H2N2V1, Hal, Checkpoint, bibRecord, 000051

Post authorisation influenza vaccine effectiveness against influenza associated hospitalisation with laboratory confirmed influenza among adults in Europe

Identifieur interne : 000051 ( Hal/Checkpoint ); précédent : 000050; suivant : 000052

Post authorisation influenza vaccine effectiveness against influenza associated hospitalisation with laboratory confirmed influenza among adults in Europe

Auteurs : Marc Rondy [France]

Source :

RBID : Hal:tel-01635265

Descripteurs français

mix :
- Adultes, Cas-témoins, Efficacité vaccinale, Grippe, Épidémiologie.
Wicri :
- topic : épidémiologie.

English descriptors

mix :
- Adults, Case-control, Epidemiology, Influenza, Vaccine effectiveness.

Abstract

Our objective was to measure seasonal influenza vaccine effectiveness (IVE) against hospitalisation with laboratory-confirmed influenza in Europe among adults. Between 2011 and 2017, we coordinated a multicenter case-control study in 29 hospitals in 12 countries. We pooled and analysed the data after every season. Between 2011-12 and 2016-17, we recruited 3436 influenza cases and 5969 controls. Pooled across seasons, IVE against any influenza was 26%; 40% patients aged 18-64 yeas, 25% among those aged 65-79 years, and 23% among those aged ≥80 years. Season specific IVE ranged between 15% in 2016-17 and 44% in 2013-14. IVE was particularly low among elderly in seasons dominated by the A(H3N2) viruses; it was 10% in 2011-12 and 2016-17 in people aged ≥80 years. Our results suggest a low to moderate IVE against influenza hospitalisation in adults. Evaluating complementary prevention options, such as prophylactic antiviral use, vaccination of health care workers and non-pharmaceutical interventions should be a priority.

Url:

https://tel.archives-ouvertes.fr/tel-01635265

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Hal:tel-01635265

Le document en format XML

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<title xml:lang="fr">Efficacité post autorisation de mise sur le marché de la vaccination antigrippale saisonnière contre l’hospitalisation avec une grippe confirmée virologiquement chez l’adulte en Europe</title>
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<front><div type="abstract" xml:lang="en">              <p>Our objective was to measure seasonal influenza vaccine effectiveness (IVE) against hospitalisation with laboratory-confirmed influenza in Europe among adults. Between 2011 and 2017, we coordinated a multicenter case-control study in 29 hospitals in 12 countries. We pooled and analysed the data after every season. Between 2011-12 and 2016-17, we recruited 3436 influenza cases and 5969 controls. Pooled across seasons, IVE against any influenza was 26%; 40% patients aged 18-64 yeas, 25% among those aged 65-79 years, and 23% among those aged ≥80 years. Season specific IVE ranged between 15% in 2016-17 and 44% in 2013-14. IVE was particularly low among elderly in seasons dominated by the A(H3N2) viruses; it was 10% in 2011-12 and 2016-17 in people aged ≥80 years. Our results suggest a low to moderate IVE against influenza hospitalisation in adults. Evaluating complementary prevention options, such as prophylactic antiviral use, vaccination of health care workers and non-pharmaceutical interventions should be a priority.</p>
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            <title xml:lang="fr">Efficacité post autorisation de mise sur le marché de la vaccination antigrippale saisonnière contre l’hospitalisation avec une grippe confirmée virologiquement chez l’adulte en Europe</title>
            <author role="aut">              <persName>                <forename type="first">Marc</forename>
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                <title xml:lang="fr">Efficacité post autorisation de mise sur le marché de la vaccination antigrippale saisonnière contre l’hospitalisation avec une grippe confirmée virologiquement chez l’adulte en Europe</title>
                <author role="aut">                  <persName>                    <forename type="first">Marc</forename>
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            <abstract xml:lang="en">              <p>Our objective was to measure seasonal influenza vaccine effectiveness (IVE) against hospitalisation with laboratory-confirmed influenza in Europe among adults. Between 2011 and 2017, we coordinated a multicenter case-control study in 29 hospitals in 12 countries. We pooled and analysed the data after every season. Between 2011-12 and 2016-17, we recruited 3436 influenza cases and 5969 controls. Pooled across seasons, IVE against any influenza was 26%; 40% patients aged 18-64 yeas, 25% among those aged 65-79 years, and 23% among those aged ≥80 years. Season specific IVE ranged between 15% in 2016-17 and 44% in 2013-14. IVE was particularly low among elderly in seasons dominated by the A(H3N2) viruses; it was 10% in 2011-12 and 2016-17 in people aged ≥80 years. Our results suggest a low to moderate IVE against influenza hospitalisation in adults. Evaluating complementary prevention options, such as prophylactic antiviral use, vaccination of health care workers and non-pharmaceutical interventions should be a priority.</p>
            </abstract>
            <abstract xml:lang="fr">              <p>Notre objectif était de mesurer chez les adultes en Europe l’efficacité des vaccins (EV) anti-grippaux saisonniers contre l’hospitalisation avec une grippe confirmée en laboratoire. Nous avons coordonné une étude cas-témoins multicentrique dans 29 hôpitaux de 12 pays entre 2011 et 2017. Nous avons fait une analyse des données groupées lors de chaque saison grippale. Entre 2011-12 et 2016-17, nous avons recruté 3436 cas de grippe et 5969 témoins. L’EV tous virus confondus était de 26% ; elle était de 40% chez les 18-64 ans, 25% chez les 65-79 ans et 23% chez les 80 ans et plus. Par saison, l’EV variait entre 15% en 2016-17 et 44% en 2013-14. L’EV était particulièrement basse chez les seniors lors des saisons grippales dominées par le sous-type de grippe A(H3N2), atteignant 10% en 2011-12 et 2016-17 chez les personnes âgées de 80 ans et plus. Nos résultats suggèrent une EV faible à modérée contre la grippe hospitalisée chez l’adulte. Le renforcement et l’évaluation de modes de prévention complémentaires, tels que l’usage prophylactique d’antiviraux, la vaccination du personnel soignant et les approches non-pharmaceutiques (masque, hygiène des mains) devraient être une priorité.</p>
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Post authorisation influenza vaccine effectiveness against influenza associated hospitalisation with laboratory confirmed influenza among adults in Europe

Post authorisation influenza vaccine effectiveness against influenza associated hospitalisation with laboratory confirmed influenza among adults in Europe

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri