Age-Related Differences in Influenza B Infection by Lineage in a Community-Based Sentinel System, 2010-2011 to 2015-2016, Canada.
Identifieur interne : 000126 ( Main/Exploration ); précédent : 000125; suivant : 000127Age-Related Differences in Influenza B Infection by Lineage in a Community-Based Sentinel System, 2010-2011 to 2015-2016, Canada.
Auteurs : Danuta M. Skowronski [Canada] ; Catharine Chambers ; Gaston De Serres ; Suzana Sabaiduc ; Anne-Luise Winter [Canada] ; James A. Dickinson [Canada] ; Jonathan B. Gubbay [Canada] ; Kevin Fonseca [Canada] ; Steven J. Drews [Canada] ; Hugues Charest ; Christine Martineau ; Mel Krajden [Canada] ; Martin Petric [Canada] ; Nathalie Bastien [Canada] ; Yan Li [Canada]Source :
- The Journal of infectious diseases [ 1537-6613 ] ; 2017.
Descripteurs français
- KwdFr :
- Adolescent (MeSH), Adulte (MeSH), Adulte d'âge moyen (MeSH), Canada (épidémiologie), Enfant (MeSH), Enfant d'âge préscolaire (MeSH), Facteurs âges (MeSH), Grippe humaine (diagnostic), Grippe humaine (épidémiologie), Humains (MeSH), Jeune adulte (MeSH), Nourrisson (MeSH), Nouveau-né (MeSH), Sujet âgé (MeSH), Sujet âgé de 80 ans ou plus (MeSH), Surveillance sentinelle (MeSH), Virus influenza B (isolement et purification), Études cas-témoins (MeSH).
- MESH :
- diagnostic : Grippe humaine.
- isolement et purification : Virus influenza B.
- épidémiologie : Canada, Grippe humaine.
- Adolescent, Adulte, Adulte d'âge moyen, Enfant, Enfant d'âge préscolaire, Facteurs âges, Humains, Jeune adulte, Nourrisson, Nouveau-né, Sujet âgé, Sujet âgé de 80 ans ou plus, Surveillance sentinelle, Études cas-témoins.
English descriptors
- KwdEn :
- Adolescent (MeSH), Adult (MeSH), Age Factors (MeSH), Aged (MeSH), Aged, 80 and over (MeSH), Canada (epidemiology), Case-Control Studies (MeSH), Child (MeSH), Child, Preschool (MeSH), Humans (MeSH), Infant (MeSH), Infant, Newborn (MeSH), Influenza B virus (isolation & purification), Influenza, Human (diagnosis), Influenza, Human (epidemiology), Middle Aged (MeSH), Sentinel Surveillance (MeSH), Young Adult (MeSH).
- MESH :
- diagnosis : Influenza, Human.
- epidemiology : Canada, Influenza, Human.
- isolation & purification : Influenza B virus.
- Adolescent, Adult, Age Factors, Aged, Aged, 80 and over, Case-Control Studies, Child, Child, Preschool, Humans, Infant, Infant, Newborn, Middle Aged, Sentinel Surveillance, Young Adult.
Abstract
Age-related differences in influenza B lineage detection were explored in the community-based Canadian Sentinel Practitioner Surveillance Network (SPSN) from 2010-2011 to 2015-2016. Whereas >80% of B(Victoria) cases were <40 years old, B(Yamagata) cases showed a bimodal age distribution with 27% who were <20 years old and 61% who were 30-64 years old, but with a notable gap in cases between 20 and 29 years old (4%). Overall, the median age was 20 years lower for B(Victoria) vs B(Yamagata) cases (20 vs 40 years; P < .01). Additional phylodynamic and immuno-epidemiological research is needed to understand age-related variation in influenza B risk by lineage, with potential implications for prevention and control across the lifespan.
DOI: 10.1093/infdis/jix393
PubMed: 28934439
PubMed Central: PMC5853978
Affiliations:
- Canada
- Alberta, Colombie-Britannique, Ontario
- Calgary, Edmonton, Toronto, Vancouver
- Université de Calgary
Links toward previous steps (curation, corpus...)
Le document en format XML
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Skowronski</name><affiliation><nlm:affiliation>British Columbia Centre for Disease Control.</nlm:affiliation><wicri:noCountry code="no comma">British Columbia Centre for Disease Control.</wicri:noCountry></affiliation><affiliation wicri:level="3"><nlm:affiliation>University of British Columbia, Vancouver.</nlm:affiliation><country>Canada</country><placeName><settlement type="city">Vancouver</settlement><region type="state">Colombie-Britannique</region></placeName><wicri:orgArea>University of British Columbia</wicri:orgArea></affiliation></author><author><name sortKey="Chambers, Catharine" sort="Chambers, Catharine" uniqKey="Chambers C" first="Catharine" last="Chambers">Catharine Chambers</name><affiliation><nlm:affiliation>British Columbia Centre for Disease Control.</nlm:affiliation><wicri:noCountry code="no comma">British Columbia Centre for Disease Control.</wicri:noCountry></affiliation></author><author><name sortKey="De Serres, Gaston" sort="De Serres, Gaston" uniqKey="De Serres G" first="Gaston" last="De Serres">Gaston De Serres</name><affiliation><nlm:affiliation>Institut National de Santé Publique du Québec.</nlm:affiliation><wicri:noCountry code="no comma">Institut National de Santé Publique du Québec.</wicri:noCountry></affiliation><affiliation><nlm:affiliation>Laval University.</nlm:affiliation><wicri:noCountry code="no comma">Laval University.</wicri:noCountry></affiliation><affiliation><nlm:affiliation>Centre Hospitalier Universitaire de Québec, Québec City.</nlm:affiliation><wicri:noCountry code="subField">Québec City</wicri:noCountry></affiliation></author><author><name sortKey="Sabaiduc, Suzana" sort="Sabaiduc, Suzana" uniqKey="Sabaiduc S" first="Suzana" last="Sabaiduc">Suzana Sabaiduc</name><affiliation><nlm:affiliation>British Columbia Centre for Disease Control.</nlm:affiliation><wicri:noCountry code="no comma">British Columbia Centre for Disease Control.</wicri:noCountry></affiliation></author><author><name sortKey="Winter, Anne Luise" sort="Winter, Anne Luise" uniqKey="Winter A" first="Anne-Luise" last="Winter">Anne-Luise Winter</name><affiliation wicri:level="3"><nlm:affiliation>Public Health Ontario, Toronto.</nlm:affiliation><country>Canada</country><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName><wicri:orgArea>Public Health Ontario</wicri:orgArea></affiliation></author><author><name sortKey="Dickinson, James A" sort="Dickinson, James A" uniqKey="Dickinson J" first="James A" last="Dickinson">James A. 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Drews</name><affiliation wicri:level="3"><nlm:affiliation>Alberta Provincial Laboratory, Edmonton.</nlm:affiliation><country>Canada</country><placeName><settlement type="city">Edmonton</settlement><region type="state">Alberta</region></placeName><wicri:orgArea>Alberta Provincial Laboratory</wicri:orgArea></affiliation><affiliation wicri:level="3"><nlm:affiliation>University of Alberta, Edmonton.</nlm:affiliation><country>Canada</country><placeName><settlement type="city">Edmonton</settlement><region type="state">Alberta</region></placeName><wicri:orgArea>University of Alberta</wicri:orgArea></affiliation></author><author><name sortKey="Charest, Hugues" sort="Charest, Hugues" uniqKey="Charest H" first="Hugues" last="Charest">Hugues Charest</name><affiliation><nlm:affiliation>Institut National de Santé Publique du Québec.</nlm:affiliation><wicri:noCountry code="no comma">Institut National de Santé Publique du Québec.</wicri:noCountry></affiliation></author><author><name sortKey="Martineau, Christine" sort="Martineau, Christine" uniqKey="Martineau C" first="Christine" last="Martineau">Christine Martineau</name><affiliation><nlm:affiliation>Institut National de Santé Publique du Québec.</nlm:affiliation><wicri:noCountry code="no comma">Institut National de Santé Publique du Québec.</wicri:noCountry></affiliation></author><author><name sortKey="Krajden, Mel" sort="Krajden, Mel" uniqKey="Krajden M" first="Mel" last="Krajden">Mel Krajden</name><affiliation><nlm:affiliation>British Columbia Centre for Disease Control.</nlm:affiliation><wicri:noCountry code="no comma">British Columbia Centre for Disease Control.</wicri:noCountry></affiliation><affiliation wicri:level="3"><nlm:affiliation>University of British Columbia, Vancouver.