H2N2V1, Main, Exploration, bibRecord, 001E48

Recognition of an immunoglobulin VH epitope by influenza virus-specific class I major histocompatibility complex-restricted cytolytic T lymphocytes

Identifieur interne : 001E48 ( Main/Exploration ); précédent : 001E47; suivant : 001E49

Recognition of an immunoglobulin VH epitope by influenza virus-specific class I major histocompatibility complex-restricted cytolytic T lymphocytes

Auteurs : WUXIONG CAO [États-Unis] ; B. A. Myers-Powell ; T. J. Braciale

Source :

The Journal of experimental medicine [ 0022-1007 ] ; 1994.

RBID : Pascal:94-0157851

Descripteurs français

Pascal (Inist)
- Lymphocyte T, Cytotoxicité, Reconnaissance, Antigène, Influenzavirus, Immunomodulation, Immunité croisée, Région variable, Chaîne peptidique lourde, Immunoglobuline, Antigène histocompatibilité classe I, Souris, Réponse immune, Restriction histocompatibilité.

English descriptors

KwdEn :
- Antigen, Class I histocompatibility antigen, Cross immunity, Cytotoxicity, Heavy peptide chain, Immune response, Immunoglobulins, Immunomodulation, Influenzavirus, Mouse, Recognition, T-Lymphocyte, Variable region.

Abstract

There are two immunogenic sites on the type A influenza A/Japan/57 (H2N2) hemagglutinin (HA) that can be recognized by class I major histocompatibility complex (MHC), H-2K^d-restricted cytolytic T lymphocytes (CTLs). One of these sites encompases two distinct partially overlapping epitopes, which span HA residues 204-212 and 210-219. During the analysis of the fine specificity of CTL clones directed to the HA 210-219 epitope, we found that one clone 40-2 also recognized the myeloma cell line P3x63-Ag8

Affiliations:

États-Unis

Links toward previous steps (curation, corpus...)

to stream PascalFrancis, to step Corpus: 000096
to stream PascalFrancis, to step Curation: 000118
to stream PascalFrancis, to step Checkpoint: 000094
to stream Main, to step Merge: 001F31
to stream Main, to step Curation: 001E48

Le document en format XML

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 epitope by influenza virus-specific class I major histocompatibility complex-restricted cytolytic T lymphocytes</title>
<author><name sortKey="Wuxiong Cao" sort="Wuxiong Cao" uniqKey="Wuxiong Cao" last="Wuxiong Cao">WUXIONG CAO</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Univ. Virginia health sci. cent., dep. microbiology pathology, Beirne B. Carter cent. immunology res.</s1>
<s2>Charlottesville VA 22908</s2>
<s3>USA</s3>
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<country>États-Unis</country>
<wicri:noRegion>Charlottesville VA 22908</wicri:noRegion>
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<author><name sortKey="Myers Powell, B A" sort="Myers Powell, B A" uniqKey="Myers Powell B" first="B. A." last="Myers-Powell">B. A. Myers-Powell</name>
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<author><name sortKey="Braciale, T J" sort="Braciale, T J" uniqKey="Braciale T" first="T. J." last="Braciale">T. J. Braciale</name>
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<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">Recognition of an immunoglobulin V<sub>H</sub>
 epitope by influenza virus-specific class I major histocompatibility complex-restricted cytolytic T lymphocytes</title>
<author><name sortKey="Wuxiong Cao" sort="Wuxiong Cao" uniqKey="Wuxiong Cao" last="Wuxiong Cao">WUXIONG CAO</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Univ. Virginia health sci. cent., dep. microbiology pathology, Beirne B. Carter cent. immunology res.</s1>
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<author><name sortKey="Myers Powell, B A" sort="Myers Powell, B A" uniqKey="Myers Powell B" first="B. A." last="Myers-Powell">B. A. Myers-Powell</name>
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<author><name sortKey="Braciale, T J" sort="Braciale, T J" uniqKey="Braciale T" first="T. J." last="Braciale">T. J. Braciale</name>
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<series><title level="j" type="main">The Journal of experimental medicine</title>
<title level="j" type="abbreviated">J. exp. med.</title>
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<imprint><date when="1994">1994</date>
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<seriesStmt><title level="j" type="main">The Journal of experimental medicine</title>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Antigen</term>
<term>Class I histocompatibility antigen</term>
<term>Cross immunity</term>
<term>Cytotoxicity</term>
<term>Heavy peptide chain</term>
<term>Immune response</term>
<term>Immunoglobulins</term>
<term>Immunomodulation</term>
<term>Influenzavirus</term>
<term>Mouse</term>
<term>Recognition</term>
<term>T-Lymphocyte</term>
<term>Variable region</term>
</keywords>
<keywords scheme="Pascal" xml:lang="fr"><term>Lymphocyte T</term>
<term>Cytotoxicité</term>
<term>Reconnaissance</term>
<term>Antigène</term>
<term>Influenzavirus</term>
<term>Immunomodulation</term>
<term>Immunité croisée</term>
<term>Région variable</term>
<term>Chaîne peptidique lourde</term>
<term>Immunoglobuline</term>
<term>Antigène histocompatibilité classe I</term>
<term>Souris</term>
<term>Réponse immune</term>
<term>Restriction histocompatibilité</term>
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</teiHeader>
<front><div type="abstract" xml:lang="en">There are two immunogenic sites on the type A influenza A/Japan/57 (H2N2) hemagglutinin (HA) that can be recognized by class I major histocompatibility complex (MHC), H-2K<sup>d</sup>
-restricted cytolytic T lymphocytes (CTLs). One of these sites encompases two distinct partially overlapping epitopes, which span HA residues 204-212 and 210-219. During the analysis of the fine specificity of CTL clones directed to the HA 210-219 epitope, we found that one clone 40-2 also recognized the myeloma cell line P3x63-Ag8</div>
</front>
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<affiliations><list><country><li>États-Unis</li>
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Recognition of an immunoglobulin VH epitope by influenza virus-specific class I major histocompatibility complex-restricted cytolytic T lymphocytes

Recognition of an immunoglobulin VH epitope by influenza virus-specific class I major histocompatibility complex-restricted cytolytic T lymphocytes

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri