Immunology of avian influenza virus: a review
Identifieur interne : 001913 ( Main/Exploration ); précédent : 001912; suivant : 001914Immunology of avian influenza virus: a review
Auteurs : D. L Suarez [États-Unis] ; S. Schultz-Cherry [États-Unis]Source :
- Developmental and Comparative Immunology [ 0145-305X ] ; 2000.
English descriptors
- Teeft :
- Anas platyrhynchos, Antibody, Antibody response, Antibody responses, Antigenic, Antigenic drift, Antiviral activity, Assay, Avian, Avian macrophages, Avian virus, Avian virus infection, Avian virus infections, Avian viruses, Boca raton, Cellular immunity, Comparative immunology, Competitive elisa, Cytokine, Duck, Easterday, Elisa, Fowlpox, Growth factor beta, Haller, Hemagglutinin, High mortality, Hinshaw, Host species, Hpai, Hpai viruses, Immune, Immune response, Immunol, Immunology, Immunosorbent assay, Important role, Infection, Interferon, Interferon cytokine, Internal proteins, Kawaoka, Lymphocyte, Macrophage, Mammal, Mammalian species, Molecular characterization, Mpai, Mpai viruses, Mucosal, Neuraminidase, Neutralizing, Neutralizing antibody, Newcastle disease virus, Nucleoprotein, Pathogenesis, Pathogenic, Pathogenicity, Protective immunity, Replication, Respiratory burst, States animal health association, Suarez, Subtypes, Subunit vaccines, Surface proteins, Swayne, Vaccination, Vaccine, Viral, Viral replication, Virol, Virulent, Virus, Virus infection, Virus particle, Wild birds, Wild ducks.
Abstract
Abstract: Avian influenza virus can cause serious disease in a wide variety of birds and mammals, but its natural host range is in wild ducks, gulls, and shorebirds. Infections in poultry can be inapparent or cause respiratory disease, decreases in production, or a rapidly fatal systemic disease known as highly pathogenic avian influenza (HPAI). For the protection of poultry, neutralizing antibody to the hemagglutinin and neuraminidase proteins provide the primary protection against disease. A variety of vaccines elicit neutralizing antibody, including killed whole virus vaccines and fowl-pox recombinant vaccines. Antigenic drift of influenza viruses appears to be less important in causing vaccine failures in poultry as compared to humans. The cytotoxic T lymphocyte response can reduce viral shedding in mildly pathogenic avian influenza viruses, but provides questionable protection against HPAI. Influenza viruses can directly affect the immune response of infected birds, and the role of the Mx gene, interferons, and other cytokines in protection from disease remains unknown.
Url:
DOI: 10.1016/S0145-305X(99)00078-6
Affiliations:
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Le document en format XML
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Infections in poultry can be inapparent or cause respiratory disease, decreases in production, or a rapidly fatal systemic disease known as highly pathogenic avian influenza (HPAI). For the protection of poultry, neutralizing antibody to the hemagglutinin and neuraminidase proteins provide the primary protection against disease. A variety of vaccines elicit neutralizing antibody, including killed whole virus vaccines and fowl-pox recombinant vaccines. Antigenic drift of influenza viruses appears to be less important in causing vaccine failures in poultry as compared to humans. The cytotoxic T lymphocyte response can reduce viral shedding in mildly pathogenic avian influenza viruses, but provides questionable protection against HPAI. Influenza viruses can directly affect the immune response of infected birds, and the role of the Mx gene, interferons, and other cytokines in protection from disease remains unknown.</div></front></TEI><affiliations><list><country><li>États-Unis</li></country><region><li>Géorgie (États-Unis)</li></region></list><tree><country name="États-Unis"><region name="Géorgie (États-Unis)"><name sortKey="Suarez, D L" sort="Suarez, D L" uniqKey="Suarez D" first="D. L" last="Suarez">D. L Suarez</name></region><name sortKey="Schultz Cherry, S" sort="Schultz Cherry, S" uniqKey="Schultz Cherry S" first="S" last="Schultz-Cherry">S. Schultz-Cherry</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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