Evidence of a fixed internal gene constellation in influenza A viruses isolated from wild birds in Argentina (2006–2016)
Identifieur interne : 000153 ( Pmc/Checkpoint ); précédent : 000152; suivant : 000154Evidence of a fixed internal gene constellation in influenza A viruses isolated from wild birds in Argentina (2006–2016)
Auteurs : Agustina Rimondi ; Ana S. Gonzalez-Reiche [États-Unis] ; Valeria S. Olivera ; Julieta Decarre ; Gabriel J. Castresana ; Marcelo Romano ; Martha I. Nelson [États-Unis] ; Harm Van Bakel [États-Unis] ; Ariel J. Pereda ; Lucas Ferreri [États-Unis] ; Ginger Geiger [États-Unis] ; Daniel R. Perez [États-Unis]Source :
- Emerging Microbes & Infections [ 2222-1751 ] ; 2018.
Abstract
Wild aquatic birds are the major reservoir of influenza A virus. Cloacal swabs and feces samples (
Url:
DOI: 10.1038/s41426-018-0190-2
PubMed: 30482896
PubMed Central: 6258671
Affiliations:
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PMC:6258671Le document en format XML
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<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Evidence of a fixed internal gene constellation in influenza A viruses isolated from wild birds in Argentina (2006–2016)</title>
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<author><name sortKey="Castresana, Gabriel J" sort="Castresana, Gabriel J" uniqKey="Castresana G" first="Gabriel J." last="Castresana">Gabriel J. Castresana</name>
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<wicri:noCountry code="subfield">Buenos Aires Argentina</wicri:noCountry>
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<author><name sortKey="Romano, Marcelo" sort="Romano, Marcelo" uniqKey="Romano M" first="Marcelo" last="Romano">Marcelo Romano</name>
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<author><name sortKey="Van Bakel, Harm" sort="Van Bakel, Harm" uniqKey="Van Bakel H" first="Harm" last="Van Bakel">Harm Van Bakel</name>
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<author><name sortKey="Pereda, Ariel J" sort="Pereda, Ariel J" uniqKey="Pereda A" first="Ariel J." last="Pereda">Ariel J. Pereda</name>
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CC25 (1712) Castelar, Buenos Aires Argentina</nlm:aff>
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CC25 (1712) Castelar, Buenos Aires Argentina</nlm:aff>
<wicri:noCountry code="subfield">Buenos Aires Argentina</wicri:noCountry>
</affiliation>
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<author><name sortKey="Ferreri, Lucas" sort="Ferreri, Lucas" uniqKey="Ferreri L" first="Lucas" last="Ferreri">Lucas Ferreri</name>
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<author><name sortKey="Geiger, Ginger" sort="Geiger, Ginger" uniqKey="Geiger G" first="Ginger" last="Geiger">Ginger Geiger</name>
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<author><name sortKey="Perez, Daniel R" sort="Perez, Daniel R" uniqKey="Perez D" first="Daniel R." last="Perez">Daniel R. Perez</name>
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<series><title level="j">Emerging Microbes & Infections</title>
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<front><div type="abstract" xml:lang="en"><p id="Par1">Wild aquatic birds are the major reservoir of influenza A virus. Cloacal swabs and feces samples (<italic>n</italic>
= 6595) were collected from 62 bird species in Argentina from 2006 to 2016 and screened for influenza A virus. Full genome sequencing of 15 influenza isolates from 6 waterfowl species revealed subtypes combinations that were previously described in South America (H1N1, H4N2, H4N6 (<italic>n</italic>
= 3), H5N3, H6N2 (<italic>n</italic>
= 4), and H10N7 (<italic>n</italic>
= 2)), and new ones not previously identified in the region (H4N8, H7N7 and H7N9). Notably, the internal gene segments of all 15 Argentine isolates belonged to the South American lineage, showing a divergent evolution of these viruses in the Southern Hemisphere. Time-scaled phylogenies indicated that South American gene segments diverged between ~ 30 and ~ 140 years ago from the most closely related influenza lineages, which include the avian North American (PB1, HA, NA, MP, and NS-B) and Eurasian lineage (PB2), and the equine H3N8 lineage (PA, NP, and NS-A). Phylogenetic analyses of the hemagglutinin and neuraminidase gene segments of the H4, H6, and N8 subtypes revealed recent introductions and reassortment between viruses from the Northern and Southern Hemispheres in the Americas. Remarkably and despite evidence of recent hemagglutinin and neuraminidase subtype introductions, the phylogenetic composition of internal gene constellation of these influenza A viruses has remained unchanged. Considering the extended time and the number of sampled species of the current study, and the paucity of previously available data, our results contribute to a better understanding of the ecology and evolution of influenza virus in South America.</p>
