GrippePaysBasV1, Main, Exploration, bibRecord, 000061

[Splenomegaly in an Eritrean refugee: the hyper-reactive malaria splenomegaly syndrome.]

Identifieur interne : 000061 ( Main/Exploration ); précédent : 000060; suivant : 000062

[Splenomegaly in an Eritrean refugee: the hyper-reactive malaria splenomegaly syndrome.]

Auteurs : M M Cruijsen [Pays-Bas] ; I J Reuling ; M. Keuter ; R W Sauerwein ; A J Van Der Ven ; Q. De Mast

Source :

Nederlands tijdschrift voor geneeskunde [ 1876-8784 ]

RBID : pubmed:27848905

Descripteurs français

KwdFr :
- Adulte (MeSH), Humains (MeSH), Hépatomégalie (MeSH), Mâle (MeSH), Paludisme (diagnostic), Paludisme (parasitologie), Paludisme (traitement médicamenteux), Pays-Bas (MeSH), Réfugiés (MeSH), Splénomégalie (diagnostic), Splénomégalie (parasitologie), Splénomégalie (traitement médicamenteux), Syndrome (MeSH), Érythrée (MeSH).
MESH :
- diagnostic : Paludisme, Splénomégalie.
- parasitologie : Paludisme, Splénomégalie.
- traitement médicamenteux : Paludisme, Splénomégalie.
- Adulte, Humains, Hépatomégalie, Mâle, Pays-Bas, Réfugiés, Syndrome, Érythrée.

English descriptors

KwdEn :
- Adult (MeSH), Eritrea (MeSH), Hepatomegaly (MeSH), Humans (MeSH), Malaria (diagnosis), Malaria (drug therapy), Malaria (parasitology), Male (MeSH), Netherlands (MeSH), Refugees (MeSH), Splenomegaly (diagnosis), Splenomegaly (drug therapy), Splenomegaly (parasitology), Syndrome (MeSH).
MESH :
- diagnosis : Malaria, Splenomegaly.
- drug therapy : Malaria, Splenomegaly.
- parasitology : Malaria, Splenomegaly.
- Adult, Eritrea, Hepatomegaly, Humans, Male, Netherlands, Refugees, Syndrome.

Abstract

BACKGROUND

Hyper-reactive malaria splenomegaly (HMS) is a rare and potentially severe complication of malaria. It is likely that the incidence of patients with HMS will rise in the Netherlands due to the recent increase in asylum-seekers from Sub-Saharan Africa. It can be difficult to diagnose this disease, as this case shows.

CASE DESCRIPTION

A 31-year-old male from Eritrea was admitted with fever and dyspnea, caused by an influenza A-infection. The patient also presented with cachexia, pronounced hepatosplenomegaly and pancytopenia. Microscopic diagnostic analysis for malaria was negative. HMS was eventually diagnosed through high-sensitivity qPCR for malaria, which showed the presence of a very low level of Plasmodium falciparum parasitemia; furthermore, IgM levels were high and malaria serology was strongly positive.

CONCLUSION

HMS should be considered in patients from malaria-endemic areas presenting with splenomegaly and pancytopenia. Because standard diagnostics for malaria are often negative in this population, malaria serology and sensitive qPCR play an important diagnostic role.

PubMed: 27848905

Affiliations:

Links toward previous steps (curation, corpus...)

