Influenzavirus‐Neuraminidase und eine sekundäre Sialinsäure‐ Bindungsstelle – Fakt oder Fiktion?
Identifieur interne : 000B43 ( Main/Exploration ); précédent : 000B42; suivant : 000B44Influenzavirus‐Neuraminidase und eine sekundäre Sialinsäure‐ Bindungsstelle – Fakt oder Fiktion?
Auteurs : Jimmy C. C. Lai [République populaire de Chine] ; Jean-Michel Garcia [République populaire de Chine] ; Jeffrey C. Dyason [Australie] ; Raphael Böhm [Australie] ; Paul D. Madge [Australie] ; Faith J. Rose [Australie] ; John M. Nicholls [République populaire de Chine] ; J. S. Malik Peiris [République populaire de Chine] ; Thomas Haselhorst [Australie] ; Mark Von Tzstein [Australie]Source :
- Angewandte Chemie [ 0044-8249 ] ; 2012-02-27.
Abstract
Die biologische Bedeutung einer sekundären Sialinsäure‐Bindungsstelle in Influenzavirus‐Neuraminidasen war lange unklar. Neuen Daten zufolge ist nach Blockieren des aktiven Zentrums Influenzavirus‐ähnlicher Partikel mit Oseltamivir‐Carboxylat weiterhin eine Restbindung von α(2,3)‐Sialyllactose vorhanden. Sialyllactose muss also an eine sekundäre Sialinsäure‐Bindungsstelle binden (Bild: sekundäre Bindungsstelle der Vogelgrippe‐Influenza‐Neuraminidase (Docking‐Studie).
Url:
DOI: 10.1002/ange.201108245
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Istex, to step Corpus: 000A50
- to stream Istex, to step Curation: 000A50
- to stream Istex, to step Checkpoint: 000120
- to stream Main, to step Merge: 000B46
- to stream Main, to step Curation: 000B43
Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="de">Influenzavirus‐Neuraminidase und eine sekundäre Sialinsäure‐ Bindungsstelle – Fakt oder Fiktion?</title><author><name sortKey="Lai, Jimmy C C" sort="Lai, Jimmy C C" uniqKey="Lai J" first="Jimmy C. C." last="Lai">Jimmy C. C. Lai</name></author><author><name sortKey="Garcia, Jean Ichel" sort="Garcia, Jean Ichel" uniqKey="Garcia J" first="Jean-Michel" last="Garcia">Jean-Michel Garcia</name></author><author><name sortKey="Dyason, Jeffrey C" sort="Dyason, Jeffrey C" uniqKey="Dyason J" first="Jeffrey C." last="Dyason">Jeffrey C. Dyason</name></author><author><name sortKey="Bohm, Raphael" sort="Bohm, Raphael" uniqKey="Bohm R" first="Raphael" last="Böhm">Raphael Böhm</name></author><author><name sortKey="Madge, Paul D" sort="Madge, Paul D" uniqKey="Madge P" first="Paul D." last="Madge">Paul D. Madge</name></author><author><name sortKey="Rose, Faith J" sort="Rose, Faith J" uniqKey="Rose F" first="Faith J." last="Rose">Faith J. Rose</name></author><author><name sortKey="Nicholls, John M" sort="Nicholls, John M" uniqKey="Nicholls J" first="John M." last="Nicholls">John M. Nicholls</name></author><author><name sortKey="Peiris, J S Malik" sort="Peiris, J S Malik" uniqKey="Peiris J" first="J. S. Malik" last="Peiris">J. S. Malik Peiris</name></author><author><name sortKey="Haselhorst, Thomas" sort="Haselhorst, Thomas" uniqKey="Haselhorst T" first="Thomas" last="Haselhorst">Thomas Haselhorst</name></author><author><name sortKey="Von Tzstein, Mark" sort="Von Tzstein, Mark" uniqKey="Von Tzstein M" first="Mark" last="Von Tzstein">Mark Von Tzstein</name></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:C398B791140B8207338EFA9A31663BA23A65CB6A</idno><date when="2012" year="2012">2012</date><idno type="doi">10.1002/ange.201108245</idno><idno type="url">https://api.istex.fr/ark:/67375/WNG-MT8TW9LD-S/fulltext.pdf</idno><idno type="wicri:Area/Istex/Corpus">000A50</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">000A50</idno><idno type="wicri:Area/Istex/Curation">000A50</idno><idno type="wicri:Area/Istex/Checkpoint">000120</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Checkpoint">000120</idno><idno type="wicri:doubleKey">0044-8249:2012:Lai J:influenzavirus:neuraminidase:und</idno><idno type="wicri:Area/Main/Merge">000B46</idno><idno type="wicri:Area/Main/Curation">000B43</idno><idno type="wicri:Area/Main/Exploration">000B43</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main">Influenzavirus‐Neuraminidase und eine sekundäre Sialinsäure‐ Bindungsstelle – Fakt oder Fiktion?