollett J">J Tollett</name></author><author><name sortKey="Samuel, Ma" uniqKey="Samuel M">MA Samuel</name></author><author><name sortKey="Engle, M" uniqKey="Engle M">M Engle</name></author><author><name sortKey="Diamond, Ms" uniqKey="Diamond M">MS Diamond</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Korteweg, C" uniqKey="Korteweg C">C Korteweg</name></author><author><name sortKey="Gu, J" uniqKey="Gu J">J Gu</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kuiken, T" uniqKey="Kuiken T">T Kuiken</name></author><author><name sortKey="Taubenberger, Jk" uniqKey="Taubenberger J">JK Taubenberger</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Libraty, Dh" uniqKey="Libraty D">DH Libraty</name></author><author><name sortKey="Nisalak, A" uniqKey="Nisalak A">A Nisalak</name></author><author><name sortKey="Endy, Tp" uniqKey="Endy T">TP Endy</name></author><author><name sortKey="Suntayakorn, S" uniqKey="Suntayakorn S">S Suntayakorn</name></author><author><name sortKey="Vaughn, Dw" uniqKey="Vaughn D">DW Vaughn</name></author><author><name sortKey="Innis, Bl" uniqKey="Innis B">BL Innis</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lindquist, L" uniqKey="Lindquist L">L Lindquist</name></author><author><name sortKey="Vapalahti, O" uniqKey="Vapalahti O">O Vapalahti</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Love, S" uniqKey="Love S">S Love</name></author><author><name sortKey="Wiley, Ca" uniqKey="Wiley C">CA Wiley</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Ludlow, M" uniqKey="Ludlow M">M Ludlow</name></author><author><name sortKey="Duprex, Wp" uniqKey="Duprex W">WP Duprex</name></author><author><name sortKey="Cosby, Sl" uniqKey="Cosby S">SL Cosby</name></author><author><name sortKey="Allen, Iv" uniqKey="Allen I">IV Allen</name></author><author><name sortKey="Mcquaid, S" uniqKey="Mcquaid S">S McQuaid</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mansfield, Kl" uniqKey="Mansfield K">KL Mansfield</name></author><author><name sortKey="Johnson, N" uniqKey="Johnson N">N Johnson</name></author><author><name sortKey="Phipps, Lp" uniqKey="Phipps L">LP Phipps</name></author><author><name sortKey="Stephenson, Jr" uniqKey="Stephenson J">JR Stephenson</name></author><author><name sortKey="Fooks, Ar" uniqKey="Fooks A">AR Fooks</name></author><author><name sortKey="Solomon, T" uniqKey="Solomon T">T Solomon</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mardekian, Sk" uniqKey="Mardekian S">SK Mardekian</name></author><author><name sortKey="Fortuna, D" uniqKey="Fortuna D">D Fortuna</name></author><author><name sortKey="Nix, A" uniqKey="Nix A">A Nix</name></author><author><name sortKey="Bhatti, T" uniqKey="Bhatti T">T Bhatti</name></author><author><name sortKey="Wiley, Ca" uniqKey="Wiley C">CA Wiley</name></author><author><name sortKey="Flanders, A" uniqKey="Flanders A">A Flanders</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mcjunkin, Je" uniqKey="Mcjunkin J">JE McJunkin</name></author><author><name sortKey="De Los Reyes, Ec" uniqKey="De Los Reyes E">EC de los Reyes</name></author><author><name sortKey="Irazuzta, Je" uniqKey="Irazuzta J">JE Irazuzta</name></author><author><name sortKey="Caceres, Mj" uniqKey="Caceres M">MJ Caceres</name></author><author><name sortKey="Khan, Rr" uniqKey="Khan R">RR Khan</name></author><author><name sortKey="Minnich Ll, Ll" uniqKey="Minnich Ll L">LL Minnich LL</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mcquaid, S" uniqKey="Mcquaid S">S McQuaid</name></author><author><name sortKey="Cosby, Sl" uniqKey="Cosby S">SL Cosby</name></author><author><name sortKey="Koffi, K" uniqKey="Koffi K">K Koffi</name></author><author><name sortKey="Honde, M" uniqKey="Honde M">M Honde</name></author><author><name sortKey="Kirk, J" uniqKey="Kirk J">J Kirk</name></author><author><name sortKey="Lucas, Sb" uniqKey="Lucas S">SB Lucas</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Meyding Lamade, U" uniqKey="Meyding Lamade U">U Meyding-Lamade</name></author><author><name sortKey="Strank, C" uniqKey="Strank C">C Strank</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Miller, Hg" uniqKey="Miller H">HG Miller</name></author><author><name sortKey="Stanton, Jb" uniqKey="Stanton J">JB Stanton</name></author><author><name sortKey="Gibbons, Jl" uniqKey="Gibbons J">JL Gibbons</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mizuta, K" uniqKey="Mizuta K">K Mizuta</name></author><author><name sortKey="Kuroda, M" uniqKey="Kuroda M">M Kuroda</name></author><author><name sortKey="Kurimura, M" uniqKey="Kurimura M">M Kurimura</name></author><author><name sortKey="Yahata, Y" uniqKey="Yahata Y">Y Yahata</name></author><author><name sortKey="Sekizuka, T" uniqKey="Sekizuka T">T Sekizuka</name></author><author><name sortKey="Aoki, Y" uniqKey="Aoki Y">Y Aoki</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mohamed, M" uniqKey="Mohamed M">M Mohamed</name></author><author><name sortKey="Mosha, F" uniqKey="Mosha F">F Mosha</name></author><author><name sortKey="Mghamba, J" uniqKey="Mghamba J">J Mghamba</name></author><author><name sortKey="Zaki, Sr" uniqKey="Zaki S">SR Zaki</name></author><author><name sortKey="Shieh, Wj" uniqKey="Shieh W">WJ Shieh</name></author><author><name sortKey="Paweska, J" uniqKey="Paweska J">J Paweska</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Morimoto, K" uniqKey="Morimoto K">K Morimoto</name></author><author><name sortKey="Patel, M" uniqKey="Patel M">M Patel</name></author><author><name sortKey="Corisdeo, S" uniqKey="Corisdeo S">S Corisdeo</name></author><author><name sortKey="Hooper, Dc" uniqKey="Hooper D">DC Hooper</name></author><author><name sortKey="Fu, Zf" uniqKey="Fu Z">ZF Fu</name></author><author><name sortKey="Rupprecht, Ce" uniqKey="Rupprecht C">CE Rupprecht</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Morrow, Ji" uniqKey="Morrow J">JI Morrow</name></author><author><name sortKey="Dowey, Ke" uniqKey="Dowey K">KE Dowey</name></author><author><name sortKey="Swallow, Mw" uniqKey="Swallow M">MW Swallow</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mrak, Re" uniqKey="Mrak R">RE Mrak</name></author><author><name sortKey="Young, L" uniqKey="Young L">L Young</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Muehlenbachs, A" uniqKey="Muehlenbachs A">A Muehlenbachs</name></author><author><name sortKey="Bhatnagar, J" uniqKey="Bhatnagar J">J Bhatnagar</name></author><author><name sortKey="Zaki, Sr" uniqKey="Zaki S">SR