IPMiner: a progenitor gene identifier for influenza A virus
Identifieur interne : 000668 ( Ncbi/Checkpoint ); précédent : 000667; suivant : 000669IPMiner: a progenitor gene identifier for influenza A virus
Auteurs : Zhipeng Cai [États-Unis] ; Yueming Duan [États-Unis] ; Yingshu Li [États-Unis] ; Guohui Lin [Canada] ; Mufit Ozden [États-Unis] ; Xiu-Feng Wan [États-Unis]Source :
- Influenza and other respiratory viruses [ 1750-2640 ] ; 2011.
Abstract
Identification of the genetic origin of influenza A viruses will facilitate understanding of the genomic dynamics, evolutionary pathway, and viral fitness of influenza A viruses. The exponential increases of influenza sequences have expanded the coverage of influenza genetic pool, thus potentially reducing the biases for influenza progenitor identification. However, these large amounts of data generate a great challenge in progenitor identification. To increase computational efficiency, IPMiner is developed by integrating complete composition vector for genetic distance calculation and minimum spanning tree algorithm for progenitor identification. IPMiner is available to at
Url:
PubMed: 21761594
PubMed Central: 3208347
Affiliations:
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PMC:3208347Le document en format XML
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<series><title level="j">Influenza and other respiratory viruses</title>
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<front><div type="abstract" xml:lang="en"><p id="P1">Identification of the genetic origin of influenza A viruses will facilitate understanding of the genomic dynamics, evolutionary pathway, and viral fitness of influenza A viruses. The exponential increases of influenza sequences have expanded the coverage of influenza genetic pool, thus potentially reducing the biases for influenza progenitor identification. However, these large amounts of data generate a great challenge in progenitor identification. To increase computational efficiency, IPMiner is developed by integrating complete composition vector for genetic distance calculation and minimum spanning tree algorithm for progenitor identification. IPMiner is available to at <ext-link ext-link-type="uri" xlink:href="http://sysbio.cvm.msstate.edu/IPMiner">http://sysbio.cvm.msstate.edu/IPMiner</ext-link>
.</p>
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