GrippeEspagneV1, Main, Exploration, bibRecord, 000014

[Child hospital admissions associated with influenza virus infection in 6 Spanish cities (2014-2016)].

Identifieur interne : 000014 ( Main/Exploration ); précédent : 000013; suivant : 000015

[Child hospital admissions associated with influenza virus infection in 6 Spanish cities (2014-2016)].

Auteurs : Javier Arístegui Fernández [Espagne] ; Eduardo González Pérez-Yarza [Espagne] ; María José Mellado Pe A [Espagne] ; Carlos Rodrigo Gonzalo De Liria [Espagne] ; Teresa Hernández Sampelayo [Espagne] ; Juan José García García [Espagne] ; Jesús Ruiz Contreras [Espagne] ; David Moreno Pérez [Espagne] ; Elisa Garrote Llanos [Espagne] ; José Tomás Ramos Amador [Espagne] ; Carlos Gustavo Cilla Eguiluz [Espagne] ; María Méndez Hernández [Espagne]

Source :

Anales de pediatria (Barcelona, Spain : 2003) [ 1695-9531 ] ; 2019.

RBID : pubmed:30055938

Descripteurs français

KwdFr :
- Adolescent (MeSH), Enfant (MeSH), Enfant d'âge préscolaire (MeSH), Espagne (épidémiologie), Femelle (MeSH), Grippe humaine (complications), Grippe humaine (diagnostic), Grippe humaine (prévention et contrôle), Grippe humaine (épidémiologie), Hospitalisation (statistiques et données numériques), Humains (MeSH), Mâle (MeSH), Nourrisson (MeSH), Nouveau-né (MeSH), Santé en zone urbaine (statistiques et données numériques), Vaccination (statistiques et données numériques), Vaccins antigrippaux (MeSH), Virus de la grippe A (MeSH), Virus influenza B (MeSH), Études rétrospectives (MeSH).
MESH :
- diagnostic : Grippe humaine.
- prévention et contrôle : Grippe humaine.
- statistiques et données numériques : Hospitalisation, Santé en zone urbaine, Vaccination.
- épidémiologie : Espagne, Grippe humaine.
- Adolescent, Enfant, Enfant d'âge préscolaire, Femelle, Humains, Mâle, Nourrisson, Nouveau-né, Vaccins antigrippaux, Virus de la grippe A, Virus influenza B, Études rétrospectives.
Wicri :
- geographic : Espagne.

English descriptors

KwdEn :
- Adolescent (MeSH), Child (MeSH), Child, Preschool (MeSH), Female (MeSH), Hospitalization (statistics & numerical data), Humans (MeSH), Infant (MeSH), Infant, Newborn (MeSH), Influenza A virus (MeSH), Influenza B virus (MeSH), Influenza Vaccines (MeSH), Influenza, Human (complications), Influenza, Human (diagnosis), Influenza, Human (epidemiology), Influenza, Human (prevention & control), Male (MeSH), Retrospective Studies (MeSH), Spain (epidemiology), Urban Health (statistics & numerical data), Vaccination (statistics & numerical data).
MESH :
- chemical : Influenza Vaccines.
- geographic , epidemiology : Spain.
- complications : Influenza, Human.
- diagnosis : Influenza, Human.
- epidemiology : Influenza, Human.
- prevention & control : Influenza, Human.
- statistics & numerical data : Hospitalization, Urban Health, Vaccination.
- Adolescent, Child, Child, Preschool, Female, Humans, Infant, Infant, Newborn, Influenza A virus, Influenza B virus, Male, Retrospective Studies.

Abstract

INTRODUCTION

There are only a limited number of studies on the impact of influenza in the Spanish child population. The present work intends to increase this knowledge by studying some key aspects, such as the incidence of hospital admissions, clinic variables, comorbidities, and the vaccination status in the hospitalised children.

METHODS

A retrospective, observational study was conducted by reviewing the medical records of children under 15 years and hospitalised due to community acquired influenza confirmed microbiologically, during 2́flu seasons (2014-2015 and 2015-2016). The study was carried out in 10 hospitals of 6cities, which represent approximately 12% of the Spanish child population.

RESULTS

A total of 907 children were admitted to hospital with main diagnosis of influenza infection (447 <2 years), estimating an average annual rate of hospitalisation incidence of 0.51 cases / 1,000 children (95% CI; 0.48-0.55). Just under half (45%) of the cases had an underlying disease considered a risk factor for severe influenza, and most (74%) had not been vaccinated. The percentage of children with underlying diseases increased with age, from 26% in children <6 months to 74% in children >10 years. Admission to the PICU was required in 10% (92) of the cases, mainly due to acute respiratory failure.

CONCLUSION

Influenza continues to be an important cause of hospitalisation in the Spanish child population. Children <6 months of age and children with underlying diseases make up the majority (> 50%) of the cases. Many of the severe forms of childhood influenza that occur today could be avoided if current vaccination guidelines were met.