</nlm:affiliation><country>Canada</country><placeName><settlement type="city">Vancouver</settlement><region type="state">Colombie-Britannique</region></placeName><wicri:orgArea>University of British Columbia</wicri:orgArea></affiliation></author><author><name sortKey="Petric, Martin" sort="Petric, Martin" uniqKey="Petric M" first="Martin" last="Petric">Martin Petric</name><affiliation wicri:level="3"><nlm:affiliation>University of British Columbia, Vancouver.</nlm:affiliation><country>Canada</country><placeName><settlement type="city">Vancouver</settlement><region type="state">Colombie-Britannique</region></placeName><wicri:orgArea>University of British Columbia</wicri:orgArea></affiliation></author><author><name sortKey="Bastien, Nathalie" sort="Bastien, Nathalie" uniqKey="Bastien N" first="Nathalie" last="Bastien">Nathalie Bastien</name><affiliation wicri:level="1"><nlm:affiliation>National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Manitoba, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Manitoba</wicri:regionArea><wicri:noRegion>Manitoba</wicri:noRegion></affiliation></author><author><name sortKey="Li, Yan" sort="Li, Yan" uniqKey="Li Y" first="Yan" last="Li">Yan Li</name><affiliation wicri:level="1"><nlm:affiliation>National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Manitoba, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Manitoba</wicri:regionArea><wicri:noRegion>Manitoba</wicri:noRegion></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2017">2017</date><idno type="RBID">pubmed:28934439</idno><idno type="pmid">28934439</idno><idno type="doi">10.1093/infdis/jix393</idno><idno type="pmc">PMC5853978</idno><idno type="wicri:Area/Main/Corpus">000088</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Corpus" wicri:corpus="PubMed">000088</idno><idno type="wicri:Area/Main/Curation">000088</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Curation">000088</idno><idno type="wicri:Area/Main/Exploration">000088</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Age-Related Differences in Influenza B Infection by Lineage in a Community-Based Sentinel System, 2010-2011 to 2015-2016, Canada.</title><author><name sortKey="Skowronski, Danuta M" sort="Skowronski, Danuta M" uniqKey="Skowronski D" first="Danuta M" last="Skowronski">Danuta M. Skowronski</name><affiliation><nlm:affiliation>British Columbia Centre for Disease Control.</nlm:affiliation><wicri:noCountry code="no comma">British Columbia Centre for Disease Control.</wicri:noCountry></affiliation><affiliation wicri:level="3"><nlm:affiliation>University of British Columbia, Vancouver.</nlm:affiliation><country>Canada</country><placeName><settlement type="city">Vancouver</settlement><region type="state">Colombie-Britannique</region></placeName><wicri:orgArea>University of British Columbia</wicri:orgArea></affiliation></author><author><name sortKey="Chambers, Catharine" sort="Chambers, Catharine" uniqKey="Chambers C" first="Catharine" last="Chambers">Catharine Chambers</name><affiliation><nlm:affiliation>British Columbia Centre for Disease Control.</nlm:affiliation><wicri:noCountry code="no comma">British Columbia Centre for Disease Control.</wicri:noCountry></affiliation></author><author><name sortKey="De Serres, Gaston" sort="De Serres, Gaston" uniqKey="De Serres G" first="Gaston" last="De Serres">Gaston De Serres</name><affiliation><nlm:affiliation>Institut National de Santé Publique du Québec.</nlm:affiliation><wicri:noCountry code="no comma">Institut National de Santé Publique du Québec.</wicri:noCountry></affiliation><affiliation><nlm:affiliation>Laval University.</nlm:affiliation><wicri:noCountry code="no comma">Laval University.</wicri:noCountry></affiliation><affiliation><nlm:affiliation>Centre Hospitalier Universitaire de Québec, Québec City.</nlm:affiliation><wicri:noCountry code="subField">Québec City</wicri:noCountry></affiliation></author><author><name sortKey="Sabaiduc, Suzana" sort="Sabaiduc, Suzana" uniqKey="Sabaiduc S" first="Suzana" last="Sabaiduc">Suzana Sabaiduc</name><affiliation><nlm:affiliation>British Columbia Centre for Disease Control.</nlm:affiliation><wicri:noCountry code="no comma">British Columbia Centre for Disease Control.</wicri:noCountry></affiliation></author><author><name sortKey="Winter, Anne Luise" sort="Winter, Anne Luise" uniqKey="Winter A" first="Anne-Luise" last="Winter">Anne-Luise Winter</name><affiliation wicri:level="3"><nlm:affiliation>Public Health Ontario, Toronto.</nlm:affiliation><country>Canada</country><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName><wicri:orgArea>Public Health Ontario</wicri:orgArea></affiliation></author><author><name sortKey="Dickinson, James A" sort="Dickinson, James A" uniqKey="Dickinson J" first="James A" last="Dickinson">James A. Dickinson</name><affiliation wicri:level="4"><nlm:affiliation>University of Calgary, Alberta.</nlm:affiliation><orgName type="university">Université de Calgary</orgName><country>Canada</country><placeName><settlement type="city">Calgary</settlement><region type="state">Alberta</region></placeName></affiliation></author><author><name sortKey="Gubbay, Jonathan B" sort="Gubbay, Jonathan B" uniqKey="Gubbay J" first="Jonathan B" last="Gubbay">Jonathan B. Gubbay</name><affiliation wicri:level="3"><nlm:affiliation>Public Health Ontario, Toronto.</nlm:affiliation><country>Canada</country><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName><wicri:orgArea>Public Health Ontario</wicri:orgArea></affiliation><affiliation wicri:level="2"><nlm:affiliation>University of Toronto, Ontario.</nlm:affiliation><country>Canada</country><placeName><region type="province">Ontario</region></placeName><wicri:cityArea>University of Toronto</wicri:cityArea></affiliation></author><author><name sortKey="Fonseca, Kevin" sort="Fonseca, Kevin" uniqKey="Fonseca K" first="Kevin" last="Fonseca">Kevin Fonseca</name><affiliation wicri:level="4"><nlm:affiliation>University of Calgary, Alberta.</nlm:affiliation><orgName type="university">Université de Calgary</orgName><country>Canada</country><placeName><settlement type="city">Calgary</settlement><region type="state">Alberta</region></placeName></affiliation><affiliation wicri:level="3"><nlm:affiliation>Alberta Provincial Laboratory, Calgary.</nlm:affiliation><country>Canada</country><placeName><settlement type="city">Calgary</settlement><region type="state">Alberta</region></placeName><wicri:orgArea>Alberta Provincial Laboratory</wicri:orgArea></affiliation></author><author><name sortKey="Drews, Steven J" sort="Drews, Steven J" uniqKey="Drews S" first="Steven J" last="Drews">Steven J. Drews</name><affiliation wicri:level="3"><nlm:affiliation>Alberta Provincial Laboratory, Edmonton.</nlm:affiliation><country>Canada</country><placeName><settlement type="city">Edmonton</settlement><region type="state">Alberta</region></placeName><wicri:orgArea>Alberta Provincial Laboratory</wicri:orgArea></affiliation><affiliation wicri:level="3"><nlm:affiliation>University of Alberta, Edmonton.</nlm:affiliation><country>Canada</country><placeName><settlement type="city">Edmonton</settlement><region type="state">Alberta</region></placeName><wicri:orgArea>University of Alberta</wicri:orgArea></affiliation></author><author><name sortKey="Charest, Hugues" sort="Charest, Hugues" uniqKey="Charest H" first="Hugues" last="Charest">Hugues Charest</name><affiliation><nlm:affiliation>Institut National de Santé Publique du Québec.</nlm:affiliation><wicri:noCountry code="no comma">Institut National de Santé Publique du Québec.</wicri:noCountry></affiliation></author><author><name sortKey="Martineau, Christine" sort="Martineau, Christine" uniqKey="Martineau C" first="Christine" last="Martineau">Christine Martineau</name><affiliation><nlm:affiliation>Institut National de Santé Publique du Québec.</nlm:affiliation><wicri:noCountry code="no comma">Institut National de Santé Publique du Québec.</wicri:noCountry></affiliation></author><author><name sortKey="Krajden, Mel" sort="Krajden, Mel" uniqKey="Krajden M" first="Mel" last="Krajden">Mel Krajden</name><affiliation><nlm:affiliation>British Columbia Centre for Disease Control.</nlm:affiliation><wicri:noCountry code="no comma">British Columbia Centre for Disease Control.</wicri:noCountry></affiliation><affiliation wicri:level="3"><nlm:affiliation>University of British Columbia, Vancouver.</nlm:affiliation><country>Canada</country><placeName><settlement type="city">Vancouver</settlement><region type="state">Colombie-Britannique</region></placeName><wicri:orgArea>University of British Columbia</wicri:orgArea></affiliation></author><author><name sortKey="Petric, Martin" sort="Petric, Martin" uniqKey="Petric M" first="Martin" last="Petric">Martin Petric</name><affiliation wicri:level="3"><nlm:affiliation>University of British Columbia, Vancouver.