Zaki</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Nagel, Ma" uniqKey="Nagel M">MA Nagel</name></author><author><name sortKey="Gilden, D" uniqKey="Gilden D">D Gilden</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Nagel, Ma" uniqKey="Nagel M">MA Nagel</name></author><author><name sortKey="Gilden, D" uniqKey="Gilden D">D Gilden</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Nash, D" uniqKey="Nash D">D Nash</name></author><author><name sortKey="Mostashari, F" uniqKey="Mostashari F">F Mostashari</name></author><author><name sortKey="Fine, A" uniqKey="Fine A">A Fine</name></author><author><name sortKey="Miller, J" uniqKey="Miller J">J Miller</name></author><author><name sortKey="O Eary, D" uniqKey="O Eary D">D O’Leary</name></author><author><name sortKey="Murray, K" uniqKey="Murray K">K Murray</name></author><author><name sortKey="Huang, A" uniqKey="Huang A">A Huang</name></author><author><name sortKey="Rosenberg, A" uniqKey="Rosenberg A">A Rosenberg</name></author><author><name sortKey="Greenberg, A" uniqKey="Greenberg A">A Greenberg</name></author><author><name sortKey="Sherman, M" uniqKey="Sherman M">M Sherman</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Nobach, D" uniqKey="Nobach D">D Nobach</name></author><author><name sortKey="Bourg, M" uniqKey="Bourg M">M Bourg</name></author><author><name sortKey="Herzog, S" uniqKey="Herzog S">S Herzog</name></author><author><name sortKey="Lange Herbst, H" uniqKey="Lange Herbst H">H Lange-Herbst</name></author><author><name sortKey="Encarnacao, Ja" uniqKey="Encarnacao J">JA Encarnacao</name></author><author><name sortKey="Eickmann, M" uniqKey="Eickmann M">M Eickmann</name></author><author><name sortKey="Herden, C" uniqKey="Herden C">C Herden</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="O Eary, Dr" uniqKey="O Eary D">DR O’Leary</name></author><author><name sortKey="Marfin, Aa" uniqKey="Marfin A">AA Marfin</name></author><author><name sortKey="Montgomery, Sp" uniqKey="Montgomery S">SP Montgomery</name></author><author><name sortKey="Kipp, Am" uniqKey="Kipp A">AM Kipp</name></author><author><name sortKey="Lehman, Ja" uniqKey="Lehman J">JA Lehman</name></author><author><name sortKey="Biggerstaff, Bj" uniqKey="Biggerstaff B">BJ Biggerstaff</name></author><author><name sortKey="Elko, Vl" uniqKey="Elko V">VL Elko</name></author><author><name sortKey="Collins, Pd" uniqKey="Collins P">PD Collins</name></author><author><name sortKey="Jones, Je" uniqKey="Jones J">JE Jones</name></author><author><name sortKey="Campbell, Gl" uniqKey="Campbell G">GL Campbell</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ooi, Mh" uniqKey="Ooi M">MH Ooi</name></author><author><name sortKey="Lewthwaite, P" uniqKey="Lewthwaite P">P Lewthwaite</name></author><author><name sortKey="Lai, Bf" uniqKey="Lai B">BF Lai</name></author><author><name sortKey="Mohan, A" uniqKey="Mohan A">A Mohan</name></author><author><name sortKey="Clear, D" uniqKey="Clear D">D Clear</name></author><author><name sortKey="Lim, L" uniqKey="Lim L">L Lim</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Palacios, G" uniqKey="Palacios G">G Palacios</name></author><author><name sortKey="Oberste, Ms" uniqKey="Oberste M">MS Oberste</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Parboosing, R" uniqKey="Parboosing R">R Parboosing</name></author><author><name sortKey="Bao, Y" uniqKey="Bao Y">Y Bao</name></author><author><name sortKey="Shen, L" uniqKey="Shen L">L Shen</name></author><author><name sortKey="Schaefer, Ca" uniqKey="Schaefer C">CA Schaefer</name></author><author><name sortKey="Brown, As" uniqKey="Brown A">AS Brown</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Pekosz, A" uniqKey="Pekosz A">A Pekosz</name></author><author><name sortKey="Phillips, J" uniqKey="Phillips J">J Phillips</name></author><author><name sortKey="Pleasure, D" uniqKey="Pleasure D">D Pleasure</name></author><author><name sortKey="Merry, D" uniqKey="Merry D">D Merry</name></author><author><name sortKey="Gonzalez Scarano, F" uniqKey="Gonzalez Scarano F">F Gonzalez-Scarano</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Pellett, Pe" uniqKey="Pellett P">PE Pellett</name></author><author><name sortKey="Roizman, B" uniqKey="Roizman B">B Roizman</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Perry, Rt" uniqKey="Perry R">RT Perry</name></author><author><name sortKey="Gacic Dobo, M" uniqKey="Gacic Dobo M">M Gacic-Dobo</name></author><author><name sortKey="Dabbagh, A" uniqKey="Dabbagh A">A Dabbagh</name></author><author><name sortKey="Mulders, Mn" uniqKey="Mulders M">MN Mulders</name></author><author><name sortKey="Strebel, Pm" uniqKey="Strebel P">PM Strebel</name></author><author><name sortKey="Okwo Bele, Jm" uniqKey="Okwo Bele J">JM Okwo-Bele</name></author><author><name sortKey="Rota, Pa" uniqKey="Rota P">PA Rota</name></author><author><name sortKey="Goodson, Jl" uniqKey="Goodson J">JL Goodson</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Powers, Am" uniqKey="Powers A">AM Powers</name></author><author><name sortKey="Oberste, Ms" uniqKey="Oberste M">MS Oberste</name></author><author><name sortKey="Brault, Ac" uniqKey="Brault A">AC Brault</name></author><author><name sortKey="Rico Hesse, R" uniqKey="Rico Hesse R">R Rico-Hesse</name></author><author><name sortKey="Schmura, Sm" uniqKey="Schmura S">SM Schmura</name></author><author><name sortKey="Smith, Jf" uniqKey="Smith J">JF Smith</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Racaniello, Vr" uniqKey="Racaniello V">VR Racaniello</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Rayamajhi, A" uniqKey="Rayamajhi A">A Rayamajhi</name></author><author><name sortKey="Singh, R" uniqKey="Singh R">R Singh</name></author><author><name sortKey="Prasad, R" uniqKey="Prasad R">R Prasad</name></author><author><name sortKey="Khanal, B" uniqKey="Khanal B">B Khanal</name></author><author><name sortKey="Singhi, S" uniqKey="Singhi S">S Singhi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Reid, Ah" uniqKey="Reid A">AH Reid</name></author><author><name sortKey="Mccall, S" uniqKey="Mccall S">S McCall</name></author><author><name sortKey="Henry, Jm" uniqKey="Henry J">JM Henry</name></author><author><name sortKey="Taubenberger, Jk" uniqKey="Taubenberger J">JK Taubenberger</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Reyes, Mg" uniqKey="Reyes M">MG Reyes</name></author><author><name sortKey="Gardner, Jj" uniqKey="Gardner J">JJ Gardner</name></author><author><name sortKey="Poland, Jd" uniqKey="Poland J">JD Poland</name></author><author><name sortKey="Monath, Tp" uniqKey="Monath T">TP Monath</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Rhoades, Re" uniqKey="Rhoades R">RE Rhoades</name></author><author><name sortKey="Tabor Godwin, Jm" uniqKey="Tabor Godwin J">JM Tabor-Godwin</name></author><author><name sortKey="Tsueng, G" uniqKey="Tsueng G">G Tsueng</name></author><author><name sortKey="Feuer, R" uniqKey="Feuer R">R Feuer</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Rodrigues, Sg" uniqKey="Rodrigues S">SG Rodrigues</name></author><author><name sortKey="Nunes, Mr" uniqKey="Nunes M">MR Nunes</name></author><author><name sortKey="Casseb, Sm" uniqKey="Casseb S">SM Casseb</name></author><author><name sortKey="Prazeres, As" uniqKey="Prazeres A">AS Prazeres</name></author><author><name sortKey="Rodrigues, Ds" uniqKey="Rodrigues D">DS Rodrigues</name></author><author><name sortKey="Silva, Mo" uniqKey="Silva M">MO Silva</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Rotbart, Ha" uniqKey="Rotbart H">HA Rotbart</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Russell, Rr" uniqKey="Russell R">RR Russell</name></author><author><name sortKey="Donald, Jc" uniqKey="Donald J">JC Donald</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ruzek, D" uniqKey="Ruzek D">D Ruzek</name></author><author><name sortKey="Dobler, G" uniqKey="Dobler G">G Dobler</name></author><author><name sortKey="Donoso Mantke, O" uniqKey="Donoso Mantke O">O Donoso Mantke</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Samuel, Ma" uniqKey="Samuel M">MA Samuel</name></author><author><name sortKey="Morrey, Jd" uniqKey="Morrey J">JD Morrey</name></author><author><name sortKey="Diamond, Ms" uniqKey="Diamond M">MS Diamond</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Santini, M" uniqKey="Santini M">M Santini</name></author><author><name sortKey="Kutlesa, M" uniqKey="Kutlesa M">M Kutlesa</name></author><author><name sortKey="Zarkovic, K" uniqKey="Zarkovic K">K Zarkovic</name></author><author><name sortKey="Drazenovic, V" uniqKey="Drazenovic V">V Drazenovic</name></author><author><name sortKey="Barsic, B" uniqKey="Barsic B">B Barsic</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Schonberger, K" uniqKey="Schonberger K">K Schonberger</name></author><author><name sortKey="Ludwig, Ms" uniqKey="Ludwig M">MS Ludwig</name></author><author><name sortKey="Wildner, M" uniqKey="Wildner M">M Wildner</name></author><author><name sortKey="Weissbrich, B" uniqKey="Weissbrich B">B Weissbrich</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sellner, J" uniqKey="Sellner J">J Sellner</name></author><author><name sortKey="Hemmer, B" uniqKey="Hemmer B">B Hemmer</name></author><author><name sortKey="Muhlau, M" uniqKey="Muhlau M">M Mühlau</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Selvey, La" uniqKey="Selvey L">LA Selvey</name></author><author><name sortKey="Wells, Rm" uniqKey="Wells R">RM Wells</name></author><author><name sortKey="Mccormack, Jg" uniqKey="Mccormack J">JG McCormack</name></author><author><name sortKey="Ansford, Aj" uniqKey="Ansford A">AJ Ansford</name></author><author><name sortKey="Murray, K" uniqKey="Murray K">K Murray</name></author><author><name sortKey="Rogers, Rj" uniqKey="Rogers R">RJ Rogers</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Shieh, Wj" uniqKey="Shieh W">WJ Shieh</name></author><author><name sortKey="Guarner, J" uniqKey="Guarner J">J Guarner</name></author><author><name sortKey="Layton, M" uniqKey="Layton M">M Layton</name></author><author><name sortKey="Fine, A" uniqKey="Fine A">A Fine</name></author><author><name sortKey="Miller, J" uniqKey="Miller J">J Miller</name></author><author><name sortKey="Nash, D" uniqKey="Nash D">D Nash</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Shuangshoti, S" uniqKey="Shuangshoti S">S Shuangshoti</name></author><author><name sortKey="Thepa, N" uniqKey="Thepa N">N Thepa</name></author><author><name sortKey="Phukpattaranont, P" uniqKey="Phukpattaranont P">P Phukpattaranont</name></author><author><name sortKey="Jittmittraphap, A" uniqKey="Jittmittraphap A">A Jittmittraphap</name></author><author><name sortKey="Intarut, N" uniqKey="Intarut N">N Intarut</name></author><author><name sortKey="Tepsumethanon, V" uniqKey="Tepsumethanon V">V Tepsumethanon</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Silverman, Ma" uniqKey="Silverman M">MA Silverman</name></author><author><name sortKey="Misasi, J" uniqKey="Misasi J">J Misasi</name></author><author><name sortKey="Smole, S" uniqKey="Smole S">S Smole</name></author><author><name sortKey="Feldman, Ha" uniqKey="Feldman H">HA Feldman</name></author><author><name sortKey="Cohen, Ab" uniqKey="Cohen A">AB Cohen</name></author><author><name sortKey="Santagata, S" uniqKey="Santagata S">S Santagata</name></author><author><name sortKey="Mcmanus, M" uniqKey="Mcmanus M">M McManus</name></author><author><name sortKey="Ahmed, Aa" uniqKey="Ahmed A">AA Ahmed</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Simon, M" uniqKey="Simon M">M Simon</name></author><author><name sortKey="Hernu, R" uniqKey="Hernu R">R Hernu</name></author><author><name sortKey="Cour, M" uniqKey="Cour M">M Cour</name></author><author><name sortKey="Casalegno, Js" uniqKey="Casalegno J">JS Casalegno</name></author><author><name sortKey="Lina, B" uniqKey="Lina B">B Lina</name></author><author><name sortKey="Argaud, L" uniqKey="Argaud L">L Argaud</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Smith, Dr" uniqKey="Smith D">DR Smith</name></author><author><name sortKey="Bird, Bh" uniqKey="Bird B">BH Bird</name></author><author><name sortKey="Lewis, B" uniqKey="Lewis B">B Lewis</name></author><author><name sortKey="Johnston, Sc" uniqKey="Johnston S">SC Johnston</name></author><author><name sortKey="Mccarthy, S" uniqKey="Mccarthy S">S McCarthy</name></author><author><name sortKey="Keeney, A" uniqKey="Keeney A">A Keeney</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Solomon, T" uniqKey="Solomon T">T Solomon</name></author><author><name sortKey="Dung, Nm" uniqKey="Dung N">NM Dung</name></author><author><name sortKey="Kneen, R" uniqKey="Kneen R">R Kneen</name></author><author><name sortKey="Le Thao, Tt" uniqKey="Le Thao T">TT le Thao</name></author><author><name sortKey="Gainsborough, M" uniqKey="Gainsborough M">M Gainsborough</name></author><author><name sortKey="Nisalak, A" uniqKey="Nisalak A">A Nisalak</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Solomon, T" uniqKey="Solomon