Prevalence of influenza A virus in live-captured North Atlantic gray seals: a possible wild reservoir.
Identifieur interne : 000140 ( Main/Exploration ); précédent : 000139; suivant : 000141Prevalence of influenza A virus in live-captured North Atlantic gray seals: a possible wild reservoir.
Auteurs : Wendy Blay Puryear [États-Unis] ; Mandy Keogh [États-Unis] ; Nichola Hill [États-Unis] ; Jerry Moxley [États-Unis] ; Elizabeth Josephson [États-Unis] ; Kimberly Ryan Davis [États-Unis] ; Chistopher Bandoro [États-Unis] ; Damian Lidgard [Canada] ; Andrea Bogomolni [États-Unis] ; Milton Levin [États-Unis] ; Shelley Lang [Canada] ; Michael Hammill [Canada] ; Don Bowen [Canada] ; David W. Johnston [États-Unis] ; Tracy Romano [États-Unis] ; Gordon Waring [États-Unis] ; Jonathan Runstadler [États-Unis]Source :
- Emerging microbes & infections [ 2222-1751 ] ; 2016.
Descripteurs français
- KwdFr :
- ARN viral (sang), Animaux (MeSH), Animaux sauvages (virologie), Anticorps antiviraux (sang), Canada (épidémiologie), Grippe humaine (immunologie), Grippe humaine (transmission), Grippe humaine (virologie), Grippe humaine (épidémiologie), Humains (MeSH), Infections à Orthomyxoviridae (immunologie), Infections à Orthomyxoviridae (médecine vétérinaire), Infections à Orthomyxoviridae (virologie), Infections à Orthomyxoviridae (épidémiologie), Nouvelle-Écosse (épidémiologie), Phoques (virologie), Prévalence (MeSH), Réaction de polymérisation en chaîne (MeSH), Réservoirs de maladies (MeSH), Surveillance épidémiologique (MeSH), Télémétrie (MeSH), Virus de la grippe A (génétique), Virus de la grippe A (immunologie), Virus de la grippe A (isolement et purification), États-Unis (épidémiologie).
- MESH :
- génétique : Virus de la grippe A.
- immunologie : Grippe humaine, Infections à Orthomyxoviridae, Virus de la grippe A.
- isolement et purification : Virus de la grippe A.
- médecine vétérinaire : Infections à Orthomyxoviridae.
- sang : ARN viral, Anticorps antiviraux.
- virologie : Animaux sauvages, Grippe humaine, Infections à Orthomyxoviridae, Phoques.
- épidémiologie : Canada, Grippe humaine, Infections à Orthomyxoviridae, Nouvelle-Écosse, États-Unis.
- Animaux, Humains, Prévalence, Réaction de polymérisation en chaîne, Réservoirs de maladies, Surveillance épidémiologique, Télémétrie.
English descriptors
- KwdEn :
- Animals (MeSH), Animals, Wild (virology), Antibodies, Viral (blood), Canada (epidemiology), Disease Reservoirs (MeSH), Epidemiological Monitoring (MeSH), Humans (MeSH), Influenza A virus (genetics), Influenza A virus (immunology), Influenza A virus (isolation & purification), Influenza, Human (epidemiology), Influenza, Human (immunology), Influenza, Human (transmission), Influenza, Human (virology), Nova Scotia (epidemiology), Orthomyxoviridae Infections (epidemiology), Orthomyxoviridae Infections (immunology), Orthomyxoviridae Infections (veterinary), Orthomyxoviridae Infections (virology), Polymerase Chain Reaction (MeSH), Prevalence (MeSH), RNA, Viral (blood), Seals, Earless (virology), Telemetry (MeSH), United States (epidemiology).
- MESH :
- chemical , blood : Antibodies, Viral, RNA, Viral.
- epidemiology : Canada, Influenza, Human, Nova Scotia, Orthomyxoviridae Infections, United States.
- genetics : Influenza A virus.
- immunology : Influenza A virus, Influenza, Human, Orthomyxoviridae Infections.
- isolation & purification : Influenza A virus.
- transmission : Influenza, Human.
- veterinary : Orthomyxoviridae Infections.
- virology : Animals, Wild, Influenza, Human, Orthomyxoviridae Infections, Seals, Earless.
- Animals, Disease Reservoirs, Epidemiological Monitoring, Humans, Polymerase Chain Reaction, Prevalence, Telemetry.