</nlm:affiliation><country>Canada</country><placeName><settlement type="city">Vancouver</settlement><region type="state">Colombie-Britannique</region></placeName><wicri:orgArea>University of British Columbia</wicri:orgArea></affiliation></author><author><name sortKey="Bastien, Nathalie" sort="Bastien, Nathalie" uniqKey="Bastien N" first="Nathalie" last="Bastien">Nathalie Bastien</name><affiliation wicri:level="1"><nlm:affiliation>National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Manitoba, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Manitoba</wicri:regionArea><wicri:noRegion>Manitoba</wicri:noRegion></affiliation></author><author><name sortKey="Li, Yan" sort="Li, Yan" uniqKey="Li Y" first="Yan" last="Li">Yan Li</name><affiliation wicri:level="1"><nlm:affiliation>National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Manitoba, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Manitoba</wicri:regionArea><wicri:noRegion>Manitoba</wicri:noRegion></affiliation></author></analytic><series><title level="j">The Journal of infectious diseases</title><idno type="eISSN">1537-6613</idno><imprint><date when="2017" type="published">2017</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adolescent (MeSH)</term><term>Adult (MeSH)</term><term>Age Factors (MeSH)</term><term>Aged (MeSH)</term><term>Aged, 80 and over (MeSH)</term><term>Canada (epidemiology)</term><term>Case-Control Studies (MeSH)</term><term>Child (MeSH)</term><term>Child, Preschool (MeSH)</term><term>Humans (MeSH)</term><term>Infant (MeSH)</term><term>Infant, Newborn (MeSH)</term><term>Influenza B virus (isolation & purification)</term><term>Influenza, Human (diagnosis)</term><term>Influenza, Human (epidemiology)</term><term>Middle Aged (MeSH)</term><term>Sentinel Surveillance (MeSH)</term><term>Young Adult (MeSH)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Adolescent (MeSH)</term><term>Adulte (MeSH)</term><term>Adulte d'âge moyen (MeSH)</term><term>Canada (épidémiologie)</term><term>Enfant (MeSH)</term><term>Enfant d'âge préscolaire (MeSH)</term><term>Facteurs âges (MeSH)</term><term>Grippe humaine (diagnostic)</term><term>Grippe humaine (épidémiologie)</term><term>Humains (MeSH)</term><term>Jeune adulte (MeSH)</term><term>Nourrisson (MeSH)</term><term>Nouveau-né (MeSH)</term><term>Sujet âgé (MeSH)</term><term>Sujet âgé de 80 ans ou plus (MeSH)</term><term>Surveillance sentinelle (MeSH)</term><term>Virus influenza B (isolement et purification)</term><term>Études cas-témoins (MeSH)</term></keywords><keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Influenza, Human</term></keywords><keywords scheme="MESH" qualifier="diagnostic" xml:lang="fr"><term>Grippe humaine</term></keywords><keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Canada</term><term>Influenza, Human</term></keywords><keywords scheme="MESH" qualifier="isolation & purification" xml:lang="en"><term>Influenza B virus</term></keywords><keywords scheme="MESH" qualifier="isolement et purification" xml:lang="fr"><term>Virus influenza B</term></keywords><keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr"><term>Canada</term><term>Grippe humaine</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adolescent</term><term>Adult</term><term>Age Factors</term><term>Aged</term><term>Aged, 80 and over</term><term>Case-Control Studies</term><term>Child</term><term>Child, Preschool</term><term>Humans</term><term>Infant</term><term>Infant, Newborn</term><term>Middle Aged</term><term>Sentinel Surveillance</term><term>Young Adult</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Adolescent</term><term>Adulte</term><term>Adulte d'âge moyen</term><term>Enfant</term><term>Enfant d'âge préscolaire</term><term>Facteurs âges</term><term>Humains</term><term>Jeune adulte</term><term>Nourrisson</term><term>Nouveau-né</term><term>Sujet âgé</term><term>Sujet âgé de 80 ans ou plus</term><term>Surveillance sentinelle</term><term>Études cas-témoins</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Age-related differences in influenza B lineage detection were explored in the community-based Canadian Sentinel Practitioner Surveillance Network (SPSN) from 2010-2011 to 2015-2016. Whereas >80% of B(Victoria) cases were <40 years old, B(Yamagata) cases showed a bimodal age distribution with 27% who were <20 years old and 61% who were 30-64 years old, but with a notable gap in cases between 20 and 29 years old (4%). Overall, the median age was 20 years lower for B(Victoria) vs B(Yamagata) cases (20 vs 40 years; P < .01). Additional phylodynamic and immuno-epidemiological research is needed to understand age-related variation in influenza B risk by lineage, with potential implications for prevention and control across the lifespan.