T">T Solomon</name></author><author><name sortKey="Fisher, Af" uniqKey="Fisher A">AF Fisher</name></author><author><name sortKey="Beasley, Dw" uniqKey="Beasley D">DW Beasley</name></author><author><name sortKey="Mandava, P" uniqKey="Mandava P">P Mandava</name></author><author><name sortKey="Granwehr, Bp" uniqKey="Granwehr B">BP Granwehr</name></author><author><name sortKey="Langsjoen, H" uniqKey="Langsjoen H">H Langsjoen</name></author><author><name sortKey="Travassos Da Rosa, Ap" uniqKey="Travassos Da Rosa A">AP Travassos Da Rosa</name></author><author><name sortKey="Barrett, Ad" uniqKey="Barrett A">AD Barrett</name></author><author><name sortKey="Tesh, Rb" uniqKey="Tesh R">RB Tesh</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Solomon, T" uniqKey="Solomon T">T Solomon</name></author><author><name sortKey="Lewthwaite, P" uniqKey="Lewthwaite P">P Lewthwaite</name></author><author><name sortKey="Perera, D" uniqKey="Perera D">D Perera</name></author><author><name sortKey="Cardosa, Mj" uniqKey="Cardosa M">MJ Cardosa</name></author><author><name sortKey="Mcminn, P" uniqKey="Mcminn P">P McMinn</name></author><author><name sortKey="Ooi, Mh" uniqKey="Ooi M">MH Ooi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Solomon, T" uniqKey="Solomon T">T Solomon</name></author><author><name sortKey="Vaughn, Dw" uniqKey="Vaughn D">DW Vaughn</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Southern, Pm" uniqKey="Southern P">PM Southern</name></author><author><name sortKey="Smith, Jw" uniqKey="Smith J">JW Smith</name></author><author><name sortKey="Luby, Jp" uniqKey="Luby J">JP Luby</name></author><author><name sortKey="Barnett, Ja" uniqKey="Barnett J">JA Barnett</name></author><author><name sortKey="Sanford, Jp" uniqKey="Sanford J">JP Sanford</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Srinivasan, A" uniqKey="Srinivasan A">A Srinivasan</name></author><author><name sortKey="Burton, Ec" uniqKey="Burton E">EC Burton</name></author><author><name sortKey="Kuehnert, Mj" uniqKey="Kuehnert M">MJ Kuehnert</name></author><author><name sortKey="Rupprecht, C" uniqKey="Rupprecht C">C Rupprecht</name></author><author><name sortKey="Sutker, Wl" uniqKey="Sutker W">WL Sutker</name></author><author><name sortKey="Ksiazek, Tg" uniqKey="Ksiazek T">TG Ksiazek</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Steiner, I" uniqKey="Steiner I">I Steiner</name></author><author><name sortKey="Benninger, F" uniqKey="Benninger F">F Benninger</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Studahl, M" uniqKey="Studahl M">M Studahl</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Taira, N" uniqKey="Taira N">N Taira</name></author><author><name sortKey="Kamei, S" uniqKey="Kamei S">S Kamei</name></author><author><name sortKey="Morita, A" uniqKey="Morita A">A Morita</name></author><author><name sortKey="Ishihara, M" uniqKey="Ishihara M">M Ishihara</name></author><author><name sortKey="Miki, K" uniqKey="Miki K">K Miki</name></author><author><name sortKey="Shiota, H" uniqKey="Shiota H">H Shiota</name></author><author><name sortKey="Mizutani, T" uniqKey="Mizutani T">T Mizutani</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Tapparel, C" uniqKey="Tapparel C">C Tapparel</name></author><author><name sortKey="Siegrist, F" uniqKey="Siegrist F">F Siegrist</name></author><author><name sortKey="Petty, Tj" uniqKey="Petty T">TJ Petty</name></author><author><name sortKey="Kaiser, L" uniqKey="Kaiser L">L Kaiser</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Udow, Sj" uniqKey="Udow S">SJ Udow</name></author><author><name sortKey="Marrie, Ra" uniqKey="Marrie R">RA Marrie</name></author><author><name sortKey="Jackson, Ac" uniqKey="Jackson A">AC Jackson</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Van Marle, G" uniqKey="Van Marle G">G van Marle</name></author><author><name sortKey="Antony, J" uniqKey="Antony J">J Antony</name></author><author><name sortKey="Ostermann, H" uniqKey="Ostermann H">H Ostermann</name></author><author><name sortKey="Dunham, C" uniqKey="Dunham C">C Dunham</name></author><author><name sortKey="Hunt, T" uniqKey="Hunt T">T Hunt</name></author><author><name sortKey="Halliday, W" uniqKey="Halliday W">W Halliday</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Van Riel, D" uniqKey="Van Riel D">D van Riel</name></author><author><name sortKey="Leijten, Lm" uniqKey="Leijten L">LM Leijten</name></author><author><name sortKey="Verdijk, Rm" uniqKey="Verdijk R">RM Verdijk</name></author><author><name sortKey="Geurtsvankessel, C" uniqKey="Geurtsvankessel C">C GeurtsvanKessel</name></author><author><name sortKey="Van Der Vries, E" uniqKey="Van Der Vries E">E van der Vries</name></author><author><name sortKey="Van Rossum, Am" uniqKey="Van Rossum A">AM van Rossum</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Van Thiel, Pp" uniqKey="Van Thiel P">PP van Thiel</name></author><author><name sortKey="De Bie, Rm" uniqKey="De Bie R">RM de Bie</name></author><author><name sortKey="Eftimov, F" uniqKey="Eftimov F">F Eftimov</name></author><author><name sortKey="Tepaske, R" uniqKey="Tepaske R">R Tepaske</name></author><author><name sortKey="Zaaijer, Hl" uniqKey="Zaaijer H">HL Zaaijer</name></author><author><name sortKey="Van Doornum, Gj" uniqKey="Van Doornum G">GJ van Doornum</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Van Velden, Dj" uniqKey="Van Velden D">DJ van Velden</name></author><author><name sortKey="Meyer, Jd" uniqKey="Meyer J">JD Meyer</name></author><author><name sortKey="Olivier, J" uniqKey="Olivier J">J Olivier</name></author><author><name sortKey="Gear, Jh" uniqKey="Gear J">JH Gear</name></author><author><name sortKey="Mcintosh, B" uniqKey="Mcintosh B">B McIntosh</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Vandercam, T" uniqKey="Vandercam T">T Vandercam</name></author><author><name sortKey="Hintzen, Rq" uniqKey="Hintzen R">RQ Hintzen</name></author><author><name sortKey="De Boer, Jh" uniqKey="De Boer J">JH de Boer</name></author><author><name sortKey="Van Der Lelij, A" uniqKey="Van Der Lelij A">A Van der Lelij</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Verboon Maciolek, Ma" uniqKey="Verboon Maciolek M">MA Verboon-Maciolek</name></author><author><name sortKey="Groenendaal, F" uniqKey="Groenendaal F">F Groenendaal</name></author><author><name sortKey="Hahn, Cd" uniqKey="Hahn C">CD Hahn</name></author><author><name sortKey="Hellmann, J" uniqKey="Hellmann J">J Hellmann</name></author><author><name sortKey="Van Loon, Am" uniqKey="Van Loon A">AM van Loon</name></author><author><name sortKey="Boivin, G" uniqKey="Boivin G">G Boivin</name></author><author><name sortKey="De Vries, Ls" uniqKey="De Vries L">LS de Vries</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wasay, M" uniqKey="Wasay M">M Wasay</name></author><author><name sortKey="Diaz Arrastia, R" uniqKey="Diaz Arrastia R">R Diaz-Arrastia</name></author><author><name sortKey="Suss, Ra" uniqKey="Suss R">RA Suss</name></author><author><name sortKey="Kojan, S" uniqKey="Kojan S">S Kojan</name></author><author><name sortKey="Haq, A" uniqKey="Haq A">A Haq</name></author><author><name sortKey="Burns, D" uniqKey="Burns D">D Burns</name></author><author><name sortKey="Van Ness, P" uniqKey="Van Ness P">P Van Ness</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wassilak, Sgf" uniqKey="Wassilak S">SGF Wassilak</name></author><author><name sortKey="Oberste, Ms" uniqKey="Oberste M">MS Oberste</name></author><author><name sortKey="Tangermann, Rh" uniqKey="Tangermann R">RH Tangermann</name></author><author><name sortKey="Diop, Om" uniqKey="Diop O">OM Diop</name></author><author><name sortKey="Jafari, Hs" uniqKey="Jafari H">HS Jafari</name></author><author><name sortKey="Armstrong, Gl" uniqKey="Armstrong G">GL Armstrong</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Weaver, Sc" uniqKey="Weaver S">SC Weaver</name></author><author><name sortKey="Ferro, C" uniqKey="Ferro C">C Ferro</name></author><author><name sortKey="Barrera, R" uniqKey="Barrera R">R Barrera</name></author><author><name sortKey="Boshell, J" uniqKey="Boshell J">J Boshell</name></author><author><name sortKey="Navarro, Jc" uniqKey="Navarro J">JC Navarro</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Winkler, Wg" uniqKey="Winkler W">WG Winkler</name></author><author><name sortKey="Fashinell, Tr" uniqKey="Fashinell T">TR Fashinell</name></author><author><name sortKey="Leffingwell, L" uniqKey="Leffingwell L">L Leffingwell</name></author><author><name sortKey="Howard, P" uniqKey="Howard P">P Howard</name></author><author><name sortKey="Conomy, P" uniqKey="Conomy P">P Conomy</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Winter, Pm" uniqKey="Winter P">PM Winter</name></author><author><name sortKey="Dung, Nm" uniqKey="Dung N">NM Dung</name></author><author><name sortKey="Loan, Ht" uniqKey="Loan H">HT Loan</name></author><author><name sortKey="Kneen, R" uniqKey="Kneen R">R Kneen</name></author><author><name sortKey="Wills, B" uniqKey="Wills B">B Wills</name></author><author><name sortKey="Le Thu, T" uniqKey="Le Thu T">T le Thu</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wohlsein, P" uniqKey="Wohlsein P">P Wohlsein</name></author><author><name sortKey="Baumg Rtner, W" uniqKey="Baumg Rtner W">W Baumgärtner</name></author><author><name sortKey="Kreipe, Hh" uniqKey="Kreipe H">HH Kreipe</name></author><author><name sortKey="Haverich, A" uniqKey="Haverich A">A Haverich</name></author><author><name sortKey="Hori, A" uniqKey="Hori A">A Hori</name></author><author><name sortKey="Stan, Ac" uniqKey="Stan A">AC Stan</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wolthers, Kc" uniqKey="Wolthers K">KC Wolthers</name></author><author><name sortKey="Benschop, Ks" uniqKey="Benschop K">KS Benschop</name></author><author><name sortKey="Schinkel, J" uniqKey="Schinkel J">J Schinkel</name></author><author><name sortKey="Molenkamp, R" uniqKey="Molenkamp R">R Molenkamp</name></author><author><name sortKey="Bergevoet, Rm" uniqKey="Bergevoet R">RM Bergevoet</name></author><author><name sortKey="Spijkerman, Ij" uniqKey="Spijkerman I">IJ Spijkerman</name></author><author><name sortKey="Kraakman, Hc" uniqKey="Kraakman H">HC Kraakman</name></author><author><name sortKey="Pajkrt, D" uniqKey="Pajkrt D">D Pajkrt</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wong, Kt" uniqKey="Wong K">KT Wong</name></author><author><name sortKey="Munisamy, B" uniqKey="Munisamy B">B Munisamy</name></author><author><name sortKey="Ong, Kc" uniqKey="Ong K">KC Ong</name></author><author><name sortKey="Kojima, H" uniqKey="Kojima H">H Kojima</name></author><author><name sortKey="Noriyo, N" uniqKey="Noriyo N">N Noriyo</name></author><author><name sortKey="Chua, Kb" uniqKey="Chua K">KB Chua</name></author><author><name sortKey="Ong, Bb" uniqKey="Ong B">BB Ong</name></author><author><name sortKey="Nagashima, K" uniqKey="Nagashima K">K Nagashima</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wong, Kt" uniqKey="Wong K">KT Wong</name></author><author><name sortKey="Robertson, T" uniqKey="Robertson T">T Robertson</name></author><author><name sortKey="Ong, Bb" uniqKey="Ong B">BB Ong</name></author><author><name sortKey="Chong, Jw" uniqKey="Chong J">JW Chong</name></author><author><name sortKey="Yaiw, Kc" uniqKey="Yaiw K">KC Yaiw</name></author><author><name sortKey="Wang, Lf" uniqKey="Wang L">LF Wang</name></author><author><name sortKey="Ansford, Aj" uniqKey="Ansford A">AJ Ansford</name></author><author><name sortKey="Tannenberg, A" uniqKey="Tannenberg A">A Tannenberg</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wong, Kt" uniqKey="Wong K">KT Wong</name></author><author><name sortKey="Shieh, Wj" uniqKey="Shieh W">WJ Shieh</name></author><author><name sortKey="Kumar, S" uniqKey="Kumar S">S Kumar</name></author><author><name sortKey="Norain, K" uniqKey="Norain K">K Norain</name></author><author><name sortKey="Abdullah, W" uniqKey="Abdullah W">W Abdullah</name></author><author><name sortKey="Guarner, J" uniqKey="Guarner J">J Guarner</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wong, Kt" uniqKey="Wong K">KT Wong</name></author><author><name sortKey="Tan, Ct" uniqKey="Tan C">CT Tan</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wurtz, R" uniqKey="Wurtz R">R Wurtz</name></author><author><name sortKey="Paleologos, N" uniqKey="Paleologos N">N Paleologos</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Xiang, Z" uniqKey="Xiang Z">Z Xiang</name></author><author><name sortKey="Li, L" uniqKey="Li L">L Li</name></author><author><name sortKey="Lei, X" uniqKey="Lei X">X Lei</name></author><author><name sortKey="Zhou, H" uniqKey="Zhou H">H Zhou</name></author><author><name sortKey="Zhou, Z" uniqKey="Zhou Z">Z Zhou</name></author><author><name sortKey="He, B" uniqKey="He B">B He</name></author><author><name sortKey="Wang, J" uniqKey="Wang J">J Wang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Zhang, Sy" uniqKey="Zhang S">SY