DOI: 10.1016/j.anpedi.2018.06.012
PubMed: 30055938

Affiliations:

Links toward previous steps (curation, corpus...)

to stream Main, to step Corpus: 00049
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Le document en format XML

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<country xml:lang="fr">Espagne</country>
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<author><name sortKey="Cilla Eguiluz, Carlos Gustavo" sort="Cilla Eguiluz, Carlos Gustavo" uniqKey="Cilla Eguiluz C" first="Carlos Gustavo" last="Cilla Eguiluz">Carlos Gustavo Cilla Eguiluz</name>
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<author><name sortKey="Mendez Hernandez, Maria" sort="Mendez Hernandez, Maria" uniqKey="Mendez Hernandez M" first="María" last="Méndez Hernández">María Méndez Hernández</name>
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<sourceDesc><biblStruct><analytic><title xml:lang="en">[Child hospital admissions associated with influenza virus infection in 6 Spanish cities (2014-2016)].</title>
<author><name sortKey="Aristegui Fernandez, Javier" sort="Aristegui Fernandez, Javier" uniqKey="Aristegui Fernandez J" first="Javier" last="Arístegui Fernández">Javier Arístegui Fernández</name>
<affiliation wicri:level="1"><nlm:affiliation>Sección de Infectología Pediátrica, Hospital Universitario Basurto, Bilbao, Vizcaya, España; Departamento de Pediatría, Universidad del País Vasco, UPV/EHU, Bilbao, Vizcaya, España. Electronic address: javier.aristegui@ehu.eus.</nlm:affiliation>
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<author><name sortKey="Gonzalez Perez Yarza, Eduardo" sort="Gonzalez Perez Yarza, Eduardo" uniqKey="Gonzalez Perez Yarza E" first="Eduardo" last="González Pérez-Yarza">Eduardo González Pérez-Yarza</name>
<affiliation wicri:level="1"><nlm:affiliation>Departamento de Pediatría, Universidad del País Vasco, UPV/EHU, Bilbao, Vizcaya, España; Servicio de Pediatría, Hospital Universitario Donostia, San Sebastián, Guipúzcoa, España; Centro de Investigación Biomédica en Red, Enfermedades Respiratorias (CIBERES), San Sebastián, Guipúzcoa, España.</nlm:affiliation>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Departamento de Pediatría, Universidad del País Vasco, UPV/EHU, Bilbao, Vizcaya, España; Servicio de Pediatría, Hospital Universitario Donostia, San Sebastián, Guipúzcoa, España; Centro de Investigación Biomédica en Red, Enfermedades Respiratorias (CIBERES), San Sebastián, Guipúzcoa</wicri:regionArea>
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<author><name sortKey="Mellado Pe A, Maria Jose" sort="Mellado Pe A, Maria Jose" uniqKey="Mellado Pe A M" first="María José" last="Mellado Pe A">María José Mellado Pe A</name>
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<author><name sortKey="Rodrigo Gonzalo De Liria, Carlos" sort="Rodrigo Gonzalo De Liria, Carlos" uniqKey="Rodrigo Gonzalo De Liria C" first="Carlos" last="Rodrigo Gonzalo De Liria">Carlos Rodrigo Gonzalo De Liria</name>
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<country xml:lang="fr">Espagne</country>
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<author><name sortKey="Hernandez Sampelayo, Teresa" sort="Hernandez Sampelayo, Teresa" uniqKey="Hernandez Sampelayo T" first="Teresa" last="Hernández Sampelayo">Teresa Hernández Sampelayo</name>
<affiliation wicri:level="3"><nlm:affiliation>Servicio de Pediatría, Hospital General Universitario Gregorio Marañón, Madrid, España.</nlm:affiliation>
<country xml:lang="fr">Espagne</country>
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</placeName>
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<author><name sortKey="Garcia Garcia, Juan Jose" sort="Garcia Garcia, Juan Jose" uniqKey="Garcia Garcia J" first="Juan José" last="García García">Juan José García García</name>
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<country xml:lang="fr">Espagne</country>
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<author><name sortKey="Ruiz Contreras, Jesus" sort="Ruiz Contreras, Jesus" uniqKey="Ruiz Contreras J" first="Jesús" last="Ruiz Contreras">Jesús Ruiz Contreras</name>
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<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Servicio de Pediatría, Hospital Universitario 12 de Octubre, Madrid</wicri:regionArea>
<placeName><settlement type="city">Madrid</settlement>
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<author><name sortKey="Moreno Perez, David" sort="Moreno Perez, David" uniqKey="Moreno Perez D" first="David" last="Moreno Pérez">David Moreno Pérez</name>
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<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Servicio de Pediatría, Hospital Regional Universitario de Málaga, Málaga</wicri:regionArea>
<wicri:noRegion>Málaga</wicri:noRegion>
</affiliation>
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<author><name sortKey="Garrote Llanos, Elisa" sort="Garrote Llanos, Elisa" uniqKey="Garrote Llanos E" first="Elisa" last="Garrote Llanos">Elisa Garrote Llanos</name>
<affiliation wicri:level="1"><nlm:affiliation>Sección de Infectología Pediátrica, Hospital Universitario Basurto, Bilbao, Vizcaya, España; Departamento de Pediatría, Universidad del País Vasco, UPV/EHU, Bilbao, Vizcaya, España.</nlm:affiliation>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Sección de Infectología Pediátrica, Hospital Universitario Basurto, Bilbao, Vizcaya, España; Departamento de Pediatría, Universidad del País Vasco, UPV/EHU, Bilbao, Vizcaya</wicri:regionArea>
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<author><name sortKey="Ramos Amador, Jose Tomas" sort="Ramos Amador, Jose Tomas" uniqKey="Ramos Amador J" first="José Tomás" last="Ramos Amador">José Tomás Ramos Amador</name>
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<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Departamento de Salud Pública y Materno-infantil, Universidad Complutense, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria del Hospital Clínico San Carlos, Madrid</wicri:regionArea>
<placeName><settlement type="city">Madrid</settlement>
<region nuts="2" type="region">Communauté de Madrid</region>
</placeName>
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<author><name sortKey="Cilla Eguiluz, Carlos Gustavo" sort="Cilla Eguiluz, Carlos Gustavo" uniqKey="Cilla Eguiluz C" first="Carlos Gustavo" last="Cilla Eguiluz">Carlos Gustavo Cilla Eguiluz</name>
<affiliation wicri:level="1"><nlm:affiliation>Centro de Investigación Biomédica en Red, Enfermedades Respiratorias (CIBERES), San Sebastián, Guipúzcoa, España; Servicio de Microbiología, Hospital Universitario Donostia, San Sebastián, Guipúzcoa, España.</nlm:affiliation>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Centro de Investigación Biomédica en Red, Enfermedades Respiratorias (CIBERES), San Sebastián, Guipúzcoa, España; Servicio de Microbiología, Hospital Universitario Donostia, San Sebastián, Guipúzcoa</wicri:regionArea>
<wicri:noRegion>Guipúzcoa</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Mendez Hernandez, Maria" sort="Mendez Hernandez, Maria" uniqKey="Mendez Hernandez M" first="María" last="Méndez Hernández">María Méndez Hernández</name>
<affiliation wicri:level="4"><nlm:affiliation>Facultad de Medicina, Unidad Docente Germans Trias i Pujol, Universidad Autónoma de Barcelona, Barcelona, España; Servicio de Pediatría, Hospital Universitario Germans Trias i Pujol, Badalona, Barcelona, España.</nlm:affiliation>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Facultad de Medicina, Unidad Docente Germans Trias i Pujol, Universidad Autónoma de Barcelona, Barcelona, España; Servicio de Pediatría, Hospital Universitario Germans Trias i Pujol, Badalona, Barcelona</wicri:regionArea>
<placeName><settlement type="city">Barcelone</settlement>
<region nuts="2" type="region">Catalogne</region>
</placeName>
<orgName type="university">Université autonome de Barcelone</orgName>
</affiliation>
</author>
</analytic>
<series><title level="j">Anales de pediatria (Barcelona, Spain : 2003)</title>
<idno type="eISSN">1695-9531</idno>
<imprint><date when="2019" type="published">2019</date>
</imprint>
</series>
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</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adolescent (MeSH)</term>
<term>Child (MeSH)</term>
<term>Child, Preschool (MeSH)</term>
<term>Female (MeSH)</term>
<term>Hospitalization (statistics & numerical data)</term>
<term>Humans (MeSH)</term>
<term>Infant (MeSH)</term>
<term>Infant, Newborn (MeSH)</term>
<term>Influenza A virus (MeSH)</term>
<term>Influenza B virus (MeSH)</term>
<term>Influenza Vaccines (MeSH)</term>
<term>Influenza, Human (complications)</term>
<term>Influenza, Human (diagnosis)</term>
<term>Influenza, Human (epidemiology)</term>
<term>Influenza, Human (prevention & control)</term>
<term>Male (MeSH)</term>
<term>Retrospective Studies (MeSH)</term>
<term>Spain (epidemiology)</term>
<term>Urban Health (statistics & numerical data)</term>
<term>Vaccination (statistics & numerical data)</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Adolescent (MeSH)</term>
<term>Enfant (MeSH)</term>
<term>Enfant d'âge préscolaire (MeSH)</term>
<term>Espagne (épidémiologie)</term>
<term>Femelle (MeSH)</term>
<term>Grippe humaine (complications)</term>
<term>Grippe humaine (diagnostic)</term>
<term>Grippe humaine (prévention et contrôle)</term>
<term>Grippe humaine (épidémiologie)</term>
<term>Hospitalisation (statistiques et données numériques)</term>
<term>Humains (MeSH)</term>
<term>Mâle (MeSH)</term>
<term>Nourrisson (MeSH)</term>
<term>Nouveau-né (MeSH)</term>
<term>Santé  en zone urbaine (statistiques et données numériques)</term>
<term>Vaccination (statistiques et données numériques)</term>