</div>
</front>
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<author><name sortKey="Krauss, S" uniqKey="Krauss S">S Krauss</name>
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<pmc article-type="research-article"><pmc-dir>properties open_access</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-ta">Emerg Microbes Infect</journal-id>
<journal-id journal-id-type="iso-abbrev">Emerg Microbes Infect</journal-id>
<journal-title-group><journal-title>Emerging Microbes & Infections</journal-title>
</journal-title-group>
<issn pub-type="epub">2222-1751</issn>
<publisher><publisher-name>Nature Publishing Group UK</publisher-name>
<publisher-loc>London</publisher-loc>
</publisher>
</journal-meta>
<article-meta><article-id pub-id-type="pmid">30482896</article-id>
<article-id pub-id-type="pmc">6258671</article-id>
<article-id pub-id-type="publisher-id">190</article-id>
<article-id pub-id-type="doi">10.1038/s41426-018-0190-2</article-id>
<article-categories><subj-group subj-group-type="heading"><subject>Article</subject>
</subj-group>
</article-categories>
<title-group><article-title>Evidence of a fixed internal gene constellation in influenza A viruses isolated from wild birds in Argentina (2006–2016)</article-title>
</title-group>
<contrib-group><contrib contrib-type="author" corresp="yes"><name><surname>Rimondi</surname>
<given-names>Agustina</given-names>
</name>
<address><email>rimondi.agustina@inta.gob.ar</email>
</address>
<xref ref-type="aff" rid="Aff1">1</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Gonzalez-Reiche</surname>
<given-names>Ana S.</given-names>
</name>
<xref ref-type="aff" rid="Aff2">2</xref>
<xref ref-type="aff" rid="Aff7">7</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Olivera</surname>
<given-names>Valeria S.</given-names>
</name>
<xref ref-type="aff" rid="Aff1">1</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Decarre</surname>
<given-names>Julieta</given-names>
</name>
<xref ref-type="aff" rid="Aff3">3</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Castresana</surname>
<given-names>Gabriel J.</given-names>
</name>
<xref ref-type="aff" rid="Aff4">4</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Romano</surname>
<given-names>Marcelo</given-names>
</name>
<xref ref-type="aff" rid="Aff5">5</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Nelson</surname>
<given-names>Martha I.</given-names>
</name>
<xref ref-type="aff" rid="Aff6">6</xref>
</contrib>
<contrib contrib-type="author"><name><surname>van Bakel</surname>
<given-names>Harm</given-names>
</name>
<xref ref-type="aff" rid="Aff7">7</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Pereda</surname>
<given-names>Ariel J.</given-names>
</name>
<xref ref-type="aff" rid="Aff1">1</xref>
<xref ref-type="aff" rid="Aff8">8</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Ferreri</surname>
<given-names>Lucas</given-names>
</name>
<xref ref-type="aff" rid="Aff2">2</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Geiger</surname>
<given-names>Ginger</given-names>
</name>
<xref ref-type="aff" rid="Aff2">2</xref>
</contrib>
<contrib contrib-type="author"><contrib-id contrib-id-type="orcid">http://orcid.org/0000-0002-6569-5689</contrib-id>
<name><surname>Perez</surname>
<given-names>Daniel R.</given-names>
</name>
<address><email>dperez1@uga.edu</email>
</address>
<xref ref-type="aff" rid="Aff2">2</xref>
</contrib>
<aff id="Aff1"><label>1</label>
<institution-wrap><institution-id institution-id-type="GRID">grid.419231.c</institution-id>
<institution-id institution-id-type="ISNI">0000 0001 2167 7174</institution-id>
<institution>Instituto de Virologia CICVyA – Instituto Nacional de Tecnología Agropecuaria (INTA),</institution>
</institution-wrap>
