Co-circulation of two genetically distinct sub-groups of A/H3N2 influenza strains during the 2006-2007 epidemic season in Corsica Island, France.
Identifieur interne : 000214 ( France/Analysis ); précédent : 000213; suivant : 000215Co-circulation of two genetically distinct sub-groups of A/H3N2 influenza strains during the 2006-2007 epidemic season in Corsica Island, France.
Auteurs : Alessandra Falchi [France] ; Laurent Varesi [France] ; Christophe Arena [France] ; Nicolas Leveque [France] ; Fanny Renois [France] ; Thierry Blanchon [France] ; Jean Pierre Amoros [France] ; Laurent Andreoletti [France]Source :
Abstract
BACKGROUND: Influenza virus is one of the major viral respiratory pathogens infecting human beings. OBJECTIVES: To determine the influenza A virus variants responsible for the 2006-2007 epidemic season in Corsica Island, France. STUDY DESIGN: Of 134 nasal samples of adult patients tested by culture and RT-PCR assays, 85 influenza A strains were identified; 81 (95%) were sub-typed as A/H3N2 and 4 (5%) were sub-typed as A/H1N1. RESULTS: All of the HA sequences of the A/H3N2 viruses circulating in Corsica Island appeared to be closely related to the A/Wisconsin/67/2005 vaccine strain and segregated into two sub-groups that were genetically distinct from other viruses circulating in other countries during 2006/2007. One of these sub-groups was distinguished by the substitution H156Q whereas the second demonstrated at least one of the 3 other additional mutations (R142G, L157S and K173E) common to the HA1 sequence of A/Nepal/921/2006 reference strain. Among the 14 strains of this second sub-group, 10 viral strains had been isolated from vaccinated adult patients. CONCLUSION: These findings suggest that a prospective analysis of the HA sequences of influenza isolates may allow an early detection of newly evolved variants with potential epidemiological inference.
Url:
DOI: 10.1016/j.jcv.2009.05.004
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Hal, to step Corpus: 000038
- to stream Hal, to step Curation: 000038
- to stream Hal, to step Checkpoint: 000292
- to stream Main, to step Merge: 001015
- to stream Main, to step Curation: 001007
- to stream Main, to step Exploration: 001007
- to stream France, to step Extraction: 000214
Links to Exploration step
Hal:hal-00628455Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Co-circulation of two genetically distinct sub-groups of A/H3N2 influenza strains during the 2006-2007 epidemic season in Corsica Island, France.</title>
<author><name sortKey="Falchi, Alessandra" sort="Falchi, Alessandra" uniqKey="Falchi A" first="Alessandra" last="Falchi">Alessandra Falchi</name>
<affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-3065" status="OLD"> <orgName>Epidémiologie des maladies infectieuses et modélisation</orgName>
<orgName type="acronym">ESIM</orgName>
<desc> <address> <addrLine>Faculte de Médecine Saint-Antoine 27, Rue Chaligny 75571 Paris Cedex 12</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.u707.jussieu.fr</ref>
</desc>
<listRelation> <relation active="#struct-93591" type="direct"></relation>
<relation name="U707" active="#struct-303623" type="direct"></relation>
</listRelation>
<tutelles><tutelle active="#struct-93591" type="direct"><org type="institution" xml:id="struct-93591" status="OLD"> <orgName>Université Pierre et Marie Curie - Paris 6</orgName>
<orgName type="acronym">UPMC</orgName>
<date type="end">2017-12-31</date>
<desc> <address> <addrLine>4 place Jussieu - 75005 Paris</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.upmc.fr/</ref>
</desc>
</org>
</tutelle>
<tutelle name="U707" active="#struct-303623" type="direct"><org type="institution" xml:id="struct-303623" status="VALID"> <idno type="IdRef">026388278</idno>
<orgName>Institut National de la Santé et de la Recherche Médicale</orgName>
<orgName type="acronym">INSERM</orgName>
<desc> <address> <addrLine>101, rue de Tolbiac, 75013 Paris </addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.inserm.fr</ref>
</desc>
</org>
</tutelle>
</tutelles>
</hal:affiliation>
<country>France</country>
</affiliation>
</author>
<author><name sortKey="Varesi, Laurent" sort="Varesi, Laurent" uniqKey="Varesi L" first="Laurent" last="Varesi">Laurent Varesi</name>
<affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-843" status="VALID"> <orgName>Sciences pour l'environnement</orgName>
<orgName type="acronym">SPE</orgName>
<desc> <address> <addrLine>Adresse 1 (principale): Campus GRIMALDI, Bâtiment PPDB, 20250 Corte Adresse 2: Lieu dit Vignola, route des sanguinaires, 20000 Ajaccio</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://spe.univ-corse.fr</ref>
</desc>
<listRelation> <relation active="#struct-300269" type="direct"></relation>
<relation name="UMR6134" active="#struct-441569" type="direct"></relation>
</listRelation>
<tutelles><tutelle active="#struct-300269" type="direct"><org type="institution" xml:id="struct-300269" status="VALID"> <orgName>Université Pascal Paoli</orgName>
<orgName type="acronym">UPP</orgName>
<desc> <address> <country key="FR"></country>
</address>
<ref type="url">https://www.universita.corsica/fr/</ref>
</desc>
</org>
</tutelle>
<tutelle name="UMR6134" active="#struct-441569" type="direct"><org type="institution" xml:id="struct-441569" status="VALID"> <idno type="IdRef">02636817X</idno>
<idno type="ISNI">0000000122597504</idno>
<orgName>Centre National de la Recherche Scientifique</orgName>
<orgName type="acronym">CNRS</orgName>
<date type="start">1939-10-19</date>
<desc> <address> <country key="FR"></country>
</address>
<ref type="url">http://www.cnrs.fr/</ref>
</desc>
</org>
</tutelle>
</tutelles>
</hal:affiliation>
<country>France</country>
</affiliation>
</author>
<author><name sortKey="Arena, Christophe" sort="Arena, Christophe" uniqKey="Arena C" first="Christophe" last="Arena">Christophe Arena</name>
<affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-3065" status="OLD"> <orgName>Epidémiologie des maladies infectieuses et modélisation</orgName>
<orgName type="acronym">ESIM</orgName>
<desc> <address> <addrLine>Faculte de Médecine Saint-Antoine 27, Rue Chaligny 75571 Paris Cedex 12</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.u707.jussieu.fr</ref>
</desc>
<listRelation> <relation active="#struct-93591" type="direct"></relation>
<relation name="U707" active="#struct-303623" type="direct"></relation>
</listRelation>
<tutelles><tutelle active="#struct-93591" type="direct"><org type="institution" xml:id="struct-93591" status="OLD"> <orgName>Université Pierre et Marie Curie - Paris 6</orgName>
<orgName type="acronym">UPMC</orgName>
<date type="end">2017-12-31</date>
<desc> <address> <addrLine>4 place Jussieu - 75005 Paris</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.upmc.fr/</ref>
</desc>
</org>
</tutelle>
<tutelle name="U707" active="#struct-303623" type="direct"><org type="institution" xml:id="struct-303623" status="VALID"> <idno type="IdRef">026388278</idno>
<orgName>Institut National de la Santé et de la Recherche Médicale</orgName>
<orgName type="acronym">INSERM</orgName>
<desc> <address> <addrLine>101, rue de Tolbiac, 75013 Paris </addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.inserm.fr</ref>
</desc>
</org>
</tutelle>
</tutelles>
</hal:affiliation>
<country>France</country>
</affiliation>
</author>
<author><name sortKey="Leveque, Nicolas" sort="Leveque, Nicolas" uniqKey="Leveque N" first="Nicolas" last="Leveque">Nicolas Leveque</name>
<affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-7569" status="VALID"> <orgName>Université de Reims Champagne-Ardenne</orgName>
<orgName type="acronym">URCA</orgName>
<desc> <address> <addrLine>9 boulevard de la Paix - CS 60005 - 51724 Reims cedex</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.univ-reims.fr/</ref>
</desc>
</hal:affiliation>
<country>France</country>
</affiliation>
</author>
<author><name sortKey="Renois, Fanny" sort="Renois, Fanny" uniqKey="Renois F" first="Fanny" last="Renois">Fanny Renois</name>
<affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-7569" status="VALID"> <orgName>Université de Reims Champagne-Ardenne</orgName>
<orgName type="acronym">URCA</orgName>
<desc> <address> <addrLine>9 boulevard de la Paix - CS 60005 - 51724 Reims cedex</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.univ-reims.fr/</ref>
</desc>
</hal:affiliation>
<country>France</country>
</affiliation>
</author>
<author><name sortKey="Blanchon, Thierry" sort="Blanchon, Thierry" uniqKey="Blanchon T" first="Thierry" last="Blanchon">Thierry Blanchon</name>
<affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-3065" status="OLD"> <orgName>Epidémiologie des maladies infectieuses et modélisation</orgName>
<orgName type="acronym">ESIM</orgName>
<desc> <address> <addrLine>Faculte de Médecine Saint-Antoine 27, Rue Chaligny 75571 Paris Cedex 12</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.u707.jussieu.fr</ref>
</desc>
<listRelation> <relation active="#struct-93591" type="direct"></relation>
<relation name="U707" active="#struct-303623" type="direct"></relation>
</listRelation>
<tutelles><tutelle active="#struct-93591" type="direct"><org type="institution" xml:id="struct-93591" status="OLD"> <orgName>Université Pierre et Marie Curie - Paris 6</orgName>
<orgName type="acronym">UPMC</orgName>
<date type="end">2017-12-31</date>
<desc> <address> <addrLine>4 place Jussieu - 75005 Paris</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.upmc.fr/</ref>
</desc>
</org>
</tutelle>
<tutelle name="U707" active="#struct-303623" type="direct"><org type="institution" xml:id="struct-303623" status="VALID"> <idno type="IdRef">026388278</idno>
<orgName>Institut National de la Santé et de la Recherche Médicale</orgName>
<orgName type="acronym">INSERM</orgName>
<desc> <address> <addrLine>101, rue de Tolbiac, 75013 Paris </addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.inserm.fr</ref>
</desc>
</org>
</tutelle>
</tutelles>
</hal:affiliation>
<country>France</country>
</affiliation>
</author>
<author><name sortKey="Amoros, Jean Pierre" sort="Amoros, Jean Pierre" uniqKey="Amoros J" first="Jean Pierre" last="Amoros">Jean Pierre Amoros</name>
<affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-3065" status="OLD"> <orgName>Epidémiologie des maladies infectieuses et modélisation</orgName>
<orgName type="acronym">ESIM</orgName>
<desc> <address> <addrLine>Faculte de Médecine Saint-Antoine 27, Rue Chaligny 75571 Paris Cedex 12</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.u707.jussieu.fr</ref>
</desc>
<listRelation> <relation active="#struct-93591" type="direct"></relation>
<relation name="U707" active="#struct-303623" type="direct"></relation>
</listRelation>
<tutelles><tutelle active="#struct-93591" type="direct"><org type="institution" xml:id="struct-93591" status="OLD"> <orgName>Université Pierre et Marie Curie - Paris 6</orgName>
<orgName type="acronym">UPMC</orgName>
<date type="end">2017-12-31</date>
<desc> <address> <addrLine>4 place Jussieu - 75005 Paris</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.upmc.fr/</ref>
</desc>
</org>
</tutelle>
<tutelle name="U707" active="#struct-303623" type="direct"><org type="institution" xml:id="struct-303623" status="VALID"> <idno type="IdRef">026388278</idno>
<orgName>Institut National de la Santé et de la Recherche Médicale</orgName>
<orgName type="acronym">INSERM</orgName>
<desc> <address> <addrLine>101, rue de Tolbiac, 75013 Paris </addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.inserm.fr</ref>
</desc>
</org>
</tutelle>
</tutelles>
</hal:affiliation>
<country>France</country>
</affiliation>
</author>
<author><name sortKey="Andreoletti, Laurent" sort="Andreoletti, Laurent" uniqKey="Andreoletti L" first="Laurent" last="Andreoletti">Laurent Andreoletti</name>
<affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-7569" status="VALID"> <orgName>Université de Reims Champagne-Ardenne</orgName>
<orgName type="acronym">URCA</orgName>
<desc> <address> <addrLine>9 boulevard de la Paix - CS 60005 - 51724 Reims cedex</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.univ-reims.fr/</ref>
</desc>
</hal:affiliation>
<country>France</country>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">HAL</idno>
<idno type="RBID">Hal:hal-00628455</idno>
<idno type="halId">hal-00628455</idno>
<idno type="halUri">https://hal.archives-ouvertes.fr/hal-00628455</idno>
<idno type="url">https://hal.archives-ouvertes.fr/hal-00628455</idno>
<idno type="doi">10.1016/j.jcv.2009.05.004</idno>
<date when="2009-07">2009-07</date>
<idno type="wicri:Area/Hal/Corpus">000038</idno>
<idno type="wicri:Area/Hal/Curation">000038</idno>
<idno type="wicri:Area/Hal/Checkpoint">000292</idno>
<idno type="wicri:explorRef" wicri:stream="Hal" wicri:step="Checkpoint">000292</idno>
<idno type="wicri:Area/Main/Merge">001015</idno>
<idno type="wicri:Area/Main/Curation">001007</idno>
<idno type="wicri:Area/Main/Exploration">001007</idno>
<idno type="wicri:Area/France/Extraction">000214</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en">Co-circulation of two genetically distinct sub-groups of A/H3N2 influenza strains during the 2006-2007 epidemic season in Corsica Island, France.</title>
<author><name sortKey="Falchi, Alessandra" sort="Falchi, Alessandra" uniqKey="Falchi A" first="Alessandra" last="Falchi">Alessandra Falchi</name>
<affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-3065" status="OLD"> <orgName>Epidémiologie des maladies infectieuses et modélisation</orgName>
<orgName type="acronym">ESIM</orgName>
<desc> <address> <addrLine>Faculte de Médecine Saint-Antoine 27, Rue Chaligny 75571 Paris Cedex 12</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.u707.jussieu.fr</ref>
</desc>
<listRelation> <relation active="#struct-93591" type="direct"></relation>
<relation name="U707" active="#struct-303623" type="direct"></relation>
</listRelation>
<tutelles><tutelle active="#struct-93591" type="direct"><org type="institution" xml:id="struct-93591" status="OLD"> <orgName>Université Pierre et Marie Curie - Paris 6</orgName>
<orgName type="acronym">UPMC</orgName>
<date type="end">2017-12-31</date>
<desc> <address> <addrLine>4 place Jussieu - 75005 Paris</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.upmc.fr/</ref>
</desc>
</org>
</tutelle>
<tutelle name="U707" active="#struct-303623" type="direct"><org type="institution" xml:id="struct-303623" status="VALID"> <idno type="IdRef">026388278</idno>
<orgName>Institut National de la Santé et de la Recherche Médicale</orgName>
<orgName type="acronym">INSERM</orgName>
<desc> <address> <addrLine>101, rue de Tolbiac, 75013 Paris </addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.inserm.fr</ref>
</desc>
</org>
</tutelle>
</tutelles>
</hal:affiliation>
<country>France</country>
</affiliation>
</author>
<author><name sortKey="Varesi, Laurent" sort="Varesi, Laurent" uniqKey="Varesi L" first="Laurent" last="Varesi">Laurent Varesi</name>
<affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-843" status="VALID"> <orgName>Sciences pour l'environnement</orgName>
<orgName type="acronym">SPE</orgName>
<desc> <address> <addrLine>Adresse 1 (principale): Campus GRIMALDI, Bâtiment PPDB, 20250 Corte Adresse 2: Lieu dit Vignola, route des sanguinaires, 20000 Ajaccio</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://spe.univ-corse.fr</ref>
</desc>
<listRelation> <relation active="#struct-300269" type="direct"></relation>
<relation name="UMR6134" active="#struct-441569" type="direct"></relation>
</listRelation>
<tutelles><tutelle active="#struct-300269" type="direct"><org type="institution" xml:id="struct-300269" status="VALID"> <orgName>Université Pascal Paoli</orgName>
<orgName type="acronym">UPP</orgName>
<desc> <address> <country key="FR"></country>
</address>
<ref type="url">https://www.universita.corsica/fr/</ref>
</desc>
</org>
</tutelle>
<tutelle name="UMR6134" active="#struct-441569" type="direct"><org type="institution" xml:id="struct-441569" status="VALID"> <idno type="IdRef">02636817X</idno>
<idno type="ISNI">0000000122597504</idno>
<orgName>Centre National de la Recherche Scientifique</orgName>
<orgName type="acronym">CNRS</orgName>
<date type="start">1939-10-19</date>
<desc> <address> <country key="FR"></country>
</address>
<ref type="url">http://www.cnrs.fr/</ref>
</desc>
</org>
</tutelle>
</tutelles>
</hal:affiliation>
<country>France</country>
</affiliation>
</author>
<author><name sortKey="Arena, Christophe" sort="Arena, Christophe" uniqKey="Arena C" first="Christophe" last="Arena">Christophe Arena</name>
<affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-3065" status="OLD"> <orgName>Epidémiologie des maladies infectieuses et modélisation</orgName>
<orgName type="acronym">ESIM</orgName>
<desc> <address> <addrLine>Faculte de Médecine Saint-Antoine 27, Rue Chaligny 75571 Paris Cedex 12</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.u707.jussieu.fr</ref>
</desc>
<listRelation> <relation active="#struct-93591" type="direct"></relation>
<relation name="U707" active="#struct-303623" type="direct"></relation>
</listRelation>
<tutelles><tutelle active="#struct-93591" type="direct"><org type="institution" xml:id="struct-93591" status="OLD"> <orgName>Université Pierre et Marie Curie - Paris 6</orgName>
<orgName type="acronym">UPMC</orgName>
<date type="end">2017-12-31</date>
<desc> <address> <addrLine>4 place Jussieu - 75005 Paris</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.upmc.fr/</ref>
</desc>
</org>
</tutelle>
<tutelle name="U707" active="#struct-303623" type="direct"><org type="institution" xml:id="struct-303623" status="VALID"> <idno type="IdRef">026388278</idno>
<orgName>Institut National de la Santé et de la Recherche Médicale</orgName>
<orgName type="acronym">INSERM</orgName>
<desc> <address> <addrLine>101, rue de Tolbiac, 75013 Paris </addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.inserm.fr</ref>
</desc>
</org>
</tutelle>
</tutelles>
</hal:affiliation>
<country>France</country>
</affiliation>
</author>
<author><name sortKey="Leveque, Nicolas" sort="Leveque, Nicolas" uniqKey="Leveque N" first="Nicolas" last="Leveque">Nicolas Leveque</name>
<affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-7569" status="VALID"> <orgName>Université de Reims Champagne-Ardenne</orgName>
<orgName type="acronym">URCA</orgName>
<desc> <address> <addrLine>9 boulevard de la Paix - CS 60005 - 51724 Reims cedex</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.univ-reims.fr/</ref>
</desc>
</hal:affiliation>
<country>France</country>
</affiliation>
</author>
<author><name sortKey="Renois, Fanny" sort="Renois, Fanny" uniqKey="Renois F" first="Fanny" last="Renois">Fanny Renois</name>
<affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-7569" status="VALID"> <orgName>Université de Reims Champagne-Ardenne</orgName>
<orgName type="acronym">URCA</orgName>
<desc> <address> <addrLine>9 boulevard de la Paix - CS 60005 - 51724 Reims cedex</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.univ-reims.fr/</ref>
</desc>
</hal:affiliation>
<country>France</country>
</affiliation>
</author>
<author><name sortKey="Blanchon, Thierry" sort="Blanchon, Thierry" uniqKey="Blanchon T" first="Thierry" last="Blanchon">Thierry Blanchon</name>
<affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-3065" status="OLD"> <orgName>Epidémiologie des maladies infectieuses et modélisation</orgName>
<orgName type="acronym">ESIM</orgName>
<desc> <address> <addrLine>Faculte de Médecine Saint-Antoine 27, Rue Chaligny 75571 Paris Cedex 12</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.u707.jussieu.fr</ref>
</desc>
<listRelation> <relation active="#struct-93591" type="direct"></relation>
<relation name="U707" active="#struct-303623" type="direct"></relation>
</listRelation>
<tutelles><tutelle active="#struct-93591" type="direct"><org type="institution" xml:id="struct-93591" status="OLD"> <orgName>Université Pierre et Marie Curie - Paris 6</orgName>
<orgName type="acronym">UPMC</orgName>
<date type="end">2017-12-31</date>
<desc> <address> <addrLine>4 place Jussieu - 75005 Paris</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.upmc.fr/</ref>
</desc>
</org>
</tutelle>
<tutelle name="U707" active="#struct-303623" type="direct"><org type="institution" xml:id="struct-303623" status="VALID"> <idno type="IdRef">026388278</idno>
<orgName>Institut National de la Santé et de la Recherche Médicale</orgName>
<orgName type="acronym">INSERM</orgName>
<desc> <address> <addrLine>101, rue de Tolbiac, 75013 Paris </addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.inserm.fr</ref>
</desc>
</org>
</tutelle>
</tutelles>
</hal:affiliation>
<country>France</country>
</affiliation>
</author>
<author><name sortKey="Amoros, Jean Pierre" sort="Amoros, Jean Pierre" uniqKey="Amoros J" first="Jean Pierre" last="Amoros">Jean Pierre Amoros</name>
<affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-3065" status="OLD"> <orgName>Epidémiologie des maladies infectieuses et modélisation</orgName>
<orgName type="acronym">ESIM</orgName>
<desc> <address> <addrLine>Faculte de Médecine Saint-Antoine 27, Rue Chaligny 75571 Paris Cedex 12</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.u707.jussieu.fr</ref>
</desc>
<listRelation> <relation active="#struct-93591" type="direct"></relation>
<relation name="U707" active="#struct-303623" type="direct"></relation>
</listRelation>
<tutelles><tutelle active="#struct-93591" type="direct"><org type="institution" xml:id="struct-93591" status="OLD"> <orgName>Université Pierre et Marie Curie - Paris 6</orgName>
<orgName type="acronym">UPMC</orgName>
<date type="end">2017-12-31</date>
<desc> <address> <addrLine>4 place Jussieu - 75005 Paris</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.upmc.fr/</ref>
</desc>
</org>
</tutelle>
<tutelle name="U707" active="#struct-303623" type="direct"><org type="institution" xml:id="struct-303623" status="VALID"> <idno type="IdRef">026388278</idno>
<orgName>Institut National de la Santé et de la Recherche Médicale</orgName>
<orgName type="acronym">INSERM</orgName>
<desc> <address> <addrLine>101, rue de Tolbiac, 75013 Paris </addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.inserm.fr</ref>
</desc>
</org>
</tutelle>
</tutelles>
</hal:affiliation>
<country>France</country>
</affiliation>
</author>
<author><name sortKey="Andreoletti, Laurent" sort="Andreoletti, Laurent" uniqKey="Andreoletti L" first="Laurent" last="Andreoletti">Laurent Andreoletti</name>
<affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-7569" status="VALID"> <orgName>Université de Reims Champagne-Ardenne</orgName>
<orgName type="acronym">URCA</orgName>
<desc> <address> <addrLine>9 boulevard de la Paix - CS 60005 - 51724 Reims cedex</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.univ-reims.fr/</ref>
</desc>
</hal:affiliation>
<country>France</country>
</affiliation>
</author>
</analytic>
<idno type="DOI">10.1016/j.jcv.2009.05.004</idno>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass></textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en"> <p>BACKGROUND: Influenza virus is one of the major viral respiratory pathogens infecting human beings. OBJECTIVES: To determine the influenza A virus variants responsible for the 2006-2007 epidemic season in Corsica Island, France. STUDY DESIGN: Of 134 nasal samples of adult patients tested by culture and RT-PCR assays, 85 influenza A strains were identified; 81 (95%) were sub-typed as A/H3N2 and 4 (5%) were sub-typed as A/H1N1. RESULTS: All of the HA sequences of the A/H3N2 viruses circulating in Corsica Island appeared to be closely related to the A/Wisconsin/67/2005 vaccine strain and segregated into two sub-groups that were genetically distinct from other viruses circulating in other countries during 2006/2007. One of these sub-groups was distinguished by the substitution H156Q whereas the second demonstrated at least one of the 3 other additional mutations (R142G, L157S and K173E) common to the HA1 sequence of A/Nepal/921/2006 reference strain. Among the 14 strains of this second sub-group, 10 viral strains had been isolated from vaccinated adult patients. CONCLUSION: These findings suggest that a prospective analysis of the HA sequences of influenza isolates may allow an early detection of newly evolved variants with potential epidemiological inference.</p>
</div>
</front>
</TEI>
<affiliations><list><country><li>France</li>
</country>
</list>
<tree><country name="France"><noRegion><name sortKey="Falchi, Alessandra" sort="Falchi, Alessandra" uniqKey="Falchi A" first="Alessandra" last="Falchi">Alessandra Falchi</name>
</noRegion>
<name sortKey="Amoros, Jean Pierre" sort="Amoros, Jean Pierre" uniqKey="Amoros J" first="Jean Pierre" last="Amoros">Jean Pierre Amoros</name>
<name sortKey="Andreoletti, Laurent" sort="Andreoletti, Laurent" uniqKey="Andreoletti L" first="Laurent" last="Andreoletti">Laurent Andreoletti</name>
<name sortKey="Arena, Christophe" sort="Arena, Christophe" uniqKey="Arena C" first="Christophe" last="Arena">Christophe Arena</name>
<name sortKey="Blanchon, Thierry" sort="Blanchon, Thierry" uniqKey="Blanchon T" first="Thierry" last="Blanchon">Thierry Blanchon</name>
<name sortKey="Leveque, Nicolas" sort="Leveque, Nicolas" uniqKey="Leveque N" first="Nicolas" last="Leveque">Nicolas Leveque</name>
<name sortKey="Renois, Fanny" sort="Renois, Fanny" uniqKey="Renois F" first="Fanny" last="Renois">Fanny Renois</name>
<name sortKey="Varesi, Laurent" sort="Varesi, Laurent" uniqKey="Varesi L" first="Laurent" last="Varesi">Laurent Varesi</name>
</country>
</tree>
</affiliations>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/H2N2V1/Data/France/Analysis
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000214 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/France/Analysis/biblio.hfd -nk 000214 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Sante |area= H2N2V1 |flux= France |étape= Analysis |type= RBID |clé= Hal:hal-00628455 |texte= Co-circulation of two genetically distinct sub-groups of A/H3N2 influenza strains during the 2006-2007 epidemic season in Corsica Island, France. }}
This area was generated with Dilib version V0.6.33. |