Zhang</name></author><author><name sortKey="Jouanguy, E" uniqKey="Jouanguy E">E Jouanguy</name></author><author><name sortKey="Ugolini, S" uniqKey="Ugolini S">S Ugolini</name></author><author><name sortKey="Smahi, A" uniqKey="Smahi A">A Smahi</name></author><author><name sortKey="Elain, G" uniqKey="Elain G">G Elain</name></author><author><name sortKey="Romero, P" uniqKey="Romero P">P Romero</name></author></analytic></biblStruct></listBibl></div1></back></TEI><pmc article-type="review-article"><pmc-dir>properties open_access</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-ta">Acta Neuropathol</journal-id><journal-id journal-id-type="iso-abbrev">Acta Neuropathol</journal-id><journal-title-group><journal-title>Acta Neuropathologica</journal-title></journal-title-group><issn pub-type="ppub">0001-6322</issn><issn pub-type="epub">1432-0533</issn><publisher><publisher-name>Springer Berlin Heidelberg</publisher-name><publisher-loc>Berlin/Heidelberg</publisher-loc></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">26659576</article-id><article-id pub-id-type="pmc">4713712</article-id><article-id pub-id-type="publisher-id">1511</article-id><article-id pub-id-type="doi">10.1007/s00401-015-1511-3</article-id><article-categories><subj-group subj-group-type="heading"><subject>Review</subject></subj-group></article-categories><title-group><article-title>Neurotropic virus infections as the cause of immediate and delayed neuropathology</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Ludlow</surname><given-names>Martin</given-names></name><xref ref-type="aff" rid="Aff1"></xref></contrib><contrib contrib-type="author"><name><surname>Kortekaas</surname><given-names>Jeroen</given-names></name><xref ref-type="aff" rid="Aff2"></xref></contrib><contrib contrib-type="author"><name><surname>Herden</surname><given-names>Christiane</given-names></name><xref ref-type="aff" rid="Aff3"></xref></contrib><contrib contrib-type="author"><name><surname>Hoffmann</surname><given-names>Bernd</given-names></name><xref ref-type="aff" rid="Aff4"></xref></contrib><contrib contrib-type="author"><name><surname>Tappe</surname><given-names>Dennis</given-names></name><xref ref-type="aff" rid="Aff5"></xref><xref ref-type="aff" rid="Aff6"></xref></contrib><contrib contrib-type="author"><name><surname>Trebst</surname><given-names>Corinna</given-names></name><xref ref-type="aff" rid="Aff7"></xref></contrib><contrib contrib-type="author"><name><surname>Griffin</surname><given-names>Diane E.</given-names></name><xref ref-type="aff" rid="Aff8"></xref></contrib><contrib contrib-type="author"><name><surname>Brindle</surname><given-names>Hannah E.</given-names></name><xref ref-type="aff" rid="Aff9"></xref><xref ref-type="aff" rid="Aff10"></xref></contrib><contrib contrib-type="author"><name><surname>Solomon</surname><given-names>Tom</given-names></name><xref ref-type="aff" rid="Aff9"></xref><xref ref-type="aff" rid="Aff11"></xref></contrib><contrib contrib-type="author"><name><surname>Brown</surname><given-names>Alan S.</given-names></name><xref ref-type="aff" rid="Aff12"></xref></contrib><contrib contrib-type="author"><name><surname>van Riel</surname><given-names>Debby</given-names></name><xref ref-type="aff" rid="Aff13"></xref></contrib><contrib contrib-type="author"><name><surname>Wolthers</surname><given-names>Katja C.</given-names></name><xref ref-type="aff" rid="Aff14"></xref></contrib><contrib contrib-type="author"><name><surname>Pajkrt</surname><given-names>Dasja</given-names></name><xref ref-type="aff" rid="Aff15"></xref></contrib><contrib contrib-type="author"><name><surname>Wohlsein</surname><given-names>Peter</given-names></name><xref ref-type="aff" rid="Aff16"></xref></contrib><contrib contrib-type="author"><name><surname>Martina</surname><given-names>Byron E. E.</given-names></name><xref ref-type="aff" rid="Aff13"></xref><xref ref-type="aff" rid="Aff17"></xref></contrib><contrib contrib-type="author"><name><surname>Baumgärtner</surname><given-names>Wolfgang</given-names></name><xref ref-type="aff" rid="Aff16"></xref><xref ref-type="aff" rid="Aff18"></xref></contrib><contrib contrib-type="author"><name><surname>Verjans</surname><given-names>Georges M.</given-names></name><xref ref-type="aff" rid="Aff1"></xref><xref ref-type="aff" rid="Aff13"></xref></contrib><contrib contrib-type="author" corresp="yes"><name><surname>Osterhaus</surname><given-names>Albert D. M. E.</given-names></name><address><email>albert.osterhaus@tiho-hannover.de</email></address><xref ref-type="aff" rid="Aff1"></xref><xref ref-type="aff" rid="Aff17"></xref><xref ref-type="aff" rid="Aff18"></xref></contrib><aff id="Aff1"><label></label>Research Center for Emerging Infections and Zoonoses, University of Veterinary Medicine, Bünteweg 17, 30559 Hannover, Germany</aff><aff id="Aff2"><label></label>Department of Virology, Central Veterinary Institute, Part of Wageningen University and Research Centre, Wageningen, The Netherlands</aff><aff id="Aff3"><label></label>Institute of Veterinary Pathology, Justus-Liebig-University Gießen, Giessen, Germany</aff><aff id="Aff4"><label></label>Institute of Diagnostic Virology, Friedrich-Loeffler-Institut, Greifswald-Insel Riems, Germany</aff><aff id="Aff5"><label></label>Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany</aff><aff id="Aff6"><label></label>German Centre for Infection Research (DZIF), Hamburg, Germany</aff><aff id="Aff7"><label></label>Department of Neurology, Hannover Medical School, Hannover, Germany</aff><aff id="Aff8"><label></label>W. Harry Feinstone Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD USA</aff><aff id="Aff9"><label></label>Institute of Infection and Global Health, University of Liverpool, Liverpool, UK</aff><aff id="Aff10"><label></label>Wellcome Trust Liverpool Glasgow Centre for Global Health Research, University of Liverpool, Liverpool, UK</aff><aff id="Aff11"><label></label>NIHR Health Protection Research Unit in Emerging Infection and Zoonoses, Liverpool, UK</aff><aff id="Aff12"><label></label>Department of Psychiatry, Columbia University Medical Center, New York State Psychiatric Institute, New York, NY USA</aff><aff id="Aff13"><label></label>Department of Viroscience, Erasmus MC, Rotterdam, The Netherlands</aff><aff id="Aff14"><label></label>Laboratory of Clinical Virology, Department of Medical Microbiology, Academic Medical Center, Amsterdam, The Netherlands</aff><aff id="Aff15"><label></label>Department of Pediatric Infectious