Phylogenetic analysis and pathogenicity of H3 subtype avian influenza viruses isolated from live poultry markets in China
Identifieur interne : 000C86 ( Ncbi/Checkpoint ); précédent : 000C85; suivant : 000C87Phylogenetic analysis and pathogenicity of H3 subtype avian influenza viruses isolated from live poultry markets in China
Auteurs : Hongrui Cui [République populaire de Chine] ; Ying Shi [République populaire de Chine] ; Tao Ruan [République populaire de Chine] ; Xuesong Li [République populaire de Chine] ; Qiaoyang Teng [République populaire de Chine] ; Hongjun Chen [République populaire de Chine] ; Jianmei Yang [République populaire de Chine] ; Qinfang Liu [République populaire de Chine] ; Zejun Li [République populaire de Chine]Source :
- Scientific Reports [ 2045-2322 ] ; 2016.
Abstract
H3 subtype influenza A virus is one of the main subtypes that threats both public and animal health. However, the evolution and pathogenicity of H3 avian influenza virus (AIV) circulating in domestic birds in China remain largely unclear. In this study, seven H3 AIVs (four H3N2 and three H3N8) were isolated from poultry in live poultry market (LPM) in China. Phylogenetic analyses of full genomes showed that all viruses were clustered into Eurasian lineage, except N8 genes of two H3N8 isolates fell into North American lineage. Intriguingly, the N8 gene of one H3N8 and PB2, PB1, NP and NS of two H3N2 isolates have close relationship with those of the highly pathogenic H5N8 viruses circulating in Korea and United States, suggesting that the H3-like AIV may contribute internal genes to the highly pathogenic H5N8 viruses. Phylogenetic tree of HA gene and antigenic cross-reactivity results indicated that two antigenically different H3 viruses are circulating in LPM in China. Most of the H3 viruses replicated in mice lung and nasal turbinate without prior adaptation, and the representative H3 viruses infected chickens without causing clinical signs. The reassortment of H3 subtype influenza viruses warrants continuous surveillance in LPM in China.
Url:
DOI: 10.1038/srep27360
PubMed: 27270298
PubMed Central: 4895239
Affiliations:
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China</country></nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Ruan, Tao" sort="Ruan, Tao" uniqKey="Ruan T" first="Tao" last="Ruan">Tao Ruan</name><affiliation wicri:level="1"><nlm:aff id="a1"><institution>Shanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences</institution>, Shanghai,<country>People’s Republic of China</country></nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Li, Xuesong" sort="Li, Xuesong" uniqKey="Li X" first="Xuesong" last="Li">Xuesong Li</name><affiliation wicri:level="1"><nlm:aff id="a1"><institution>Shanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences</institution>, Shanghai,<country>People’s Republic of China</country></nlm:aff><country 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Sciences</institution>, Shanghai,<country>People’s Republic of China</country></nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Shi, Ying" sort="Shi, Ying" uniqKey="Shi Y" first="Ying" last="Shi">Ying Shi</name><affiliation wicri:level="1"><nlm:aff id="a1"><institution>Shanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences</institution>, Shanghai,<country>People’s Republic of China</country></nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Ruan, Tao" sort="Ruan, Tao" uniqKey="Ruan T" first="Tao" last="Ruan">Tao Ruan</name><affiliation wicri:level="1"><nlm:aff id="a1"><institution>Shanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences</institution>, Shanghai,<country>People’s Republic of China</country></nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Li, Xuesong" sort="Li, Xuesong" uniqKey="Li X" first="Xuesong" last="Li">Xuesong Li</name><affiliation wicri:level="1"><nlm:aff id="a1"><institution>Shanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences</institution>, Shanghai,<country>People’s Republic of China</country></nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Teng, Qiaoyang" sort="Teng, Qiaoyang" uniqKey="Teng Q" first="Qiaoyang" last="Teng">Qiaoyang Teng</name><affiliation wicri:level="1"><nlm:aff id="a1"><institution>Shanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences</institution>, Shanghai,<country>People’s Republic of China</country></nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Chen, Hongjun" sort="Chen, Hongjun" uniqKey="Chen H" first="Hongjun" last="Chen">Hongjun Chen</name><affiliation wicri:level="1"><nlm:aff id="a1"><institution>Shanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences</institution>, Shanghai,<country>People’s Republic of China</country></nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Yang, Jianmei" sort="Yang, Jianmei" uniqKey="Yang J" first="Jianmei" last="Yang">Jianmei Yang</name><affiliation wicri:level="1"><nlm:aff id="a1"><institution>Shanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences</institution>, Shanghai,<country>People’s Republic of China</country></nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Liu, Qinfang" sort="Liu, Qinfang" uniqKey="Liu Q" first="Qinfang" last="Liu">Qinfang Liu</name><affiliation wicri:level="1"><nlm:aff id="a1"><institution>Shanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences</institution>, Shanghai,<country>People’s Republic of China</country></nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Li, Zejun" sort="Li, Zejun" uniqKey="Li Z" first="Zejun" last="Li">Zejun Li</name><affiliation wicri:level="1"><nlm:aff id="a1"><institution>Shanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences</institution>, Shanghai,<country>People’s Republic of China</country></nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author></analytic><series><title level="j">Scientific Reports</title><idno type="eISSN">2045-2322</idno><imprint><date when="2016">2016</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>H3 subtype influenza A virus is one of the main subtypes that threats both public and animal health. However, the evolution and pathogenicity of H3 avian influenza virus (AIV) circulating in domestic birds in China remain largely unclear. In this study, seven H3 AIVs (four H3N2 and three H3N8) were isolated from poultry in live poultry market (LPM) in China. Phylogenetic analyses of full genomes showed that all viruses were clustered into Eurasian lineage, except N8 genes of two H3N8 isolates fell into North American lineage. Intriguingly, the N8 gene of one H3N8 and PB2, PB1, NP and NS of two H3N2 isolates have close relationship with those of the highly pathogenic H5N8 viruses circulating in Korea and United States, suggesting that the H3-like AIV may contribute internal genes to the highly pathogenic H5N8 viruses. Phylogenetic tree of HA gene and antigenic cross-reactivity results indicated that two antigenically different H3 viruses are circulating in LPM in China. Most of the H3 viruses replicated in mice lung and nasal turbinate without prior adaptation, and the representative H3 viruses infected chickens without causing clinical signs. The reassortment of H3 subtype influenza viruses warrants continuous surveillance in LPM in China.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Webster, R G" uniqKey="Webster R">R. G. Webster</name></author><author><name sortKey="Bean, W J" uniqKey="Bean W">W. J. Bean</name></author><author><name sortKey="Gorman, O T" uniqKey="Gorman O">O. T. Gorman</name></author><author><name sortKey="Chambers, T M" uniqKey="Chambers T">T. M. Chambers</name></author><author><name sortKey="Kawaoka, Y" uniqKey="Kawaoka Y">Y. Kawaoka</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Garten, R J" uniqKey="Garten R">R. J. Garten</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Pappas, C" uniqKey="Pappas C">C. Pappas</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Scholtissek, C" uniqKey="Scholtissek C">C. Scholtissek</name></author><author><name sortKey="Rohde, W V" uniqKey="Rohde W">W. v. Rohde</name></author><author><name sortKey="Von Hoyningen, V" uniqKey="Von Hoyningen V">V. Von Hoyningen</name></author><author><name sortKey="Rott, R" uniqKey="Rott R">R. Rott</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Yang, D" uniqKey="Yang D">D. Yang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Tong, S" uniqKey="Tong S">S. Tong</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wu, Y" uniqKey="Wu Y">Y. Wu</name></author><author><name