GrippeEspagneV1, Main, Exploration, bibRecord, 000030

Influenza vaccine effectiveness against laboratory-confirmed influenza in hospitalised adults aged 60 years or older, Valencia Region, Spain, 2017/18 influenza season.

Identifieur interne : 000030 ( Main/Exploration ); précédent : 000029; suivant : 000031

Influenza vaccine effectiveness against laboratory-confirmed influenza in hospitalised adults aged 60 years or older, Valencia Region, Spain, 2017/18 influenza season.

Auteurs : Ainara Mira-Iglesias [Espagne] ; F Xavier L Pez-Labrador [Espagne] ; Víctor Baselga-Moreno [Espagne] ; Miguel Tortajada-Girbés [Espagne] ; Juan Mollar-Maseres [Espagne] ; Mario Carballido-Fernández [Espagne] ; Germán Schwarz-Chavarri [Espagne] ; Joan Puig-Barberà [Espagne] ; Javier Díez-Domingo [Espagne] ; On Behalf Of The Valencia Hospital Network For The Study Of Influenza And Respiratory Viruses Disease

Source :

Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin [ 1560-7917 ] ; 2019.

RBID : pubmed:31387672

Descripteurs français

KwdFr :
- Adulte d'âge moyen (MeSH), Espagne (épidémiologie), Femelle (MeSH), Grippe humaine (immunologie), Grippe humaine (virologie), Grippe humaine (épidémiologie), Hospitalisation (statistiques et données numériques), Humains (MeSH), Mâle (MeSH), Résultat thérapeutique (MeSH), Saisons (MeSH), Sous-type H1N1 du virus de la grippe A (immunologie), Sous-type H1N1 du virus de la grippe A (isolement et purification), Sous-type H3N2 du virus de la grippe A (immunologie), Sous-type H3N2 du virus de la grippe A (isolement et purification), Sujet âgé (MeSH), Surveillance sentinelle (MeSH), Vaccination (statistiques et données numériques), Vaccins antigrippaux (immunologie), Vaccins antigrippaux (usage thérapeutique), Virus influenza B (immunologie), Virus influenza B (isolement et purification).
MESH :
- immunologie : Grippe humaine, Sous-type H1N1 du virus de la grippe A, Sous-type H3N2 du virus de la grippe A, Vaccins antigrippaux, Virus influenza B.
- isolement et purification : Sous-type H1N1 du virus de la grippe A, Sous-type H3N2 du virus de la grippe A, Virus influenza B.
- statistiques et données numériques : Hospitalisation, Vaccination.
- usage thérapeutique : Vaccins antigrippaux.
- virologie : Grippe humaine.
- épidémiologie : Espagne, Grippe humaine.
- Adulte d'âge moyen, Femelle, Humains, Mâle, Résultat thérapeutique, Saisons, Sujet âgé, Surveillance sentinelle.
Wicri :
- geographic : Espagne.

English descriptors

KwdEn :
- Aged (MeSH), Female (MeSH), Hospitalization (statistics & numerical data), Humans (MeSH), Influenza A Virus, H1N1 Subtype (immunology), Influenza A Virus, H1N1 Subtype (isolation & purification), Influenza A Virus, H3N2 Subtype (immunology), Influenza A Virus, H3N2 Subtype (isolation & purification), Influenza B virus (immunology), Influenza B virus (isolation & purification), Influenza Vaccines (immunology), Influenza Vaccines (therapeutic use), Influenza, Human (epidemiology), Influenza, Human (immunology), Influenza, Human (virology), Male (MeSH), Middle Aged (MeSH), Seasons (MeSH), Sentinel Surveillance (MeSH), Spain (epidemiology), Treatment Outcome (MeSH), Vaccination (statistics & numerical data).
MESH :
- chemical , immunology : Influenza Vaccines.
- geographic , epidemiology : Spain.
- epidemiology : Influenza, Human.
- immunology : Influenza A Virus, H1N1 Subtype, Influenza A Virus, H3N2 Subtype, Influenza B virus, Influenza, Human.
- isolation & purification : Influenza A Virus, H1N1 Subtype, Influenza A Virus, H3N2 Subtype, Influenza B virus.
- statistics & numerical data : Hospitalization, Vaccination.
- chemical , therapeutic use : Influenza Vaccines.
- virology : Influenza, Human.
- Aged, Female, Humans, Male, Middle Aged, Seasons, Sentinel Surveillance, Treatment Outcome.

Abstract

IntroductionInfluenza immunisation is recommended for elderly people each season. The influenza vaccine effectiveness (IVE) varies annually due to influenza viruses evolving and the vaccine composition.AimTo estimate, in inpatients ≥ 60 years old, the 2017/18 trivalent IVE, overall, by vaccine type and by strain. The impact of vaccination in any of the two previous seasons (2016/17 and 2015/16) on current (2017/18) IVE was also explored.MethodsThis was a multicentre prospective observational study within the Valencia Hospital Surveillance Network for the Study of Influenza and Respiratory Viruses Disease (VAHNSI, Spain). The test-negative design was applied taking laboratory-confirmed influenza as outcome and vaccination status as main exposure. Information about potential confounders was obtained from clinical registries and/or by interviewing patients; vaccine information was only ascertained by registries.ResultsOverall, 2017/18 IVE was 9.9% (95% CI: -15.5 to 29.6%), and specifically, 48.3% (95% CI: 13.5% to 69.1%), -29.9% (95% CI: -79.1% to 5.8%) and 25.7% (95% CI: -8.8% to 49.3%) against A(H1N1)pdm09, A(H3N2) and B/Yamagata lineage, respectively. For the adjuvanted and non-adjuvanted vaccines, overall IVE was 10.0% (95% CI: -24.4% to 34.9%) and 7.8% (95% CI: -23.1% to 31.0%) respectively. Prior vaccination significantly protected against influenza B/Yamagata lineage (IVE: 50.2%; 95% CI: 2.3% to 74.6%) in patients not vaccinated in the current season. For those repeatedly vaccinated against influenza A(H1N1)pdm09, IVE was 46.4% (95% CI: 6.8% to 69.2%).ConclusionOur data revealed low vaccine effectiveness against influenza in hospitalised patients ≥60 years old in 2017/18. Prior vaccination protected against influenza A(H1N1)pdm09 and B/Yamagata-lineage.

DOI: 10.2807/1560-7917.ES.2019.24.31.1800461
PubMed: 31387672
PubMed Central: PMC6685101

Affiliations:

Links toward previous steps (curation, corpus...)

to stream Main, to step Corpus: 00011
to stream Main, to step Curation: 000011

Le document en format XML

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<author><name sortKey="Mira Iglesias, Ainara" sort="Mira Iglesias, Ainara" uniqKey="Mira Iglesias A" first="Ainara" last="Mira-Iglesias">Ainara Mira-Iglesias</name>
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<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO-Public Health), Valencia</wicri:regionArea>
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<author><name sortKey="L Pez Labrador, F Xavier" sort="L Pez Labrador, F Xavier" uniqKey="L Pez Labrador F" first="F Xavier" last="L Pez-Labrador">F Xavier L Pez-Labrador</name>
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<author><name sortKey="Baselga Moreno, Victor" sort="Baselga Moreno, Victor" uniqKey="Baselga Moreno V" first="Víctor" last="Baselga-Moreno">Víctor Baselga-Moreno</name>
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<author><name sortKey="Carballido Fernandez, Mario" sort="Carballido Fernandez, Mario" uniqKey="Carballido Fernandez M" first="Mario" last="Carballido-Fernández">Mario Carballido-Fernández</name>
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<author><name sortKey="Schwarz Chavarri, German" sort="Schwarz Chavarri, German" uniqKey="Schwarz Chavarri G" first="Germán" last="Schwarz-Chavarri">Germán Schwarz-Chavarri</name>
<affiliation wicri:level="1"><nlm:affiliation>Hospital General de Alicante, Alicante, Spain.</nlm:affiliation>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Hospital General de Alicante, Alicante</wicri:regionArea>
<wicri:noRegion>Alicante</wicri:noRegion>
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<author><name sortKey="Puig Barbera, Joan" sort="Puig Barbera, Joan" uniqKey="Puig Barbera J" first="Joan" last="Puig-Barberà">Joan Puig-Barberà</name>
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<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Centro de Salud Pública de Castellón, Castellón</wicri:regionArea>
<wicri:noRegion>Castellón</wicri:noRegion>
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<affiliation wicri:level="1"><nlm:affiliation>Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO-Public Health), Valencia, Spain.</nlm:affiliation>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO-Public Health), Valencia</wicri:regionArea>
<wicri:noRegion>Valencia</wicri:noRegion>
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<author><name sortKey="Diez Domingo, Javier" sort="Diez Domingo, Javier" uniqKey="Diez Domingo J" first="Javier" last="Díez-Domingo">Javier Díez-Domingo</name>
<affiliation wicri:level="1"><nlm:affiliation>Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO-Public Health), Valencia, Spain.</nlm:affiliation>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO-Public Health), Valencia</wicri:regionArea>
<wicri:noRegion>Valencia</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="On Behalf Of The Valencia Hospital Network For The Study Of Influenza And Respiratory Viruses Disease" sort="On Behalf Of The Valencia Hospital Network For The Study Of Influenza And Respiratory Viruses Disease" uniqKey="On Behalf Of The Valencia Hospital Network For The Study Of Influenza And Respiratory Viruses Disease" last="On Behalf Of The Valencia Hospital Network For The Study Of Influenza And Respiratory Viruses Disease">On Behalf Of The Valencia Hospital Network For The Study Of Influenza And Respiratory Viruses Disease</name>
<affiliation><nlm:affiliation>The Network members are acknowledged at the end of the article.</nlm:affiliation>
<wicri:noCountry code="no comma">The Network members are acknowledged at the end of the article.</wicri:noCountry>
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<sourceDesc><biblStruct><analytic><title xml:lang="en">Influenza vaccine effectiveness against laboratory-confirmed influenza in hospitalised adults aged 60 years or older, Valencia Region, Spain, 2017/18 influenza season.</title>
<author><name sortKey="Mira Iglesias, Ainara" sort="Mira Iglesias, Ainara" uniqKey="Mira Iglesias A" first="Ainara" last="Mira-Iglesias">Ainara Mira-Iglesias</name>
<affiliation wicri:level="1"><nlm:affiliation>Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO-Public Health), Valencia, Spain.</nlm:affiliation>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO-Public Health), Valencia</wicri:regionArea>
<wicri:noRegion>Valencia</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="L Pez Labrador, F Xavier" sort="L Pez Labrador, F Xavier" uniqKey="L Pez Labrador F" first="F Xavier" last="L Pez-Labrador">F Xavier L Pez-Labrador</name>
<affiliation wicri:level="3"><nlm:affiliation>Consorcio de Investigación Biomédica de Epidemiología y Salud Pública (CIBERESP), Instituto de Salud Carlos III, Madrid, Spain.</nlm:affiliation>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Consorcio de Investigación Biomédica de Epidemiología y Salud Pública (CIBERESP), Instituto de Salud Carlos III, Madrid</wicri:regionArea>
<placeName><settlement type="city">Madrid</settlement>
<region nuts="2" type="region">Communauté de Madrid</region>
</placeName>
</affiliation>
<affiliation wicri:level="1"><nlm:affiliation>Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO-Public Health), Valencia, Spain.</nlm:affiliation>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO-Public Health), Valencia</wicri:regionArea>
<wicri:noRegion>Valencia</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Baselga Moreno, Victor" sort="Baselga Moreno, Victor" uniqKey="Baselga Moreno V" first="Víctor" last="Baselga-Moreno">Víctor Baselga-Moreno</name>
<affiliation wicri:level="1"><nlm:affiliation>Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO-Public Health), Valencia, Spain.</nlm:affiliation>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO-Public Health), Valencia</wicri:regionArea>
<wicri:noRegion>Valencia</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Tortajada Girbes, Miguel" sort="Tortajada Girbes, Miguel" uniqKey="Tortajada Girbes M" first="Miguel" last="Tortajada-Girbés">Miguel Tortajada-Girbés</name>
<affiliation wicri:level="1"><nlm:affiliation>Hospital Doctor Peset, Valencia, Spain.</nlm:affiliation>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Hospital Doctor Peset, Valencia</wicri:regionArea>
<wicri:noRegion>Valencia</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Mollar Maseres, Juan" sort="Mollar Maseres, Juan" uniqKey="Mollar Maseres J" first="Juan" last="Mollar-Maseres">Juan Mollar-Maseres</name>
<affiliation wicri:level="1"><nlm:affiliation>Hospital Universitario y Politécnico La Fe, Valencia, Spain.</nlm:affiliation>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Hospital Universitario y Politécnico La Fe, Valencia</wicri:regionArea>
<wicri:noRegion>Valencia</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Carballido Fernandez, Mario" sort="Carballido Fernandez, Mario" uniqKey="Carballido Fernandez M" first="Mario" last="Carballido-Fernández">Mario Carballido-Fernández</name>
<affiliation wicri:level="1"><nlm:affiliation>Universidad CEU Cardenal Herrera, Castellón, Spain.</nlm:affiliation>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Universidad CEU Cardenal Herrera, Castellón</wicri:regionArea>
<wicri:noRegion>Castellón</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1"><nlm:affiliation>Hospital General Universitario de Castellón, Castellón, Spain.</nlm:affiliation>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Hospital General Universitario de Castellón, Castellón</wicri:regionArea>
<wicri:noRegion>Castellón</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Schwarz Chavarri, German" sort="Schwarz Chavarri, German" uniqKey="Schwarz Chavarri G" first="Germán" last="Schwarz-Chavarri">Germán Schwarz-Chavarri</name>
<affiliation wicri:level="1"><nlm:affiliation>Hospital General de Alicante, Alicante, Spain.</nlm:affiliation>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Hospital General de Alicante, Alicante</wicri:regionArea>
<wicri:noRegion>Alicante</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Puig Barbera, Joan" sort="Puig Barbera, Joan" uniqKey="Puig Barbera J" first="Joan" last="Puig-Barberà">Joan Puig-Barberà</name>
<affiliation wicri:level="1"><nlm:affiliation>Centro de Salud Pública de Castellón, Castellón, Spain.</nlm:affiliation>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Centro de Salud Pública de Castellón, Castellón</wicri:regionArea>
<wicri:noRegion>Castellón</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1"><nlm:affiliation>Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO-Public Health), Valencia, Spain.</nlm:affiliation>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO-Public Health), Valencia</wicri:regionArea>
<wicri:noRegion>Valencia</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Diez Domingo, Javier" sort="Diez Domingo, Javier" uniqKey="Diez Domingo J" first="Javier" last="Díez-Domingo">Javier Díez-Domingo</name>
<affiliation wicri:level="1"><nlm:affiliation>Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO-Public Health), Valencia, Spain.</nlm:affiliation>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO-Public Health), Valencia</wicri:regionArea>
<wicri:noRegion>Valencia</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="On Behalf Of The Valencia Hospital Network For The Study Of Influenza And Respiratory Viruses Disease" sort="On Behalf Of The Valencia Hospital Network For The Study Of Influenza And Respiratory Viruses Disease" uniqKey="On Behalf Of The Valencia Hospital Network For The Study Of Influenza And Respiratory Viruses Disease" last="On Behalf Of The Valencia Hospital Network For The Study Of Influenza And Respiratory Viruses Disease">On Behalf Of The Valencia Hospital Network For The Study Of Influenza And Respiratory Viruses Disease</name>
<affiliation><nlm:affiliation>The Network members are acknowledged at the end of the article.</nlm:affiliation>
<wicri:noCountry code="no comma">The Network members are acknowledged at the end of the article.</wicri:noCountry>
</affiliation>
</author>
</analytic>
<series><title level="j">Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin</title>
<idno type="eISSN">1560-7917</idno>
<imprint><date when="2019" type="published">2019</date>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Aged (MeSH)</term>
<term>Female (MeSH)</term>
<term>Hospitalization (statistics & numerical data)</term>
<term>Humans (MeSH)</term>
<term>Influenza A Virus, H1N1 Subtype (immunology)</term>
<term>Influenza A Virus, H1N1 Subtype (isolation & purification)</term>
<term>Influenza A Virus, H3N2 Subtype (immunology)</term>
<term>Influenza A Virus, H3N2 Subtype (isolation & purification)</term>
<term>Influenza B virus (immunology)</term>
<term>Influenza B virus (isolation & purification)</term>
<term>Influenza Vaccines (immunology)</term>
<term>Influenza Vaccines (therapeutic use)</term>
<term>Influenza, Human (epidemiology)</term>
<term>Influenza, Human (immunology)</term>
<term>Influenza, Human (virology)</term>
<term>Male (MeSH)</term>
<term>Middle Aged (MeSH)</term>
<term>Seasons (MeSH)</term>
<term>Sentinel Surveillance (MeSH)</term>
<term>Spain (epidemiology)</term>
<term>Treatment Outcome (MeSH)</term>
<term>Vaccination (statistics & numerical data)</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Adulte d'âge moyen (MeSH)</term>
<term>Espagne (épidémiologie)</term>
<term>Femelle (MeSH)</term>
<term>Grippe humaine (immunologie)</term>
<term>Grippe humaine (virologie)</term>
<term>Grippe humaine (épidémiologie)</term>
<term>Hospitalisation (statistiques et données numériques)</term>
<term>Humains (MeSH)</term>
<term>Mâle (MeSH)</term>
<term>Résultat thérapeutique (MeSH)</term>
<term>Saisons (MeSH)</term>
<term>Sous-type H1N1 du virus de la grippe A (immunologie)</term>
<term>Sous-type H1N1 du virus de la grippe A (isolement et purification)</term>
<term>Sous-type H3N2 du virus de la grippe A (immunologie)</term>
<term>Sous-type H3N2 du virus de la grippe A (isolement et purification)</term>
<term>Sujet âgé (MeSH)</term>
<term>Surveillance sentinelle (MeSH)</term>
<term>Vaccination (statistiques et données numériques)</term>
<term>Vaccins antigrippaux (immunologie)</term>
<term>Vaccins antigrippaux (usage thérapeutique)</term>
<term>Virus influenza B (immunologie)</term>
<term>Virus influenza B (isolement et purification)</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="immunology" xml:lang="en"><term>Influenza Vaccines</term>
</keywords>
<keywords scheme="MESH" type="geographic" qualifier="epidemiology" xml:lang="en"><term>Spain</term>
</keywords>
<keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Influenza, Human</term>
</keywords>
<keywords scheme="MESH" qualifier="immunologie" xml:lang="fr"><term>Grippe humaine</term>
<term>Sous-type H1N1 du virus de la grippe A</term>
<term>Sous-type H3N2 du virus de la grippe A</term>
<term>Vaccins antigrippaux</term>
<term>Virus influenza B</term>
</keywords>
<keywords scheme="MESH" qualifier="immunology" xml:lang="en"><term>Influenza A Virus, H1N1 Subtype</term>
<term>Influenza A Virus, H3N2 Subtype</term>
<term>Influenza B virus</term>
<term>Influenza, Human</term>
</keywords>
<keywords scheme="MESH" qualifier="isolation & purification" xml:lang="en"><term>Influenza A Virus, H1N1 Subtype</term>
<term>Influenza A Virus, H3N2 Subtype</term>
<term>Influenza B virus</term>
</keywords>
<keywords scheme="MESH" qualifier="isolement et purification" xml:lang="fr"><term>Sous-type H1N1 du virus de la grippe A</term>
<term>Sous-type H3N2 du virus de la grippe A</term>
<term>Virus influenza B</term>
</keywords>
<keywords scheme="MESH" qualifier="statistics & numerical data" xml:lang="en"><term>Hospitalization</term>
<term>Vaccination</term>
</keywords>
<keywords scheme="MESH" qualifier="statistiques et données numériques" xml:lang="fr"><term>Hospitalisation</term>
<term>Vaccination</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Influenza Vaccines</term>
</keywords>
<keywords scheme="MESH" qualifier="usage thérapeutique" xml:lang="fr"><term>Vaccins antigrippaux</term>
</keywords>
<keywords scheme="MESH" qualifier="virologie" xml:lang="fr"><term>Grippe humaine</term>
</keywords>
<keywords scheme="MESH" qualifier="virology" xml:lang="en"><term>Influenza, Human</term>
</keywords>
<keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr"><term>Espagne</term>
<term>Grippe humaine</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Aged</term>
<term>Female</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Seasons</term>
<term>Sentinel Surveillance</term>
<term>Treatment Outcome</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>Adulte d'âge moyen</term>
<term>Femelle</term>
<term>Humains</term>
<term>Mâle</term>
<term>Résultat thérapeutique</term>
<term>Saisons</term>
<term>Sujet âgé</term>
<term>Surveillance sentinelle</term>
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<front><div type="abstract" xml:lang="en">IntroductionInfluenza immunisation is recommended for elderly people each season. The influenza vaccine effectiveness (IVE) varies annually due to influenza viruses evolving and the vaccine composition.AimTo estimate, in inpatients ≥ 60 years old, the 2017/18 trivalent IVE, overall, by vaccine type and by strain. The impact of vaccination in any of the two previous seasons (2016/17 and 2015/16) on current (2017/18) IVE was also explored.MethodsThis was a multicentre prospective observational study within the Valencia Hospital Surveillance Network for the Study of Influenza and Respiratory Viruses Disease (VAHNSI, Spain). The test-negative design was applied taking laboratory-confirmed influenza as outcome and vaccination status as main exposure. Information about potential confounders was obtained from clinical registries and/or by interviewing patients; vaccine information was only ascertained by registries.ResultsOverall, 2017/18 IVE was 9.9% (95% CI: -15.5 to 29.6%), and specifically, 48.3% (95% CI: 13.5% to 69.1%), -29.9% (95% CI: -79.1% to 5.8%) and 25.7% (95% CI: -8.8% to 49.3%) against A(H1N1)pdm09, A(H3N2) and B/Yamagata lineage, respectively. For the adjuvanted and non-adjuvanted vaccines, overall IVE was 10.0% (95% CI: -24.4% to 34.9%) and 7.8% (95% CI: -23.1% to 31.0%) respectively. Prior vaccination significantly protected against influenza B/Yamagata lineage (IVE: 50.2%; 95% CI: 2.3% to 74.6%) in patients not vaccinated in the current season. For those repeatedly vaccinated against influenza A(H1N1)pdm09, IVE was 46.4% (95% CI: 6.8% to 69.2%).ConclusionOur data revealed low vaccine effectiveness against influenza in hospitalised patients ≥60 years old in 2017/18. Prior vaccination protected against influenza A(H1N1)pdm09 and B/Yamagata-lineage.</div>
</front>
</TEI>
<pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">31387672</PMID>
<DateCompleted><Year>2020</Year>
<Month>07</Month>
<Day>17</Day>
</DateCompleted>
<DateRevised><Year>2020</Year>
<Month>07</Month>
<Day>17</Day>
</DateRevised>
<Article PubModel="Print"><Journal><ISSN IssnType="Electronic">1560-7917</ISSN>
<JournalIssue CitedMedium="Internet"><Volume>24</Volume>
<Issue>31</Issue>
<PubDate><Year>2019</Year>
<Month>Aug</Month>
</PubDate>
</JournalIssue>
<Title>Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin</Title>
<ISOAbbreviation>Euro Surveill.</ISOAbbreviation>
</Journal>
<ArticleTitle>Influenza vaccine effectiveness against laboratory-confirmed influenza in hospitalised adults aged 60 years or older, Valencia Region, Spain, 2017/18 influenza season.</ArticleTitle>
<ELocationID EIdType="doi" ValidYN="Y">10.2807/1560-7917.ES.2019.24.31.1800461</ELocationID>
<Abstract><AbstractText>IntroductionInfluenza immunisation is recommended for elderly people each season. The influenza vaccine effectiveness (IVE) varies annually due to influenza viruses evolving and the vaccine composition.AimTo estimate, in inpatients ≥ 60 years old, the 2017/18 trivalent IVE, overall, by vaccine type and by strain. The impact of vaccination in any of the two previous seasons (2016/17 and 2015/16) on current (2017/18) IVE was also explored.MethodsThis was a multicentre prospective observational study within the Valencia Hospital Surveillance Network for the Study of Influenza and Respiratory Viruses Disease (VAHNSI, Spain). The test-negative design was applied taking laboratory-confirmed influenza as outcome and vaccination status as main exposure. Information about potential confounders was obtained from clinical registries and/or by interviewing patients; vaccine information was only ascertained by registries.ResultsOverall, 2017/18 IVE was 9.9% (95% CI: -15.5 to 29.6%), and specifically, 48.3% (95% CI: 13.5% to 69.1%), -29.9% (95% CI: -79.1% to 5.8%) and 25.7% (95% CI: -8.8% to 49.3%) against A(H1N1)pdm09, A(H3N2) and B/Yamagata lineage, respectively. For the adjuvanted and non-adjuvanted vaccines, overall IVE was 10.0% (95% CI: -24.4% to 34.9%) and 7.8% (95% CI: -23.1% to 31.0%) respectively. Prior vaccination significantly protected against influenza B/Yamagata lineage (IVE: 50.2%; 95% CI: 2.3% to 74.6%) in patients not vaccinated in the current season. For those repeatedly vaccinated against influenza A(H1N1)pdm09, IVE was 46.4% (95% CI: 6.8% to 69.2%).ConclusionOur data revealed low vaccine effectiveness against influenza in hospitalised patients ≥60 years old in 2017/18. Prior vaccination protected against influenza A(H1N1)pdm09 and B/Yamagata-lineage.