Diseases, Emma Children’s Hospital, Academic Medical Center, Amsterdam, The Netherlands</aff><aff id="Aff16"><label></label>Department of Pathology, University of Veterinary Medicine, Hannover, Germany</aff><aff id="Aff17"><label></label>Artemis One Health, Utrecht, The Netherlands</aff><aff id="Aff18"><label></label>Center of Systems Neuroscience, Hannover, Germany</aff></contrib-group><pub-date pub-type="epub"><day>10</day><month>12</month><year>2015</year></pub-date><pub-date pub-type="pmc-release"><day>10</day><month>12</month><year>2015</year></pub-date><pub-date pub-type="ppub"><year>2016</year></pub-date><volume>131</volume><fpage>159</fpage><lpage>184</lpage><history><date date-type="received"><day>31</day><month>7</month><year>2015</year></date><date date-type="rev-recd"><day>24</day><month>10</month><year>2015</year></date><date date-type="accepted"><day>17</day><month>11</month><year>2015</year></date></history><permissions><copyright-statement>© The Author(s) 2015</copyright-statement><license license-type="OpenAccess"><license-p><bold>Open Access</bold>This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (<ext-link ext-link-type="uri" xlink:href="http://creativecommons.org/licenses/by/4.0/">http://creativecommons.org/licenses/by/4.0/</ext-link>), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.</license-p></license></permissions><abstract id="Abs1"><p>A wide range of viruses from different virus families in different geographical areas, may cause immediate or delayed neuropathological changes and neurological manifestations in humans and animals. Infection by neurotropic viruses as well as the resulting immune response can irreversibly disrupt the complex structural and functional architecture of the central nervous system, frequently leaving the patient or affected animal with a poor or fatal prognosis. Mechanisms that govern neuropathogenesis and immunopathogenesis of viral infections are highlighted, using examples of well-studied virus infections that are associated with these alterations in different populations throughout the world. A better understanding of the molecular, epidemiological and biological characteristics of these infections and in particular of mechanisms that underlie their clinical manifestations may be expected to provide tools for the development of more effective intervention strategies and treatment regimens.</p><sec><title>Electronic supplementary material</title><p>The online version of this article (doi:10.1007/s00401-015-1511-3) contains supplementary material, which is available to authorized users.</p></sec></abstract><kwd-group xml:lang="en"><title>Keywords</title><kwd>Central nervous system</kwd><kwd>Neuropathology</kwd><kwd>Neuroinfectiology</kwd><kwd>Virus infection</kwd><kwd>Alphavirus</kwd><kwd>Bornavirus</kwd><kwd>Bunyavirus</kwd><kwd>Flavivirus</kwd><kwd>Herpesvirus</kwd><kwd>Influenza virus</kwd><kwd>Paramyxovirus</kwd><kwd>Picornavirus</kwd><kwd>Rhabdovirus</kwd></kwd-group><funding-group><award-group><funding-source><institution-wrap><institution-id institution-id-type="FundRef">http://dx.doi.org/10.13039/501100001659</institution-id><institution>Deutsche Forschungsgemeinschaft (DE)</institution></institution-wrap></funding-source><award-id>Niedersachsen-Research Network on Neuroinfectiology (N-RENNT)</award-id><award-id>Niedersachsen-Research Network on Neuroinfectiology (N-RENNT)</award-id><award-id>Niedersachsen-Research Network on Neuroinfectiology (N-RENNT)</award-id><award-id>Niedersachsen-Research Network on Neuroinfectiology (N-RENNT)</award-id><award-id>Niedersachsen-Research Network on Neuroinfectiology (N-RENNT)</award-id><principal-award-recipient><name><surname>Ludlow</surname><given-names>Martin</given-names></name><name><surname>Wohlsein</surname><given-names>Peter</given-names></name><name><surname>Baumgärtner</surname><given-names>Wolfgang</given-names></name><name><surname>Verjans</surname><given-names>Georges M.</given-names></name><name><surname>Osterhaus</surname><given-names>Albert D. M. E.</given-names></name></principal-award-recipient></award-group><award-group><funding-source><institution-wrap><institution-id institution-id-type="FundRef">http://dx.doi.org/10.13039/501100004963</institution-id><institution>Seventh Framework Programme (BE)</institution></institution-wrap></funding-source><award-id>ASKLEPIOS, 602825</award-id><award-id>ASKLEPIOS, 602825</award-id><award-id>SILVER, 260644</award-id><award-id>SILVER, 260644</award-id><award-id>VECTORIE, 261466</award-id><award-id>VECTORIE, 261466</award-id><award-id>AIROPico, PIAPP-GA-2013-612308</award-id><principal-award-recipient><name><surname>Wolthers</surname><given-names>Katja C.</given-names></name><name><surname>Martina</surname><given-names>Byron E. E.</given-names></name><name><surname>Osterhaus</surname><given-names>Albert D. M. E.</given-names></name></principal-award-recipient></award-group><award-group><funding-source><institution>Horizon 2020 (EU)</institution></funding-source><award-id>COMPARE, 643476</award-id><award-id>COMPARE, 643476</award-id><award-id>ZAPI, 115760</award-id><award-id>ZAPI, 115760</award-id><award-id>ZAPI, 115760</award-id><principal-award-recipient><name><surname>Kortekaas</surname><given-names>Jeroen</given-names></name><name><surname>Baumgärtner</surname><given-names>Wolfgang</given-names></name><name><surname>Osterhaus</surname><given-names>Albert D. M. E.</given-names></name></principal-award-recipient></award-group><award-group><funding-source><institution-wrap><institution-id institution-id-type="FundRef">http://dx.doi.org/10.13039/501100000781</institution-id><institution>European Research Council (BE)</institution></institution-wrap></funding-source><award-id>FLUPLAN, 250136</award-id><principal-award-recipient><name><surname>Osterhaus</surname><given-names>Albert D. M. E.</given-names></name></principal-award-recipient></award-group><award-group><funding-source><institution-wrap><institution-id institution-id-type="FundRef">http://dx.doi.org/10.13039/100000002</institution-id><institution>National Institutes of Health (US)</institution></institution-wrap></funding-source><award-id>R01 NS087539</award-id><award-id>R01 NS038932</award-id><principal-award-recipient><name><surname>Griffin</surname><given-names>Diane E.