sortKey="Wu, Y" uniqKey="Wu Y">Y. Wu</name></author><author><name sortKey="Tefsen, B" uniqKey="Tefsen B">B. Tefsen</name></author><author><name sortKey="Shi, Y" uniqKey="Shi Y">Y. Shi</name></author><author><name sortKey="Gao, G F" uniqKey="Gao G">G. F. Gao</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Morens, D M" uniqKey="Morens D">D. M. Morens</name></author><author><name sortKey="Taubenberger, J K" uniqKey="Taubenberger J">J. K. Taubenberger</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Taubenberger, J K" uniqKey="Taubenberger J">J. K. Taubenberger</name></author><author><name sortKey="Kash, J C" uniqKey="Kash J">J. C. Kash</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bean, W" uniqKey="Bean W">W. Bean</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Yoon, S W" uniqKey="Yoon S">S.-W. Yoon</name></author><author><name sortKey="Webby, R J" uniqKey="Webby R">R. J. Webby</name></author><author><name sortKey="Webster, R G" uniqKey="Webster R">R. G. Webster</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Song, M S" uniqKey="Song M">M.-S. Song</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Pu, J" uniqKey="Pu J">J. Pu</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Zhou, H" uniqKey="Zhou H">H. Zhou</name></author><author><name sortKey="Zhang, A" uniqKey="Zhang A">A. Zhang</name></author><author><name sortKey="Chen, H" uniqKey="Chen H">H. Chen</name></author><author><name sortKey="Jin, M" uniqKey="Jin M">M. Jin</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Song, D" uniqKey="Song D">D. Song</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Castrucci, M R" uniqKey="Castrucci M">M. R. Castrucci</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kahn, R E" uniqKey="Kahn R">R. E. Kahn</name></author><author><name sortKey="Ma, W" uniqKey="Ma W">W. Ma</name></author><author><name sortKey="Richt, J A" uniqKey="Richt J">J. A. Richt</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Li, S" uniqKey="Li S">S. Li</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Song, D" uniqKey="Song D">D. Song</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bean, W J" uniqKey="Bean W">W. J. Bean</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Waddell, G H" uniqKey="Waddell G">G. H. Waddell</name></author><author><name sortKey="Teigland, M B" uniqKey="Teigland M">M. B. Teigland</name></author><author><name sortKey="Sigel, M M" uniqKey="Sigel M">M. M. Sigel</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Guo, Y" uniqKey="Guo Y">Y. Guo</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Crawford, P C" uniqKey="Crawford P">P. C. Crawford</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Anthony, S J" uniqKey="Anthony S">S. J. Anthony</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Li, C" uniqKey="Li C">C. Li</name></author><author><name sortKey="Yu, M" uniqKey="Yu M">M. Yu</name></author><author><name sortKey="Liu, L" uniqKey="Liu L">L. Liu</name></author><author><name sortKey="Sun, H" uniqKey="Sun H">H. Sun</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Yu, H" uniqKey="Yu H">H. Yu</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Gilbert, M" uniqKey="Gilbert M">M. Gilbert</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wu, D" uniqKey="Wu D">D. Wu</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wang, Y" uniqKey="Wang Y">Y. Wang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Teng, Q" uniqKey="Teng Q">Q. Teng</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hoffmann, E" uniqKey="Hoffmann E">E. Hoffmann</name></author><author><name sortKey="Stech, J" uniqKey="Stech J">J. Stech</name></author><author><name sortKey="Guan, Y" uniqKey="Guan Y">Y. Guan</name></author><author><name sortKey="Webster, R" uniqKey="Webster R">R. Webster</name></author><author><name sortKey="Perez, D" uniqKey="Perez D">D. Perez</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Tamura, K" uniqKey="Tamura K">K. Tamura</name></author><author><name sortKey="Stecher, G" uniqKey="Stecher G">G. Stecher</name></author><author><name sortKey="Peterson, D" uniqKey="Peterson D">D. Peterson</name></author><author><name sortKey="Filipski, A" uniqKey="Filipski A">A. Filipski</name></author><author><name