CC25 (1712) Castelar, Buenos Aires Argentina</aff>
<aff id="Aff2"><label>2</label>
<institution-wrap><institution-id institution-id-type="ISNI">0000 0004 1936 738X</institution-id>
<institution-id institution-id-type="GRID">grid.213876.9</institution-id>
<institution>Poultry Diagnostic and Research Center, College of Veterinary Medicine,</institution>
<institution>University of Georgia,</institution>
</institution-wrap>
953 College Station Rd, Athens, GA 30602 USA</aff>
<aff id="Aff3"><label>3</label>
<institution-wrap><institution-id institution-id-type="GRID">grid.419231.c</institution-id>
<institution-id institution-id-type="ISNI">0000 0001 2167 7174</institution-id>
<institution>Instituto de Recursos Biológicos CIRN – Instituto Nacional de Tecnología Agropecuaria (INTA),</institution>
</institution-wrap>
CC25 (1712) Castelar, Buenos Aires Argentina</aff>
<aff id="Aff4"><label>4</label>
Dirección de Áreas Naturales Protegidas, Organismo Provincial para el Desarrollo Sostenible (O.P.D.S), Gobierno de la provincia de Buenos Aires, General Conesa, Buenos Aires Argentina</aff>
<aff id="Aff5"><label>5</label>
Centro de Investigaciones en Biodiversidad y Ambiente, Rosario (ECOSUR), Rosario, Santa Fe Argentina</aff>
<aff id="Aff6"><label>6</label>
<institution-wrap><institution-id institution-id-type="ISNI">0000 0001 2297 5165</institution-id>
<institution-id institution-id-type="GRID">grid.94365.3d</institution-id>
<institution>Fogarty International Center,</institution>
<institution>National Institutes of Health,</institution>
</institution-wrap>
Bethesda, MD 20894 USA</aff>
<aff id="Aff7"><label>7</label>
<institution-wrap><institution-id institution-id-type="ISNI">0000 0001 0670 2351</institution-id>
<institution-id institution-id-type="GRID">grid.59734.3c</institution-id>
<institution>Department of Genetics and Genomic Sciences,</institution>
<institution>Icahn School of Medicine at Mount Sinai,</institution>
</institution-wrap>
New York, NY 10029 USA</aff>
<aff id="Aff8"><label>8</label>
<institution-wrap><institution-id institution-id-type="GRID">grid.419231.c</institution-id>
<institution-id institution-id-type="ISNI">0000 0001 2167 7174</institution-id>
<institution>Present Address: Instituto de Patobiología CICVyA – Instituto Nacional de Tecnología Agropecuaria (INTA),</institution>
</institution-wrap>
CC25 (1712) Castelar, Buenos Aires Argentina</aff>
</contrib-group>
<pub-date pub-type="epub"><day>28</day>
<month>11</month>
<year>2018</year>
</pub-date>
<pub-date pub-type="pmc-release"><day>28</day>
<month>11</month>
<year>2018</year>
</pub-date>
<pub-date pub-type="collection"><year>2018</year>
</pub-date>
<volume>7</volume>
<elocation-id>194</elocation-id>
<history><date date-type="received"><day>26</day>
<month>7</month>
<year>2018</year>
</date>
<date date-type="rev-recd"><day>26</day>
<month>10</month>
<year>2018</year>
</date>
<date date-type="accepted"><day>31</day>
<month>10</month>
<year>2018</year>
</date>
</history>
<permissions><copyright-statement>© The Author(s) 2018</copyright-statement>
<license license-type="OpenAccess"><license-p><bold>Open Access</bold>
This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit <ext-link ext-link-type="uri" xlink:href="http://creativecommons.org/licenses/by/4.0/">http://creativecommons.org/licenses/by/4.0/</ext-link>
.</license-p>
</license>
</permissions>
<abstract id="Abs1"><p id="Par1">Wild aquatic birds are the major reservoir of influenza A virus. Cloacal swabs and feces samples (<italic>n</italic>
= 6595) were collected from 62 bird species in Argentina from 2006 to 2016 and screened for influenza A virus. Full genome sequencing of 15 influenza isolates from 6 waterfowl species revealed subtypes combinations that were previously described in South America (H1N1, H4N2, H4N6 (<italic>n</italic>
= 3), H5N3, H6N2 (<italic>n</italic>
= 4), and H10N7 (<italic>n</italic>
= 2)), and new ones not previously identified in the region (H4N8, H7N7 and H7N9). Notably, the internal gene segments of all 15 Argentine isolates belonged to the South American lineage, showing a divergent evolution of these viruses in the Southern Hemisphere. Time-scaled phylogenies indicated that South American gene segments diverged between ~ 30 and ~ 140 years ago from the most closely related influenza lineages, which include the avian North American (PB1, HA, NA, MP, and NS-B) and Eurasian lineage (PB2), and the equine H3N8 lineage (PA, NP, and NS-A). Phylogenetic analyses of the hemagglutinin and neuraminidase gene segments of the H4, H6, and N8 subtypes revealed recent introductions and reassortment between viruses from the Northern and Southern Hemispheres in the Americas. Remarkably and despite evidence of recent hemagglutinin and neuraminidase subtype introductions, the phylogenetic composition of internal gene constellation of these influenza A viruses has remained unchanged. Considering the extended time and the number of sampled species of the current study, and the paucity of previously available data, our results contribute to a better understanding of the ecology and evolution of influenza virus in South America.</p>
</abstract>
<funding-group><award-group><funding-source><institution-wrap><institution-id institution-id-type="FundRef">https://doi.org/10.13039/100000060</institution-id>
<institution>U.S. Department of Health & Human Services | NIH | National Institute of Allergy and Infectious Diseases (NIAID)</institution>
</institution-wrap>
</funding-source>
<award-id>HHSN266200700010C</award-id>
<award-id>HHSN272201400008C</award-id>
<principal-award-recipient><name><surname>Perez</surname>
<given-names>Daniel R.</given-names>
</name>
</principal-award-recipient>
</award-group>
</funding-group>
<funding-group><award-group><funding-source><institution-wrap><institution-id institution-id-type="FundRef">https://doi.org/10.13039/501100002923</institution-id>
<institution>Consejo Nacional de Investigaciones Científicas y Técnicas (National Scientific and Technical Research Council)</institution>
</institution-wrap>
</funding-source>
<award-id>PICT 2008 – 0922</award-id>
<principal-award-recipient><name><surname>Perez</surname>
<given-names>Daniel R.</given-names>
</name>
</principal-award-recipient>
</award-group>
</funding-group>
<custom-meta-group><custom-meta><meta-name>issue-copyright-statement</meta-name>
<meta-value>© The Author(s) 2018</meta-value>
</custom-meta>
</custom-meta-group>
</article-meta>
</front>
</pmc>
<affiliations><list><country><li>États-Unis</li>
</country>
<region><li>Géorgie (États-Unis)</li>
<li>Maryland</li>
<li>État de New York</li>
</region>
</list>
<tree><noCountry><name sortKey="Castresana, Gabriel J" sort="Castresana, Gabriel J" uniqKey="Castresana G" first="Gabriel J." last="Castresana">Gabriel J. Castresana</name>
<name sortKey="Decarre, Julieta" sort="Decarre, Julieta" uniqKey="Decarre J" first="Julieta" last="Decarre">Julieta Decarre</name>
<name sortKey="Olivera, Valeria S" sort="Olivera, Valeria S" uniqKey="Olivera V" first="Valeria S." last="Olivera">Valeria S. Olivera</name>
<name sortKey="Pereda, Ariel J" sort="Pereda, Ariel J" uniqKey="Pereda A" first="Ariel J." last="Pereda">Ariel J. Pereda</name>
<name sortKey="Rimondi, Agustina" sort="Rimondi, Agustina" uniqKey="Rimondi A" first="Agustina" last="Rimondi">Agustina Rimondi</name>
<name sortKey="Romano, Marcelo" sort="Romano, Marcelo" uniqKey="Romano M" first="Marcelo" last="Romano">Marcelo Romano</name>
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<country name="États-Unis"><region name="Géorgie (États-Unis)"><name sortKey="Gonzalez Reiche, Ana S" sort="Gonzalez Reiche, Ana S" uniqKey="Gonzalez Reiche A" first="Ana S." last="Gonzalez-Reiche">Ana S. Gonzalez-Reiche</name>
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<name sortKey="Ferreri, Lucas" sort="Ferreri, Lucas" uniqKey="Ferreri L" first="Lucas" last="Ferreri">Lucas Ferreri</name>
<name sortKey="Geiger, Ginger" sort="Geiger, Ginger" uniqKey="Geiger G" first="Ginger" last="Geiger">Ginger Geiger</name>
<name sortKey="Gonzalez Reiche, Ana S" sort="Gonzalez Reiche, Ana S" uniqKey="Gonzalez Reiche A" first="Ana S." last="Gonzalez-Reiche">Ana S. Gonzalez-Reiche</name>
<name sortKey="Nelson, Martha I" sort="Nelson, Martha I" uniqKey="Nelson M" first="Martha I." last="Nelson">Martha I. Nelson</name>
<name sortKey="Perez, Daniel R" sort="Perez, Daniel R" uniqKey="Perez D" first="Daniel R." last="Perez">Daniel R. Perez</name>
<name sortKey="Van Bakel, Harm" sort="Van Bakel, Harm" uniqKey="Van Bakel H" first="Harm" last="Van Bakel">Harm Van Bakel</name>
</country>
</tree>
</affiliations>
</record>
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