to stream Main, to step Corpus: 000060
to stream Main, to step Curation: 000060

Le document en format XML

<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">[Splenomegaly in an Eritrean refugee: the hyper-reactive malaria splenomegaly syndrome.]</title>
<author><name sortKey="Cruijsen, M M" sort="Cruijsen, M M" uniqKey="Cruijsen M" first="M M" last="Cruijsen">M M Cruijsen</name>
<affiliation wicri:level="3"><nlm:affiliation>Radboudumc, Nijmegen.</nlm:affiliation>
<country>Pays-Bas</country>
<placeName><settlement type="city">Nimègue</settlement>
<region type="province" nuts="2">Gueldre</region>
</placeName>
<wicri:orgArea>Radboudumc</wicri:orgArea>
</affiliation>
</author>
<author><name sortKey="Reuling, I J" sort="Reuling, I J" uniqKey="Reuling I" first="I J" last="Reuling">I J Reuling</name>
</author>
<author><name sortKey="Keuter, M" sort="Keuter, M" uniqKey="Keuter M" first="M" last="Keuter">M. Keuter</name>
</author>
<author><name sortKey="Sauerwein, R W" sort="Sauerwein, R W" uniqKey="Sauerwein R" first="R W" last="Sauerwein">R W Sauerwein</name>
</author>
<author><name sortKey="Van Der Ven, A J" sort="Van Der Ven, A J" uniqKey="Van Der Ven A" first="A J" last="Van Der Ven">A J Van Der Ven</name>
</author>
<author><name sortKey="De Mast, Q" sort="De Mast, Q" uniqKey="De Mast Q" first="Q" last="De Mast">Q. De Mast</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PubMed</idno>
<date when="2016">2016</date>
<idno type="RBID">pubmed:27848905</idno>
<idno type="pmid">27848905</idno>
<idno type="wicri:Area/Main/Corpus">000060</idno>
<idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Corpus" wicri:corpus="PubMed">000060</idno>
<idno type="wicri:Area/Main/Curation">000060</idno>
<idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Curation">000060</idno>
<idno type="wicri:Area/Main/Exploration">000060</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en">[Splenomegaly in an Eritrean refugee: the hyper-reactive malaria splenomegaly syndrome.]</title>
<author><name sortKey="Cruijsen, M M" sort="Cruijsen, M M" uniqKey="Cruijsen M" first="M M" last="Cruijsen">M M Cruijsen</name>
<affiliation wicri:level="3"><nlm:affiliation>Radboudumc, Nijmegen.</nlm:affiliation>
<country>Pays-Bas</country>
<placeName><settlement type="city">Nimègue</settlement>
<region type="province" nuts="2">Gueldre</region>
</placeName>
<wicri:orgArea>Radboudumc</wicri:orgArea>
</affiliation>
</author>
<author><name sortKey="Reuling, I J" sort="Reuling, I J" uniqKey="Reuling I" first="I J" last="Reuling">I J Reuling</name>
</author>
<author><name sortKey="Keuter, M" sort="Keuter, M" uniqKey="Keuter M" first="M" last="Keuter">M. Keuter</name>
</author>
<author><name sortKey="Sauerwein, R W" sort="Sauerwein, R W" uniqKey="Sauerwein R" first="R W" last="Sauerwein">R W Sauerwein</name>
</author>
<author><name sortKey="Van Der Ven, A J" sort="Van Der Ven, A J" uniqKey="Van Der Ven A" first="A J" last="Van Der Ven">A J Van Der Ven</name>
</author>
<author><name sortKey="De Mast, Q" sort="De Mast, Q" uniqKey="De Mast Q" first="Q" last="De Mast">Q. De Mast</name>
</author>
</analytic>
<series><title level="j">Nederlands tijdschrift voor geneeskunde</title>
<idno type="eISSN">1876-8784</idno>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult (MeSH)</term>
<term>Eritrea (MeSH)</term>
<term>Hepatomegaly (MeSH)</term>
<term>Humans (MeSH)</term>
<term>Malaria (diagnosis)</term>
<term>Malaria (drug therapy)</term>
<term>Malaria (parasitology)</term>
<term>Male (MeSH)</term>
<term>Netherlands (MeSH)</term>
<term>Refugees (MeSH)</term>
<term>Splenomegaly (diagnosis)</term>
<term>Splenomegaly (drug therapy)</term>
<term>Splenomegaly (parasitology)</term>
<term>Syndrome (MeSH)</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Adulte (MeSH)</term>
<term>Humains (MeSH)</term>
<term>Hépatomégalie (MeSH)</term>
<term>Mâle (MeSH)</term>
<term>Paludisme (diagnostic)</term>
<term>Paludisme (parasitologie)</term>
<term>Paludisme (traitement médicamenteux)</term>
<term>Pays-Bas (MeSH)</term>
<term>Réfugiés (MeSH)</term>
<term>Splénomégalie (diagnostic)</term>
<term>Splénomégalie (parasitologie)</term>
<term>Splénomégalie (traitement médicamenteux)</term>
<term>Syndrome (MeSH)</term>
<term>Érythrée (MeSH)</term>
</keywords>
<keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Malaria</term>
<term>Splenomegaly</term>
</keywords>
<keywords scheme="MESH" qualifier="diagnostic" xml:lang="fr"><term>Paludisme</term>
<term>Splénomégalie</term>
</keywords>
<keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Malaria</term>
<term>Splenomegaly</term>
</keywords>
<keywords scheme="MESH" qualifier="parasitologie" xml:lang="fr"><term>Paludisme</term>
