Sequence of the N2 neuraminidase from influenza virus A/NT/60/68.
Identifieur interne : 001220 ( Ncbi/Curation ); précédent : 001219; suivant : 001221Sequence of the N2 neuraminidase from influenza virus A/NT/60/68.
Auteurs : D R Bentley ; G G BrownleeSource :
- Nucleic Acids Research [ 0305-1048 ] ; 1982.
Abstract
The complete sequence of the neuraminidase gene of influenza virus A/NT/60/68 (N2 subtype) was determined following cloning of full length complementary DNA into pBR322. Comparison of the predicted amino acid sequence with a closely related neuraminidase from A/Udorn/72 suggests that point mutations over an extensive region of the primary sequence can contribute to antigenic drift, although the region between amino acid residues 308 and 371 may be particularly significant.
Url:
PubMed: 6752886
PubMed Central: 320849
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PMC:320849Le document en format XML
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<author><name sortKey="Brownlee, G G" sort="Brownlee, G G" uniqKey="Brownlee G" first="G G" last="Brownlee">G G Brownlee</name>
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<series><title level="j">Nucleic Acids Research</title>
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<front><div type="abstract" xml:lang="en"><p>The complete sequence of the neuraminidase gene of influenza virus A/NT/60/68 (N2 subtype) was determined following cloning of full length complementary DNA into pBR322. Comparison of the predicted amino acid sequence with a closely related neuraminidase from A/Udorn/72 suggests that point mutations over an extensive region of the primary sequence can contribute to antigenic drift, although the region between amino acid residues 308 and 371 may be particularly significant.</p>
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