</given-names></name></principal-award-recipient></award-group><award-group><funding-source><institution-wrap><institution-id institution-id-type="FundRef">http://dx.doi.org/10.13039/501100000272</institution-id><institution>National Institute for Health Research (GB)</institution></institution-wrap></funding-source><award-id>UK National Institute for Health Research Health Protection Research Unit in Emerging and Zoonotic Infections</award-id><award-id>UK National Institute for Health Research Health Protection Research Unit in Emerging and Zoonotic Infections</award-id><principal-award-recipient><name><surname>Brindle</surname><given-names>Hannah E.</given-names></name><name><surname>Solomon</surname><given-names>Tom</given-names></name></principal-award-recipient></award-group><award-group><funding-source><institution>Dutch Ministry of Economic Affairs</institution></funding-source><award-id>WOT-01-003-015</award-id><principal-award-recipient><name><surname>Kortekaas</surname><given-names>Jeroen</given-names></name></principal-award-recipient></award-group><award-group><funding-source><institution-wrap><institution-id institution-id-type="FundRef">http://dx.doi.org/10.13039/501100003246</institution-id><institution>Nederlandse Organisatie voor Wetenschappelijk Onderzoek (NL)</institution></institution-wrap></funding-source><award-id>NWO, 91614115</award-id><principal-award-recipient><name><surname>van Riel</surname><given-names>Debby</given-names></name></principal-award-recipient></award-group></funding-group><custom-meta-group><custom-meta><meta-name>issue-copyright-statement</meta-name><meta-value>© Springer-Verlag Berlin Heidelberg 2016</meta-value></custom-meta></custom-meta-group></article-meta></front></pmc><affiliations><list><country><li>Allemagne</li><li>Pays-Bas</li><li>Royaume-Uni</li><li>États-Unis</li></country><region><li>Basse-Saxe</li><li>Hambourg</li><li>Hollande-Méridionale</li><li>Hollande-Septentrionale</li><li>Maryland</li><li>Utrecht (province)</li><li>État de New York</li></region><settlement><li>Amsterdam</li><li>Hambourg</li><li>Hanovre</li><li>Rotterdam</li><li>Utrecht</li></settlement></list><tree><country name="Allemagne"><region name="Basse-Saxe"><name sortKey="Ludlow, Martin" sort="Ludlow, Martin" uniqKey="Ludlow M" first="Martin" last="Ludlow">Martin Ludlow</name></region><name sortKey="Baumg Rtner, Wolfgang" sort="Baumg Rtner, Wolfgang" uniqKey="Baumg Rtner W" first="Wolfgang" last="Baumg Rtner">Wolfgang Baumg Rtner</name><name sortKey="Baumg Rtner, Wolfgang" sort="Baumg Rtner, Wolfgang" uniqKey="Baumg Rtner W" first="Wolfgang" last="Baumg Rtner">Wolfgang Baumg Rtner</name><name sortKey="Herden, Christiane" sort="Herden, Christiane" uniqKey="Herden C" first="Christiane" last="Herden">Christiane Herden</name><name sortKey="Hoffmann, Bernd" sort="Hoffmann, Bernd" uniqKey="Hoffmann B" first="Bernd" last="Hoffmann">Bernd Hoffmann</name><name sortKey="Osterhaus, Albert D M E" sort="Osterhaus, Albert D M E" uniqKey="Osterhaus A" first="Albert D. M. E." last="Osterhaus">Albert D. M. E. Osterhaus</name><name sortKey="Osterhaus, Albert D M E" sort="Osterhaus, Albert D M E" uniqKey="Osterhaus A" first="Albert D. M. E." last="Osterhaus">Albert D. M. E. Osterhaus</name><name sortKey="Tappe, Dennis" sort="Tappe, Dennis" uniqKey="Tappe D" first="Dennis" last="Tappe">Dennis Tappe</name><name sortKey="Tappe, Dennis" sort="Tappe, Dennis" uniqKey="Tappe D" first="Dennis" last="Tappe">Dennis Tappe</name><name sortKey="Trebst, Corinna" sort="Trebst, Corinna" uniqKey="Trebst C" first="Corinna" last="Trebst">Corinna Trebst</name><name sortKey="Verjans, Georges M" sort="Verjans, Georges M" uniqKey="Verjans G" first="Georges M." last="Verjans">Georges M. Verjans</name><name sortKey="Wohlsein, Peter" sort="Wohlsein, Peter" uniqKey="Wohlsein P" first="Peter" last="Wohlsein">Peter Wohlsein</name></country><country name="Pays-Bas"><noRegion><name sortKey="Kortekaas, Jeroen" sort="Kortekaas, Jeroen" uniqKey="Kortekaas J" first="Jeroen" last="Kortekaas">Jeroen Kortekaas</name></noRegion><name sortKey="Martina, Byron E E" sort="Martina, Byron E E" uniqKey="Martina B" first="Byron E. E." last="Martina">Byron E. E. Martina</name><name sortKey="Martina, Byron E E" sort="Martina, Byron E E" uniqKey="Martina B" first="Byron E. E." last="Martina">Byron E. E. Martina</name><name sortKey="Osterhaus, Albert D M E" sort="Osterhaus, Albert D M E" uniqKey="Osterhaus A" first="Albert D. M. E." last="Osterhaus">Albert D. M. E. Osterhaus</name><name sortKey="Pajkrt, Dasja" sort="Pajkrt, Dasja" uniqKey="Pajkrt D" first="Dasja" last="Pajkrt">Dasja Pajkrt</name><name sortKey="Van Riel, Debby" sort="Van Riel, Debby" uniqKey="Van Riel D" first="Debby" last="Van Riel">Debby Van Riel</name><name sortKey="Verjans, Georges M" sort="Verjans, Georges M" uniqKey="Verjans G" first="Georges M." last="Verjans">Georges M. Verjans</name><name sortKey="Wolthers, Katja C" sort="Wolthers, Katja C" uniqKey="Wolthers K" first="Katja C." last="Wolthers">Katja C. Wolthers</name></country><country name="États-Unis"><region name="Maryland"><name sortKey="Griffin, Diane E" sort="Griffin, Diane E" uniqKey="Griffin D" first="Diane E." last="Griffin">Diane E. Griffin</name></region><name sortKey="Brown, Alan S" sort="Brown, Alan S" uniqKey="Brown A" first="Alan S." last="Brown">Alan S. Brown</name></country><country name="Royaume-Uni"><noRegion><name sortKey="Brindle, Hannah E" sort="Brindle, Hannah E" uniqKey="Brindle H" first="Hannah E." last="Brindle">Hannah E. Brindle</name></noRegion><name sortKey="Brindle, Hannah E" sort="Brindle, Hannah E" uniqKey="Brindle H" first="Hannah E." last="Brindle">Hannah E. Brindle</name><name sortKey="Solomon, Tom" sort="Solomon, Tom" uniqKey="Solomon T" first="Tom" last="Solomon">Tom Solomon</name><name sortKey="Solomon, Tom" sort="Solomon, Tom" uniqKey="Solomon T" first="Tom" last="Solomon">Tom Solomon</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/H2N2V1/Data/Pmc/Checkpoint
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000382 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Pmc/Checkpoint/biblio.hfd -nk 000382 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Sante
|area= H2N2V1
|flux= Pmc
|étape= Checkpoint
|type= RBID
|clé= PMC:4713712
|texte= Neurotropic virus infections as the cause of immediate and delayed neuropathology
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Pmc/Checkpoint/RBID.i -Sk "pubmed:26659576" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Pmc/Checkpoint/biblio.hfd \
| NlmPubMed2Wicri -a H2N2V1
| This area was generated with Dilib version V0.6.33. |  |