Molecular evolution of novel swine-origin A/H1N1 influenza viruses among and before human
Identifieur interne : 000405 ( Ncbi/Merge ); précédent : 000404; suivant : 000406Molecular evolution of novel swine-origin A/H1N1 influenza viruses among and before human
Auteurs : Na Ding ; Nana Wu ; Qinggang Xu ; Keping Chen ; Chiyu ZhangSource :
- Virus Genes [ 0920-8569 ] ; 2009.
Abstract
We find that the novel A/H1N1 influenza viruses exhibit very low genetic divergence and suffer strong purifying selection among human population and confirm that they originated from the reassortment of previous triple-reassortant swine influenza viruses including genomic segments from both avian and human lineages with North American and Eurasian swine lineages. The longer phylogenetic branch length to their nearest genetic neighbors indicates that the origin of the novel A/H1N1 is unlikely to be a very recent event. Seventy-six new unique mutations are found to be monomorphically fixed in the novel A/H1N1 virus lineages, suggesting a role of selective sweep in the early evolution of this virus.
The online version of this article (doi:10.1007/s11262-009-0393-7) contains supplementary material, which is available to authorized users.
Url:
DOI: 10.1007/s11262-009-0393-7
PubMed: 19693661
PubMed Central: 7088527
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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Molecular evolution of novel swine-origin A/H1N1 influenza viruses among and before human</title><author><name sortKey="Ding, Na" sort="Ding, Na" uniqKey="Ding N" first="Na" last="Ding">Na Ding</name><affiliation><nlm:aff id="Aff1"></nlm:aff></affiliation></author><author><name sortKey="Wu, Nana" sort="Wu, Nana" uniqKey="Wu N" first="Nana" last="Wu">Nana Wu</name><affiliation><nlm:aff id="Aff1"></nlm:aff></affiliation></author><author><name sortKey="Xu, Qinggang" sort="Xu, Qinggang" uniqKey="Xu Q" first="Qinggang" last="Xu">Qinggang Xu</name><affiliation><nlm:aff id="Aff1"></nlm:aff></affiliation></author><author><name sortKey="Chen, Keping" sort="Chen, Keping" uniqKey="Chen K" first="Keping" last="Chen">Keping Chen</name><affiliation><nlm:aff id="Aff1"></nlm:aff></affiliation></author><author><name sortKey="Zhang, Chiyu" sort="Zhang, Chiyu" uniqKey="Zhang C" first="Chiyu" last="Zhang">Chiyu Zhang</name><affiliation><nlm:aff id="Aff1"></nlm:aff></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">19693661</idno><idno type="pmc">7088527</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7088527</idno><idno type="RBID">PMC:7088527</idno><idno type="doi">10.1007/s11262-009-0393-7</idno><date when="2009">2009</date><idno type="wicri:Area/Pmc/Corpus">000212</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000212</idno><idno type="wicri:Area/Pmc/Curation">000212</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000212</idno><idno type="wicri:Area/Pmc/Checkpoint">000A26</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000A26</idno><idno type="wicri:Area/Ncbi/Merge">000405</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Molecular evolution of novel swine-origin A/H1N1 influenza viruses among and before human</title><author><name sortKey="Ding, Na" sort="Ding, Na" uniqKey="Ding N" first="Na" last="Ding">Na Ding</name><affiliation><nlm:aff id="Aff1"></nlm:aff></affiliation></author><author><name sortKey="Wu, Nana" sort="Wu, Nana" uniqKey="Wu N" first="Nana" last="Wu">Nana Wu</name><affiliation><nlm:aff id="Aff1"></nlm:aff></affiliation></author><author><name sortKey="Xu, Qinggang" sort="Xu, Qinggang" uniqKey="Xu Q" first="Qinggang" last="Xu">Qinggang Xu</name><affiliation><nlm:aff id="Aff1"></nlm:aff></affiliation></author><author><name sortKey="Chen, Keping" sort="Chen, Keping" uniqKey="Chen K" first="Keping" last="Chen">Keping Chen</name><affiliation><nlm:aff id="Aff1"></nlm:aff></affiliation></author><author><name sortKey="Zhang, Chiyu" sort="Zhang, Chiyu" uniqKey="Zhang C" first="Chiyu" last="Zhang">Chiyu Zhang</name><affiliation><nlm:aff id="Aff1"></nlm:aff></affiliation></author></analytic><series><title level="j">Virus Genes</title><idno type="ISSN">0920-8569</idno><idno type="eISSN">1572-994X</idno><imprint><date when="2009">2009</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>We find that the novel A/H1N1 influenza viruses exhibit very low genetic divergence and suffer strong purifying selection among human population and confirm that they originated from the reassortment of previous triple-reassortant swine influenza viruses including genomic segments from both avian and human lineages with North American and Eurasian swine lineages. The longer phylogenetic branch length to their nearest genetic neighbors indicates that the origin of the novel A/H1N1 is unlikely to be a very recent event. Seventy-six new unique mutations are found to be monomorphically fixed in the novel A/H1N1 virus lineages, suggesting a role of selective sweep in the early evolution of this virus.</p><sec><title>Electronic supplementary material</title><p>The online version of this article (doi:10.1007/s11262-009-0393-7) contains supplementary material, which is available to authorized users.</p></sec></div></front><back><div1 type="bibliography"><listBibl><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Kuiken, T" uniqKey="Kuiken T">T Kuiken</name></author><author><name sortKey="Holmes, Ec" uniqKey="Holmes E">EC Holmes</name></author><author><name sortKey="Mccauley, J" uniqKey="Mccauley J">J McCauley</name></author><author><name sortKey="Rimmelzwaan, Gf" uniqKey="Rimmelzwaan G">GF Rimmelzwaan</name></author><author><name sortKey="Williams, Cs" uniqKey="Williams C">CS Williams</name></author><author><name sortKey="Grenfell, Bt" 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<front><journal-meta><journal-id journal-id-type="nlm-ta">Virus Genes</journal-id><journal-id journal-id-type="iso-abbrev">Virus Genes</journal-id><journal-title-group><journal-title>Virus Genes</journal-title></journal-title-group><issn pub-type="ppub">0920-8569</issn><issn pub-type="epub">1572-994X</issn><publisher><publisher-name>Springer US</publisher-name><publisher-loc>New York</publisher-loc></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">19693661</article-id><article-id pub-id-type="pmc">7088527</article-id><article-id pub-id-type="publisher-id">393</article-id><article-id pub-id-type="doi">10.1007/s11262-009-0393-7</article-id><article-categories><subj-group subj-group-type="heading"><subject>Article</subject></subj-group></article-categories><title-group><article-title>Molecular evolution of novel swine-origin A/H1N1 influenza viruses among and before human</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Ding</surname><given-names>Na</given-names></name><xref ref-type="aff" rid="Aff1"></xref></contrib><contrib contrib-type="author"><name><surname>Wu</surname><given-names>Nana</given-names></name><xref ref-type="aff" rid="Aff1"></xref></contrib><contrib contrib-type="author"><name><surname>Xu</surname><given-names>Qinggang</given-names></name><xref ref-type="aff" rid="Aff1"></xref></contrib><contrib contrib-type="author"><name><surname>Chen</surname><given-names>Keping</given-names></name><xref ref-type="aff" rid="Aff1"></xref></contrib><contrib contrib-type="author" corresp="yes"><name><surname>Zhang</surname><given-names>Chiyu</given-names></name><address><email>zhangcy1999@hotmail.com</email></address><xref ref-type="aff" rid="Aff1"></xref></contrib><aff id="Aff1"><institution-wrap><institution-id institution-id-type="GRID">grid.440785.a</institution-id><institution-id institution-id-type="ISNI">000000010743511X</institution-id><institution>Institute of Life Sciences,</institution><institution>Jiangsu University,</institution></institution-wrap>Zhenjiang, Jiangsu 212013 China</aff></contrib-group><pub-date pub-type="epub"><day>20</day><month>8</month><year>2009</year></pub-date><pub-date pub-type="ppub"><year>2009</year></pub-date><volume>39</volume><issue>3</issue><fpage>293</fpage><lpage>300</lpage><history><date date-type="received"><day>17</day><month>6</month><year>2009</year></date><date date-type="accepted"><day>6</day><month>8</month><year>2009</year></date></history><permissions><copyright-statement>© Springer Science+Business Media, LLC 2009</copyright-statement><license><license-p>This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.</license-p></license></permissions><abstract id="Abs1"><p>We find that the novel A/H1N1 influenza viruses exhibit very low genetic divergence and suffer strong purifying selection among human population and confirm that they originated from the reassortment of previous triple-reassortant swine influenza viruses including genomic segments from both avian and human lineages with North American and Eurasian swine lineages. The longer phylogenetic branch length to their nearest genetic neighbors indicates that the origin of the novel A/H1N1 is unlikely to be a very recent event. Seventy-six new unique mutations are found to be monomorphically fixed in the novel A/H1N1 virus lineages, suggesting a role of selective sweep in the early evolution of this virus.</p><sec><title>Electronic supplementary material</title><p>The online version of this article (doi:10.1007/s11262-009-0393-7) contains supplementary material, which is available to authorized users.</p></sec></abstract><kwd-group xml:lang="en"><title>Keywords</title><kwd>Novel A/H1N1 influenza virus</kwd><kwd>Reassortment</kwd><kwd>Adaptive evolution</kwd><kwd>Selective sweep</kwd></kwd-group><custom-meta-group><custom-meta><meta-name>issue-copyright-statement</meta-name><meta-value>© Springer Science+Business Media, LLC 2009</meta-value></custom-meta></custom-meta-group></article-meta></front></pmc><affiliations><list></list><tree><noCountry><name sortKey="Chen, Keping" sort="Chen, Keping" uniqKey="Chen K" first="Keping" last="Chen">Keping Chen</name><name sortKey="Ding, Na" sort="Ding, Na" uniqKey="Ding N" first="Na" last="Ding">Na Ding</name><name sortKey="Wu, Nana" sort="Wu, Nana" uniqKey="Wu N" first="Nana" last="Wu">Nana Wu</name><name sortKey="Xu, Qinggang" sort="Xu, Qinggang" uniqKey="Xu Q" first="Qinggang" last="Xu">Qinggang Xu</name><name sortKey="Zhang, Chiyu" sort="Zhang, Chiyu" uniqKey="Zhang C" first="Chiyu" last="Zhang">Chiyu Zhang</name></noCountry></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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