<term>Splénomégalie</term>
</keywords>
<keywords scheme="MESH" qualifier="parasitology" xml:lang="en"><term>Malaria</term>
<term>Splenomegaly</term>
</keywords>
<keywords scheme="MESH" qualifier="traitement médicamenteux" xml:lang="fr"><term>Paludisme</term>
<term>Splénomégalie</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Adult</term>
<term>Eritrea</term>
<term>Hepatomegaly</term>
<term>Humans</term>
<term>Male</term>
<term>Netherlands</term>
<term>Refugees</term>
<term>Syndrome</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>Adulte</term>
<term>Humains</term>
<term>Hépatomégalie</term>
<term>Mâle</term>
<term>Pays-Bas</term>
<term>Réfugiés</term>
<term>Syndrome</term>
<term>Érythrée</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en"><p><b>BACKGROUND</b>
</p>
<p>Hyper-reactive malaria splenomegaly (HMS) is a rare and potentially severe complication of malaria. It is likely that the incidence of patients with HMS will rise in the Netherlands due to the recent increase in asylum-seekers from Sub-Saharan Africa. It can be difficult to diagnose this disease, as this case shows.</p>
</div>
<div type="abstract" xml:lang="en"><p><b>CASE DESCRIPTION</b>
</p>
<p>A 31-year-old male from Eritrea was admitted with fever and dyspnea, caused by an influenza A-infection. The patient also presented with cachexia, pronounced hepatosplenomegaly and pancytopenia. Microscopic diagnostic analysis for malaria was negative. HMS was eventually diagnosed through high-sensitivity qPCR for malaria, which showed the presence of a very low level of Plasmodium falciparum parasitemia; furthermore, IgM levels were high and malaria serology was strongly positive.</p>
</div>
<div type="abstract" xml:lang="en"><p><b>CONCLUSION</b>
</p>
<p>HMS should be considered in patients from malaria-endemic areas presenting with splenomegaly and pancytopenia. Because standard diagnostics for malaria are often negative in this population, malaria serology and sensitive qPCR play an important diagnostic role.</p>
</div>
</front>
</TEI>
<pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">27848905</PMID>
<DateCompleted><Year>2018</Year>
<Month>02</Month>
<Day>22</Day>
</DateCompleted>
<DateRevised><Year>2018</Year>
<Month>08</Month>
<Day>07</Day>
</DateRevised>
<Article PubModel="Print"><Journal><ISSN IssnType="Electronic">1876-8784</ISSN>
<JournalIssue CitedMedium="Internet"><Volume>160</Volume>
<PubDate><MedlineDate>2016</MedlineDate>
</PubDate>
</JournalIssue>
<Title>Nederlands tijdschrift voor geneeskunde</Title>
<ISOAbbreviation>Ned Tijdschr Geneeskd</ISOAbbreviation>
</Journal>
<ArticleTitle>[Splenomegaly in an Eritrean refugee: the hyper-reactive malaria splenomegaly syndrome.]</ArticleTitle>
<Pagination><MedlinePgn>D444</MedlinePgn>
</Pagination>
<Abstract><AbstractText Label="BACKGROUND">Hyper-reactive malaria splenomegaly (HMS) is a rare and potentially severe complication of malaria. It is likely that the incidence of patients with HMS will rise in the Netherlands due to the recent increase in asylum-seekers from Sub-Saharan Africa. It can be difficult to diagnose this disease, as this case shows.</AbstractText>
<AbstractText Label="CASE DESCRIPTION">A 31-year-old male from Eritrea was admitted with fever and dyspnea, caused by an influenza A-infection. The patient also presented with cachexia, pronounced hepatosplenomegaly and pancytopenia. Microscopic diagnostic analysis for malaria was negative. HMS was eventually diagnosed through high-sensitivity qPCR for malaria, which showed the presence of a very low level of Plasmodium falciparum parasitemia; furthermore, IgM levels were high and malaria serology was strongly positive.</AbstractText>
<AbstractText Label="CONCLUSION">HMS should be considered in patients from malaria-endemic areas presenting with splenomegaly and pancytopenia. Because standard diagnostics for malaria are often negative in this population, malaria serology and sensitive qPCR play an important diagnostic role.</AbstractText>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Cruijsen</LastName>
<ForeName>M M</ForeName>
<Initials>MM</Initials>
<AffiliationInfo><Affiliation>Radboudumc, Nijmegen.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Reuling</LastName>
<ForeName>I J</ForeName>
<Initials>IJ</Initials>
</Author>
<Author ValidYN="Y"><LastName>Keuter</LastName>
<ForeName>M</ForeName>
<Initials>M</Initials>
</Author>
<Author ValidYN="Y"><LastName>Sauerwein</LastName>
<ForeName>R W</ForeName>
<Initials>RW</Initials>
</Author>
<Author ValidYN="Y"><LastName>van der Ven</LastName>
<ForeName>A J</ForeName>
<Initials>AJ</Initials>
