Prognostic Implications of Influenza Virus Infection in a Cardiac Intensive Care Unit: Potential Impact of a Screening Program.
Identifieur interne : 000023 ( Main/Exploration ); précédent : 000022; suivant : 000024Prognostic Implications of Influenza Virus Infection in a Cardiac Intensive Care Unit: Potential Impact of a Screening Program.
Auteurs : Patricia Mu Oz [Espagne] ; Lourdes Vicent [Espagne] ; Emilio Bouza [Espagne] ; Iago Sousa-Casasnovas [Espagne] ; Paula L Pez-Roa [Espagne] ; Miriam Juárez [Espagne] ; Alia Eworo [Espagne] ; Carolina Devesa [Espagne] ; Vanesa Bru A [Espagne] ; Pilar Catalán [Espagne] ; Francisco Fernández-Avilés [Espagne] ; Manuel Martínez-Sellés [Espagne]Source :
- Cardiology [ 1421-9751 ]
Descripteurs français
- KwdFr :
- Enregistrements (MeSH), Espagne (épidémiologie), Femelle (MeSH), Grippe humaine (épidémiologie), Humains (MeSH), Incidence (MeSH), Mortalité hospitalière (MeSH), Mâle (MeSH), Sujet âgé (MeSH), Sujet âgé de 80 ans ou plus (MeSH), Unités de soins intensifs cardiaques (statistiques et données numériques), Études prospectives (MeSH).
- MESH :
- statistiques et données numériques : Unités de soins intensifs cardiaques.
- épidémiologie : Espagne, Grippe humaine.
- Enregistrements, Femelle, Humains, Incidence, Mortalité hospitalière, Mâle, Sujet âgé, Sujet âgé de 80 ans ou plus, Études prospectives.
- Wicri :
- geographic : Espagne.
English descriptors
- KwdEn :
- MESH :
- geographic , epidemiology : Spain.
- epidemiology : Influenza, Human.
- statistics & numerical data : Coronary Care Units.
- Aged, Aged, 80 and over, Female, Hospital Mortality, Humans, Incidence, Male, Prospective Studies, Registries.
Abstract
OBJECTIVES
Our goal was to determine the presentation and prognosis of influenza in an intensive cardiac care unit and to analyze the impact of an active surveillance program in the diagnosis.
METHODS
We performed a prospective registry during the flu season in a coronary unit. In the first phase, no systematic screening was performed. Systematic influenza A and B detection was performed in a second phase for all patients admitted.
RESULTS
From 227 patients, we identified 17 (7.5%) with influenza. Influenza patients were more likely to have a non-ischemic cause of admission (14 patients [82.4%] vs. 48 patients [40.3%], p = 0.002), fever (8 patients [47.1%] vs. 3 patients [2.6%], p < 0.001), and respiratory failure (7 patients [41.2%] vs. 8 patients [7%], p = 0.001). Influenza infection was an independent predictor of mortality (odds ratio 12.0, 95% confidence interval 1.9-13.6, p < 0.001). The incidence of influenza was 6.6% (6 patients) when no active screening was performed and 7.9% (11 patients) when systematic detection was performed (p = 0.005). The time to diagnosis was shorter in the systematic screening phase (0.92 ± 1.6 vs. 5.2 ± 3.8 days, p = 0.01).
CONCLUSIONS
Influenza affects approximately 8% of patients admitted to an intensive cardiac care unit during the flu season, with a high mortality rate. An active surveillance program improves early detection.
DOI: 10.1159/000501230
PubMed: 31514195
Affiliations:
Links toward previous steps (curation, corpus...)
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type="city">Madrid</settlement><region nuts="2" type="region">Communauté de Madrid</region></placeName></affiliation></author><author><name sortKey="Fernandez Aviles, Francisco" sort="Fernandez Aviles, Francisco" uniqKey="Fernandez Aviles F" first="Francisco" last="Fernández-Avilés">Francisco Fernández-Avilés</name><affiliation wicri:level="3"><nlm:affiliation>Servicio de Cardiología, Hospital General Universitario Gregorio Marañón, CIBERCV, Madrid, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Servicio de Cardiología, Hospital General Universitario Gregorio Marañón, CIBERCV, Madrid</wicri:regionArea><placeName><settlement type="city">Madrid</settlement><region nuts="2" type="region">Communauté de Madrid</region></placeName></affiliation></author><author><name sortKey="Martinez Selles, Manuel" sort="Martinez Selles, Manuel" uniqKey="Martinez Selles M" first="Manuel" last="Martínez-Sellés">Manuel Martínez-Sellés</name><affiliation wicri:level="1"><nlm:affiliation>Departamento de Medicina. Universidad Complutense, Madrid, Spain, mmselles@secardiologia.es.</nlm:affiliation><country wicri:rule="url">Espagne</country><wicri:regionArea>Departamento de Medicina. Universidad Complutense, Madrid, Spain</wicri:regionArea><wicri:noRegion>Spain</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>Servicio de Cardiología, Hospital General Universitario Gregorio Marañón, CIBERCV, Madrid, Spain, mmselles@secardiologia.es.</nlm:affiliation><country wicri:rule="url">Espagne</country><wicri:regionArea>Servicio de Cardiología, Hospital General Universitario Gregorio Marañón, CIBERCV, Madrid, Spain</wicri:regionArea><wicri:noRegion>Spain</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>Universidad Europea, Madrid, Spain, mmselles@secardiologia.es.</nlm:affiliation><country wicri:rule="url">Espagne</country><wicri:regionArea>Universidad Europea, Madrid, Spain</wicri:regionArea><wicri:noRegion>Spain</wicri:noRegion></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2019">2019</date><idno type="RBID">pubmed:31514195</idno><idno type="pmid">31514195</idno><idno type="doi">10.1159/000501230</idno><idno type="wicri:Area/Main/Corpus">00006</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Corpus" wicri:corpus="PubMed">00006</idno><idno type="wicri:Area/Main/Curation">000006</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Curation">000006</idno><idno type="wicri:Area/Main/Exploration">000006</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Prognostic Implications of Influenza Virus Infection in a Cardiac Intensive Care Unit: Potential Impact of a Screening Program.</title><author><name sortKey="Mu Oz, Patricia" sort="Mu Oz, Patricia" uniqKey="Mu Oz P" first="Patricia" last="Mu Oz">Patricia Mu Oz</name><affiliation wicri:level="3"><nlm:affiliation>Servicio de Microbiología Clínica y Enfermedades Infecciosas, Hospital General Universitario Gregorio Marañón, Madrid, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Servicio de Microbiología Clínica y Enfermedades Infecciosas, Hospital General Universitario Gregorio Marañón, Madrid</wicri:regionArea><placeName><settlement type="city">Madrid</settlement><region nuts="2" type="region">Communauté de Madrid</region></placeName></affiliation><affiliation wicri:level="3"><nlm:affiliation>Instituto de Investigación Sanitaria Hospital Gregorio Marañón, Madrid, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Instituto de Investigación Sanitaria Hospital Gregorio Marañón, Madrid</wicri:regionArea><placeName><settlement type="city">Madrid</settlement><region nuts="2" type="region">Communauté de Madrid</region></placeName></affiliation><affiliation wicri:level="3"><nlm:affiliation>Departamento de Medicina. Universidad Complutense, Madrid, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Departamento de Medicina. Universidad Complutense, Madrid</wicri:regionArea><placeName><settlement type="city">Madrid</settlement><region nuts="2" type="region">Communauté de Madrid</region></placeName></affiliation><affiliation wicri:level="3"><nlm:affiliation>CIBER Enfermedades Respiratorias, CIBERES (CB06/06/0058), Madrid, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>CIBER Enfermedades Respiratorias, CIBERES (CB06/06/0058), Madrid</wicri:regionArea><placeName><settlement type="city">Madrid</settlement><region nuts="2" type="region">Communauté de Madrid</region></placeName></affiliation></author><author><name sortKey="Vicent, Lourdes" sort="Vicent, Lourdes" uniqKey="Vicent L" first="Lourdes" last="Vicent">Lourdes Vicent</name><affiliation wicri:level="3"><nlm:affiliation>Servicio de Cardiología, Hospital General Universitario Gregorio Marañón, CIBERCV, Madrid, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Servicio de Cardiología, Hospital General Universitario Gregorio Marañón, CIBERCV, Madrid</wicri:regionArea><placeName><settlement type="city">Madrid</settlement><region nuts="2" type="region">Communauté de Madrid</region></placeName></affiliation></author><author><name sortKey="Bouza, Emilio" sort="Bouza, Emilio" uniqKey="Bouza E" first="Emilio" last="Bouza">Emilio Bouza</name><affiliation wicri:level="3"><nlm:affiliation>Servicio de Microbiología Clínica y Enfermedades Infecciosas, Hospital General Universitario Gregorio Marañón, Madrid, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Servicio de Microbiología Clínica y Enfermedades Infecciosas, Hospital General Universitario Gregorio Marañón, Madrid</wicri:regionArea><placeName><settlement type="city">Madrid</settlement><region nuts="2" type="region">Communauté de Madrid</region></placeName></affiliation><affiliation wicri:level="3"><nlm:affiliation>Instituto de Investigación Sanitaria Hospital Gregorio Marañón, Madrid, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Instituto de Investigación Sanitaria Hospital Gregorio Marañón, Madrid</wicri:regionArea><placeName><settlement type="city">Madrid</settlement><region nuts="2" type="region">Communauté de Madrid</region></placeName></affiliation><affiliation wicri:level="3"><nlm:affiliation>Departamento de Medicina. Universidad Complutense, Madrid, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Departamento de Medicina. Universidad Complutense, Madrid</wicri:regionArea><placeName><settlement type="city">Madrid</settlement><region nuts="2" type="region">Communauté de Madrid</region></placeName></affiliation><affiliation wicri:level="3"><nlm:affiliation>CIBER Enfermedades Respiratorias, CIBERES (CB06/06/0058), Madrid, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>CIBER Enfermedades Respiratorias, CIBERES (CB06/06/0058), Madrid</wicri:regionArea><placeName><settlement type="city">Madrid</settlement><region nuts="2" type="region">Communauté de Madrid</region></placeName></affiliation></author><author><name sortKey="Sousa Casasnovas, Iago" sort="Sousa Casasnovas, Iago" uniqKey="Sousa Casasnovas I" first="Iago" last="Sousa-Casasnovas">Iago Sousa-Casasnovas</name><affiliation wicri:level="3"><nlm:affiliation>Servicio de Cardiología, Hospital General Universitario Gregorio Marañón, CIBERCV, Madrid, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Servicio de Cardiología, Hospital General Universitario Gregorio Marañón, CIBERCV, Madrid</wicri:regionArea><placeName><settlement type="city">Madrid</settlement><region nuts="2" type="region">Communauté de Madrid</region></placeName></affiliation></author><author><name sortKey="L Pez Roa, Paula" sort="L Pez Roa, Paula" uniqKey="L Pez Roa P" first="Paula" last="L Pez-Roa">Paula L Pez-Roa</name><affiliation wicri:level="3"><nlm:affiliation>Servicio de Microbiología Clínica y Enfermedades Infecciosas, Hospital General Universitario Gregorio Marañón, Madrid, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Servicio de Microbiología Clínica y Enfermedades Infecciosas, Hospital General Universitario Gregorio Marañón, Madrid</wicri:regionArea><placeName><settlement type="city">Madrid</settlement><region nuts="2" type="region">Communauté de Madrid</region></placeName></affiliation></author><author><name sortKey="Juarez, Miriam" sort="Juarez, Miriam" uniqKey="Juarez M" first="Miriam" last="Juárez">Miriam Juárez</name><affiliation wicri:level="3"><nlm:affiliation>Servicio de Cardiología, Hospital General Universitario Gregorio Marañón, CIBERCV, Madrid, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Servicio de Cardiología, Hospital General Universitario Gregorio Marañón, CIBERCV, Madrid</wicri:regionArea><placeName><settlement type="city">Madrid</settlement><region nuts="2" type="region">Communauté de Madrid</region></placeName></affiliation></author><author><name sortKey="Eworo, Alia" sort="Eworo, Alia" uniqKey="Eworo A" first="Alia" last="Eworo">Alia Eworo</name><affiliation wicri:level="3"><nlm:affiliation>Servicio de Microbiología Clínica y Enfermedades Infecciosas, Hospital General Universitario Gregorio Marañón, Madrid, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Servicio de Microbiología Clínica y Enfermedades Infecciosas, Hospital General Universitario Gregorio Marañón, Madrid</wicri:regionArea><placeName><settlement type="city">Madrid</settlement><region nuts="2" type="region">Communauté de Madrid</region></placeName></affiliation></author><author><name sortKey="Devesa, Carolina" sort="Devesa, Carolina" uniqKey="Devesa C" first="Carolina" last="Devesa">Carolina Devesa</name><affiliation wicri:level="3"><nlm:affiliation>Servicio de Cardiología, Hospital General Universitario Gregorio Marañón, CIBERCV, Madrid, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Servicio de Cardiología, Hospital General Universitario Gregorio Marañón, CIBERCV, Madrid</wicri:regionArea><placeName><settlement type="city">Madrid</settlement><region nuts="2" type="region">Communauté de Madrid</region></placeName></affiliation></author><author><name sortKey="Bru A, Vanesa" sort="Bru A, Vanesa" uniqKey="Bru A V" first="Vanesa" last="Bru A">Vanesa Bru A</name><affiliation wicri:level="3"><nlm:affiliation>Servicio de Cardiología, Hospital General Universitario Gregorio Marañón, CIBERCV, Madrid, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Servicio de Cardiología, Hospital General Universitario Gregorio Marañón, CIBERCV, Madrid</wicri:regionArea><placeName><settlement type="city">Madrid</settlement><region nuts="2" type="region">Communauté de Madrid</region></placeName></affiliation></author><author><name sortKey="Catalan, Pilar" sort="Catalan, Pilar" uniqKey="Catalan P" first="Pilar" last="Catalán">Pilar Catalán</name><affiliation wicri:level="3"><nlm:affiliation>Servicio de Microbiología Clínica y Enfermedades Infecciosas, Hospital General Universitario Gregorio Marañón, Madrid, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Servicio de Microbiología Clínica y Enfermedades Infecciosas, Hospital General Universitario Gregorio Marañón, Madrid</wicri:regionArea><placeName><settlement type="city">Madrid</settlement><region nuts="2" type="region">Communauté de Madrid</region></placeName></affiliation></author><author><name sortKey="Fernandez Aviles, Francisco" sort="Fernandez Aviles, Francisco" uniqKey="Fernandez Aviles F" first="Francisco" last="Fernández-Avilés">Francisco Fernández-Avilés</name><affiliation wicri:level="3"><nlm:affiliation>Servicio de Cardiología, Hospital General Universitario Gregorio Marañón, CIBERCV, Madrid, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Servicio de Cardiología, Hospital General Universitario Gregorio Marañón, CIBERCV, Madrid</wicri:regionArea><placeName><settlement type="city">Madrid</settlement><region nuts="2" type="region">Communauté de Madrid</region></placeName></affiliation></author><author><name sortKey="Martinez Selles, Manuel" sort="Martinez Selles, Manuel" uniqKey="Martinez Selles M" first="Manuel" last="Martínez-Sellés">Manuel Martínez-Sellés</name><affiliation wicri:level="1"><nlm:affiliation>Departamento de Medicina. Universidad Complutense, Madrid, Spain, mmselles@secardiologia.es.</nlm:affiliation><country wicri:rule="url">Espagne</country><wicri:regionArea>Departamento de Medicina. Universidad Complutense, Madrid, Spain</wicri:regionArea><wicri:noRegion>Spain</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>Servicio de Cardiología, Hospital General Universitario Gregorio Marañón, CIBERCV, Madrid, Spain, mmselles@secardiologia.es.</nlm:affiliation><country wicri:rule="url">Espagne</country><wicri:regionArea>Servicio de Cardiología, Hospital General Universitario Gregorio Marañón, CIBERCV, Madrid, Spain</wicri:regionArea><wicri:noRegion>Spain</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>Universidad Europea, Madrid, Spain, mmselles@secardiologia.es.</nlm:affiliation><country wicri:rule="url">Espagne</country><wicri:regionArea>Universidad Europea, Madrid, Spain</wicri:regionArea><wicri:noRegion>Spain</wicri:noRegion></affiliation></author></analytic><series><title level="j">Cardiology</title><idno type="eISSN">1421-9751</idno></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Aged (MeSH)</term><term>Aged, 80 and over (MeSH)</term><term>Coronary Care Units (statistics & numerical data)</term><term>Female (MeSH)</term><term>Hospital Mortality (MeSH)</term><term>Humans (MeSH)</term><term>Incidence (MeSH)</term><term>Influenza, Human (epidemiology)</term><term>Male (MeSH)</term><term>Prospective Studies (MeSH)</term><term>Registries (MeSH)</term><term>Spain (epidemiology)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Enregistrements (MeSH)</term><term>Espagne (épidémiologie)</term><term>Femelle (MeSH)</term><term>Grippe humaine (épidémiologie)</term><term>Humains (MeSH)</term><term>Incidence (MeSH)</term><term>Mortalité hospitalière (MeSH)</term><term>Mâle (MeSH)</term><term>Sujet âgé (MeSH)</term><term>Sujet âgé de 80 ans ou plus (MeSH)</term><term>Unités de soins intensifs cardiaques (statistiques et données numériques)</term><term>Études prospectives (MeSH)</term></keywords><keywords scheme="MESH" type="geographic" qualifier="epidemiology" xml:lang="en"><term>Spain</term></keywords><keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Influenza, Human</term></keywords><keywords scheme="MESH" qualifier="statistics & numerical data" xml:lang="en"><term>Coronary Care Units</term></keywords><keywords scheme="MESH" qualifier="statistiques et données numériques" xml:lang="fr"><term>Unités de soins intensifs cardiaques</term></keywords><keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr"><term>Espagne</term><term>Grippe humaine</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Aged</term><term>Aged, 80 and over</term><term>Female</term><term>Hospital Mortality</term><term>Humans</term><term>Incidence</term><term>Male</term><term>Prospective Studies</term><term>Registries</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Enregistrements</term><term>Femelle</term><term>Humains</term><term>Incidence</term><term>Mortalité hospitalière</term><term>Mâle</term><term>Sujet âgé</term><term>Sujet âgé de 80 ans ou plus</term><term>Études prospectives</term></keywords><keywords scheme="Wicri" type="geographic" xml:lang="fr"><term>Espagne</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p><b>OBJECTIVES</b></p><p>Our goal was to determine the presentation and prognosis of influenza in an intensive cardiac care unit and to analyze the impact of an active surveillance program in the diagnosis.</p></div><div type="abstract" xml:lang="en"><p><b>METHODS</b></p><p>We performed a prospective registry during the flu season in a coronary unit. In the first phase, no systematic screening was performed. Systematic influenza A and B detection was performed in a second phase for all patients admitted.</p></div><div type="abstract" xml:lang="en"><p><b>RESULTS</b></p><p>From 227 patients, we identified 17 (7.5%) with influenza. Influenza patients were more likely to have a non-ischemic cause of admission (14 patients [82.4%] vs. 48 patients [40.3%], p = 0.002), fever (8 patients [47.1%] vs. 3 patients [2.6%], p < 0.001), and respiratory failure (7 patients [41.2%] vs. 8 patients [7%], p = 0.001). Influenza infection was an independent predictor of mortality (odds ratio 12.0, 95% confidence interval 1.9-13.6, p < 0.001). The incidence of influenza was 6.6% (6 patients) when no active screening was performed and 7.9% (11 patients) when systematic detection was performed (p = 0.005). The time to diagnosis was shorter in the systematic screening phase (0.92 ± 1.6 vs. 5.2 ± 3.8 days, p = 0.01).</p></div><div type="abstract" xml:lang="en"><p><b>CONCLUSIONS</b></p><p>Influenza affects approximately 8% of patients admitted to an intensive cardiac care unit during the flu season, with a high mortality rate. An active surveillance program improves early detection.</p></div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">31514195</PMID><DateCompleted><Year>2020</Year><Month>02</Month><Day>14</Day></DateCompleted><DateRevised><Year>2020</Year><Month>02</Month><Day>14</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1421-9751</ISSN><JournalIssue CitedMedium="Internet"><Volume>143</Volume><Issue>3-4</Issue><PubDate><MedlineDate>2019</MedlineDate></PubDate></JournalIssue><Title>Cardiology</Title><ISOAbbreviation>Cardiology</ISOAbbreviation></Journal><ArticleTitle>Prognostic Implications of Influenza Virus Infection in a Cardiac Intensive Care Unit: Potential Impact of a Screening Program.</ArticleTitle><Pagination><MedlinePgn>85-91</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1159/000501230</ELocationID><Abstract><AbstractText Label="OBJECTIVES" NlmCategory="OBJECTIVE">Our goal was to determine the presentation and prognosis of influenza in an intensive cardiac care unit and to analyze the impact of an active surveillance program in the diagnosis.</AbstractText><AbstractText Label="METHODS" NlmCategory="METHODS">We performed a prospective registry during the flu season in a coronary unit. In the first phase, no systematic screening was performed. Systematic influenza A and B detection was performed in a second phase for all patients admitted.</AbstractText><AbstractText Label="RESULTS" NlmCategory="RESULTS">From 227 patients, we identified 17 (7.5%) with influenza. Influenza patients were more likely to have a non-ischemic cause of admission (14 patients [82.4%] vs. 48 patients [40.3%], p = 0.002), fever (8 patients [47.1%] vs. 3 patients [2.6%], p < 0.001), and respiratory failure (7 patients [41.2%] vs. 8 patients [7%], p = 0.001). Influenza infection was an independent predictor of mortality (odds ratio 12.0, 95% confidence interval 1.9-13.6, p < 0.001). The incidence of influenza was 6.6% (6 patients) when no active screening was performed and 7.9% (11 patients) when systematic detection was performed (p = 0.005). The time to diagnosis was shorter in the systematic screening phase (0.92 ± 1.6 vs. 5.2 ± 3.8 days, p = 0.01).</AbstractText><AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">Influenza affects approximately 8% of patients admitted to an intensive cardiac care unit during the flu season, with a high mortality rate. An active surveillance program improves early detection.</AbstractText><CopyrightInformation>© 2019 S. Karger AG, Basel.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Muñoz</LastName><ForeName>Patricia</ForeName><Initials>P</Initials><AffiliationInfo><Affiliation>Servicio de Microbiología Clínica y Enfermedades Infecciosas, Hospital General Universitario Gregorio Marañón, Madrid, Spain.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Instituto de Investigación Sanitaria Hospital Gregorio Marañón, Madrid, Spain.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Departamento de Medicina. Universidad Complutense, Madrid, Spain.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>CIBER Enfermedades Respiratorias, CIBERES (CB06/06/0058), Madrid, Spain.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Vicent</LastName><ForeName>Lourdes</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>Servicio de Cardiología, Hospital General Universitario Gregorio Marañón, CIBERCV, Madrid, Spain.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Bouza</LastName><ForeName>Emilio</ForeName><Initials>E</Initials><AffiliationInfo><Affiliation>Servicio de Microbiología Clínica y Enfermedades Infecciosas, Hospital General Universitario Gregorio Marañón, Madrid, Spain.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Instituto de Investigación Sanitaria Hospital Gregorio Marañón, Madrid, Spain.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Departamento de Medicina. Universidad Complutense, Madrid, Spain.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>CIBER Enfermedades Respiratorias, CIBERES (CB06/06/0058), Madrid, Spain.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Sousa-Casasnovas</LastName><ForeName>Iago</ForeName><Initials>I</Initials><AffiliationInfo><Affiliation>Servicio de Cardiología, Hospital General Universitario Gregorio Marañón, CIBERCV, Madrid, Spain.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>López-Roa</LastName><ForeName>Paula</ForeName><Initials>P</Initials><AffiliationInfo><Affiliation>Servicio de Microbiología Clínica y Enfermedades Infecciosas, Hospital General Universitario Gregorio Marañón, Madrid, Spain.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Juárez</LastName><ForeName>Miriam</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Servicio de Cardiología, Hospital General Universitario Gregorio Marañón, CIBERCV, Madrid, Spain.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Eworo</LastName><ForeName>Alia</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Servicio de Microbiología Clínica y Enfermedades Infecciosas, Hospital General Universitario Gregorio Marañón, Madrid, Spain.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Devesa</LastName><ForeName>Carolina</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>Servicio de Cardiología, Hospital General Universitario Gregorio Marañón, CIBERCV, Madrid, Spain.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Bruña</LastName><ForeName>Vanesa</ForeName><Initials>V</Initials><AffiliationInfo><Affiliation>Servicio de Cardiología, Hospital General Universitario Gregorio Marañón, CIBERCV, Madrid, Spain.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Catalán</LastName><ForeName>Pilar</ForeName><Initials>P</Initials><AffiliationInfo><Affiliation>Servicio de Microbiología Clínica y Enfermedades Infecciosas, Hospital General Universitario Gregorio Marañón, Madrid, Spain.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Fernández-Avilés</LastName><ForeName>Francisco</ForeName><Initials>F</Initials><AffiliationInfo><Affiliation>Servicio de Cardiología, Hospital General Universitario Gregorio Marañón, CIBERCV, Madrid, Spain.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Martínez-Sellés</LastName><ForeName>Manuel</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Departamento de Medicina. Universidad Complutense, Madrid, Spain, mmselles@secardiologia.es.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Servicio de Cardiología, Hospital General Universitario Gregorio Marañón, CIBERCV, Madrid, Spain, mmselles@secardiologia.es.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Universidad Europea, Madrid, Spain, mmselles@secardiologia.es.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2019</Year><Month>09</Month><Day>12</Day></ArticleDate></Article><MedlineJournalInfo><Country>Switzerland</Country><MedlineTA>Cardiology</MedlineTA><NlmUniqueID>1266406</NlmUniqueID><ISSNLinking>0008-6312</ISSNLinking></MedlineJournalInfo><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000368" MajorTopicYN="N">Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000369" MajorTopicYN="N">Aged, 80 and over</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D003325" MajorTopicYN="N">Coronary Care Units</DescriptorName><QualifierName UI="Q000706" MajorTopicYN="Y">statistics & numerical data</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D017052" MajorTopicYN="N">Hospital Mortality</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D015994" MajorTopicYN="N">Incidence</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D007251" MajorTopicYN="N">Influenza, Human</DescriptorName><QualifierName UI="Q000453" MajorTopicYN="Y">epidemiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D011446" MajorTopicYN="N">Prospective Studies</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D012042" MajorTopicYN="Y">Registries</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D013030" MajorTopicYN="N" Type="Geographic">Spain</DescriptorName><QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName></MeshHeading></MeshHeadingList><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">Cardiac intensive care unit</Keyword><Keyword MajorTopicYN="N">Influenza</Keyword><Keyword MajorTopicYN="N">Screening</Keyword></KeywordList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2018</Year><Month>08</Month><Day>20</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2019</Year><Month>05</Month><Day>27</Day></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2019</Year><Month>9</Month><Day>13</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2020</Year><Month>2</Month><Day>15</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2019</Year><Month>9</Month><Day>13</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">31514195</ArticleId><ArticleId IdType="pii">000501230</ArticleId><ArticleId IdType="doi">10.1159/000501230</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>Espagne</li></country><region><li>Communauté de Madrid</li></region><settlement><li>Madrid</li></settlement></list><tree><country name="Espagne"><region name="Communauté de Madrid"><name sortKey="Mu Oz, Patricia" sort="Mu Oz, Patricia" uniqKey="Mu Oz P" first="Patricia" last="Mu Oz">Patricia Mu Oz</name></region><name sortKey="Bouza, Emilio" sort="Bouza, Emilio" uniqKey="Bouza E" first="Emilio" last="Bouza">Emilio Bouza</name><name sortKey="Bouza, Emilio" sort="Bouza, Emilio" uniqKey="Bouza E" first="Emilio" last="Bouza">Emilio Bouza</name><name sortKey="Bouza, Emilio" sort="Bouza, Emilio" uniqKey="Bouza E" first="Emilio" last="Bouza">Emilio Bouza</name><name sortKey="Bouza, Emilio" sort="Bouza, Emilio" uniqKey="Bouza E" first="Emilio" last="Bouza">Emilio Bouza</name><name sortKey="Bru A, Vanesa" sort="Bru A, Vanesa" uniqKey="Bru A V" first="Vanesa" last="Bru A">Vanesa Bru A</name><name sortKey="Catalan, Pilar" sort="Catalan, Pilar" uniqKey="Catalan P" first="Pilar" last="Catalán">Pilar Catalán</name><name sortKey="Devesa, Carolina" sort="Devesa, Carolina" uniqKey="Devesa C" first="Carolina" last="Devesa">Carolina Devesa</name><name sortKey="Eworo, Alia" sort="Eworo, Alia" uniqKey="Eworo A" first="Alia" last="Eworo">Alia Eworo</name><name sortKey="Fernandez Aviles, Francisco" sort="Fernandez Aviles, Francisco" uniqKey="Fernandez Aviles F" first="Francisco" last="Fernández-Avilés">Francisco Fernández-Avilés</name><name sortKey="Juarez, Miriam" sort="Juarez, Miriam" uniqKey="Juarez M" first="Miriam" last="Juárez">Miriam Juárez</name><name sortKey="L Pez Roa, Paula" sort="L Pez Roa, Paula" uniqKey="L Pez Roa P" first="Paula" last="L Pez-Roa">Paula L Pez-Roa</name><name sortKey="Martinez Selles, Manuel" sort="Martinez Selles, Manuel" uniqKey="Martinez Selles M" first="Manuel" last="Martínez-Sellés">Manuel Martínez-Sellés</name><name sortKey="Martinez Selles, Manuel" sort="Martinez Selles, Manuel" uniqKey="Martinez Selles M" first="Manuel" last="Martínez-Sellés">Manuel Martínez-Sellés</name><name sortKey="Martinez Selles, Manuel" sort="Martinez Selles, Manuel" uniqKey="Martinez Selles M" first="Manuel" last="Martínez-Sellés">Manuel Martínez-Sellés</name><name sortKey="Mu Oz, Patricia" sort="Mu Oz, Patricia" uniqKey="Mu Oz P" first="Patricia" last="Mu Oz">Patricia Mu Oz</name><name sortKey="Mu Oz, Patricia" sort="Mu Oz, Patricia" uniqKey="Mu Oz P" first="Patricia" last="Mu Oz">Patricia Mu Oz</name><name sortKey="Mu Oz, Patricia" sort="Mu Oz, Patricia" uniqKey="Mu Oz P" first="Patricia" last="Mu Oz">Patricia Mu Oz</name><name sortKey="Sousa Casasnovas, Iago" sort="Sousa Casasnovas, Iago" uniqKey="Sousa Casasnovas I" first="Iago" last="Sousa-Casasnovas">Iago Sousa-Casasnovas</name><name sortKey="Vicent, Lourdes" sort="Vicent, Lourdes" uniqKey="Vicent L" first="Lourdes" last="Vicent">Lourdes Vicent</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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