</AbstractText>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Mira-Iglesias</LastName>
<ForeName>Ainara</ForeName>
<Initials>A</Initials>
<AffiliationInfo><Affiliation>Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO-Public Health), Valencia, Spain.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>López-Labrador</LastName>
<ForeName>F Xavier</ForeName>
<Initials>FX</Initials>
<AffiliationInfo><Affiliation>Consorcio de Investigación Biomédica de Epidemiología y Salud Pública (CIBERESP), Instituto de Salud Carlos III, Madrid, Spain.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO-Public Health), Valencia, Spain.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Baselga-Moreno</LastName>
<ForeName>Víctor</ForeName>
<Initials>V</Initials>
<AffiliationInfo><Affiliation>Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO-Public Health), Valencia, Spain.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Tortajada-Girbés</LastName>
<ForeName>Miguel</ForeName>
<Initials>M</Initials>
<AffiliationInfo><Affiliation>Hospital Doctor Peset, Valencia, Spain.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Mollar-Maseres</LastName>
<ForeName>Juan</ForeName>
<Initials>J</Initials>
<AffiliationInfo><Affiliation>Hospital Universitario y Politécnico La Fe, Valencia, Spain.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Carballido-Fernández</LastName>
<ForeName>Mario</ForeName>
<Initials>M</Initials>
<AffiliationInfo><Affiliation>Universidad CEU Cardenal Herrera, Castellón, Spain.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Hospital General Universitario de Castellón, Castellón, Spain.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Schwarz-Chavarri</LastName>
<ForeName>Germán</ForeName>
<Initials>G</Initials>
<AffiliationInfo><Affiliation>Hospital General de Alicante, Alicante, Spain.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Puig-Barberà</LastName>
<ForeName>Joan</ForeName>
<Initials>J</Initials>
<AffiliationInfo><Affiliation>Centro de Salud Pública de Castellón, Castellón, Spain.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO-Public Health), Valencia, Spain.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Díez-Domingo</LastName>
<ForeName>Javier</ForeName>
<Initials>J</Initials>
<AffiliationInfo><Affiliation>Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO-Public Health), Valencia, Spain.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>On Behalf Of The Valencia Hospital Network For The Study Of Influenza And Respiratory Viruses Disease</LastName>
<AffiliationInfo><Affiliation>The Network members are acknowledged at the end of the article.</Affiliation>
</AffiliationInfo>
</Author>
</AuthorList>
<Language>eng</Language>
<PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType>
<PublicationType UI="D064888">Observational Study</PublicationType>
</PublicationTypeList>
</Article>
<MedlineJournalInfo><Country>Sweden</Country>
<MedlineTA>Euro Surveill</MedlineTA>
<NlmUniqueID>100887452</NlmUniqueID>
<ISSNLinking>1025-496X</ISSNLinking>
</MedlineJournalInfo>
<ChemicalList><Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="D007252">Influenza Vaccines</NameOfSubstance>
</Chemical>
</ChemicalList>
<CitationSubset>IM</CitationSubset>
<MeshHeadingList><MeshHeading><DescriptorName UI="D000368" MajorTopicYN="N">Aged</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D006760" MajorTopicYN="N">Hospitalization</DescriptorName>
<QualifierName UI="Q000706" MajorTopicYN="Y">statistics & numerical data</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D053118" MajorTopicYN="N">Influenza A Virus, H1N1 Subtype</DescriptorName>
<QualifierName UI="Q000276" MajorTopicYN="Y">immunology</QualifierName>
<QualifierName UI="Q000302" MajorTopicYN="N">isolation & purification</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D053122" MajorTopicYN="N">Influenza A Virus, H3N2 Subtype</DescriptorName>
<QualifierName UI="Q000276" MajorTopicYN="Y">immunology</QualifierName>
<QualifierName UI="Q000302" MajorTopicYN="N">isolation & purification</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D009981" MajorTopicYN="N">Influenza B virus</DescriptorName>
<QualifierName UI="Q000276" MajorTopicYN="Y">immunology</QualifierName>
<QualifierName UI="Q000302" MajorTopicYN="N">isolation & purification</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D007252" MajorTopicYN="N">Influenza Vaccines</DescriptorName>
<QualifierName UI="Q000276" MajorTopicYN="Y">immunology</QualifierName>
<QualifierName UI="Q000627" MajorTopicYN="Y">therapeutic use</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D007251" MajorTopicYN="N">Influenza, Human</DescriptorName>
<QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName>
<QualifierName UI="Q000276" MajorTopicYN="Y">immunology</QualifierName>
<QualifierName UI="Q000821" MajorTopicYN="N">virology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D012621" MajorTopicYN="N">Seasons</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D018571" MajorTopicYN="N">Sentinel Surveillance</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D013030" MajorTopicYN="N" Type="Geographic">Spain</DescriptorName>
<QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D016896" MajorTopicYN="N">Treatment Outcome</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D014611" MajorTopicYN="N">Vaccination</DescriptorName>
<QualifierName UI="Q000706" MajorTopicYN="N">statistics & numerical data</QualifierName>
</MeshHeading>
</MeshHeadingList>
<KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">Spain</Keyword>
<Keyword MajorTopicYN="N">epidemiology</Keyword>
<Keyword MajorTopicYN="N">hospitalisations</Keyword>
<Keyword MajorTopicYN="N">influenza</Keyword>
<Keyword MajorTopicYN="N">influenza virus</Keyword>
<Keyword MajorTopicYN="N">surveillance</Keyword>
<Keyword MajorTopicYN="N">vaccine</Keyword>
<Keyword MajorTopicYN="N">viral infections</Keyword>
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</country>
<region><li>Communauté de Madrid</li>
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<settlement><li>Madrid</li>
</settlement>
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<name sortKey="Baselga Moreno, Victor" sort="Baselga Moreno, Victor" uniqKey="Baselga Moreno V" first="Víctor" last="Baselga-Moreno">Víctor Baselga-Moreno</name>
<name sortKey="Carballido Fernandez, Mario" sort="Carballido Fernandez, Mario" uniqKey="Carballido Fernandez M" first="Mario" last="Carballido-Fernández">Mario Carballido-Fernández</name>
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<name sortKey="Puig Barbera, Joan" sort="Puig Barbera, Joan" uniqKey="Puig Barbera J" first="Joan" last="Puig-Barberà">Joan Puig-Barberà</name>
<name sortKey="Puig Barbera, Joan" sort="Puig Barbera, Joan" uniqKey="Puig Barbera J" first="Joan" last="Puig-Barberà">Joan Puig-Barberà</name>
<name sortKey="Schwarz Chavarri, German" sort="Schwarz Chavarri, German" uniqKey="Schwarz Chavarri G" first="Germán" last="Schwarz-Chavarri">Germán Schwarz-Chavarri</name>
<name sortKey="Tortajada Girbes, Miguel" sort="Tortajada Girbes, Miguel" uniqKey="Tortajada Girbes M" first="Miguel" last="Tortajada-Girbés">Miguel Tortajada-Girbés</name>
</country>
</tree>
</affiliations>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Sante/explor/GrippeEspagneV1/Data/Main/Exploration

HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000030 | SxmlIndent | more

HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000030 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Sante
   |area=    GrippeEspagneV1
   |flux=    Main
   |étape=   Exploration
   |type=    RBID
   |clé=     pubmed:31387672
   |texte=   Influenza vaccine effectiveness against laboratory-confirmed influenza in hospitalised adults aged 60 years or older, Valencia Region, Spain, 2017/18 influenza season.
}}

Pour générer des pages wiki

HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i   -Sk "pubmed:31387672" \
       | HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd   \
       | NlmPubMed2Wicri -a GrippeEspagneV1

This area was generated with Dilib version V0.6.37.
Data generation: Fri Sep 25 11:01:38 2020. Site generation: Sat Feb 13 17:38:04 2021

	Serveur d'exploration sur la grippe en Espagne
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.

Serveur d'exploration sur la grippe en Espagne

Influenza vaccine effectiveness against laboratory-confirmed influenza in hospitalised adults aged 60 years or older, Valencia Region, Spain, 2017/18 influenza season.

Influenza vaccine effectiveness against laboratory-confirmed influenza in hospitalised adults aged 60 years or older, Valencia Region, Spain, 2017/18 influenza season.

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Abstract

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