Influenza
Identifieur interne : 001034 ( Ncbi/Merge ); précédent : 001033; suivant : 001035Influenza
Auteurs : Dhanya DharmapalanSource :
- Indian Journal of Pediatrics [ 0019-5456 ] ; 2020.
Abstract
Influenza continues to baffle humans by its constantly changing nature. The twenty-first century has witnessed considerable advances in the understanding of the influenza viral pathogenesis, its synergy with bacterial infections and diagnostic methods. However, challenges continue: to find a less expensive and more reliable point-of-care test for use in developing countries, to produce more efficacious antiviral drugs, to explore ways to combat emerging antiviral resistance and to develop vaccines that can either be produced in a shorter production time or can overcome the need for annual matching with the circulating influenza strains. Most importantly for India, as a nation that suffered the highest mortality in the influenza pandemic 1918, there is an urgent need to gear up our existing preparedness for the next pandemic which is capable to hit at any moment in time.
Url:
DOI: 10.1007/s12098-020-03214-1
PubMed: 31811502
PubMed Central: 7091034
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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Influenza</title><author><name sortKey="Dharmapalan, Dhanya" sort="Dharmapalan, Dhanya" uniqKey="Dharmapalan D" first="Dhanya" last="Dharmapalan">Dhanya Dharmapalan</name><affiliation><nlm:aff id="Aff1"></nlm:aff></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">31811502</idno><idno type="pmc">7091034</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7091034</idno><idno type="RBID">PMC:7091034</idno><idno type="doi">10.1007/s12098-020-03214-1</idno><date when="2020">2020</date><idno type="wicri:Area/Pmc/Corpus">000231</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000231</idno><idno type="wicri:Area/Pmc/Curation">000231</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000231</idno><idno type="wicri:Area/Pmc/Checkpoint">000006</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000006</idno><idno type="wicri:Area/Ncbi/Merge">001034</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Influenza</title><author><name sortKey="Dharmapalan, Dhanya" sort="Dharmapalan, Dhanya" uniqKey="Dharmapalan D" first="Dhanya" last="Dharmapalan">Dhanya Dharmapalan</name><affiliation><nlm:aff id="Aff1"></nlm:aff></affiliation></author></analytic><series><title level="j">Indian Journal of Pediatrics</title><idno type="ISSN">0019-5456</idno><idno type="eISSN">0973-7693</idno><imprint><date when="2020">2020</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p id="Par1">Influenza continues to baffle humans by its constantly changing nature. The twenty-first century has witnessed considerable advances in the understanding of the influenza viral pathogenesis, its synergy with bacterial infections and diagnostic methods. However, challenges continue: to find a less expensive and more reliable point-of-care test for use in developing countries, to produce more efficacious antiviral drugs, to explore ways to combat emerging antiviral resistance and to develop vaccines that can either be produced in a shorter production time or can overcome the need for annual matching with the circulating influenza strains. Most importantly for India, as a nation that suffered the highest mortality in the influenza pandemic 1918, there is an urgent need to gear up our existing preparedness for the next pandemic which is capable to hit at any moment in time.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Chandra, S" uniqKey="Chandra S">S Chandra</name></author><author><name sortKey="Eva, K Ne" uniqKey="Eva K">K-NE Eva</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Jester, B" uniqKey="Jester B">B Jester</name></author><author><name sortKey="Uyeki, T" uniqKey="Uyeki T">T Uyeki</name></author><author><name sortKey="Jernigan, D" uniqKey="Jernigan D">D Jernigan</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lowen, Ac" uniqKey="Lowen A">AC Lowen</name></author><author><name sortKey="Steel, J" uniqKey="Steel J">J Steel</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ng, S" uniqKey="Ng S">S Ng</name></author><author><name sortKey="Gordon, A" uniqKey="Gordon A">A Gordon</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Chadha, Ms" uniqKey="Chadha M">MS