sortKey="Kumar, S" uniqKey="Kumar S">S. Kumar</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Reed, L J" uniqKey="Reed L">L. J. Reed</name></author><author><name sortKey="Muench, H" uniqKey="Muench H">H. Muench</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Klimov, A" uniqKey="Klimov A">A. Klimov</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Min Suk, S" uniqKey="Min Suk S">S. Min-Suk</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Liu, Q" uniqKey="Liu Q">Q. Liu</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Andreas, L B" uniqKey="Andreas L">L. B. Andreas</name></author><author><name sortKey="Eddy, M T" uniqKey="Eddy M">M. T. Eddy</name></author><author><name sortKey="Chou, J J" uniqKey="Chou J">J. J. Chou</name></author><author><name sortKey="Griffin, R G" uniqKey="Griffin R">R. G. Griffin</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Liu, M" uniqKey="Liu M">M. Liu</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Choi, J G" uniqKey="Choi J">J. G. Choi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Song, D" uniqKey="Song D">D. Song</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Crispe, E" uniqKey="Crispe E">E. Crispe</name></author><author><name sortKey="Finlaison, D S" uniqKey="Finlaison D">D. S. Finlaison</name></author><author><name sortKey="Hurt, A C" uniqKey="Hurt A">A. C. Hurt</name></author><author><name sortKey="Kirkland, P D" uniqKey="Kirkland P">P. D. Kirkland</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Su, S" uniqKey="Su S">S. Su</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Cappuccio, J A" uniqKey="Cappuccio J">J. A. Cappuccio</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Rajao, D S" uniqKey="Rajao D">D. S. Rajao</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Liang, L" uniqKey="Liang L">L. Liang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Obenauer, J C" uniqKey="Obenauer J">J. C. Obenauer</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hall, J S" uniqKey="Hall J">J. S. Hall</name></author><author><name sortKey="Dusek, R J" uniqKey="Dusek R">R. J. Dusek</name></author><author><name sortKey="Spackman, E" uniqKey="Spackman E">E. Spackman</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kang, H M" uniqKey="Kang H">H. M. Kang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Zhao, K" uniqKey="Zhao K">K. Zhao</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Pulit Penaloza, J A" uniqKey="Pulit Penaloza J">J. A. Pulit-Penaloza</name></author></analytic></biblStruct></listBibl></div1></back></TEI><affiliations><list><country><li>République populaire de Chine</li></country></list><tree><country name="République populaire de Chine"><noRegion><name sortKey="Cui, Hongrui" sort="Cui, Hongrui" uniqKey="Cui H" first="Hongrui" last="Cui">Hongrui Cui</name></noRegion><name sortKey="Chen, Hongjun" sort="Chen, Hongjun" uniqKey="Chen H" first="Hongjun" last="Chen">Hongjun Chen</name><name sortKey="Li, Xuesong" sort="Li, Xuesong" uniqKey="Li X" first="Xuesong" last="Li">Xuesong Li</name><name sortKey="Li, Zejun" sort="Li, Zejun" uniqKey="Li Z" first="Zejun" last="Li">Zejun Li</name><name sortKey="Liu, Qinfang" sort="Liu, Qinfang" uniqKey="Liu Q" first="Qinfang" last="Liu">Qinfang Liu</name><name sortKey="Ruan, Tao" sort="Ruan, Tao" uniqKey="Ruan T" first="Tao" last="Ruan">Tao Ruan</name><name sortKey="Shi, Ying" sort="Shi, Ying" uniqKey="Shi Y" first="Ying" last="Shi">Ying Shi</name><name sortKey="Teng, Qiaoyang" sort="Teng, Qiaoyang" uniqKey="Teng Q" first="Qiaoyang" last="Teng">Qiaoyang Teng</name><name sortKey="Yang, Jianmei" sort="Yang, Jianmei" uniqKey="Yang J" first="Jianmei" last="Yang">Jianmei Yang</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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|area= H2N2V1
|flux= Ncbi
|étape= Checkpoint
|type= RBID
|clé= PMC:4895239
|texte= Phylogenetic analysis and pathogenicity of H3 subtype avian influenza viruses isolated from live poultry markets in China
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Ncbi/Checkpoint/RBID.i -Sk "pubmed:27270298" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Ncbi/Checkpoint/biblio.hfd \
| NlmPubMed2Wicri -a H2N2V1
| This area was generated with Dilib version V0.6.33. |  |