</Author>
<Author ValidYN="Y"><LastName>de Mast</LastName>
<ForeName>Q</ForeName>
<Initials>Q</Initials>
</Author>
</AuthorList>
<Language>dut</Language>
<PublicationTypeList><PublicationType UI="D002363">Case Reports</PublicationType>
<PublicationType UI="D016428">Journal Article</PublicationType>
</PublicationTypeList>
<VernacularTitle>Splenomegalie bij een Eritrese vluchteling.</VernacularTitle>
</Article>
<MedlineJournalInfo><Country>Netherlands</Country>
<MedlineTA>Ned Tijdschr Geneeskd</MedlineTA>
<NlmUniqueID>0400770</NlmUniqueID>
<ISSNLinking>0028-2162</ISSNLinking>
</MedlineJournalInfo>
<CitationSubset>IM</CitationSubset>
<MeshHeadingList><MeshHeading><DescriptorName UI="D000328" MajorTopicYN="N">Adult</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D019017" MajorTopicYN="N">Eritrea</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D006529" MajorTopicYN="N">Hepatomegaly</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008288" MajorTopicYN="N">Malaria</DescriptorName>
<QualifierName UI="Q000175" MajorTopicYN="Y">diagnosis</QualifierName>
<QualifierName UI="Q000188" MajorTopicYN="Y">drug therapy</QualifierName>
<QualifierName UI="Q000469" MajorTopicYN="N">parasitology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D009426" MajorTopicYN="N">Netherlands</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D012036" MajorTopicYN="Y">Refugees</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D013163" MajorTopicYN="N">Splenomegaly</DescriptorName>
<QualifierName UI="Q000175" MajorTopicYN="Y">diagnosis</QualifierName>
<QualifierName UI="Q000188" MajorTopicYN="Y">drug therapy</QualifierName>
<QualifierName UI="Q000469" MajorTopicYN="N">parasitology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D013577" MajorTopicYN="N">Syndrome</DescriptorName>
</MeshHeading>
</MeshHeadingList>
</MedlineCitation>
<PubmedData><History><PubMedPubDate PubStatus="entrez"><Year>2016</Year>
<Month>11</Month>
<Day>17</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="pubmed"><Year>2016</Year>
<Month>11</Month>
<Day>17</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="medline"><Year>2018</Year>
<Month>2</Month>
<Day>23</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
</History>
<PublicationStatus>ppublish</PublicationStatus>
<ArticleIdList><ArticleId IdType="pubmed">27848905</ArticleId>
</ArticleIdList>
</PubmedData>
</pubmed>
<affiliations><list><country><li>Pays-Bas</li>
</country>
<region><li>Gueldre</li>
</region>
<settlement><li>Nimègue</li>
</settlement>
</list>
<tree><noCountry><name sortKey="De Mast, Q" sort="De Mast, Q" uniqKey="De Mast Q" first="Q" last="De Mast">Q. De Mast</name>
<name sortKey="Keuter, M" sort="Keuter, M" uniqKey="Keuter M" first="M" last="Keuter">M. Keuter</name>
<name sortKey="Reuling, I J" sort="Reuling, I J" uniqKey="Reuling I" first="I J" last="Reuling">I J Reuling</name>
<name sortKey="Sauerwein, R W" sort="Sauerwein, R W" uniqKey="Sauerwein R" first="R W" last="Sauerwein">R W Sauerwein</name>
<name sortKey="Van Der Ven, A J" sort="Van Der Ven, A J" uniqKey="Van Der Ven A" first="A J" last="Van Der Ven">A J Van Der Ven</name>
</noCountry>
<country name="Pays-Bas"><region name="Gueldre"><name sortKey="Cruijsen, M M" sort="Cruijsen, M M" uniqKey="Cruijsen M" first="M M" last="Cruijsen">M M Cruijsen</name>
</region>
</country>
</tree>
</affiliations>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Sante/explor/GrippePaysBasV1/Data/Main/Exploration

HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000061 | SxmlIndent | more

HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000061 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Sante
   |area=    GrippePaysBasV1
   |flux=    Main
   |étape=   Exploration
   |type=    RBID
   |clé=     pubmed:27848905
   |texte=   [Splenomegaly in an Eritrean refugee: the hyper-reactive malaria splenomegaly syndrome.]
}}

Pour générer des pages wiki

HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i   -Sk "pubmed:27848905" \
       | HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd   \
       | NlmPubMed2Wicri -a GrippePaysBasV1

This area was generated with Dilib version V0.6.35.
Data generation: Mon Aug 10 10:18:30 2020. Site generation: Sat Mar 27 13:53:34 2021

	Serveur d'exploration sur la grippe aux Pays-Bas
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.

Serveur d'exploration sur la grippe aux Pays-Bas

[Splenomegaly in an Eritrean refugee: the hyper-reactive malaria splenomegaly syndrome.]

[Splenomegaly in an Eritrean refugee: the hyper-reactive malaria splenomegaly syndrome.]

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki