The Influenza Virus Enigma
Identifieur interne : 000343 ( Ncbi/Merge ); précédent : 000342; suivant : 000344The Influenza Virus Enigma
Auteurs : Rachelle Salomon [États-Unis] ; Robert G. Webster [États-Unis]Source :
- Cell [ 0092-8674 ] ; 2009.
Abstract
Both seasonal and pandemic influenza continue to challenge both scientists and clinicians. Drug-resistant H1N1 influenza viruses have dominated the 2009 flu season, and the H5N1 avian influenza virus continues to kill both people and poultry in Eurasia. Here, we discuss the pathogenesis and transmissibility of influenza viruses and we emphasize the need to find better predictors of both seasonal and potentially pandemic influenza.
Url:
DOI: 10.1016/j.cell.2009.01.029
PubMed: 19203576
PubMed Central: 2971533
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PMC:2971533Le document en format XML
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<affiliation wicri:level="2"><nlm:aff id="A1">Department of Infectious Diseases, St. Jude Children’s Research Hospital, Memphis, TN 38105-2678, USA</nlm:aff>
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<author><name sortKey="Webster, Robert G" sort="Webster, Robert G" uniqKey="Webster R" first="Robert G." last="Webster">Robert G. Webster</name>
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<front><div type="abstract" xml:lang="en"><p id="P1">Both seasonal and pandemic influenza continue to challenge both scientists and clinicians. Drug-resistant H1N1 influenza viruses have dominated the 2009 flu season, and the H5N1 avian influenza virus continues to kill both people and poultry in Eurasia. Here, we discuss the pathogenesis and transmissibility of influenza viruses and we emphasize the need to find better predictors of both seasonal and potentially pandemic influenza.</p>
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<contrib-group><contrib contrib-type="author"><name><surname>Salomon</surname>
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Department of Infectious Diseases, St. Jude Children’s Research Hospital, Memphis, TN 38105-2678, USA</aff>
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Correspondence: <email>robert.webster@stjude.org</email>
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<pub-date pub-type="nihms-submitted"><day>20</day>
<month>10</month>
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<pub-date pub-type="ppub"><day>6</day>
<month>2</month>
<year>2009</year>
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<pub-date pub-type="pmc-release"><day>3</day>
<month>11</month>
<year>2010</year>
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<volume>136</volume>
<issue>3</issue>
<fpage>402</fpage>
<lpage>410</lpage>
<permissions><copyright-statement>© 2010 Elsevier Inc. All rights reserved.</copyright-statement>
<copyright-year>2010</copyright-year>
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<abstract><p id="P1">Both seasonal and pandemic influenza continue to challenge both scientists and clinicians. Drug-resistant H1N1 influenza viruses have dominated the 2009 flu season, and the H5N1 avian influenza virus continues to kill both people and poultry in Eurasia. Here, we discuss the pathogenesis and transmissibility of influenza viruses and we emphasize the need to find better predictors of both seasonal and potentially pandemic influenza.</p>
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