</title><author><name sortKey="Lai, Jimmy C C" sort="Lai, Jimmy C C" uniqKey="Lai J" first="Jimmy C. C." last="Lai">Jimmy C. C. Lai</name><affiliation wicri:level="1"><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Hong Kong University‐Pasteur Research Centre</wicri:regionArea></affiliation></author><author><name sortKey="Garcia, Jean Ichel" sort="Garcia, Jean Ichel" uniqKey="Garcia J" first="Jean-Michel" last="Garcia">Jean-Michel Garcia</name><affiliation wicri:level="1"><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Hong Kong University‐Pasteur Research Centre</wicri:regionArea></affiliation></author><author><name sortKey="Dyason, Jeffrey C" sort="Dyason, Jeffrey C" uniqKey="Dyason J" first="Jeffrey C." last="Dyason">Jeffrey C. Dyason</name><affiliation wicri:level="1"><country xml:lang="fr">Australie</country><wicri:regionArea>Institute for Glycomics, Gold Coast Campus, Griffith University, Queensland</wicri:regionArea><wicri:noRegion>Queensland</wicri:noRegion></affiliation></author><author><name sortKey="Bohm, Raphael" sort="Bohm, Raphael" uniqKey="Bohm R" first="Raphael" last="Böhm">Raphael Böhm</name><affiliation wicri:level="1"><country xml:lang="fr">Australie</country><wicri:regionArea>Institute for Glycomics, Gold Coast Campus, Griffith University, Queensland</wicri:regionArea><wicri:noRegion>Queensland</wicri:noRegion></affiliation></author><author><name sortKey="Madge, Paul D" sort="Madge, Paul D" uniqKey="Madge P" first="Paul D." last="Madge">Paul D. Madge</name><affiliation wicri:level="1"><country xml:lang="fr">Australie</country><wicri:regionArea>Institute for Glycomics, Gold Coast Campus, Griffith University, Queensland</wicri:regionArea><wicri:noRegion>Queensland</wicri:noRegion></affiliation></author><author><name sortKey="Rose, Faith J" sort="Rose, Faith J" uniqKey="Rose F" first="Faith J." last="Rose">Faith J. Rose</name><affiliation wicri:level="1"><country xml:lang="fr">Australie</country><wicri:regionArea>Institute for Glycomics, Gold Coast Campus, Griffith University, Queensland</wicri:regionArea><wicri:noRegion>Queensland</wicri:noRegion></affiliation></author><author><name sortKey="Nicholls, John M" sort="Nicholls, John M" uniqKey="Nicholls J" first="John M." last="Nicholls">John M. Nicholls</name><affiliation wicri:level="1"><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Pathology</wicri:regionArea></affiliation></author><author><name sortKey="Peiris, J S Malik" sort="Peiris, J S Malik" uniqKey="Peiris J" first="J. S. Malik" last="Peiris">J. S. Malik Peiris</name><affiliation wicri:level="1"><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Centre of Influenza Research, School of Public Health; HKU‐Pasteur Research Centre</wicri:regionArea><wicri:noRegion>School of Public Health; HKU‐Pasteur Research Centre</wicri:noRegion></affiliation></author><author><name sortKey="Haselhorst, Thomas" sort="Haselhorst, Thomas" uniqKey="Haselhorst T" first="Thomas" last="Haselhorst">Thomas Haselhorst</name><affiliation wicri:level="1"><country xml:lang="fr">Australie</country><wicri:regionArea>Institute for Glycomics, Gold Coast Campus, Griffith University, Queensland</wicri:regionArea><wicri:noRegion>Queensland</wicri:noRegion></affiliation><affiliation wicri:level="1"><country wicri:rule="url">Australie</country></affiliation><affiliation wicri:level="1"><country xml:lang="fr">Australie</country><wicri:regionArea>Correspondence address: Institute for Glycomics, Gold Coast Campus, Griffith University, Queensland</wicri:regionArea><wicri:noRegion>Queensland</wicri:noRegion></affiliation></author><author><name sortKey="Von Tzstein, Mark" sort="Von Tzstein, Mark" uniqKey="Von Tzstein M" first="Mark" last="Von Tzstein">Mark Von Tzstein</name><affiliation wicri:level="1"><country xml:lang="fr">Australie</country><wicri:regionArea>Institute for Glycomics, Gold Coast Campus, Griffith University, Queensland</wicri:regionArea><wicri:noRegion>Queensland</wicri:noRegion></affiliation><affiliation wicri:level="1"><country wicri:rule="url">Australie</country></affiliation><affiliation