Glycan-binding preferences and genetic evolution of human seasonal influenza A(H3N2) viruses during 1999-2007 in Taiwan
Identifieur interne : 000E75 ( Ncbi/Curation ); précédent : 000E74; suivant : 000E76Glycan-binding preferences and genetic evolution of human seasonal influenza A(H3N2) viruses during 1999-2007 in Taiwan
Auteurs : Ya-Fang Wang [Taïwan] ; Chuan-Fa Chang [Taïwan] ; Huey-Pin Tsai [Taïwan] ; Chia-Yu Chi [Taïwan] ; Ih-Jen Su [Taïwan] ; Jen-Ren Wang [Taïwan]Source :
- PLoS ONE [ 1932-6203 ] ; 2018.
Abstract
It is generally agreed that human influenza virus preferentially binds to α-2,6-linked sialic acid-containing receptors, and mutations that change the binding preference may alter virus infectivity and host tropism. Limited information is available on the glycan-binding specificity of epidemic influenza viruses. In this study, we systemically investigated the glycan-binding preferences of human influenza A(H3N2) viruses isolated from 1999 to 2007 in Taiwan using a high-throughput carbohydrate array. The binding patterns of 37 H3N2 viruses were classified into three groups with significant binding-pattern variations. The results showed that the carbohydrate-binding patterns of H3N2 varied over time. A phylogenetic analysis of the hemagglutinin gene also revealed progressive drift year to year. Of note, the viruses that caused large outbreaks in 1999 and 2003 showed glycan-binding preferences to both α-2,3 and α-2,6 sialylated glycans. Twenty amino acid substitutions were identified primarily at antigenic sites that might contribute to H3N2 virus evolution and the change in the glycan-binding patterns. This study provides not only a systematic analysis of the receptor-binding specificity of influenza clinical isolates but also information that could help to monitor the outbreak potential and virus evolution of influenza viruses.
Url:
DOI: 10.1371/journal.pone.0196727
PubMed: 29746492
PubMed Central: 5945028
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<front><div type="abstract" xml:lang="en"><p>It is generally agreed that human influenza virus preferentially binds to α-2,6-linked sialic acid-containing receptors, and mutations that change the binding preference may alter virus infectivity and host tropism. Limited information is available on the glycan-binding specificity of epidemic influenza viruses. In this study, we systemically investigated the glycan-binding preferences of human influenza A(H3N2) viruses isolated from 1999 to 2007 in Taiwan using a high-throughput carbohydrate array. The binding patterns of 37 H3N2 viruses were classified into three groups with significant binding-pattern variations. The results showed that the carbohydrate-binding patterns of H3N2 varied over time. A phylogenetic analysis of the hemagglutinin gene also revealed progressive drift year to year. Of note, the viruses that caused large outbreaks in 1999 and 2003 showed glycan-binding preferences to both α-2,3 and α-2,6 sialylated glycans. Twenty amino acid substitutions were identified primarily at antigenic sites that might contribute to H3N2 virus evolution and the change in the glycan-binding patterns. This study provides not only a systematic analysis of the receptor-binding specificity of influenza clinical isolates but also information that could help to monitor the outbreak potential and virus evolution of influenza viruses.</p>
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<back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Kobayashi, Y" uniqKey="Kobayashi Y">Y Kobayashi</name>
</author>
<author><name sortKey="Suzuki, Y" uniqKey="Suzuki Y">Y Suzuki</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Viswanathan, K" uniqKey="Viswanathan K">K Viswanathan</name>
</author>
<author><name sortKey="Koh, X" uniqKey="Koh X">X Koh</name>
</author>
<author><name sortKey="Chandrasekaran, A" uniqKey="Chandrasekaran A">A Chandrasekaran</name>
</author>
<author><name sortKey="Pappas, C" uniqKey="Pappas C">C Pappas</name>
</author>
<author><name sortKey="Raman, R" uniqKey="Raman R">R Raman</name>
</author>
<author><name sortKey="Srinivasan, A" uniqKey="Srinivasan A">A Srinivasan</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Wilks, S" uniqKey="Wilks S">S Wilks</name>
</author>
<author><name sortKey="De Graaf, M" uniqKey="De Graaf M">M de Graaf</name>
</author>
<author><name sortKey="Smith, Dj" uniqKey="Smith D">DJ Smith</name>
</author>
<author><name sortKey="Burke, Df" uniqKey="Burke D">DF Burke</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Skehel, Jj" uniqKey="Skehel J">JJ Skehel</name>
</author>
<author><name sortKey="Wiley, Dc" uniqKey="Wiley D">DC Wiley</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Kyoko Shinya, Me" uniqKey="Kyoko Shinya M">ME Kyoko Shinya</name>
</author>
<author><name sortKey="Yamada, Shinya" uniqKey="Yamada S">Shinya Yamada</name>
</author>
<author><name sortKey="Ono, Masao" uniqKey="Ono M">Masao Ono</name>
</author>
<author><name sortKey="Kasai, Noriyuki" uniqKey="Kasai N">Noriyuki Kasai</name>
</author>
<author><name sortKey="Kawaoka, Yoshihiro" uniqKey="Kawaoka Y">Yoshihiro Kawaoka</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Viswanathan, K" uniqKey="Viswanathan K">K Viswanathan</name>
</author>
<author><name sortKey="Chandrasekaran, A" uniqKey="Chandrasekaran A">A Chandrasekaran</name>
</author>
<author><name sortKey="Srinivasan, A" uniqKey="Srinivasan A">A Srinivasan</name>
</author>
<author><name sortKey="Raman, R" uniqKey="Raman R">R Raman</name>
</author>
<author><name sortKey="Sasisekharan, V" uniqKey="Sasisekharan V">V Sasisekharan</name>
</author>
<author><name sortKey="Sasisekharan, R" uniqKey="Sasisekharan R">R Sasisekharan</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Tumpey, Tm" uniqKey="Tumpey T">TM Tumpey</name>
</author>
<author><name sortKey="Maines, Tr" uniqKey="Maines T">TR Maines</name>
</author>
<author><name sortKey="Van Hoeven, N" uniqKey="Van Hoeven N">N Van Hoeven</name>
</author>
<author><name sortKey="Glaser, L" uniqKey="Glaser L">L Glaser</name>
</author>
<author><name sortKey="Solorzano, A" uniqKey="Solorzano A">A Solorzano</name>
</author>
<author><name sortKey="Pappas, C" uniqKey="Pappas C">C Pappas</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Stevens, J" uniqKey="Stevens J">J Stevens</name>
</author>
<author><name sortKey="Blixt, O" uniqKey="Blixt O">O Blixt</name>
</author>
<author><name sortKey="Tumpey, Tm" uniqKey="Tumpey T">TM Tumpey</name>
</author>
<author><name sortKey="Taubenberger, Jk" uniqKey="Taubenberger J">JK Taubenberger</name>
</author>
<author><name sortKey="Paulson, Jc" uniqKey="Paulson J">JC Paulson</name>
</author>
<author><name sortKey="Wilson, Ia" uniqKey="Wilson I">IA Wilson</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Stevens, J" uniqKey="Stevens J">J Stevens</name>
</author>
<author><name sortKey="Blixt, O" uniqKey="Blixt O">O Blixt</name>
</author>
<author><name sortKey="Chen, Lm" uniqKey="Chen L">LM Chen</name>
</author>
<author><name sortKey="Donis, Ro" uniqKey="Donis R">RO Donis</name>
</author>
<author><name sortKey="Paulson, Jc" uniqKey="Paulson J">JC Paulson</name>
</author>
<author><name sortKey="Wilson, Ia" uniqKey="Wilson I">IA Wilson</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Kumari, K" uniqKey="Kumari K">K Kumari</name>
</author>
<author><name sortKey="Gulati, S" uniqKey="Gulati S">S Gulati</name>
</author>
<author><name sortKey="Smith, Df" uniqKey="Smith D">DF Smith</name>
</author>
<author><name sortKey="Gulati, U" uniqKey="Gulati U">U Gulati</name>
</author>
<author><name sortKey="Cummings, Rd" uniqKey="Cummings R">RD Cummings</name>
</author>
<author><name sortKey="Air, Gm" uniqKey="Air G">GM Air</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Gulati, S" uniqKey="Gulati S">S Gulati</name>
</author>
<author><name sortKey="Smith, Df" uniqKey="Smith D">DF Smith</name>
</author>
<author><name sortKey="Air, Gm" uniqKey="Air G">GM Air</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Gulati, S" uniqKey="Gulati S">S Gulati</name>
</author>
<author><name sortKey="Smith, Df" uniqKey="Smith D">DF Smith</name>
</author>
<author><name sortKey="Cummings, Rd" uniqKey="Cummings R">RD Cummings</name>
</author>