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">28934439</PMID><DateCompleted><Year>2017</Year><Month>09</Month><Day>29</Day></DateCompleted><DateRevised><Year>2018</Year><Month>12</Month><Day>15</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Electronic">1537-6613</ISSN><JournalIssue CitedMedium="Internet"><Volume>216</Volume><Issue>6</Issue><PubDate><Year>2017</Year><Month>09</Month><Day>15</Day></PubDate></JournalIssue><Title>The Journal of infectious diseases</Title><ISOAbbreviation>J. Infect. Dis.</ISOAbbreviation></Journal><ArticleTitle>Age-Related Differences in Influenza B Infection by Lineage in a Community-Based Sentinel System, 2010-2011 to 2015-2016, Canada.</ArticleTitle><Pagination><MedlinePgn>697-702</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1093/infdis/jix393</ELocationID><Abstract><AbstractText>Age-related differences in influenza B lineage detection were explored in the community-based Canadian Sentinel Practitioner Surveillance Network (SPSN) from 2010-2011 to 2015-2016. Whereas >80% of B(Victoria) cases were <40 years old, B(Yamagata) cases showed a bimodal age distribution with 27% who were <20 years old and 61% who were 30-64 years old, but with a notable gap in cases between 20 and 29 years old (4%). Overall, the median age was 20 years lower for B(Victoria) vs B(Yamagata) cases (20 vs 40 years; P < .01). Additional phylodynamic and immuno-epidemiological research is needed to understand age-related variation in influenza B risk by lineage, with potential implications for prevention and control across the lifespan.</AbstractText><CopyrightInformation>© The Author 2017. Published by Oxford University Press for the Infectious Diseases Society of America.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Skowronski</LastName><ForeName>Danuta M</ForeName><Initials>DM</Initials><AffiliationInfo><Affiliation>British Columbia Centre for Disease Control.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>University of British Columbia, Vancouver.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Chambers</LastName><ForeName>Catharine</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>British Columbia Centre for Disease Control.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>De Serres</LastName><ForeName>Gaston</ForeName><Initials>G</Initials><AffiliationInfo><Affiliation>Institut National de Santé Publique du Québec.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Laval University.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Centre Hospitalier Universitaire de Québec, Québec City.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Sabaiduc</LastName><ForeName>Suzana</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>British Columbia Centre for Disease Control.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Winter</LastName><ForeName>Anne-Luise</ForeName><Initials>AL</Initials><AffiliationInfo><Affiliation>Public Health Ontario, Toronto.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Dickinson</LastName><ForeName>James A</ForeName><Initials>JA</Initials><AffiliationInfo><Affiliation>University of Calgary, Alberta.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Gubbay</LastName><ForeName>Jonathan B</ForeName><Initials>JB</Initials><AffiliationInfo><Affiliation>Public Health Ontario, Toronto.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>University of Toronto, Ontario.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Fonseca</LastName><ForeName>Kevin</ForeName><Initials>K</Initials><AffiliationInfo><Affiliation>University of Calgary, Alberta.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Alberta Provincial Laboratory, Calgary.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Drews</LastName><ForeName>Steven J</ForeName><Initials>SJ</Initials><AffiliationInfo><Affiliation>Alberta Provincial Laboratory, Edmonton.