Antiviral activity of the infusion (SHS‐174) from flowers of Sambucus nigra L., aerial parts of Hypericum perforatum L., and roots of Saponaria officinalis L. against influenza and herpes simplex viruses
Identifieur interne : 000417 ( Istex/Corpus ); précédent : 000416; suivant : 000418Antiviral activity of the infusion (SHS‐174) from flowers of Sambucus nigra L., aerial parts of Hypericum perforatum L., and roots of Saponaria officinalis L. against influenza and herpes simplex viruses
Auteurs : Julia Serkedjieva ; Nadia Manolova ; Izabella Zg Rniak-Nowosielska ; Barbara Zawili Ska ; Jan GrzybekSource :
- Phytotherapy Research [ 0951-418X ] ; 1990-06.
English descriptors
- Teeft :
- Aerial parts, Antiviral, Antiviral activity, Antiviral drugs, Antiviral effect, Antiviral properties, Cell cultures, Chick embryo fibroblasts, Cycle experiment, Different strains, Farmakopea polska, Fowl plague virus, Haemagglutination titres, Herpes, Herpes simplex virus replication, Herpes simplex virus type, Hypericum perforatum, Infectious process, Influenza, Influenza virus, Influenza viruses, Inhibitory action, Inhibitory effect, John wiley sons, Medical academy, Pharmaceutical botany, Phenolic acids, Phytotherapy research, Plant preparation, Protective index, Sambucus nigra, Saponaria oficinalis, Simplex, Tissue cultures, Various concentrations, Viral infection, Virucidal effect, Virus.
Abstract
The SHS‐174 preparation, a lyophilized infusion from flowers of Sambucus nigra L., aerial parts of Hypericum perforatum L., and roots of Saponaria officinalis (100 g; 70 g; 40 g) exhibited an antiviral effect. It inhibited the reproduction of different strains of influenza virus types A and B, both in vitro and in vivo, and herpes simplex virus type 1, in vitro. The preparation contains flavonoids, triterpene saponins, phenolic acids, tannins and polysaccharides which could be responsible for its antiviral properties.
Url:
DOI: 10.1002/ptr.2650040305
Links to Exploration step
ISTEX:00E8E67274B89F83F123CFD7FDCD2AA3329D7366Le document en format XML
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process</term><term>Influenza</term><term>Influenza virus</term><term>Influenza viruses</term><term>Inhibitory action</term><term>Inhibitory effect</term><term>John wiley sons</term><term>Medical academy</term><term>Pharmaceutical botany</term><term>Phenolic acids</term><term>Phytotherapy research</term><term>Plant preparation</term><term>Protective index</term><term>Sambucus nigra</term><term>Saponaria oficinalis</term><term>Simplex</term><term>Tissue cultures</term><term>Various concentrations</term><term>Viral infection</term><term>Virucidal effect</term><term>Virus</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The SHS‐174 preparation, a lyophilized infusion from flowers of Sambucus nigra L., aerial parts of Hypericum perforatum L., and roots of Saponaria officinalis (100 g; 70 g; 40 g) exhibited an antiviral effect. It inhibited the reproduction of different strains of influenza virus types A and B, both in vitro and in vivo, and herpes simplex virus type 1, in vitro. 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It inhibited the reproduction of different strains of influenza virus types A and B, both in vitro and in vivo, and herpes simplex virus type 1, in vitro. 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It inhibited the reproduction of different strains of influenza virus types A and B, both <hi rend="italic">in vitro</hi> and <hi rend="italic">in vivo</hi>, and herpes simplex virus type 1, <hi rend="italic">in vitro.</hi> The preparation contains flavonoids, triterpene saponins, phenolic acids, tannins and polysaccharides which could be responsible for its antiviral properties.</p></abstract><textClass><keywords xml:lang="en"><term xml:id="kwd1">antiviral activity of lyophilized plant preparation SHS‐174</term><term xml:id="kwd2"><hi rend="italic">Sambucus nigra</hi></term><term xml:id="kwd3"><hi rend="italic">Hypericum perforatum</hi></term><term xml:id="kwd4"><hi rend="italic">Saponaria officinalis</hi></term></keywords><keywords rend="articleCategory"><term>Article</term></keywords><keywords rend="tocHeading1"><term>Articles</term></keywords></textClass><langUsage><language ident="en"></language></langUsage></profileDesc><revisionDesc><change when="2019-12-20" who="#istex" xml:id="pub2tei">formatting</change></revisionDesc></teiHeader></istex:fulltextTEI><json:item><extension>txt</extension><original>false</original><mimetype>text/plain</mimetype><uri>https://api.istex.fr/ark:/67375/WNG-5BLF2D1X-2/fulltext.txt</uri></json:item></fulltext><metadata><istex:metadataXml wicri:clean="Wiley, elements deleted: body"><istex:xmlDeclaration>version="1.0" encoding="UTF-8" standalone="yes"</istex:xmlDeclaration><istex:document><component version="2.0" type="serialArticle" xml:lang="en"><header><publicationMeta level="product"><publisherInfo><publisherName>John Wiley & Sons, Ltd.</publisherName><publisherLoc>Chichester, UK</publisherLoc></publisherInfo><doi registered="yes">10.1002/(ISSN)1099-1573</doi><issn type="print">0951-418X</issn><issn type="electronic">1099-1573</issn><idGroup><id type="product" value="PTR"></id></idGroup><titleGroup><title type="main" xml:lang="en" sort="PHYTOTHERAPY RESEARCH">Phytotherapy Research</title><title type="short">Phytother. Res.</title></titleGroup></publicationMeta><publicationMeta level="part" position="30"><doi origin="wiley" registered="yes">10.1002/ptr.v4:3</doi><numberingGroup><numbering type="journalVolume" number="4">4</numbering><numbering type="journalIssue">3</numbering></numberingGroup><coverDate startDate="1990-06">June 1990</coverDate></publicationMeta><publicationMeta level="unit" type="article" position="5" status="forIssue"><doi origin="wiley" registered="yes">10.1002/ptr.2650040305</doi><idGroup><id type="unit" value="PTR2650040305"></id></idGroup><countGroup><count type="pageTotal" number="4"></count></countGroup><titleGroup><title type="articleCategory">Article</title><title type="tocHeading1">Articles</title></titleGroup><copyright ownership="publisher">Copyright © 1990 John Wiley & Sons, Ltd.</copyright><eventGroup><event type="manuscriptReceived" date="1989-09-05"></event><event type="manuscriptAccepted" date="1989-12-19"></event><event type="firstOnline" date="2006-01-11"></event><event type="publishedOnlineFinalForm" date="2006-01-11"></event><event type="xmlConverted" agent="Converter:JWSART34_TO_WML3G version:2.3.6 mode:FullText source:HeaderRef result:HeaderRef" date="2010-04-20"></event><event type="xmlConverted" agent="Converter:WILEY_ML3G_TO_WILEY_ML3GV2 version:3.8.8" date="2014-02-07"></event><event type="xmlConverted" agent="Converter:WML3G_To_WML3G version:4.1.7 mode:FullText,remove_FC" date="2014-11-03"></event></eventGroup><numberingGroup><numbering type="pageFirst">97</numbering><numbering type="pageLast">100</numbering></numberingGroup><correspondenceTo>Department of Virology, Institute of Microbiology, Medical Academy, 18 Czysta Street, Cracow, Poland</correspondenceTo><linkGroup><link type="toTypesetVersion" href="file:PTR.PTR2650040305.pdf"></link></linkGroup></publicationMeta><contentMeta><countGroup><count type="figureTotal" number="2"></count><count type="tableTotal" number="2"></count><count type="referenceTotal" number="18"></count></countGroup><titleGroup><title type="main" xml:lang="en">Antiviral activity of the infusion (SHS‐174) from flowers of <i>Sambucus nigra</i> L., aerial parts of <i>Hypericum perforatum</i> L., and roots of <i>Saponaria officinalis</i> L. against influenza and herpes simplex viruses</title><title type="short" xml:lang="en">ANTIVIRAL ACTIVITY OF LYOPHILIZED PLANT PREPARATION SH‐174</title></titleGroup><creators><creator xml:id="au1" creatorRole="author" affiliationRef="#af1"><personName><givenNames>Julia</givenNames><familyName>Serkedjieva</familyName></personName></creator><creator xml:id="au2" creatorRole="author" affiliationRef="#af1"><personName><givenNames>Nadia</givenNames><familyName>Manolova</familyName></personName></creator><creator xml:id="au3" creatorRole="author" affiliationRef="#af2" corresponding="yes"><personName><givenNames>Izabella</givenNames><familyName>Zgórniak‐Nowosielska</familyName></personName></creator><creator xml:id="au4" creatorRole="author" affiliationRef="#af2"><personName><givenNames>Barbara</givenNames><familyName>Zawilińska</familyName></personName></creator><creator xml:id="au5" creatorRole="author" affiliationRef="#af3"><personName><givenNames>Jan</givenNames><familyName>Grzybek</familyName></personName></creator></creators><affiliationGroup><affiliation xml:id="af1" countryCode="BG" type="organization"><unparsedAffiliation>Institute of Microbiology, Bulgarian Academy of Sciences, Sofia, Bulgaria</unparsedAffiliation></affiliation><affiliation xml:id="af2" countryCode="PL" type="organization"><unparsedAffiliation>Department of Virology, Institute of Microbiology, Medical Academy, 18 Czysta Street, Cracow, Poland</unparsedAffiliation></affiliation><affiliation xml:id="af3" countryCode="PL" type="organization"><unparsedAffiliation>Department of Pharmaceutical Botany, Medical Academy, 16 Krupnicza Street, Cracow, Poland</unparsedAffiliation></affiliation></affiliationGroup><keywordGroup xml:lang="en" type="author"><keyword xml:id="kwd1">antiviral activity of lyophilized plant preparation SHS‐174</keyword><keyword xml:id="kwd2"><i>Sambucus nigra</i></keyword><keyword xml:id="kwd3"><i>Hypericum perforatum</i></keyword><keyword xml:id="kwd4"><i>Saponaria officinalis</i></keyword></keywordGroup><fundingInfo><fundingAgency>Academies of Sciences</fundingAgency><fundingNumber>CPBP No. 04.02 1.6.3</fundingNumber></fundingInfo><abstractGroup><abstract type="main" xml:lang="en"><title type="main">Abstract</title><p>The SHS‐174 preparation, a lyophilized infusion from flowers of <i>Sambucus nigra</i> L., aerial parts of <i>Hypericum perforatum</i> L., and roots of <i>Saponaria officinalis</i> (100 g; 70 g; 40 g) exhibited an antiviral effect. It inhibited the reproduction of different strains of influenza virus types A and B, both <i>in vitro</i> and <i>in vivo</i>, and herpes simplex virus type 1, <i>in vitro.</i> The preparation contains flavonoids, triterpene saponins, phenolic acids, tannins and polysaccharides which could be responsible for its antiviral properties.</p></abstract></abstractGroup></contentMeta></header></component></istex:document></istex:metadataXml><mods version="3.6"><titleInfo lang="en"><title>Antiviral activity of the infusion (SHS‐174) from flowers of Sambucus nigra L., aerial parts of Hypericum perforatum L., and roots of Saponaria officinalis L. against influenza and herpes simplex viruses</title></titleInfo><titleInfo type="abbreviated" lang="en"><title>ANTIVIRAL ACTIVITY OF LYOPHILIZED PLANT PREPARATION SH‐174</title></titleInfo><titleInfo type="alternative" contentType="CDATA" lang="en"><title>Antiviral activity of the infusion (SHS‐174) from flowers of Sambucus nigra L., aerial parts of Hypericum perforatum L., and roots of Saponaria officinalis L. against influenza and herpes simplex viruses</title></titleInfo><name type="personal"><namePart type="given">Julia</namePart><namePart type="family">Serkedjieva</namePart><affiliation>Institute of Microbiology, Bulgarian Academy of Sciences, Sofia, Bulgaria</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Nadia</namePart><namePart type="family">Manolova</namePart><affiliation>Institute of Microbiology, Bulgarian Academy of Sciences, Sofia, Bulgaria</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Izabella</namePart><namePart type="family">Zgórniak‐Nowosielska</namePart><affiliation>Department of Virology, Institute of Microbiology, Medical Academy, 18 Czysta Street, Cracow, Poland</affiliation><affiliation>Correspondence address: Department of Virology, Institute of Microbiology, Medical Academy, 18 Czysta Street, Cracow, Poland</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Barbara</namePart><namePart type="family">Zawilińska</namePart><affiliation>Department of Virology, Institute of Microbiology, Medical Academy, 18 Czysta Street, Cracow, Poland</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Jan</namePart><namePart type="family">Grzybek</namePart><affiliation>Department of Pharmaceutical Botany, Medical Academy, 16 Krupnicza Street, Cracow, Poland</affiliation><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre type="article" displayLabel="article" authority="ISTEX" authorityURI="https://content-type.data.istex.fr" valueURI="https://content-type.data.istex.fr/ark:/67375/XTP-6N5SZHKN-D">article</genre><originInfo><publisher>John Wiley & Sons, Ltd.</publisher><place><placeTerm type="text">Chichester, UK</placeTerm></place><dateIssued encoding="w3cdtf">1990-06</dateIssued><dateCaptured encoding="w3cdtf">1989-09-05</dateCaptured><dateValid encoding="w3cdtf">1989-12-19</dateValid><copyrightDate encoding="w3cdtf">1990</copyrightDate></originInfo><language><languageTerm type="code" authority="rfc3066">en</languageTerm><languageTerm type="code" authority="iso639-2b">eng</languageTerm></language><physicalDescription><extent unit="figures">2</extent><extent unit="tables">2</extent><extent unit="references">18</extent></physicalDescription><abstract lang="en">The SHS‐174 preparation, a lyophilized infusion from flowers of Sambucus nigra L., aerial parts of Hypericum perforatum L., and roots of Saponaria officinalis (100 g; 70 g; 40 g) exhibited an antiviral effect. It inhibited the reproduction of different strains of influenza virus types A and B, both in vitro and in vivo, and herpes simplex virus type 1, in vitro. The preparation contains flavonoids, triterpene saponins, phenolic acids, tannins and polysaccharides which could be responsible for its antiviral properties.</abstract><note type="funding">Academies of Sciences - CPBP No. 04.02 1.6.3; </note><subject lang="en"><genre>keywords</genre><topic>antiviral activity of lyophilized plant preparation SHS‐174</topic><topic>Sambucus nigra</topic><topic>Hypericum perforatum</topic><topic>Saponaria officinalis</topic></subject><relatedItem type="host"><titleInfo><title>Phytotherapy Research</title></titleInfo><titleInfo type="abbreviated"><title>Phytother. 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