Serveur d'exploration H2N2

Attention, ce site est en cours de développement !
Attention, site généré par des moyens informatiques à partir de corpus bruts.
Les informations ne sont donc pas validées.

En Russe

Identifieur interne : 000062 ( PascalFrancis/Corpus ); précédent : 000061; suivant : 000063

En Russe

Auteurs : I. V. Kiseleva ; A. I. Klimov

Source :

RBID : Pascal:03-0248622

Descripteurs français

English descriptors

Abstract

Cold-adapted influenza viruses A/Leningrad/13 4/17/5 7 (H2N2) (Len/17) and A/Leningrad/ 34/4 7/57 (H2N2) (Len/ 47) are used in Russia to prepare live reassortant cold-adapted Influenza vaccines (LIV) for adults and children, respectively. Comparison between the nucleotide sequences of the Len/17 strain and the initial wild-type strain A/Leningrad/13 4/5 7 (H2N2) revealed ten nucleotide substitutions (eight of them encoding). Four additional substitutions (three encoding) were found in the genome of the Len/47 virus. Gene segment restriction site (PCR-restriction) analysis was used for identification of the genotype of reassortant Influenza viruses. Conventional methods of PCR-restriction analysis detect only five encoding nucleotide substitutions in the Internal genes of the Len/ 17 and seven substitutions in the internal genes of the Len/47 virus. An extended modification of the PCR-restriction method detect all encoding mutations in the internal genes of the Len/17 and Len/47 viruses (eight and eleven encoding substitutions, respectively). This method is advantageous for genome composition analysis of reassortant influenza vaccine strains and for investigating the genetic stability of LIV during replication In vaccines.

Notice en format standard (ISO 2709)

Pour connaître la documentation sur le format Inist Standard.

pA  
A01 01  1    @0 0507-4088
A02 01      @0 VVIRAT
A03   1    @0 Vopr. virusol.
A05       @2 47
A06       @2 6
A08 01  3  RUS  @1 En Russe
A11 01  1    @1 KISELEVA (I. V.)
A11 02  1    @1 KLIMOV (A. I.)
A20       @1 24-26
A21       @1 2002
A23 01      @0 RUS
A24 01      @0 eng
A43 01      @1 INIST @2 8812 @5 354000105612320060
A44       @0 0000 @1 © 2003 INIST-CNRS. All rights reserved.
A45       @0 5 ref.
A47 01  1    @0 03-0248622
A60       @1 P
A61       @0 A
A64 01  1    @0 Voprosy virusologii
A66 01      @0 RUS
A68 01  1  ENG  @1 Analysis of mutations in the genome of cold-adapted strains of influenza a virus using extended modification of polymerase chain reaction restriction method
C01 01    ENG  @0 Cold-adapted influenza viruses A/Leningrad/13 4/17/5 7 (H2N2) (Len/17) and A/Leningrad/ 34/4 7/57 (H2N2) (Len/ 47) are used in Russia to prepare live reassortant cold-adapted Influenza vaccines (LIV) for adults and children, respectively. Comparison between the nucleotide sequences of the Len/17 strain and the initial wild-type strain A/Leningrad/13 4/5 7 (H2N2) revealed ten nucleotide substitutions (eight of them encoding). Four additional substitutions (three encoding) were found in the genome of the Len/47 virus. Gene segment restriction site (PCR-restriction) analysis was used for identification of the genotype of reassortant Influenza viruses. Conventional methods of PCR-restriction analysis detect only five encoding nucleotide substitutions in the Internal genes of the Len/ 17 and seven substitutions in the internal genes of the Len/47 virus. An extended modification of the PCR-restriction method detect all encoding mutations in the internal genes of the Len/17 and Len/47 viruses (eight and eleven encoding substitutions, respectively). This method is advantageous for genome composition analysis of reassortant influenza vaccine strains and for investigating the genetic stability of LIV during replication In vaccines.
C02 01  X    @0 002A05C07
C03 01  X  FRE  @0 Influenzavirus A @2 NW @5 01
C03 01  X  ENG  @0 Influenzavirus A @2 NW @5 01
C03 01  X  SPA  @0 Influenzavirus A @2 NW @5 01
C03 02  X  FRE  @0 Virus grippal A @2 NW @5 02
C03 02  X  ENG  @0 Influenza A virus @2 NW @5 02
C03 02  X  SPA  @0 Influenza A virus @2 NW @5 02
C03 03  X  FRE  @0 Vaccin @5 05
C03 03  X  ENG  @0 Vaccine @5 05
C03 03  X  SPA  @0 Vacuna @5 05
C03 04  X  FRE  @0 Génotype @5 07
C03 04  X  ENG  @0 Genotype @5 07
C03 04  X  SPA  @0 Genotipo @5 07
C03 05  X  FRE  @0 Réaction chaîne polymérase @5 08
C03 05  X  ENG  @0 Polymerase chain reaction @5 08
C03 05  X  SPA  @0 Reacción cadena polimerasa @5 08
C03 06  X  FRE  @0 Mutation @5 09
C03 06  X  ENG  @0 Mutation @5 09
C03 06  X  SPA  @0 Mutación @5 09
C03 07  X  FRE  @0 Grippe A @5 14
C03 07  X  ENG  @0 Influenza A @5 14
C03 07  X  SPA  @0 Gripe A @5 14
C07 01  X  FRE  @0 Orthomyxoviridae @2 NW
C07 01  X  ENG  @0 Orthomyxoviridae @2 NW
C07 01  X  SPA  @0 Orthomyxoviridae @2 NW
C07 02  X  FRE  @0 Virus @2 NW
C07 02  X  ENG  @0 Virus @2 NW
C07 02  X  SPA  @0 Virus @2 NW
C07 03  X  FRE  @0 Virose
C07 03  X  ENG  @0 Viral disease
C07 03  X  SPA  @0 Virosis
C07 04  X  FRE  @0 Infection
C07 04  X  ENG  @0 Infection
C07 04  X  SPA  @0 Infección
N21       @1 160
N82       @1 PSI