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>University of Alberta, Edmonton.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Charest</LastName><ForeName>Hugues</ForeName><Initials>H</Initials><AffiliationInfo><Affiliation>Institut National de Santé Publique du Québec.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Martineau</LastName><ForeName>Christine</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>Institut National de Santé Publique du Québec.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Krajden</LastName><ForeName>Mel</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>British Columbia Centre for Disease Control.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>University of British Columbia, Vancouver.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Petric</LastName><ForeName>Martin</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>University of British Columbia, Vancouver.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Bastien</LastName><ForeName>Nathalie</ForeName><Initials>N</Initials><AffiliationInfo><Affiliation>National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Manitoba, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Li</LastName><ForeName>Yan</ForeName><Initials>Y</Initials><AffiliationInfo><Affiliation>National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Manitoba, Canada.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><GrantList CompleteYN="Y"><Grant><GrantID>TPA-90193</GrantID><Agency>CIHR</Agency><Country>Canada</Country></Grant></GrantList><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType></PublicationTypeList></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>J Infect Dis</MedlineTA><NlmUniqueID>0413675</NlmUniqueID><ISSNLinking>0022-1899</ISSNLinking></MedlineJournalInfo><CitationSubset>AIM</CitationSubset><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000293" MajorTopicYN="N">Adolescent</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000328" MajorTopicYN="N">Adult</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000367" MajorTopicYN="Y">Age Factors</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000368" MajorTopicYN="N">Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000369" MajorTopicYN="N">Aged, 80 and over</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D002170" MajorTopicYN="N">Canada</DescriptorName><QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D016022" MajorTopicYN="N">Case-Control Studies</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D002648" MajorTopicYN="N">Child</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D002675" MajorTopicYN="N">Child, Preschool</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D007223" MajorTopicYN="N">Infant</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D007231" MajorTopicYN="N">Infant, Newborn</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D009981" MajorTopicYN="N">Influenza B virus</DescriptorName><QualifierName UI="Q000302" MajorTopicYN="Y">isolation & purification</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D007251" MajorTopicYN="N">Influenza, Human</DescriptorName><QualifierName UI="Q000175" MajorTopicYN="N">diagnosis</QualifierName><QualifierName UI="Q000453" MajorTopicYN="Y">epidemiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D018571" MajorTopicYN="Y">Sentinel Surveillance</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D055815" MajorTopicYN="N">Young Adult</DescriptorName></MeshHeading></MeshHeadingList><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="Y">age</Keyword><Keyword MajorTopicYN="Y">birth cohort effects</Keyword><Keyword MajorTopicYN="Y">influenza B lineage</Keyword><Keyword MajorTopicYN="Y">influenza B virus</Keyword><Keyword MajorTopicYN="Y">risk</Keyword></KeywordList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2017</Year><Month>06</Month><Day>20</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2017</Year><Month>08</Month><Day>03</Day></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2017</Year><Month>9</Month><Day>22</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2017</Year><Month>9</Month><Day>22</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate 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