H2N2V1, Istex, Corpus, bibRecord, 000979

15 December News

Identifieur interne : 000979 ( Istex/Corpus ); précédent : 000978; suivant : 000980

15 December News

Auteurs : Donald Kaye

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Clinical Infectious Diseases [ 1058-4838 ] ; 2009.

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DOI: 10.1086/649586

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<sec id="sec1">

<title>Swine Flu Sends Mostly Under-25s to Hospital—CDC</title>

<p>20 October 2009 (Reuters Health [Maggie Fox])—Half of those hospitalized with the new H1N1 virus are under 25, a clear illustration that the pandemic is affecting the young disproportionately, United States (US) health officials said.</p>

<p>They said reports from 27 US states show 53% of people sick enough to be hospitalized with H1N1 flu are under the age of 25, with only 7% of hospitalizations among people 65 and older.</p>

<p>“This is really, really different from what we see with seasonal flu,” the Center for Disease Control and Prevention (CDC)'s Dr Anne Schuchat told reporters. “With seasonal flu, about 60% of hospitalizations occur in people 65 and over.”</p>

<p>And an analysis of 292 deaths from 28 states showed that younger people than usual are also dying, she said.</p>

<p>“Almost a quarter of deaths are occurring in young people under the age of 25. Specifically, 23.6% of the deaths are in that age group. About 65% of the deaths are in people 25 to 64 years of age,” Schuchat said.</p>

<p>Just 12% of deaths were among people over 65. In a normal year, 90% of those who die from flu are over 65.</p>

<p>With cooler weather, other viruses and infections are showing up, making the picture confusing.</p>

<p>Schuchat said influenza is being diagnosed in about 30% of all people showing up with “influenza-like illness,” symptoms that include cough, sore throat, fever, and aches.</p>

<p>Almost all influenza is turning out to be H1N1 rather than seasonal influenza and Schuchat said the tests often miss cases of H1N1, so the percentage may be higher.</p>

<p>Ordinary colds, group A streptococcus, which causes “strep throat,” and other infections can cause similar symptoms.</p>

<p><bold><italic>Editor's comment.</italic>
</bold>
 The US experience in terms of age mirrors closely the experience in other countries. For example, in Mexico, 87% of deaths and 71% of severe pneumonias occurred among patients aged 5–59 years, compared with 17% and 32%, respectively, during previous recent experience with seasonal influenza. Most deaths occurred in patients aged <50 years, compared with the 90% of deaths that occur in patients aged >65 years with seasonal influenza. It is also important to remember that, unlike previous experience, the pneumonias are mainly viral and not bacterial. (D.K.)</p>

</sec>

<sec id="sec2">

<title>Tests Show Flu Spreads from Schools</title>

<p>21 October 2009 (Reuters Health [Maggie Fox])—Results of tens of thousands of flu tests indicate that the pandemic H1N1 virus is spreading from school-aged children to the rest of the United States (US) population, makers of the tests say.</p>

<p>“Based on tests performed since Quest Diagnostics began offering H1N1 testing in May 2009, children between the ages of 5 to 14 have experienced higher overall rates of H1N1 positivity than any other age group,” the company said in its report.</p>

<p>The Quest test is a polymerase chain reaction (PCR) test—it magnifies the genetic material of the virus so it can be detected and is similar to the tests used by state health departments to confirm H1N1.</p>

<p>On-the-spot flu tests given in doctor's offices only tell if a person has influenza A or not. They cannot tell which strain, and they often miss the new H1N1 strain completely.</p>

<p>The US Centers for Disease Control and Prevention (CDC) has given up trying to count how many people have the new H1N1, saying only that is it well over a million. Only select cases are tested.</p>

<p>Dr Jay Lieberman, medical director for Quest Diagnostics and a pediatrician at the University of California, Irvine, says data from Quest's testing, based on 76,500 specimens taken between 11 May and 11 October 2009, can supplement the CDC's findings, which cover fewer than 5000 patients.</p>

<p>The sharp rise in cases in children came at the end of August and beginning of September, Lieberman told Reuters in a telephone interview.</p>

<p>“What is interesting is that we are now seeing delayed by several weeks a rise in other age groups—in the elderly, in people aged 50 to 64 and in children under 5 years of age,” Lieberman said.</p>

<p>Influenza often spreads from school-aged children to siblings, parents, and eventually grandparents.</p>

<p>“What we have seen in the pandemic so far is that the elderly have been relatively spared. That may start to change in the weeks ahead,” Lieberman said.</p>

<p>Many scientists think the elderly are less likely to be infected because they have some immunity to the H1N1 virus.</p>

<p>Lieberman said the findings show it is important to vaccinate children against influenza to slow the spread in the community.</p>

<p>Cases are evenly divided by gender, Quest said, and about half of all samples sent for testing—by doctor's offices, state and county health departments—turn out to be H1N1.</p>

<p><bold><italic>Editor's comment.</italic>
</bold>
 This is extremely useful because of the number of PCR tests available, compared with the CDC numbers. It is not at all surprising that school children are the predominant group infected early in the outbreak, with spread to the general population. In the past, the pattern always involved an initial spread to children and young working adults with later spread, often in the second or third wave, to older people who are less active and less likely to be exposed to crowds. It will be interesting to see just how much spread occurs to the older population this time, because many people in their late 50s and older have had experience with similar viruses prior to the 1957 H2N2 pandemic. (D.K.)</p>

</sec>

<sec id="sec3">

<title>US Advisers Decline to Push Gardasil for Boys</title>

<p>21 October 2009 (Reuters Health)—United States (US) vaccine advisers declined to press for the use of Merck & Co's Gardasil in boys and men, opting instead for “permissive” use.</p>

<p>The Advisory Committee on Immunization Practices (ACIP) voted almost unanimously to simply advise doctors they were free to recommend the vaccine for boys. The US Centers for Disease Control and Prevention currently recommends Gardasil for 11- and 12-year-old girls and for women 13 to 26 who have not been vaccinated.</p>

<p>Earlier this month, the US Food and Drug Administration approved Gardasil for preventing genital warts in boys and men ages 9 through 26.</p>

<p>The main reason the vaccine was approved was to prevent cervical cancer, which kills 4000 women a year in the US alone. But various strains of human papillomavirus (HPV) also cause disfiguring genital warts, anal and penile cancers, and head and neck cancers.</p>

<p>Some critics question if it is worth the cost to vaccinate against cervical cancer when its largely treatable if caught early. Immunizing boys for genital warts also raised concerns since the warts often clear up without treatment.</p>

<p>But other experts note the diseases caused by HPV affect both men and women, are transmitted sexually, and are very common.</p>

<p>The ACIP committee restricted its vote to the value of preventing genital warts, which is what the vaccine is approved for, and not the cancers, where there is less evidence of a benefit.</p>

<p><bold><italic>Editor's comment.</italic>
</bold>
 This cryptically worded recommendation concerning use of Gardasil for boys and men basically indicates a recommendation for optional or discretionary use as opposed to routine or universal use as in females. This rather tepid recommendation does not bode well for much use in boys and men. (D.K.)</p>

</sec>

<sec id="sec4">

<title>USDA Confirms H1N1 Flu in First US Hog</title>

<p>19 October 2009 (Reuters Health)—The pandemic H1N1 flu virus was confirmed in a sample from a hog exhibited at the Minnesota State Fair, the Agriculture Department said.</p>

<p>It was the first discovery in United States (US) hogs.</p>

<p>The discovery does not suggest infection of commercial herds, grown for slaughter, because show pigs and commercial herds are separate components of the swine industry and usually are not commingled, US Department of Agriculture (USDA) said in a statement.</p>

<p>Samples were taken from 26 August 26–1 September as part of a research project. Additional samples are being tested.</p>

<p>USDA said last week there was no direct link with an outbreak of H1N1 flu among teenagers housed in a dormitory at the fair at roughly the same time.</p>

<p>Agriculture Secretary Tom Vilsack said the World Organization for Animal Health says there is no reason to restrict trade in pork or pork products.</p>

<p>“People cannot get this flu from eating pork or pork products,” said Vilsack in a statement.</p>

<p><bold><italic>Editor's comment.</italic>
</bold>
 In fact, the pandemic H1N1 was also isolated from 3 pigs exhibited at the Minnesota State Fair this summer and has been isolated from pigs in multiple other countries. This should serve as no surprise, because pigs are susceptible to human influenza, and very similar (or perhaps identical) strains are thought to have been circulating in pigs for years before emergence of the current pandemic H1N1 strain. (D.K.)</p>

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HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000979 | SxmlIndent | more

HfdSelect -h $EXPLOR_AREA/Data/Istex/Corpus/biblio.hfd -nk 000979 | SxmlIndent | more

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{{Explor lien
   |wiki=    Sante
   |area=    H2N2V1
   |flux=    Istex
   |étape=   Corpus
   |type=    RBID
   |clé=     ISTEX:FDE605B754DB6F52311E57D90E7DF52525E69BAA
   |texte=   15 December News
}}

This area was generated with Dilib version V0.6.33.
Data generation: Tue Apr 14 19:59:40 2020. Site generation: Thu Mar 25 15:38:26 2021

	Serveur d'exploration H2N2
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.

Serveur d'exploration H2N2

15 December News

15 December News

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