Format Inist (serveur)

NO : PASCAL 03-0248622 INIST
ET : (Analysis of mutations in the genome of cold-adapted strains of influenza a virus using extended modification of polymerase chain reaction restriction method)
OT : En Russe
AU : KISELEVA (I. V.); KLIMOV (A. I.)
DT : Publication en série; Niveau analytique
SO : Voprosy virusologii; ISSN 0507-4088; Coden VVIRAT; Russie; Da. 2002; Vol. 47; No. 6; Pp. 24-26; Abs. anglais; Bibl. 5 ref.
LA : Russe
EA : Cold-adapted influenza viruses A/Leningrad/13 4/17/5 7 (H2N2) (Len/17) and A/Leningrad/ 34/4 7/57 (H2N2) (Len/ 47) are used in Russia to prepare live reassortant cold-adapted Influenza vaccines (LIV) for adults and children, respectively. Comparison between the nucleotide sequences of the Len/17 strain and the initial wild-type strain A/Leningrad/13 4/5 7 (H2N2) revealed ten nucleotide substitutions (eight of them encoding). Four additional substitutions (three encoding) were found in the genome of the Len/47 virus. Gene segment restriction site (PCR-restriction) analysis was used for identification of the genotype of reassortant Influenza viruses. Conventional methods of PCR-restriction analysis detect only five encoding nucleotide substitutions in the Internal genes of the Len/ 17 and seven substitutions in the internal genes of the Len/47 virus. An extended modification of the PCR-restriction method detect all encoding mutations in the internal genes of the Len/17 and Len/47 viruses (eight and eleven encoding substitutions, respectively). This method is advantageous for genome composition analysis of reassortant influenza vaccine strains and for investigating the genetic stability of LIV during replication In vaccines.
CC : 002A05C07
FD : Influenzavirus A; Virus grippal A; Vaccin; Génotype; Réaction chaîne polymérase; Mutation; Grippe A
FG : Orthomyxoviridae; Virus; Virose; Infection
ED : Influenzavirus A; Influenza A virus; Vaccine; Genotype; Polymerase chain reaction; Mutation; Influenza A
EG : Orthomyxoviridae; Virus; Viral disease; Infection
SD : Influenzavirus A; Influenza A virus; Vacuna; Genotipo; Reacción cadena polimerasa; Mutación; Gripe A
LO : INIST-8812.354000105612320060
ID : 03-0248622

