Antiviral agents in the critically ill child
Identifieur interne : 001963 ( Main/Exploration ); précédent : 001962; suivant : 001964Antiviral agents in the critically ill child
Auteurs : Flor M. MunozSource :
- Seminars in Pediatric Infectious Diseases [ 1045-1870 ] ; 2000.
English descriptors
- Teeft :
- Active compound, Active diphosphate form, Acute influenza, Acyclovir, Adenovirus infections, Adequate hydration, Amantadine, American academy, Analogue, Antimicrob agents chemother, Antimicrobial agents, Antiviral, Antiviral activity, Antiviral agents, Antiviral drugs, Baylor college, Care unit, Cellular kinases, Chain terminator, Chronic disease, Cidofovir, Clin microbiol, Clinical studies, Clinical trials, Competitive inhibition, Cytomegalovirus, Disease control, Dos, Enteroviral meningitis, Exact mechanism, Experimental influenza, Famciclovir, Foscarnet, Ganciclovir, Hayden, Healthy adults, Hepatitis, Hepatitis viruses, Herpesviruses, Higher doses, Host cells, Immunocompromised, Immunocompromised child, Immunocompromised children, Immunocompromised hosts, Immunocompromised patients, Infection, Infectious diseases, Influenza, Influenza virus infections, Influenza viruses, Inhaled zanamavir, Inhibitor, Initial phosphorylation, Intensive care unit, Interferon, Interferon alfa, Interscience conference, Intravenous, Intravenous administration, Kinase, Liver disease, Major surface glycoproteins, Mechanical ventilation, Munoz, Mutation, Neonatal period, Neuraminidase, Neuraminidase inhibitor zanamavir, Neuraminidase inhibitors, Nucleoside, Nucleoside analogues, Other herpesviruses, Paramyxovirus, Pediatr, Pediatric, Persistent response rate, Pharmacokinetic properties, Picornavirus, Pleconaril, Polymerase, Potent inhibitor, Prophylaxis, Protease inhibitors, Pyrophosphate binding site, Renal function, Replication, Respiratory failure, Respiratory infections, Respiratory syncytial virus, Respiratory tract disease, Rhinovirus, Ribavirin, Rimantadine, Saunders company, Severe illness, Side effects, Significant toxicity, Thymidine, Thymidine kinase, Tract disease, Triphosphate forms, Valacyclovir, Viral, Viral illnesses, Viral infections, Viral replication, Viral resistance, Virus, Virus infections, Zanamavir.
Abstract
Abstract: The treatment for most viral infections in children primarily is supportive. Severe viral illnesses and significant secondary complications that require treatment in the intensive care unit may occur in immunocompromised patients and also in infants and children who were previously healthy. Antiviral agents with specific activity against certain respiratory viruses, herpesviruses, and enteric viruses are available. New drugs are under development, and their use in pediatric patients is a subject of active research. The clinician's knowledge of the mechanisms of action, spectrum of activity, and side effects of these drugs is an important tool for their judicious use in the treatment of the critically ill child. Copyright © 2000 by W.B. Saunders Company
Url:
DOI: 10.1053/spid.0110035
Affiliations:
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