Chadha</name></author><author><name sortKey="Potdar, Va" uniqKey="Potdar V">VA Potdar</name></author><author><name sortKey="Saha, S" uniqKey="Saha S">S Saha</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bridges, Cb" uniqKey="Bridges C">CB Bridges</name></author><author><name sortKey="Kuehnert, Mj" uniqKey="Kuehnert M">MJ Kuehnert</name></author><author><name sortKey="Hall, Cb" uniqKey="Hall C">CB Hall</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Kumlin, U" uniqKey="Kumlin U">U Kumlin</name></author><author><name sortKey="Olofsson, S" uniqKey="Olofsson S">S Olofsson</name></author><author><name sortKey="Dimock, K" uniqKey="Dimock K">K Dimock</name></author><author><name sortKey="Arnberg, N" uniqKey="Arnberg N">N Arnberg</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mansfield, Keith G" uniqKey="Mansfield K">Keith G. 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<front><journal-meta><journal-id journal-id-type="nlm-ta">Indian J Pediatr</journal-id><journal-id journal-id-type="iso-abbrev">Indian J Pediatr</journal-id><journal-title-group><journal-title>Indian Journal of Pediatrics</journal-title></journal-title-group><issn pub-type="ppub">0019-5456</issn><issn pub-type="epub">0973-7693</issn><publisher><publisher-name>Springer India</publisher-name><publisher-loc>New Delhi</publisher-loc></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">31811502</article-id><article-id pub-id-type="pmc">7091034</article-id><article-id pub-id-type="publisher-id">3214</article-id><article-id pub-id-type="doi">10.1007/s12098-020-03214-1</article-id><article-categories><subj-group subj-group-type="heading"><subject>Review Article</subject></subj-group></article-categories><title-group><article-title>Influenza</article-title></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">http://orcid.org/0000-0002-6691-1435</contrib-id><name><surname>Dharmapalan</surname><given-names>Dhanya</given-names></name><address><email>drdhanyaroshan@gmail.com</email></address><xref ref-type="aff" rid="Aff1"></xref></contrib><aff id="Aff1"><institution-wrap><institution-id institution-id-type="GRID">grid.464529.8</institution-id><institution-id institution-id-type="ISNI">0000 0004 1802 3059</institution-id><institution>Department of Pediatric Infectious Diseases,</institution><institution>Apollo Hospitals,</institution></institution-wrap>CBD Belapur, Navi Mumbai, India</aff></contrib-group><pub-date pub-type="epub"><day>11</day><month>2</month><year>2020</year></pub-date><fpage>1</fpage><lpage>5</lpage><history><date date-type="received"><day>11</day><month>8</month><year>2019</year></date><date date-type="accepted"><day>24</day><month>1</month><year>2020</year></date></history><permissions><copyright-statement>© Dr. K C Chaudhuri Foundation 2020</copyright-statement><license><license-p>This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.</license-p></license></permissions><abstract id="Abs1"><p id="Par1">Influenza continues to baffle humans by its constantly changing nature. The twenty-first century has witnessed considerable advances in the understanding of the influenza viral pathogenesis, its synergy with bacterial infections and diagnostic methods. However, challenges continue: to find a less expensive and more reliable point-of-care test for use in developing countries, to produce more efficacious antiviral drugs, to explore ways to combat emerging antiviral resistance and to develop vaccines that can either be produced in a shorter production time or can overcome the need for annual matching with the circulating influenza strains. Most importantly for India, as a nation that suffered the highest mortality in the influenza pandemic 1918, there is an urgent need to gear up our existing preparedness for the next pandemic which is capable to hit at any moment in time.</p></abstract><kwd-group xml:lang="en"><title>Keywords</title><kwd>Influenza</kwd><kwd>Pandemic</kwd><kwd>Hemagglutinin</kwd><kwd>Neuraminidase</kwd><kwd>Influenza vaccines</kwd><kwd>Oseltamivir</kwd></kwd-group></article-meta></front></pmc><affiliations><list></list><tree><noCountry><name sortKey="Dharmapalan, Dhanya" sort="Dharmapalan, Dhanya" uniqKey="Dharmapalan D" first="Dhanya" last="Dharmapalan">Dhanya Dharmapalan</name></noCountry></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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