Links to Exploration step

Pascal:03-0248622

Le document en format XML

<record>
<TEI>
<teiHeader>
<fileDesc>
<titleStmt>
<title xml:lang="RUS" level="a">En Russe</title>
<author>
<name sortKey="Kiseleva, I V" sort="Kiseleva, I V" uniqKey="Kiseleva I" first="I. V." last="Kiseleva">I. V. Kiseleva</name>
<affiliation>
<wicri:noCountry>no AF</wicri:noCountry>
</affiliation>
</author>
<author>
<name sortKey="Klimov, A I" sort="Klimov, A I" uniqKey="Klimov A" first="A. I." last="Klimov">A. I. Klimov</name>
<affiliation>
<wicri:noCountry>no AF</wicri:noCountry>
</affiliation>
</author>
</titleStmt>
<publicationStmt>
<idno type="wicri:source">INIST</idno>
<idno type="inist">03-0248622</idno>
<date when="2002">2002</date>
<idno type="stanalyst">PASCAL 03-0248622 INIST</idno>
<idno type="RBID">Pascal:03-0248622</idno>
<idno type="wicri:Area/PascalFrancis/Corpus">000062</idno>
</publicationStmt>
<sourceDesc>
<biblStruct>
<analytic>
<title xml:lang="RUS" level="a">En Russe</title>
<author>
<name sortKey="Kiseleva, I V" sort="Kiseleva, I V" uniqKey="Kiseleva I" first="I. V." last="Kiseleva">I. V. Kiseleva</name>
<affiliation>
<wicri:noCountry>no AF</wicri:noCountry>
</affiliation>
</author>
<author>
<name sortKey="Klimov, A I" sort="Klimov, A I" uniqKey="Klimov A" first="A. I." last="Klimov">A. I. Klimov</name>
<affiliation>
<wicri:noCountry>no AF</wicri:noCountry>
</affiliation>
</author>
</analytic>
<series>
<title level="j" type="main">Voprosy virusologii</title>
<title level="j" type="abbreviated">Vopr. virusol.</title>
<idno type="ISSN">0507-4088</idno>
<imprint>
<date when="2002">2002</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
<seriesStmt>
<title level="j" type="main">Voprosy virusologii</title>
<title level="j" type="abbreviated">Vopr. virusol.</title>
<idno type="ISSN">0507-4088</idno>
</seriesStmt>
</fileDesc>
<profileDesc>
<textClass>
<keywords scheme="KwdEn" xml:lang="en">
<term>Genotype</term>
<term>Influenza A</term>
<term>Influenza A virus</term>
<term>Influenzavirus A</term>
<term>Mutation</term>
<term>Polymerase chain reaction</term>
<term>Vaccine</term>
</keywords>
<keywords scheme="Pascal" xml:lang="fr">
<term>Influenzavirus A</term>
<term>Virus grippal A</term>
<term>Vaccin</term>
<term>Génotype</term>
<term>Réaction chaîne polymérase</term>
<term>Mutation</term>
<term>Grippe A</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front>
<div type="abstract" xml:lang="en">Cold-adapted influenza viruses A/Leningrad/13 4/17/5 7 (H2N2) (Len/17) and A/Leningrad/ 34/4 7/57 (H2N2) (Len/ 47) are used in Russia to prepare live reassortant cold-adapted Influenza vaccines (LIV) for adults and children, respectively. Comparison between the nucleotide sequences of the Len/17 strain and the initial wild-type strain A/Leningrad/13 4/5 7 (H2N2) revealed ten nucleotide substitutions (eight of them encoding). Four additional substitutions (three encoding) were found in the genome of the Len/47 virus. Gene segment restriction site (PCR-restriction) analysis was used for identification of the genotype of reassortant Influenza viruses. Conventional methods of PCR-restriction analysis detect only five encoding nucleotide substitutions in the Internal genes of the Len/ 17 and seven substitutions in the internal genes of the Len/47 virus. An extended modification of the PCR-restriction method detect all encoding mutations in the internal genes of the Len/17 and Len/47 viruses (eight and eleven encoding substitutions, respectively). This method is advantageous for genome composition analysis of reassortant influenza vaccine strains and for investigating the genetic stability of LIV during replication In vaccines.</div>
</front>
</TEI>
<inist>
<standard h6="B">
<pA>
<fA01 i1="01" i2="1">
<s0>0507-4088</s0>
</fA01>
<fA02 i1="01">
<s0>VVIRAT</s0>
</fA02>
<fA03 i2="1">
<s0>Vopr. virusol.</s0>
</fA03>
<fA05>
<s2>47</s2>
</fA05>
<fA06>
<s2>6</s2>
</fA06>
<fA08 i1="01" i2="3" l="RUS">
<s1>En Russe</s1>
</fA08>
<fA11 i1="01" i2="1">
<s1>KISELEVA (I. V.)</s1>
</fA11>
<fA11 i1="02" i2="1">
<s1>KLIMOV (A. I.)</s1>
</fA11>
<fA20>
<s1>24-26</s1>
</fA20>
<fA21>
<s1>2002</s1>
</fA21>
<fA23 i1="01">
<s0>RUS</s0>
</fA23>
<fA24 i1="01">
<s0>eng</s0>
</fA24>
<fA43 i1="01">
<s1>INIST</s1>
<s2>8812</s2>
<s5>354000105612320060</s5>
</fA43>
<fA44>
<s0>0000</s0>
<s1>© 2003 INIST-CNRS. All rights reserved.</s1>
</fA44>
<fA45>
<s0>5 ref.</s0>
</fA45>
<fA47 i1="01" i2="1">
<s0>03-0248622</s0>
</fA47>
<fA60>
<s1>P</s1>
</fA60>
<fA61>
<s0>A</s0>
</fA61>
<fA64 i1="01" i2="1">
<s0>Voprosy virusologii</s0>
</fA64>
<fA66 i1="01">
<s0>RUS</s0>
</fA66>
<fA68 i1="01" i2="1" l="ENG">
<s1>Analysis of mutations in the genome of cold-adapted strains of influenza a virus using extended modification of polymerase chain reaction restriction method</s1>
</fA68>
<fC01 i1="01" l="ENG">
<s0>Cold-adapted influenza viruses A/Leningrad/13 4/17/5 7 (H2N2) (Len/17) and A/Leningrad/ 34/4 7/57 (H2N2) (Len/ 47) are used in Russia to prepare live reassortant cold-adapted Influenza vaccines (LIV) for adults and children, respectively. Comparison between the nucleotide sequences of the Len/17 strain and the initial wild-type strain A/Leningrad/13 4/5 7 (H2N2) revealed ten nucleotide substitutions (eight of them encoding). Four additional substitutions (three encoding) were found in the genome of the Len/47 virus. Gene segment restriction site (PCR-restriction) analysis was used for identification of the genotype of reassortant Influenza viruses. Conventional methods of PCR-restriction analysis detect only five encoding nucleotide substitutions in the Internal genes of the Len/ 17 and seven substitutions in the internal genes of the Len/47 virus. An extended modification of the PCR-restriction method detect all encoding mutations in the internal genes of the Len/17 and Len/47 viruses (eight and eleven encoding substitutions, respectively). This method is advantageous for genome composition analysis of reassortant influenza vaccine strains and for investigating the genetic stability of LIV during replication In vaccines.</s0>
</fC01>
<fC02 i1="01" i2="X">
<s0>002A05C07</s0>
</fC02>
<fC03 i1="01" i2="X" l="FRE">
<s0>Influenzavirus A</s0>
<s2>NW</s2>
<s5>01</s5>
</fC03>
<fC03 i1="01" i2="X" l="ENG">
<s0>Influenzavirus A</s0>
<s2>NW</s2>
<s5>01</s5>
</fC03>
<fC03 i1="01" i2="X" l="SPA">
<s0>Influenzavirus A</s0>
<s2>NW</s2>
<s5>01</s5>
</fC03>
<fC03 i1="02" i2="X" l="FRE">
<s0>Virus grippal A</s0>
<s2>NW</s2>
<s5>02</s5>
</fC03>
<fC03 i1="02" i2="X" l="ENG">
<s0>Influenza A virus</s0>
<s2>NW</s2>
<s5>02</s5>
</fC03>
<fC03 i1="02" i2="X" l="SPA">
<s0>Influenza A virus</s0>
<s2>NW</s2>
<s5>02</s5>
</fC03>
<fC03 i1="03" i2="X" l="FRE">
<s0>Vaccin</s0>
<s5>05</s5>
</fC03>
<fC03 i1="03" i2="X" l="ENG">
<s0>Vaccine</s0>
<s5>05</s5>
</fC03>
<fC03 i1="03" i2="X" l="SPA">
<s0>Vacuna</s0>
<s5>05</s5>
</fC03>
<fC03 i1="04" i2="X" l="FRE">
<s0>Génotype</s0>
<s5>07</s5>
</fC03>
<fC03 i1="04" i2="X" l="ENG">
<s0>Genotype</s0>
<s5>07</s5>
</fC03>
<fC03 i1="04" i2="X" l="SPA">
<s0>Genotipo</s0>
<s5>07</s5>
</fC03>
<fC03 i1="05" i2="X" l="FRE">
<s0>Réaction chaîne polymérase</s0>
<s5>08</s5>
</fC03>
<fC03 i1="05" i2="X" l="ENG">
<s0>Polymerase chain reaction</s0>
<s5>08</s5>
</fC03>
<fC03 i1="05" i2="X" l="SPA">
<s0>Reacción cadena polimerasa</s0>
<s5>08</s5>
</fC03>
<fC03 i1="06" i2="X" l="FRE">
<s0>Mutation</s0>
<s5>09</s5>
</fC03>
<fC03 i1="06" i2="X" l="ENG">
<s0>Mutation</s0>
<s5>09</s5>
</fC03>
<fC03 i1="06" i2="X" l="SPA">
<s0>Mutación</s0>
<s5>09</s5>
</fC03>
<fC03 i1="07" i2="X" l="FRE">
<s0>Grippe A</s0>
<s5>14</s5>
</fC03>
<fC03 i1="07" i2="X" l="ENG">
<s0>Influenza A</s0>
<s5>14</s5>
</fC03>
<fC03 i1="07" i2="X" l="SPA">
<s0>Gripe A</s0>
<s5>14</s5>
</fC03>
<fC07 i1="01" i2="X" l="FRE">
<s0>Orthomyxoviridae</s0>
<s2>NW</s2>
</fC07>
<fC07 i1="01" i2="X" l="ENG">
<s0>Orthomyxoviridae</s0>
<s2>NW</s2>
</fC07>
<fC07 i1="01" i2="X" l="SPA">
<s0>Orthomyxoviridae</s0>
<s2>NW</s2>
</fC07>
<fC07 i1="02" i2="X" l="FRE">
<s0>Virus</s0>
<s2>NW</s2>
</fC07>
<fC07 i1="02" i2="X" l="ENG">
<s0>Virus</s0>
<s2>NW</s2>
</fC07>
<fC07 i1="02" i2="X" l="SPA">
<s0>Virus</s0>
<s2>NW</s2>
</fC07>
<fC07 i1="03" i2="X" l="FRE">
<s0>Virose</s0>
</fC07>
<fC07 i1="03" i2="X" l="ENG">
<s0>Viral disease</s0>
</fC07>
<fC07 i1="03" i2="X" l="SPA">
<s0>Virosis</s0>
</fC07>
<fC07 i1="04" i2="X" l="FRE">
<s0>Infection</s0>
</fC07>
<fC07 i1="04" i2="X" l="ENG">
<s0>Infection</s0>
</fC07>
<fC07 i1="04" i2="X" l="SPA">
<s0>Infección</s0>
</fC07>
<fN21>
<s1>160</s1>
</fN21>
<fN82>
<s1>PSI</s1>
</fN82>
</pA>
</standard>
<server>
<NO>PASCAL 03-0248622 INIST</NO>
<ET>(Analysis of mutations in the genome of cold-adapted strains of influenza a virus using extended modification of polymerase chain reaction restriction method)</ET>
<OT>En Russe</OT>
<AU>KISELEVA (I. V.); KLIMOV (A. I.)</AU>
<DT>Publication en série; Niveau analytique</DT>
<SO>Voprosy virusologii; ISSN 0507-4088; Coden VVIRAT; Russie; Da. 2002; Vol. 47; No. 6; Pp. 24-26; Abs. anglais; Bibl. 5 ref.</SO>
<LA>Russe</LA>
<EA>Cold-adapted influenza viruses A/Leningrad/13 4/17/5 7 (H2N2) (Len/17) and A/Leningrad/ 34/4 7/57 (H2N2) (Len/ 47) are used in Russia to prepare live reassortant cold-adapted Influenza vaccines (LIV) for adults and children, respectively. Comparison between the nucleotide sequences of the Len/17 strain and the initial wild-type strain A/Leningrad/13 4/5 7 (H2N2) revealed ten nucleotide substitutions (eight of them encoding). Four additional substitutions (three encoding) were found in the genome of the Len/47 virus. Gene segment restriction site (PCR-restriction) analysis was used for identification of the genotype of reassortant Influenza viruses. Conventional methods of PCR-restriction analysis detect only five encoding nucleotide substitutions in the Internal genes of the Len/ 17 and seven substitutions in the internal genes of the Len/47 virus. An extended modification of the PCR-restriction method detect all encoding mutations in the internal genes of the Len/17 and Len/47 viruses (eight and eleven encoding substitutions, respectively). This method is advantageous for genome composition analysis of reassortant influenza vaccine strains and for investigating the genetic stability of LIV during replication In vaccines.</EA>
<CC>002A05C07</CC>
<FD>Influenzavirus A; Virus grippal A; Vaccin; Génotype; Réaction chaîne polymérase; Mutation; Grippe A</FD>
<FG>Orthomyxoviridae; Virus; Virose; Infection</FG>
<ED>Influenzavirus A; Influenza A virus; Vaccine; Genotype; Polymerase chain reaction; Mutation; Influenza A</ED>
<EG>Orthomyxoviridae; Virus; Viral disease; Infection</EG>
<SD>Influenzavirus A; Influenza A virus; Vacuna; Genotipo; Reacción cadena polimerasa; Mutación; Gripe A</SD>
<LO>INIST-8812.354000105612320060</LO>
<ID>03-0248622</ID>
</server>
</inist>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Sante/explor/H2N2V1/Data/PascalFrancis/Corpus
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000062 | SxmlIndent | more

Ou

HfdSelect -h $EXPLOR_AREA/Data/PascalFrancis/Corpus/biblio.hfd -nk 000062 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Sante
   |area=    H2N2V1
   |flux=    PascalFrancis
   |étape=   Corpus
   |type=    RBID
   |clé=     Pascal:03-0248622
   |texte=   En Russe
}}

Wicri

This area was generated with Dilib version V0.6.33.
Data generation: Tue Apr 14 19:59:40 2020. Site generation: Thu Mar 25 15:38:26 2021