wicri:level="1"><country xml:lang="fr">Australie</country><wicri:regionArea>Correspondence address: Institute for Glycomics, Gold Coast Campus, Griffith University, Queensland</wicri:regionArea><wicri:noRegion>Queensland</wicri:noRegion></affiliation></author></analytic><monogr></monogr><series><title level="j" type="main">Angewandte Chemie</title><title level="j" type="alt">ANGEWANDTE CHEMIE</title><idno type="ISSN">0044-8249</idno><idno type="eISSN">1521-3757</idno><imprint><biblScope unit="vol">124</biblScope><biblScope unit="issue">9</biblScope><biblScope unit="page" from="2264">2264</biblScope><biblScope unit="page" to="2267">2267</biblScope><biblScope unit="page-count">4</biblScope><publisher>WILEY‐VCH Verlag</publisher><pubPlace>Weinheim</pubPlace><date type="published" when="2012-02-27">2012-02-27</date></imprint><idno type="ISSN">0044-8249</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0044-8249</idno></seriesStmt></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="de">Die biologische Bedeutung einer sekundären Sialinsäure‐Bindungsstelle in Influenzavirus‐Neuraminidasen war lange unklar. Neuen Daten zufolge ist nach Blockieren des aktiven Zentrums Influenzavirus‐ähnlicher Partikel mit Oseltamivir‐Carboxylat weiterhin eine Restbindung von α(2,3)‐Sialyllactose vorhanden. Sialyllactose muss also an eine sekundäre Sialinsäure‐Bindungsstelle binden (Bild: sekundäre Bindungsstelle der Vogelgrippe‐Influenza‐Neuraminidase (Docking‐Studie).</div></front></TEI><affiliations><list><country><li>Australie</li><li>République populaire de Chine</li></country></list><tree><country name="République populaire de Chine"><noRegion><name sortKey="Lai, Jimmy C C" sort="Lai, Jimmy C C" uniqKey="Lai J" first="Jimmy C. C." last="Lai">Jimmy C. C. Lai</name></noRegion><name sortKey="Garcia, Jean Ichel" sort="Garcia, Jean Ichel" uniqKey="Garcia J" first="Jean-Michel" last="Garcia">Jean-Michel Garcia</name><name sortKey="Nicholls, John M" sort="Nicholls, John M" uniqKey="Nicholls J" first="John M." last="Nicholls">John M. Nicholls</name><name sortKey="Peiris, J S Malik" sort="Peiris, J S Malik" uniqKey="Peiris J" first="J. S. Malik" last="Peiris">J. S. Malik Peiris</name></country><country name="Australie"><noRegion><name sortKey="Dyason, Jeffrey C" sort="Dyason, Jeffrey C" uniqKey="Dyason J" first="Jeffrey C." last="Dyason">Jeffrey C. Dyason</name></noRegion><name sortKey="Bohm, Raphael" sort="Bohm, Raphael" uniqKey="Bohm R" first="Raphael" last="Böhm">Raphael Böhm</name><name sortKey="Haselhorst, Thomas" sort="Haselhorst, Thomas" uniqKey="Haselhorst T" first="Thomas" last="Haselhorst">Thomas Haselhorst</name><name sortKey="Haselhorst, Thomas" sort="Haselhorst, Thomas" uniqKey="Haselhorst T" first="Thomas" last="Haselhorst">Thomas Haselhorst</name><name sortKey="Haselhorst, Thomas" sort="Haselhorst, Thomas" uniqKey="Haselhorst T" first="Thomas" last="Haselhorst">Thomas Haselhorst</name><name sortKey="Madge, Paul D" sort="Madge, Paul D" uniqKey="Madge P" first="Paul D." last="Madge">Paul D. Madge</name><name sortKey="Rose, Faith J" sort="Rose, Faith J" uniqKey="Rose F" first="Faith J." last="Rose">Faith J. Rose</name><name sortKey="Von Tzstein, Mark" sort="Von Tzstein, Mark" uniqKey="Von Tzstein M" first="Mark" last="Von Tzstein">Mark Von Tzstein</name><name sortKey="Von Tzstein, Mark" sort="Von Tzstein, Mark" uniqKey="Von Tzstein M" first="Mark" last="Von Tzstein">Mark Von Tzstein</name><name sortKey="Von Tzstein, Mark" sort="Von Tzstein, Mark" uniqKey="Von Tzstein M" first="Mark" last="Von Tzstein">Mark Von Tzstein</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/H2N2V1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000B43 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000B43 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Sante
|area= H2N2V1
|flux= Main
|étape= Exploration
|type= RBID
|clé= ISTEX:C398B791140B8207338EFA9A31663BA23A65CB6A
|texte= Influenzavirus‐Neuraminidase und eine sekundäre Sialinsäure‐ Bindungsstelle – Fakt oder Fiktion?
}}
| This area was generated with Dilib version V0.6.33. |  |