<author><name sortKey="Couch, Rb" uniqKey="Couch R">RB Couch</name>
</author>
<author><name sortKey="Griesemer, Sb" uniqKey="Griesemer S">SB Griesemer</name>
</author>
<author><name sortKey="St George, K" uniqKey="St George K">K St George</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Wang, Yf" uniqKey="Wang Y">YF Wang</name>
</author>
<author><name sortKey="Chang, Cf" uniqKey="Chang C">CF Chang</name>
</author>
<author><name sortKey="Chi, Cy" uniqKey="Chi C">CY Chi</name>
</author>
<author><name sortKey="Wang, Hc" uniqKey="Wang H">HC Wang</name>
</author>
<author><name sortKey="Wang, Jr" uniqKey="Wang J">JR Wang</name>
</author>
<author><name sortKey="Su, Ij" uniqKey="Su I">IJ Su</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Tsai, Hp" uniqKey="Tsai H">HP Tsai</name>
</author>
<author><name sortKey="Wang, Hc" uniqKey="Wang H">HC Wang</name>
</author>
<author><name sortKey="Kiang, D" uniqKey="Kiang D">D Kiang</name>
</author>
<author><name sortKey="Huang, Sw" uniqKey="Huang S">SW Huang</name>
</author>
<author><name sortKey="Kuo, Ph" uniqKey="Kuo P">PH Kuo</name>
</author>
<author><name sortKey="Liu, Cc" uniqKey="Liu C">CC Liu</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Goldstein, Ma" uniqKey="Goldstein M">MA Goldstein</name>
</author>
<author><name sortKey="Tauraso, Nm" uniqKey="Tauraso N">NM Tauraso</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Chang, Cf" uniqKey="Chang C">CF Chang</name>
</author>
<author><name sortKey="Pan, Jf" uniqKey="Pan J">JF Pan</name>
</author>
<author><name sortKey="Lin, Cn" uniqKey="Lin C">CN Lin</name>
</author>
<author><name sortKey="Wu, Il" uniqKey="Wu I">IL Wu</name>
</author>
<author><name sortKey="Wong, Ch" uniqKey="Wong C">CH Wong</name>
</author>
<author><name sortKey="Lin, Ch" uniqKey="Lin C">CH Lin</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Wang, Sf" uniqKey="Wang S">SF Wang</name>
</author>
<author><name sortKey="Lee, Ym" uniqKey="Lee Y">YM Lee</name>
</author>
<author><name sortKey="Chan, Yj" uniqKey="Chan Y">YJ Chan</name>
</author>
<author><name sortKey="Liu, Hf" uniqKey="Liu H">HF Liu</name>
</author>
<author><name sortKey="Yen, Yf" uniqKey="Yen Y">YF Yen</name>
</author>
<author><name sortKey="Liu, Wt" uniqKey="Liu W">WT Liu</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Rogers, Gn" uniqKey="Rogers G">GN Rogers</name>
</author>
<author><name sortKey="Paulson, Jc" uniqKey="Paulson J">JC Paulson</name>
</author>
<author><name sortKey="Daniels, Rs" uniqKey="Daniels R">RS Daniels</name>
</author>
<author><name sortKey="Skehel, Jj" uniqKey="Skehel J">JJ Skehel</name>
</author>
<author><name sortKey="Wilson, Ia" uniqKey="Wilson I">IA Wilson</name>
</author>
<author><name sortKey="Wiley, Dc" uniqKey="Wiley D">DC Wiley</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Lin, Yp" uniqKey="Lin Y">YP Lin</name>
</author>
<author><name sortKey="Xiong, X" uniqKey="Xiong X">X Xiong</name>
</author>
<author><name sortKey="Wharton, Sa" uniqKey="Wharton S">SA Wharton</name>
</author>
<author><name sortKey="Martin, Sr" uniqKey="Martin S">SR Martin</name>
</author>
<author><name sortKey="Coombs, Pj" uniqKey="Coombs P">PJ Coombs</name>
</author>
<author><name sortKey="Vachieri, Sg" uniqKey="Vachieri S">SG Vachieri</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Stohr, K" uniqKey="Stohr K">K Stohr</name>
</author>
</analytic>
</biblStruct>
<biblStruct></biblStruct>
<biblStruct><analytic><author><name sortKey="Akazawa, M" uniqKey="Akazawa M">M Akazawa</name>
</author>
<author><name sortKey="Sindelar, Jl" uniqKey="Sindelar J">JL Sindelar</name>
</author>
<author><name sortKey="Paltiel, Ad" uniqKey="Paltiel A">AD Paltiel</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Rambaut, A" uniqKey="Rambaut A">A Rambaut</name>
</author>
<author><name sortKey="Pybus, Og" uniqKey="Pybus O">OG Pybus</name>
</author>
<author><name sortKey="Nelson, Mi" uniqKey="Nelson M">MI Nelson</name>
</author>
<author><name sortKey="Viboud, C" uniqKey="Viboud C">C Viboud</name>
</author>
<author><name sortKey="Taubenberger, Jk" uniqKey="Taubenberger J">JK Taubenberger</name>
</author>
<author><name sortKey="Holmes, Ec" uniqKey="Holmes E">EC Holmes</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Meisen, I" uniqKey="Meisen I">I Meisen</name>
</author>
<author><name sortKey="Dzudzek, T" uniqKey="Dzudzek T">T Dzudzek</name>
</author>
<author><name sortKey="Ehrhardt, C" uniqKey="Ehrhardt C">C Ehrhardt</name>
</author>
<author><name sortKey="Ludwig, S" uniqKey="Ludwig S">S Ludwig</name>
</author>
<author><name sortKey="Mormann, M" uniqKey="Mormann M">M Mormann</name>
</author>
<author><name sortKey="Rosenbruck, R" uniqKey="Rosenbruck R">R Rosenbruck</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Stevens, J" uniqKey="Stevens J">J Stevens</name>
</author>
<author><name sortKey="Chen, Lm" uniqKey="Chen L">LM Chen</name>
</author>
<author><name sortKey="Carney, Pj" uniqKey="Carney P">PJ Carney</name>
</author>
<author><name sortKey="Garten, R" uniqKey="Garten R">R Garten</name>
</author>
<author><name sortKey="Foust, A" uniqKey="Foust A">A Foust</name>
</author>
<author><name sortKey="Le, J" uniqKey="Le J">J Le</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Medeiros, R" uniqKey="Medeiros R">R Medeiros</name>
</author>
<author><name sortKey="Escriou, N" uniqKey="Escriou N">N Escriou</name>
</author>
<author><name sortKey="Naffakh, N" uniqKey="Naffakh N">N Naffakh</name>
</author>
<author><name sortKey="Manuguerra, Jc" uniqKey="Manuguerra J">JC Manuguerra</name>
</author>
<author><name sortKey="Van Der Werf, S" uniqKey="Van Der Werf S">S van der Werf</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Asaoka, N" uniqKey="Asaoka N">N Asaoka</name>
</author>
<author><name sortKey="Tanaka, Y" uniqKey="Tanaka Y">Y Tanaka</name>
</author>
<author><name sortKey="Sakai, T" uniqKey="Sakai T">T Sakai</name>
</author>
<author><name sortKey="Fujii, Y" uniqKey="Fujii Y">Y Fujii</name>
</author>
<author><name sortKey="Ohuchi, R" uniqKey="Ohuchi R">R Ohuchi</name>
</author>
<author><name sortKey="Ohuchi, M" uniqKey="Ohuchi M">M Ohuchi</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Air, Gm" uniqKey="Air G">GM Air</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Chandrasekaran, A" uniqKey="Chandrasekaran A">A Chandrasekaran</name>
</author>
<author><name sortKey="Srinivasan, A" uniqKey="Srinivasan A">A Srinivasan</name>
</author>
<author><name sortKey="Raman, R" uniqKey="Raman R">R Raman</name>
</author>
<author><name sortKey="Viswanathan, K" uniqKey="Viswanathan K">K Viswanathan</name>
</author>
<author><name sortKey="Raguram, S" uniqKey="Raguram S">S Raguram</name>
</author>
<author><name sortKey="Tumpey, Tm" uniqKey="Tumpey T">TM Tumpey</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Webster, Rg" uniqKey="Webster R">RG Webster</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Desselberger, U" uniqKey="Desselberger U">U Desselberger</name>
</author>
<author><name sortKey="Nakajima, K" uniqKey="Nakajima K">K Nakajima</name>
</author>
<author><name sortKey="Alfino, P" uniqKey="Alfino P">P Alfino</name>
</author>
<author><name sortKey="Pedersen, Fs" uniqKey="Pedersen F">FS Pedersen</name>
</author>
<author><name sortKey="Haseltine, Wa" uniqKey="Haseltine W">WA Haseltine</name>
</author>
<author><name sortKey="Hannoun, C" uniqKey="Hannoun C">C Hannoun</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Schild, Gc" uniqKey="Schild G">GC Schild</name>
</author>
<author><name sortKey="Oxford, Js" uniqKey="Oxford J">JS Oxford</name>
</author>
<author><name sortKey="Dowdle, Wr" uniqKey="Dowdle W">WR Dowdle</name>
</author>
<author><name sortKey="Coleman, M" uniqKey="Coleman M">M Coleman</name>
</author>
<author><name sortKey="Pereira, Ms" uniqKey="Pereira M">MS Pereira</name>
</author>
<author><name sortKey="Chakraverty, P" uniqKey="Chakraverty P">P Chakraverty</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Stray, Sj" uniqKey="Stray S">SJ Stray</name>
</author>
<author><name sortKey="Pittman, Lb" uniqKey="Pittman L">LB Pittman</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Webster, Rg" uniqKey="Webster R">RG Webster</name>
</author>
</analytic>
</biblStruct>
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