H2N2V1, Main, Exploration, bibRecord, 001B51

Discovery of anti-influenza A virus activity of a corynanthe-type indole alkaloid, hirsutine, in vitro and the structure-activity relationship of natural and synthetic analogs

Identifieur interne : 001B51 ( Main/Exploration ); précédent : 001B50; suivant : 001B52

Discovery of anti-influenza A virus activity of a corynanthe-type indole alkaloid, hirsutine, in vitro and the structure-activity relationship of natural and synthetic analogs

Auteurs : Hiromitsu Takayama [Japon] ; Yasuo Iimura [Japon] ; Mariko Kitajima [Japon] ; Norio Aimi [Japon] ; Kenji Konno [Japon] ; Hiroshi Inoue [Japon] ; Masatoshi Fujiwara [Japon] ; Tadashi Mizuta [Japon] ; Tomoyuki Yokota [Japon] ; Shiro Shigeta [Japon] ; Kenji Tokuhisa [Japon] ; Yasuaki Hanasaki [Japon] ; Kimio Katsuura [Japon]

Source :

Bioorganic & Medicinal Chemistry Letters [ 0960-894X ] ; 1997.

RBID : ISTEX:0608D0AD08C003A96AE17CEB82C86548FE07877D

English descriptors

Teeft :
- Alkaloid, Derivative, Effective concentration, Fukushima japan, Hirsutine, Indole, Indole alkaloid, Influenza, Inhibitory effect, Konno, Mdck, Preliminary findings, Shigeta, Synthetic derivatives, Virus activity, Yokota.

Abstract

Abstract: An indole alkaloid, hirsutine (1), was found to exhibit potent inhibitory effect against influenza A virus in vitro, and the essential structural feature for revealing the activity was elucidated by study of the structure-activity relationship using natural and synthetic derivatives of 1.

Graphicgr1

Url:

https://api.istex.fr/ark:/67375/6H6-N1JCHPWS-7/fulltext.pdf

DOI: 10.1016/S0960-894X(97)10154-8

Affiliations:

Japon

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Le document en format XML

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<front><div type="abstract" xml:lang="en">Abstract: An indole alkaloid, hirsutine (1), was found to exhibit potent inhibitory effect against influenza A virus in vitro, and the essential structural feature for revealing the activity was elucidated by study of the structure-activity relationship using natural and synthetic derivatives of 1.</div>
<div type="abstract">Graphicgr1 </div>
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<tree><country name="Japon"><noRegion><name sortKey="Takayama, Hiromitsu" sort="Takayama, Hiromitsu" uniqKey="Takayama H" first="Hiromitsu" last="Takayama">Hiromitsu Takayama</name>
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<name sortKey="Aimi, Norio" sort="Aimi, Norio" uniqKey="Aimi N" first="Norio" last="Aimi">Norio Aimi</name>
<name sortKey="Fujiwara, Masatoshi" sort="Fujiwara, Masatoshi" uniqKey="Fujiwara M" first="Masatoshi" last="Fujiwara">Masatoshi Fujiwara</name>
<name sortKey="Hanasaki, Yasuaki" sort="Hanasaki, Yasuaki" uniqKey="Hanasaki Y" first="Yasuaki" last="Hanasaki">Yasuaki Hanasaki</name>
<name sortKey="Iimura, Yasuo" sort="Iimura, Yasuo" uniqKey="Iimura Y" first="Yasuo" last="Iimura">Yasuo Iimura</name>
<name sortKey="Inoue, Hiroshi" sort="Inoue, Hiroshi" uniqKey="Inoue H" first="Hiroshi" last="Inoue">Hiroshi Inoue</name>
<name sortKey="Katsuura, Kimio" sort="Katsuura, Kimio" uniqKey="Katsuura K" first="Kimio" last="Katsuura">Kimio Katsuura</name>
<name sortKey="Kitajima, Mariko" sort="Kitajima, Mariko" uniqKey="Kitajima M" first="Mariko" last="Kitajima">Mariko Kitajima</name>
<name sortKey="Konno, Kenji" sort="Konno, Kenji" uniqKey="Konno K" first="Kenji" last="Konno">Kenji Konno</name>
<name sortKey="Mizuta, Tadashi" sort="Mizuta, Tadashi" uniqKey="Mizuta T" first="Tadashi" last="Mizuta">Tadashi Mizuta</name>
<name sortKey="Shigeta, Shiro" sort="Shigeta, Shiro" uniqKey="Shigeta S" first="Shiro" last="Shigeta">Shiro Shigeta</name>
<name sortKey="Tokuhisa, Kenji" sort="Tokuhisa, Kenji" uniqKey="Tokuhisa K" first="Kenji" last="Tokuhisa">Kenji Tokuhisa</name>
<name sortKey="Yokota, Tomoyuki" sort="Yokota, Tomoyuki" uniqKey="Yokota T" first="Tomoyuki" last="Yokota">Tomoyuki Yokota</name>
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Discovery of anti-influenza A virus activity of a corynanthe-type indole alkaloid, hirsutine, in vitro and the structure-activity relationship of natural and synthetic analogs

Discovery of anti-influenza A virus activity of a corynanthe-type indole alkaloid, hirsutine, in vitro and the structure-activity relationship of natural and synthetic analogs

Source :

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri