Lack of cross‐immune reactivity against influenza H5N1 from seasonal influenza vaccine in humans
Identifieur interne : 000569 ( Istex/Corpus ); précédent : 000568; suivant : 000570Lack of cross‐immune reactivity against influenza H5N1 from seasonal influenza vaccine in humans
Auteurs : Julian W. Tang ; Karry L. K. Ngai ; Paul K. S. ChanSource :
- Journal of Medical Virology [ 0146-6615 ] ; 2008-11.
Abstract
In a small pilot study, sera from 10 healthy human volunteers were taken pre‐vaccine, then 1, 3, and 6 months post‐seasonal influenza immunization (using the 2005/2006 Northern hemisphere vaccine: A/New Caledonia/20/99(H1N1)‐like, A/California/7/2004(H3N2)‐like, and B/Shanghai/361/2002‐like strains). Eight out of 10 subjects demonstrated satisfactory HAI titers (≥40) after seasonal influenza vaccination between 1 and 6 months post‐vaccine. These sera were then tested for inhibitory activity against A/HK/483/97 and A/Thailand/1(KAN‐1)/04 H5N1 influenza viruses using standard hemagglutination inhibition and microneutralization assays. In contrast to several other studies in both humans and animals on the cross‐immunity between different influenza A viruses, antibodies produced to the influenza A(H1N1) component of the seasonal influenza vaccine showed no cross‐reactivity to these avian influenza A(H5N1) viruses. Possible reasons for this contrasting result are discussed. J. Med. Virol. 80:1992–1996, 2008. © 2008 Wiley‐Liss, Inc.
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DOI: 10.1002/jmv.21321
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ISTEX:3AA3B59181D9E3A52D039146E92B16F2E0E94C9ELe document en format XML
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Eight out of 10 subjects demonstrated satisfactory HAI titers (≥40) after seasonal influenza vaccination between 1 and 6 months post‐vaccine. These sera were then tested for inhibitory activity against A/HK/483/97 and A/Thailand/1(KAN‐1)/04 H5N1 influenza viruses using standard hemagglutination inhibition and microneutralization assays. In contrast to several other studies in both humans and animals on the cross‐immunity between different influenza A viruses, antibodies produced to the influenza A(H1N1) component of the seasonal influenza vaccine showed no cross‐reactivity to these avian influenza A(H5N1) viruses. Possible reasons for this contrasting result are discussed. J. Med. 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[2008]</json:string><json:string>[2006]</json:string><json:string>Gioia et al., 2008</json:string><json:string>Seo et al., 2002</json:string><json:string>Cannell et al., 2006, 2008</json:string><json:string>Kreijtz et al., 2008</json:string><json:string>WHO, 2005</json:string><json:string>Davey and Glass, 2008</json:string><json:string>Monto and Whitley, 2008</json:string><json:string>Oshitani et al., 2008</json:string><json:string>Roti et al., 2008</json:string><json:string>Tang et al., 2008</json:string><json:string>Smallman-Raynor and Cliff, 2007</json:string><json:string>Smith et al., 1933</json:string><json:string>Andreasen et al., 2008</json:string><json:string>Ehrlich et al., 2008</json:string><json:string>Tang et al.</json:string><json:string>Sandbulte et al., 2007</json:string><json:string>Nicholson et al., 2003</json:string><json:string>Maher and DeStefano, 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Virol. 80:1992–1996, 2008. © 2008 Wiley‐Liss, Inc.</p></abstract><textClass><keywords xml:lang="en"><term xml:id="kwd1">hemagglutinin</term><term xml:id="kwd2">neuraminidase</term><term xml:id="kwd3">hemagglutination inhibition</term><term xml:id="kwd4">microneutralization</term><term xml:id="kwd5">human</term><term xml:id="kwd6">mouse</term><term xml:id="kwd7">ferret</term></keywords><keywords rend="articleCategory"><term>Research Article</term></keywords></textClass><langUsage><language ident="en"></language></langUsage></profileDesc><revisionDesc><change when="2019-12-20" who="#istex" xml:id="pub2tei">formatting</change></revisionDesc></teiHeader></istex:fulltextTEI><json:item><extension>txt</extension><original>false</original><mimetype>text/plain</mimetype><uri>https://api.istex.fr/ark:/67375/WNG-6HWJCQCL-R/fulltext.txt</uri></json:item></fulltext><metadata><istex:metadataXml wicri:clean="Wiley, elements deleted: body"><istex:xmlDeclaration>version="1.0" encoding="UTF-8" standalone="yes"</istex:xmlDeclaration><istex:document><component version="2.0" type="serialArticle" xml:lang="en"><header><publicationMeta level="product"><publisherInfo><publisherName>Wiley Subscription Services, Inc., A Wiley Company</publisherName><publisherLoc>Hoboken</publisherLoc></publisherInfo><doi registered="yes">10.1002/(ISSN)1096-9071</doi><issn type="print">0146-6615</issn><issn type="electronic">1096-9071</issn><idGroup><id type="product" value="JMV"></id></idGroup><titleGroup><title type="main" xml:lang="en" sort="JOURNAL OF MEDICAL VIROLOGY">Journal of Medical Virology</title><title type="short">J. 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Virol.</title></titleGroup></publicationMeta><publicationMeta level="part" position="110"><doi origin="wiley" registered="yes">10.1002/jmv.v80:11</doi><numberingGroup><numbering type="journalVolume" number="80">80</numbering><numbering type="journalIssue">11</numbering></numberingGroup><coverDate startDate="2008-11">November 2008</coverDate></publicationMeta><publicationMeta level="unit" type="article" position="180" status="forIssue"><doi origin="wiley" registered="yes">10.1002/jmv.21321</doi><idGroup><id type="unit" value="JMV21321"></id></idGroup><countGroup><count type="pageTotal" number="5"></count></countGroup><titleGroup><title type="articleCategory">Research Article</title></titleGroup><copyright ownership="publisher">Copyright © 2008 Wiley‐Liss, Inc.</copyright><eventGroup><event type="manuscriptAccepted" date="2008-07-17"></event><event type="firstOnline" date="2008-09-23"></event><event type="publishedOnlineFinalForm" date="2008-09-23"></event><event type="xmlConverted" agent="Converter:JWSART34_TO_WML3G version:2.3.2 mode:FullText source:HeaderRef result:HeaderRef" date="2010-03-15"></event><event type="xmlConverted" agent="Converter:WILEY_ML3G_TO_WILEY_ML3GV2 version:4.0.1" date="2014-03-20"></event><event type="xmlConverted" agent="Converter:WML3G_To_WML3G version:4.1.7 mode:FullText,remove_FC" date="2014-10-30"></event></eventGroup><numberingGroup><numbering type="pageFirst">1992</numbering><numbering type="pageLast">1996</numbering></numberingGroup><correspondenceTo>Department of Microbiology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR, China.===</correspondenceTo><linkGroup><link type="toTypesetVersion" href="file:JMV.JMV21321.pdf"></link></linkGroup></publicationMeta><contentMeta><countGroup><count type="figureTotal" number="0"></count><count type="tableTotal" number="1"></count><count type="referenceTotal" number="38"></count><count type="wordTotal" number="1014"></count></countGroup><titleGroup><title type="main" xml:lang="en">Lack of cross‐immune reactivity against influenza H5N1 from seasonal influenza vaccine in humans</title><title type="short" xml:lang="en">No Influenza Vaccine Cross‐Immunity</title></titleGroup><creators><creator xml:id="au1" creatorRole="author" affiliationRef="#af1"><personName><givenNames>Julian W.</givenNames><familyName>Tang</familyName></personName></creator><creator xml:id="au2" creatorRole="author" affiliationRef="#af1"><personName><givenNames>Karry L.K.</givenNames><familyName>Ngai</familyName></personName></creator><creator xml:id="au3" creatorRole="author" affiliationRef="#af1" corresponding="yes"><personName><givenNames>Paul K.S.</givenNames><familyName>Chan</familyName></personName><contactDetails><email>paulkschan@cuhk.edu.hk</email></contactDetails></creator></creators><affiliationGroup><affiliation xml:id="af1" countryCode="CN" type="organization"><unparsedAffiliation>Department of Microbiology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR, China</unparsedAffiliation></affiliation></affiliationGroup><keywordGroup xml:lang="en" type="author"><keyword xml:id="kwd1">hemagglutinin</keyword><keyword xml:id="kwd2">neuraminidase</keyword><keyword xml:id="kwd3">hemagglutination inhibition</keyword><keyword xml:id="kwd4">microneutralization</keyword><keyword xml:id="kwd5">human</keyword><keyword xml:id="kwd6">mouse</keyword><keyword xml:id="kwd7">ferret</keyword></keywordGroup><abstractGroup><abstract type="main" xml:lang="en"><title type="main">Abstract</title><p>In a small pilot study, sera from 10 healthy human volunteers were taken pre‐vaccine, then 1, 3, and 6 months post‐seasonal influenza immunization (using the 2005/2006 Northern hemisphere vaccine: A/New Caledonia/20/99(H1N1)‐like, A/California/7/2004(H3N2)‐like, and B/Shanghai/361/2002‐like strains). Eight out of 10 subjects demonstrated satisfactory HAI titers (≥40) after seasonal influenza vaccination between 1 and 6 months post‐vaccine. These sera were then tested for inhibitory activity against A/HK/483/97 and A/Thailand/1(KAN‐1)/04 H5N1 influenza viruses using standard hemagglutination inhibition and microneutralization assays. In contrast to several other studies in both humans and animals on the cross‐immunity between different influenza A viruses, antibodies produced to the influenza A(H1N1) component of the seasonal influenza vaccine showed no cross‐reactivity to these avian influenza A(H5N1) viruses. Possible reasons for this contrasting result are discussed. J. Med. Virol. 80:1992–1996, 2008. © 2008 Wiley‐Liss, Inc.</p></abstract></abstractGroup></contentMeta></header></component></istex:document></istex:metadataXml><mods version="3.6"><titleInfo lang="en"><title>Lack of cross‐immune reactivity against influenza H5N1 from seasonal influenza vaccine in humans</title></titleInfo><titleInfo type="abbreviated" lang="en"><title>No Influenza Vaccine Cross‐Immunity</title></titleInfo><titleInfo type="alternative" contentType="CDATA" lang="en"><title>Lack of cross‐immune reactivity against influenza H5N1 from seasonal influenza vaccine in humans</title></titleInfo><name type="personal"><namePart type="given">Julian W.</namePart><namePart type="family">Tang</namePart><affiliation>Department of Microbiology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR, China</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Karry L.K.</namePart><namePart type="family">Ngai</namePart><affiliation>Department of Microbiology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR, China</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Paul K.S.</namePart><namePart type="family">Chan</namePart><affiliation>Department of Microbiology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR, China</affiliation><affiliation>E-mail: paulkschan@cuhk.edu.hk</affiliation><affiliation>Correspondence address: Department of Microbiology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR, China.===</affiliation><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre type="article" displayLabel="article" authority="ISTEX" authorityURI="https://content-type.data.istex.fr" valueURI="https://content-type.data.istex.fr/ark:/67375/XTP-6N5SZHKN-D">article</genre><originInfo><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><place><placeTerm type="text">Hoboken</placeTerm></place><dateIssued encoding="w3cdtf">2008-11</dateIssued><dateValid encoding="w3cdtf">2008-07-17</dateValid><copyrightDate encoding="w3cdtf">2008</copyrightDate></originInfo><language><languageTerm type="code" authority="rfc3066">en</languageTerm><languageTerm type="code" authority="iso639-2b">eng</languageTerm></language><physicalDescription><extent unit="figures">0</extent><extent unit="tables">1</extent><extent unit="references">38</extent><extent unit="words">1014</extent></physicalDescription><abstract lang="en">In a small pilot study, sera from 10 healthy human volunteers were taken pre‐vaccine, then 1, 3, and 6 months post‐seasonal influenza immunization (using the 2005/2006 Northern hemisphere vaccine: A/New Caledonia/20/99(H1N1)‐like, A/California/7/2004(H3N2)‐like, and B/Shanghai/361/2002‐like strains). Eight out of 10 subjects demonstrated satisfactory HAI titers (≥40) after seasonal influenza vaccination between 1 and 6 months post‐vaccine. These sera were then tested for inhibitory activity against A/HK/483/97 and A/Thailand/1(KAN‐1)/04 H5N1 influenza viruses using standard hemagglutination inhibition and microneutralization assays. In contrast to several other studies in both humans and animals on the cross‐immunity between different influenza A viruses, antibodies produced to the influenza A(H1N1) component of the seasonal influenza vaccine showed no cross‐reactivity to these avian influenza A(H5N1) viruses. Possible reasons for this contrasting result are discussed. J. Med. Virol. 80:1992–1996, 2008. © 2008 Wiley‐Liss, Inc.</abstract><subject lang="en"><genre>keywords</genre><topic>hemagglutinin</topic><topic>neuraminidase</topic><topic>hemagglutination inhibition</topic><topic>microneutralization</topic><topic>human</topic><topic>mouse</topic><topic>ferret</topic></subject><relatedItem type="host"><titleInfo><title>Journal of Medical Virology</title></titleInfo><titleInfo type="abbreviated"><title>J. Med. 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