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The recognition of a viral antigenic moiety by class I MHC-restricted cytolytic T lymphocytes is limited by the availability of the endogenously processed antigen

Identifieur interne : 002231 ( Main/Merge ); précédent : 002230; suivant : 002232

The recognition of a viral antigenic moiety by class I MHC-restricted cytolytic T lymphocytes is limited by the availability of the endogenously processed antigen

Auteurs : G. N. Milligan [États-Unis] ; L. A. Morrison [États-Unis] ; J. Gorka ; V. L. Braciale [États-Unis] ; T. J. Braciale [États-Unis]

Source :

RBID : Pascal:92-0658912

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English descriptors

Abstract

The transmembrane hydrophobic domain of the type A influenza A/JAPAN/305/57 (H2N2) hemagglutinin (HA) contains an immunodominant site encompassing amino acids 523-545 (J523-545) recognized by class I MHC-restricted cytolytic T lymphocytes (CTL). Class I CTL of two fine specificity subsets map to this transmembrane (TM) site. One of these CTL subpopulations is subtype specific

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Pascal:92-0658912

Le document en format XML

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<term>Major histocompatibility system</term>
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<div type="abstract" xml:lang="en">The transmembrane hydrophobic domain of the type A influenza A/JAPAN/305/57 (H2N2) hemagglutinin (HA) contains an immunodominant site encompassing amino acids 523-545 (J523-545) recognized by class I MHC-restricted cytolytic T lymphocytes (CTL). Class I CTL of two fine specificity subsets map to this transmembrane (TM) site. One of these CTL subpopulations is subtype specific</div>
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