The recognition of a viral antigenic moiety by class I MHC-restricted cytolytic T lymphocytes is limited by the availability of the endogenously processed antigen
Identifieur interne : 002231 ( Main/Merge ); précédent : 002230; suivant : 002232The recognition of a viral antigenic moiety by class I MHC-restricted cytolytic T lymphocytes is limited by the availability of the endogenously processed antigen
Auteurs : G. N. Milligan [États-Unis] ; L. A. Morrison [États-Unis] ; J. Gorka ; V. L. Braciale [États-Unis] ; T. J. Braciale [États-Unis]Source :
- (The) Journal of immunology : (Baltimore, MD. 1950) [ 0022-1767 ] ; 1990.
Descripteurs français
- Pascal (Inist)
English descriptors
- KwdEn :
Abstract
The transmembrane hydrophobic domain of the type A influenza A/JAPAN/305/57 (H2N2) hemagglutinin (HA) contains an immunodominant site encompassing amino acids 523-545 (J523-545) recognized by class I MHC-restricted cytolytic T lymphocytes (CTL). Class I CTL of two fine specificity subsets map to this transmembrane (TM) site. One of these CTL subpopulations is subtype specific
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Pascal:92-0658912Le document en format XML
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Antigen presentation</term>
<term>Class I histocompatibility antigen</term>
<term>Cytotoxicity</term>
<term>H-2-System</term>
<term>Influenzavirus</term>
<term>Major histocompatibility system</term>
<term>Molecular processing</term>
<term>Mouse</term>
<term>Peptides</term>
<term>Recognition</term>
<term>Synthetic product</term>
<term>T-Lymphocyte</term>
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<keywords scheme="Pascal" xml:lang="fr"><term>Souris</term>
<term>Influenzavirus</term>
<term>Reconnaissance</term>
<term>Système H-2</term>
<term>Système histocompatibilité majeur</term>
<term>Lymphocyte T</term>
<term>Antigène histocompatibilité classe I</term>
<term>Cytotoxicité</term>
<term>Maturation moléculaire</term>
<term>Présentation antigène</term>
<term>Peptide</term>
<term>Produit synthétique</term>
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<front><div type="abstract" xml:lang="en">The transmembrane hydrophobic domain of the type A influenza A/JAPAN/305/57 (H2N2) hemagglutinin (HA) contains an immunodominant site encompassing amino acids 523-545 (J523-545) recognized by class I MHC-restricted cytolytic T lymphocytes (CTL). Class I CTL of two fine specificity subsets map to this transmembrane (TM) site. One of these CTL subpopulations is subtype specific</div>
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<affiliations><list><country><li>États-Unis</li>
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<tree><noCountry><name sortKey="Gorka, J" sort="Gorka, J" uniqKey="Gorka J" first="J." last="Gorka">J. Gorka</name>
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<country name="États-Unis"><noRegion><name sortKey="Milligan, G N" sort="Milligan, G N" uniqKey="Milligan G" first="G. N." last="Milligan">G. N. Milligan</name>
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<name sortKey="Braciale, T J" sort="Braciale, T J" uniqKey="Braciale T" first="T. J." last="Braciale">T. J. Braciale</name>
<name sortKey="Braciale, V L" sort="Braciale, V L" uniqKey="Braciale V" first="V. L." last="Braciale">V. L. Braciale</name>
<name sortKey="Morrison, L A" sort="Morrison, L A" uniqKey="Morrison L" first="L. A." last="Morrison">L. A. Morrison</name>
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