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Scenarios on costs and savings of influenza treatment and prevention for Dutch healthy working adults.

Identifieur interne : 000355 ( Main/Corpus ); précédent : 000354; suivant : 000356

Scenarios on costs and savings of influenza treatment and prevention for Dutch healthy working adults.

Auteurs : Maarten J. Postma ; Paul Jansema ; Huib W K F H. Scheijbeler ; Marianne L L. Van Genugten

Source :

RBID : pubmed:16029916

English descriptors

Abstract

OBJECTIVE

To assess the economic implications of strategies for influenza control among healthy working adults in The Netherlands.

METHODS

The economic evaluation was based on a pharmaco-economic model from the societal perspective. This model involves the direct and indirect costs of vaccination or treatment and the direct and indirect savings (averted costs) due to the control strategy. Control strategies comprised treatment with oseltamivir and prevention with the influenza vaccine. Clinical and economic parameter estimates were derived from published literature, databases and expert opinions. Several scenarios for age-groups and employment contracts (full-time versus not) were elaborated in combination with Monte Carlo simulation for probabilistic sensitivity analysis.

RESULTS

Consistently, net cost savings are estimated over the range of age groups and scenarios considered. Net savings are smallest for half-time workers. Incremental analysis indicates that on average prevention renders higher cost savings than treatment.

CONCLUSION

We found a consistent picture of net cost savings for prevention through vaccination and treatment with oseltamivir of influenza in healthy working adults in The Netherlands.


DOI: 10.1016/j.vaccine.2005.06.007
PubMed: 16029916

Links to Exploration step

pubmed:16029916

Le document en format XML

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<name sortKey="Postma, Maarten J" sort="Postma, Maarten J" uniqKey="Postma M" first="Maarten J" last="Postma">Maarten J. Postma</name>
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<name sortKey="Jansema, Paul" sort="Jansema, Paul" uniqKey="Jansema P" first="Paul" last="Jansema">Paul Jansema</name>
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<name sortKey="Scheijbeler, Huib W K F H" sort="Scheijbeler, Huib W K F H" uniqKey="Scheijbeler H" first="Huib W K F H" last="Scheijbeler">Huib W K F H. Scheijbeler</name>
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<name sortKey="Van Genugten, Marianne L L" sort="Van Genugten, Marianne L L" uniqKey="Van Genugten M" first="Marianne L L" last="Van Genugten">Marianne L L. Van Genugten</name>
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<term>Absenteeism (MeSH)</term>
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<term>Adult (MeSH)</term>
<term>Age Factors (MeSH)</term>
<term>Aged (MeSH)</term>
<term>Cohort Studies (MeSH)</term>
<term>Cost Savings (MeSH)</term>
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<term>Efficiency (MeSH)</term>
<term>Employment (economics)</term>
<term>Female (MeSH)</term>
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<term>Absenteeism</term>
<term>Adolescent</term>
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<term>Age Factors</term>
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<term>Cohort Studies</term>
<term>Cost Savings</term>
<term>Costs and Cost Analysis</term>
<term>Efficiency</term>
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<b>OBJECTIVE</b>
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<p>To assess the economic implications of strategies for influenza control among healthy working adults in The Netherlands.</p>
</div>
<div type="abstract" xml:lang="en">
<p>
<b>METHODS</b>
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<p>The economic evaluation was based on a pharmaco-economic model from the societal perspective. This model involves the direct and indirect costs of vaccination or treatment and the direct and indirect savings (averted costs) due to the control strategy. Control strategies comprised treatment with oseltamivir and prevention with the influenza vaccine. Clinical and economic parameter estimates were derived from published literature, databases and expert opinions. Several scenarios for age-groups and employment contracts (full-time versus not) were elaborated in combination with Monte Carlo simulation for probabilistic sensitivity analysis.</p>
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<p>
<b>RESULTS</b>
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<p>Consistently, net cost savings are estimated over the range of age groups and scenarios considered. Net savings are smallest for half-time workers. Incremental analysis indicates that on average prevention renders higher cost savings than treatment.</p>
</div>
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<p>
<b>CONCLUSION</b>
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<p>We found a consistent picture of net cost savings for prevention through vaccination and treatment with oseltamivir of influenza in healthy working adults in The Netherlands.</p>
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