<term>Vaccins antigrippaux (MeSH)</term>
<term>Virus de la grippe A (MeSH)</term>
<term>Virus influenza B (MeSH)</term>
<term>Études rétrospectives (MeSH)</term>
</keywords>
<keywords scheme="MESH" type="chemical" xml:lang="en"><term>Influenza Vaccines</term>
</keywords>
<keywords scheme="MESH" type="geographic" qualifier="epidemiology" xml:lang="en"><term>Spain</term>
</keywords>
<keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Influenza, Human</term>
</keywords>
<keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Influenza, Human</term>
</keywords>
<keywords scheme="MESH" qualifier="diagnostic" xml:lang="fr"><term>Grippe humaine</term>
</keywords>
<keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Influenza, Human</term>
</keywords>
<keywords scheme="MESH" qualifier="prevention & control" xml:lang="en"><term>Influenza, Human</term>
</keywords>
<keywords scheme="MESH" qualifier="prévention et contrôle" xml:lang="fr"><term>Grippe humaine</term>
</keywords>
<keywords scheme="MESH" qualifier="statistics & numerical data" xml:lang="en"><term>Hospitalization</term>
<term>Urban Health</term>
<term>Vaccination</term>
</keywords>
<keywords scheme="MESH" qualifier="statistiques et données numériques" xml:lang="fr"><term>Hospitalisation</term>
<term>Santé  en zone urbaine</term>
<term>Vaccination</term>
</keywords>
<keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr"><term>Espagne</term>
<term>Grippe humaine</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Adolescent</term>
<term>Child</term>
<term>Child, Preschool</term>
<term>Female</term>
<term>Humans</term>
<term>Infant</term>
<term>Infant, Newborn</term>
<term>Influenza A virus</term>
<term>Influenza B virus</term>
<term>Male</term>
<term>Retrospective Studies</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>Adolescent</term>
<term>Enfant</term>
<term>Enfant d'âge préscolaire</term>
<term>Femelle</term>
<term>Humains</term>
<term>Mâle</term>
<term>Nourrisson</term>
<term>Nouveau-né</term>
<term>Vaccins antigrippaux</term>
<term>Virus de la grippe A</term>
<term>Virus influenza B</term>
<term>Études rétrospectives</term>
</keywords>
<keywords scheme="Wicri" type="geographic" xml:lang="fr"><term>Espagne</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en"><p><b>INTRODUCTION</b>
</p>
<p>There are only a limited number of studies on the impact of influenza in the Spanish child population. The present work intends to increase this knowledge by studying some key aspects, such as the incidence of hospital admissions, clinic variables, comorbidities, and the vaccination status in the hospitalised children.</p>
</div>
<div type="abstract" xml:lang="en"><p><b>METHODS</b>
</p>
<p>A retrospective, observational study was conducted by reviewing the medical records of children under 15 years and hospitalised due to community acquired influenza confirmed microbiologically, during 2́flu seasons (2014-2015 and 2015-2016). The study was carried out in 10 hospitals of 6cities, which represent approximately 12% of the Spanish child population.</p>
</div>
<div type="abstract" xml:lang="en"><p><b>RESULTS</b>
</p>
<p>A total of 907 children were admitted to hospital with main diagnosis of influenza infection (447 <2 years), estimating an average annual rate of hospitalisation incidence of 0.51 cases / 1,000 children (95% CI; 0.48-0.55). Just under half (45%) of the cases had an underlying disease considered a risk factor for severe influenza, and most (74%) had not been vaccinated. The percentage of children with underlying diseases increased with age, from 26% in children <6 months to 74% in children >10 years. Admission to the PICU was required in 10% (92) of the cases, mainly due to acute respiratory failure.</p>
</div>
<div type="abstract" xml:lang="en"><p><b>CONCLUSION</b>
</p>
<p>Influenza continues to be an important cause of hospitalisation in the Spanish child population. Children <6 months of age and children with underlying diseases make up the majority (> 50%) of the cases. Many of the severe forms of childhood influenza that occur today could be avoided if current vaccination guidelines were met.</p>
</div>
</front>
</TEI>
<pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">30055938</PMID>
<DateCompleted><Year>2019</Year>
<Month>08</Month>
<Day>26</Day>
</DateCompleted>
<DateRevised><Year>2019</Year>
<Month>08</Month>
<Day>26</Day>
</DateRevised>
<Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1695-9531</ISSN>
<JournalIssue CitedMedium="Internet"><Volume>90</Volume>
<Issue>2</Issue>
<PubDate><Year>2019</Year>
<Month>Feb</Month>
</PubDate>
</JournalIssue>
<Title>Anales de pediatria (Barcelona, Spain : 2003)</Title>
<ISOAbbreviation>An Pediatr (Barc)</ISOAbbreviation>
</Journal>
<ArticleTitle>[Child hospital admissions associated with influenza virus infection in 6 Spanish cities (2014-2016)].</ArticleTitle>
<Pagination><MedlinePgn>86-93</MedlinePgn>
</Pagination>
<ELocationID EIdType="pii" ValidYN="Y">S1695-4033(18)30300-X</ELocationID>
<ELocationID EIdType="doi" ValidYN="Y">10.1016/j.anpedi.2018.06.012</ELocationID>
<Abstract><AbstractText Label="INTRODUCTION" NlmCategory="BACKGROUND">There are only a limited number of studies on the impact of influenza in the Spanish child population. The present work intends to increase this knowledge by studying some key aspects, such as the incidence of hospital admissions, clinic variables, comorbidities, and the vaccination status in the hospitalised children.</AbstractText>
<AbstractText Label="METHODS" NlmCategory="METHODS">A retrospective, observational study was conducted by reviewing the medical records of children under 15 years and hospitalised due to community acquired influenza confirmed microbiologically, during 2́flu seasons (2014-2015 and 2015-2016). The study was carried out in 10 hospitals of 6cities, which represent approximately 12% of the Spanish child population.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">A total of 907 children were admitted to hospital with main diagnosis of influenza infection (447 <2 years), estimating an average annual rate of hospitalisation incidence of 0.51 cases / 1,000 children (95% CI; 0.48-0.55). Just under half (45%) of the cases had an underlying disease considered a risk factor for severe influenza, and most (74%) had not been vaccinated. The percentage of children with underlying diseases increased with age, from 26% in children <6 months to 74% in children >10 years. Admission to the PICU was required in 10% (92) of the cases, mainly due to acute respiratory failure.</AbstractText>
<AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">Influenza continues to be an important cause of hospitalisation in the Spanish child population. Children <6 months of age and children with underlying diseases make up the majority (> 50%) of the cases. Many of the severe forms of childhood influenza that occur today could be avoided if current vaccination guidelines were met.</AbstractText>
<CopyrightInformation>Copyright © 2018 Asociación Española de Pediatría. Publicado por Elsevier España, S.L.U. All rights reserved.</CopyrightInformation>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Arístegui Fernández</LastName>
<ForeName>Javier</ForeName>
<Initials>J</Initials>
<AffiliationInfo><Affiliation>Sección de Infectología Pediátrica, Hospital Universitario Basurto, Bilbao, Vizcaya, España; Departamento de Pediatría, Universidad del País Vasco, UPV/EHU, Bilbao, Vizcaya, España. Electronic address: javier.aristegui@ehu.eus.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>González Pérez-Yarza</LastName>
<ForeName>Eduardo</ForeName>
<Initials>E</Initials>
<AffiliationInfo><Affiliation>Departamento de Pediatría, Universidad del País Vasco, UPV/EHU, Bilbao, Vizcaya, España; Servicio de Pediatría, Hospital Universitario Donostia, San Sebastián, Guipúzcoa, España; Centro de Investigación Biomédica en Red, Enfermedades Respiratorias (CIBERES), San Sebastián, Guipúzcoa, España.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Mellado Peña</LastName>
<ForeName>María José</ForeName>
<Initials>MJ</Initials>
<AffiliationInfo><Affiliation>Servicio de Pediatría Hospitalaria, Enfermedades Infecciosas y Tropicales, Hospital Universitario La Paz, Madrid, España.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Rodrigo Gonzalo de Liria</LastName>
<ForeName>Carlos</ForeName>
<Initials>C</Initials>
<AffiliationInfo><Affiliation>Servicio de Pediatría, Hospital Universitario Vall d'Hebron, Barcelona, España; Facultad de Medicina, Unidad Docente Germans Trias i Pujol, Universidad Autónoma de Barcelona, Barcelona, España.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Hernández Sampelayo</LastName>
<ForeName>Teresa</ForeName>
<Initials>T</Initials>
<AffiliationInfo><Affiliation>Servicio de Pediatría, Hospital General Universitario Gregorio Marañón, Madrid, España.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>García García</LastName>
<ForeName>Juan José</ForeName>
<Initials>JJ</Initials>
<AffiliationInfo><Affiliation>Servicio de Pediatría, Hospital Sant Joan de Déu, Universitat de Barcelona, Barcelona, España.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Ruiz Contreras</LastName>
<ForeName>Jesús</ForeName>
<Initials>J</Initials>
<AffiliationInfo><Affiliation>Servicio de Pediatría, Hospital Universitario 12 de Octubre, Madrid, España.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Moreno Pérez</LastName>
<ForeName>David</ForeName>
<Initials>D</Initials>
<AffiliationInfo><Affiliation>Servicio de Pediatría, Hospital Regional Universitario de Málaga, Málaga, España.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Garrote Llanos</LastName>
<ForeName>Elisa</ForeName>
<Initials>E</Initials>
<AffiliationInfo><Affiliation>Sección de Infectología Pediátrica, Hospital Universitario Basurto, Bilbao, Vizcaya, España; Departamento de Pediatría, Universidad del País Vasco, UPV/EHU, Bilbao, Vizcaya, España.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Ramos Amador</LastName>
<ForeName>José Tomás</ForeName>
<Initials>JT</Initials>
<AffiliationInfo><Affiliation>Departamento de Salud Pública y Materno-infantil, Universidad Complutense, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria del Hospital Clínico San Carlos, Madrid, España.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Cilla Eguiluz</LastName>
<ForeName>Carlos Gustavo</ForeName>
<Initials>CG</Initials>
<AffiliationInfo><Affiliation>Centro de Investigación Biomédica en Red, Enfermedades Respiratorias (CIBERES), San Sebastián, Guipúzcoa, España; Servicio de Microbiología, Hospital Universitario Donostia, San Sebastián, Guipúzcoa, España.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Méndez Hernández</LastName>
<ForeName>María</ForeName>
<Initials>M</Initials>
<AffiliationInfo><Affiliation>Facultad de Medicina, Unidad Docente Germans Trias i Pujol, Universidad Autónoma de Barcelona, Barcelona, España; Servicio de Pediatría, Hospital Universitario Germans Trias i Pujol, Badalona, Barcelona, España.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><CollectiveName>en representación del grupo de estudio HOSPIGRIP</CollectiveName>
</Author>
<Author ValidYN="Y"><CollectiveName>Autores del grupo de estudio HOSPIGRIP</CollectiveName>
</Author>
</AuthorList>
<Language>spa</Language>
<PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType>
<PublicationType UI="D016448">Multicenter Study</PublicationType>
<PublicationType UI="D064888">Observational Study</PublicationType>
</PublicationTypeList>
<VernacularTitle>Hospitalizaciones infantiles asociadas a infección por virus de la gripe en 6 ciudades de España (2014-2016).</VernacularTitle>
<ArticleDate DateType="Electronic"><Year>2018</Year>
<Month>07</Month>
<Day>25</Day>
</ArticleDate>
</Article>
<MedlineJournalInfo><Country>Spain</Country>
<MedlineTA>An Pediatr (Barc)</MedlineTA>
<NlmUniqueID>101162596</NlmUniqueID>
<ISSNLinking>1695-4033</ISSNLinking>
</MedlineJournalInfo>
<ChemicalList><Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="D007252">Influenza Vaccines</NameOfSubstance>
</Chemical>
</ChemicalList>
<MeshHeadingList><MeshHeading><DescriptorName UI="D000293" MajorTopicYN="N">Adolescent</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D002648" MajorTopicYN="N">Child</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D002675" MajorTopicYN="N">Child, Preschool</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D006760" MajorTopicYN="N">Hospitalization</DescriptorName>
<QualifierName UI="Q000706" MajorTopicYN="Y">statistics & numerical data</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D007223" MajorTopicYN="N">Infant</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D007231" MajorTopicYN="N">Infant, Newborn</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D009980" MajorTopicYN="Y">Influenza A virus</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D009981" MajorTopicYN="Y">Influenza B virus</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D007252" MajorTopicYN="N">Influenza Vaccines</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D007251" MajorTopicYN="N">Influenza, Human</DescriptorName>
<QualifierName UI="Q000150" MajorTopicYN="N">complications</QualifierName>
<QualifierName UI="Q000175" MajorTopicYN="N">diagnosis</QualifierName>
<QualifierName UI="Q000453" MajorTopicYN="Y">epidemiology</QualifierName>
<QualifierName UI="Q000517" MajorTopicYN="N">prevention & control</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D012189" MajorTopicYN="N">Retrospective Studies</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D013030" MajorTopicYN="N" Type="Geographic">Spain</DescriptorName>
<QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D014504" MajorTopicYN="N">Urban Health</DescriptorName>
<QualifierName UI="Q000706" MajorTopicYN="Y">statistics & numerical data</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D014611" MajorTopicYN="N">Vaccination</DescriptorName>
<QualifierName UI="Q000706" MajorTopicYN="N">statistics & numerical data</QualifierName>
</MeshHeading>
</MeshHeadingList>
<KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">Children</Keyword>
<Keyword MajorTopicYN="N">Hospital admissions</Keyword>
<Keyword MajorTopicYN="N">Hospitalizaciones</Keyword>
<Keyword MajorTopicYN="N">Influenza virus</Keyword>
<Keyword MajorTopicYN="N">Niños</Keyword>
<Keyword MajorTopicYN="N">Virus de la gripe</Keyword>
</KeywordList>
<InvestigatorList><Investigator ValidYN="Y"><LastName>Aristegui</LastName>
<ForeName>J</ForeName>
<Initials>J</Initials>
<AffiliationInfo><Affiliation>Hospitales e investigadores: HU Basurto, Bilbao.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>Garrote</LastName>
<ForeName>E</ForeName>
<Initials>E</Initials>
<AffiliationInfo><Affiliation>Hospitales e investigadores: HU Basurto, Bilbao.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>Larrauri</LastName>
<ForeName>A</ForeName>
<Initials>A</Initials>
<AffiliationInfo><Affiliation>Hospitales e investigadores: HU Basurto, Bilbao.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>Pérez-Yarza</LastName>
<ForeName>E G</ForeName>
<Initials>EG</Initials>
<AffiliationInfo><Affiliation>HU Donostia, San Sebastián.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>Cilla</LastName>
<ForeName>G</ForeName>
<Initials>G</Initials>
<AffiliationInfo><Affiliation>HU Donostia, San Sebastián.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>Unsain</LastName>
<ForeName>M</ForeName>
<Initials>M</Initials>
<AffiliationInfo><Affiliation>HU Donostia, San Sebastián.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>Contreras</LastName>
<ForeName>J Ruiz</ForeName>
<Initials>JR</Initials>
<AffiliationInfo><Affiliation>HU 12 de Octubre, Madrid.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>García-Ochoa</LastName>
<ForeName>E</ForeName>
<Initials>E</Initials>
<AffiliationInfo><Affiliation>HU 12 de Octubre, Madrid.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>Gordillo</LastName>
<ForeName>J C</ForeName>
<Initials>JC</Initials>
<AffiliationInfo><Affiliation>HU 12 de Octubre, Madrid.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>Sampelayo</LastName>
<ForeName>T Hernández</ForeName>
<Initials>TH</Initials>
<AffiliationInfo><Affiliation>HGU Gregorio Marañón, Madrid.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>Rodríguez</LastName>
<ForeName>R</ForeName>
<Initials>R</Initials>
<AffiliationInfo><Affiliation>HGU Gregorio Marañón, Madrid.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>González</LastName>
<ForeName>F</ForeName>
<Initials>F</Initials>
<AffiliationInfo><Affiliation>HGU Gregorio Marañón, Madrid.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>Mellado</LastName>
<ForeName>M J</ForeName>
<Initials>MJ</Initials>
<AffiliationInfo><Affiliation>HU La Paz, Madrid.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>Calvo</LastName>
<ForeName>C</ForeName>
<Initials>C</Initials>
<AffiliationInfo><Affiliation>HU La Paz, Madrid.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>Méndez</LastName>
<ForeName>A</ForeName>
<Initials>A</Initials>
<AffiliationInfo><Affiliation>HU La Paz, Madrid.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>Bustamante</LastName>
<ForeName>J</ForeName>
<Initials>J</Initials>
<AffiliationInfo><Affiliation>HU La Paz, Madrid.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>Salas</LastName>
<ForeName>D</ForeName>
<Initials>D</Initials>
<AffiliationInfo><Affiliation>HU La Paz, Madrid.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>Lacasta</LastName>
<ForeName>C</ForeName>
<Initials>C</Initials>
<AffiliationInfo><Affiliation>HU La Paz, Madrid.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>Ramos</LastName>
<ForeName>J T</ForeName>
<Initials>JT</Initials>
<AffiliationInfo><Affiliation>HU San Carlos, Madrid.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>Illán</LastName>
<ForeName>M</ForeName>
<Initials>M</Initials>
<AffiliationInfo><Affiliation>HU San Carlos, Madrid.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>Mendez</LastName>
<ForeName>M</ForeName>
<Initials>M</Initials>
<AffiliationInfo><Affiliation>HU Germans Trias i Pujol, Badalona.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>Barjuan</LastName>
<ForeName>M</ForeName>
<Initials>M</Initials>
<AffiliationInfo><Affiliation>HU Germans Trias i Pujol, Badalona.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>García</LastName>
<ForeName>J J</ForeName>
<Initials>JJ</Initials>
<AffiliationInfo><Affiliation>HU Sant Joan de Déu, Barcelona.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>Urraca</LastName>
<ForeName>S</ForeName>
<Initials>S</Initials>
<AffiliationInfo><Affiliation>HU Sant Joan de Déu, Barcelona.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>Caballero</LastName>
<ForeName>M</ForeName>
<Initials>M</Initials>
<AffiliationInfo><Affiliation>HU Sant Joan de Déu, Barcelona.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>Launes</LastName>
<ForeName>C</ForeName>
<Initials>C</Initials>
<AffiliationInfo><Affiliation>HU Sant Joan de Déu, Barcelona.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>Rodrigo</LastName>
<ForeName>C</ForeName>
<Initials>C</Initials>
<AffiliationInfo><Affiliation>HU Vall d'Hebron, Barcelona.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>Fàbregas</LastName>
<ForeName>A</ForeName>
<Initials>A</Initials>
<AffiliationInfo><Affiliation>HU Vall d'Hebron, Barcelona.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>Esmel</LastName>
<ForeName>R</ForeName>
<Initials>R</Initials>
<AffiliationInfo><Affiliation>HU Vall d'Hebron, Barcelona.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>Antón</LastName>
<ForeName>A</ForeName>
<Initials>A</Initials>
<AffiliationInfo><Affiliation>HU Vall d'Hebron, Barcelona.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>Moreno</LastName>
<ForeName>D</ForeName>
<Initials>D</Initials>
<AffiliationInfo><Affiliation>HRU de Málaga, Málaga.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>Valdivielso</LastName>
<ForeName>A I</ForeName>
<Initials>AI</Initials>
<AffiliationInfo><Affiliation>HRU de Málaga, Málaga.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>Piñero</LastName>
<ForeName>P</ForeName>
<Initials>P</Initials>
<AffiliationInfo><Affiliation>HRU de Málaga, Málaga.</Affiliation>
</AffiliationInfo>
</Investigator>
<Investigator ValidYN="Y"><LastName>Carazo</LastName>
<ForeName>B</ForeName>
<Initials>B</Initials>
<AffiliationInfo><Affiliation>HRU de Málaga, Málaga.</Affiliation>
</AffiliationInfo>
</Investigator>
</InvestigatorList>
</MedlineCitation>
<PubmedData><History><PubMedPubDate PubStatus="received"><Year>2018</Year>
<Month>05</Month>
<Day>25</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="revised"><Year>2018</Year>
<Month>06</Month>
<Day>21</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="accepted"><Year>2018</Year>
<Month>06</Month>
<Day>22</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="pubmed"><Year>2018</Year>
<Month>7</Month>
<Day>30</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="medline"><Year>2019</Year>
<Month>8</Month>
<Day>27</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="entrez"><Year>2018</Year>
<Month>7</Month>
<Day>30</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
</History>
<PublicationStatus>ppublish</PublicationStatus>
<ArticleIdList><ArticleId IdType="pubmed">30055938</ArticleId>
<ArticleId IdType="pii">S1695-4033(18)30300-X</ArticleId>
<ArticleId IdType="doi">10.1016/j.anpedi.2018.06.012</ArticleId>
</ArticleIdList>
</PubmedData>
</pubmed>
<affiliations><list><country><li>Espagne</li>
</country>
<region><li>Catalogne</li>
<li>Communauté de Madrid</li>
</region>
<settlement><li>Barcelone</li>
<li>Madrid</li>
</settlement>
<orgName><li>Université autonome de Barcelone</li>
<li>Université de Barcelone</li>
</orgName>
</list>
<tree><country name="Espagne"><noRegion><name sortKey="Aristegui Fernandez, Javier" sort="Aristegui Fernandez, Javier" uniqKey="Aristegui Fernandez J" first="Javier" last="Arístegui Fernández">Javier Arístegui Fernández</name>
</noRegion>
<name sortKey="Cilla Eguiluz, Carlos Gustavo" sort="Cilla Eguiluz, Carlos Gustavo" uniqKey="Cilla Eguiluz C" first="Carlos Gustavo" last="Cilla Eguiluz">Carlos Gustavo Cilla Eguiluz</name>
<name sortKey="Garcia Garcia, Juan Jose" sort="Garcia Garcia, Juan Jose" uniqKey="Garcia Garcia J" first="Juan José" last="García García">Juan José García García</name>
<name sortKey="Garrote Llanos, Elisa" sort="Garrote Llanos, Elisa" uniqKey="Garrote Llanos E" first="Elisa" last="Garrote Llanos">Elisa Garrote Llanos</name>
<name sortKey="Gonzalez Perez Yarza, Eduardo" sort="Gonzalez Perez Yarza, Eduardo" uniqKey="Gonzalez Perez Yarza E" first="Eduardo" last="González Pérez-Yarza">Eduardo González Pérez-Yarza</name>
<name sortKey="Hernandez Sampelayo, Teresa" sort="Hernandez Sampelayo, Teresa" uniqKey="Hernandez Sampelayo T" first="Teresa" last="Hernández Sampelayo">Teresa Hernández Sampelayo</name>
<name sortKey="Mellado Pe A, Maria Jose" sort="Mellado Pe A, Maria Jose" uniqKey="Mellado Pe A M" first="María José" last="Mellado Pe A">María José Mellado Pe A</name>
<name sortKey="Mendez Hernandez, Maria" sort="Mendez Hernandez, Maria" uniqKey="Mendez Hernandez M" first="María" last="Méndez Hernández">María Méndez Hernández</name>
<name sortKey="Moreno Perez, David" sort="Moreno Perez, David" uniqKey="Moreno Perez D" first="David" last="Moreno Pérez">David Moreno Pérez</name>
<name sortKey="Ramos Amador, Jose Tomas" sort="Ramos Amador, Jose Tomas" uniqKey="Ramos Amador J" first="José Tomás" last="Ramos Amador">José Tomás Ramos Amador</name>
<name sortKey="Rodrigo Gonzalo De Liria, Carlos" sort="Rodrigo Gonzalo De Liria, Carlos" uniqKey="Rodrigo Gonzalo De Liria C" first="Carlos" last="Rodrigo Gonzalo De Liria">Carlos Rodrigo Gonzalo De Liria</name>
<name sortKey="Ruiz Contreras, Jesus" sort="Ruiz Contreras, Jesus" uniqKey="Ruiz Contreras J" first="Jesús" last="Ruiz Contreras">Jesús Ruiz Contreras</name>
</country>
</tree>
</affiliations>
</record>

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[Child hospital admissions associated with influenza virus infection in 6 Spanish cities (2014-2016)].

[Child hospital admissions associated with influenza virus infection in 6 Spanish cities (2014-2016)].

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