Abstract
Influenza A virus (IAV) has been associated with multiple unusual mortality events (UMEs) in North Atlantic pinnipeds, frequently attributed to spillover of virus from wild-bird reservoirs. To determine if endemic infection persists outside of UMEs, we undertook a multiyear investigation of IAV in healthy, live-captured Northwest Atlantic gray seals (Halichoerus grypus). From 2013 to 2015, we sampled 345 pups and 57 adults from Cape Cod, MA, USA and Nova Scotia, Canada consistently detecting IAV infection across all groups. There was an overall viral prevalence of 9.0% (95% confidence interval (CI): 6.4%-12.5%) in weaned pups and 5.3% (CI: 1.2%-14.6%) in adults, with seroprevalences of 19.3% (CI: 15.0%-24.5%) and 50% (CI: 33.7%-66.4%), respectively. Positive sera showed a broad reactivity to diverse influenza subtypes. IAV status did not correlate with measures of animal health nor impact animal movement or foraging. This study demonstrated that Northwest Atlantic gray seals are both permissive to and tolerant of diverse IAV, possibly representing an endemically infected wild reservoir population.
DOI: 10.1038/emi.2016.77
PubMed: 27485496
PubMed Central: PMC5034098
Affiliations:
Links toward previous steps (curation, corpus...)
Le document en format XML
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Technology, Cambridge, MA 02139</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Keogh, Mandy" sort="Keogh, Mandy" uniqKey="Keogh M" first="Mandy" last="Keogh">Mandy Keogh</name><affiliation wicri:level="2"><nlm:affiliation>Mystic Aquarium, Mystic, CT 06355, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Mystic Aquarium, Mystic, CT 06355</wicri:regionArea><placeName><region type="state">Connecticut</region></placeName></affiliation></author><author><name sortKey="Hill, Nichola" sort="Hill, Nichola" uniqKey="Hill N" first="Nichola" last="Hill">Nichola Hill</name><affiliation wicri:level="2"><nlm:affiliation>Massachusetts Institute of Technology, Cambridge, MA 02139, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Massachusetts Institute of Technology, Cambridge, MA 02139</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Moxley, Jerry" sort="Moxley, Jerry" uniqKey="Moxley J" first="Jerry" last="Moxley">Jerry Moxley</name><affiliation wicri:level="2"><nlm:affiliation>Duke University, Beaufort, NC 28516, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Duke University, Beaufort, NC 28516</wicri:regionArea><placeName><region type="state">Caroline du Nord</region></placeName></affiliation></author><author><name sortKey="Josephson, Elizabeth" sort="Josephson, Elizabeth" uniqKey="Josephson E" first="Elizabeth" last="Josephson">Elizabeth Josephson</name><affiliation wicri:level="2"><nlm:affiliation>National Oceanic and Atmospheric Administration, Northeast Fisheries Science Center, Woods Hole, MA 02543, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>National Oceanic and Atmospheric Administration, Northeast Fisheries Science Center, Woods Hole, MA 02543</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Davis, Kimberly Ryan" sort="Davis, Kimberly Ryan" uniqKey="Davis K" first="Kimberly Ryan" last="Davis">Kimberly Ryan Davis</name><affiliation wicri:level="2"><nlm:affiliation>Massachusetts Institute of Technology, Cambridge, MA 02139, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Massachusetts Institute of Technology, Cambridge, MA 02139</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Bandoro, Chistopher" sort="Bandoro, Chistopher" uniqKey="Bandoro C" first="Chistopher" last="Bandoro">Chistopher Bandoro</name><affiliation wicri:level="2"><nlm:affiliation>Massachusetts Institute of Technology, Cambridge, MA 02139, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Massachusetts Institute of Technology, Cambridge, MA 02139</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Lidgard, Damian" sort="Lidgard, Damian" uniqKey="Lidgard D" first="Damian" last="Lidgard">Damian Lidgard</name><affiliation wicri:level="1"><nlm:affiliation>Dalhousie University, Halifax, Nova Scotia, Canada B3H 1C2.</nlm:affiliation><country>Canada</country><wicri:regionArea>Dalhousie University, Halifax, Nova Scotia</wicri:regionArea><wicri:noRegion>Nova Scotia</wicri:noRegion></affiliation></author><author><name sortKey="Bogomolni, Andrea" sort="Bogomolni, Andrea" uniqKey="Bogomolni A" first="Andrea" last="Bogomolni">Andrea Bogomolni</name><affiliation wicri:level="2"><nlm:affiliation>Woods Hole Oceanographic Institution, Woods Hole, MA 02543, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Woods Hole Oceanographic Institution, Woods Hole, MA 02543</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Levin, Milton" sort="Levin, Milton" uniqKey="Levin M" first="Milton" last="Levin">Milton Levin</name><affiliation wicri:level="2"><nlm:affiliation>University of Connecticut, Storrs, CT 06268, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>University of Connecticut, Storrs, CT 06268</wicri:regionArea><placeName><region type="state">Connecticut</region></placeName></affiliation></author><author><name sortKey="Lang, Shelley" sort="Lang, Shelley" uniqKey="Lang S" first="Shelley" last="Lang">Shelley Lang</name><affiliation wicri:level="1"><nlm:affiliation>Department of Fisheries and Oceans, Dartmouth, Nova Scotia, Canada B2Y 4A2.</nlm:affiliation><country>Canada</country><wicri:regionArea>Department of Fisheries and Oceans, Dartmouth, Nova Scotia</wicri:regionArea><wicri:noRegion>Nova Scotia</wicri:noRegion></affiliation></author><author><name sortKey="Hammill, Michael" sort="Hammill, Michael" uniqKey="Hammill M" first="Michael" last="Hammill">Michael Hammill</name><affiliation wicri:level="1"><nlm:affiliation>Department of Fisheries and Oceans, Dartmouth, Nova Scotia, Canada B2Y 4A2.</nlm:affiliation><country>Canada</country><wicri:regionArea>Department of Fisheries and Oceans, Dartmouth, Nova Scotia</wicri:regionArea><wicri:noRegion>Nova Scotia</wicri:noRegion></affiliation></author><author><name sortKey="Bowen, Don" sort="Bowen, Don" uniqKey="Bowen D" first="Don" last="Bowen">Don Bowen</name><affiliation wicri:level="1"><nlm:affiliation>Department of Fisheries and Oceans, Dartmouth, Nova Scotia, Canada B2Y 4A2.</nlm:affiliation><country>Canada</country><wicri:regionArea>Department of Fisheries and Oceans, Dartmouth, Nova Scotia</wicri:regionArea><wicri:noRegion>Nova Scotia</wicri:noRegion></affiliation></author><author><name sortKey="Johnston, David W" sort="Johnston, David W" uniqKey="Johnston D" first="David W" last="Johnston">David W. Johnston</name><affiliation wicri:level="2"><nlm:affiliation>Duke University, Beaufort, NC 28516, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Duke University, Beaufort, NC 28516</wicri:regionArea><placeName><region type="state">Caroline du Nord</region></placeName></affiliation></author><author><name sortKey="Romano, Tracy" sort="Romano, Tracy" uniqKey="Romano T" first="Tracy" last="Romano">Tracy Romano</name><affiliation wicri:level="2"><nlm:affiliation>Mystic Aquarium, Mystic, CT 06355, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Mystic Aquarium, Mystic, CT 06355</wicri:regionArea><placeName><region type="state">Connecticut</region></placeName></affiliation></author><author><name sortKey="Waring, Gordon" sort="Waring, Gordon" uniqKey="Waring G" first="Gordon" last="Waring">Gordon Waring</name><affiliation wicri:level="2"><nlm:affiliation>National Oceanic and Atmospheric Administration, Northeast Fisheries Science Center, Woods Hole, MA 02543, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>National Oceanic and Atmospheric Administration, Northeast Fisheries Science Center, Woods Hole, MA 02543</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Runstadler, Jonathan" sort="Runstadler, Jonathan" uniqKey="Runstadler J" first="Jonathan" last="Runstadler">Jonathan Runstadler</name><affiliation wicri:level="2"><nlm:affiliation>Massachusetts Institute of Technology, Cambridge, MA 02139, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Massachusetts Institute of Technology, Cambridge, MA 02139</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author></analytic><series><title level="j">Emerging microbes & infections</title><idno type="eISSN">2222-1751</idno><imprint><date when="2016" type="published">2016</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Animals (MeSH)</term><term>Animals, Wild (virology)</term><term>Antibodies, Viral (blood)</term><term>Canada (epidemiology)</term><term>Disease Reservoirs (MeSH)</term><term>Epidemiological Monitoring (MeSH)</term><term>Humans (MeSH)</term><term>Influenza A virus (genetics)</term><term>Influenza A virus (immunology)</term><term>Influenza A virus (isolation & purification)</term><term>Influenza, Human (epidemiology)</term><term>Influenza, Human (immunology)</term><term>Influenza, Human (transmission)</term><term>Influenza, Human (virology)</term><term>Nova Scotia (epidemiology)</term><term>Orthomyxoviridae Infections (epidemiology)</term><term>Orthomyxoviridae Infections (immunology)</term><term>Orthomyxoviridae Infections (veterinary)</term><term>Orthomyxoviridae Infections (virology)</term><term>Polymerase Chain Reaction (MeSH)</term><term>Prevalence (MeSH)</term><term>RNA, Viral (blood)</term><term>Seals, Earless (virology)</term><term>Telemetry (MeSH)</term><term>United States (epidemiology)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>ARN viral (sang)</term><term>Animaux (MeSH)</term><term>Animaux sauvages (virologie)</term><term>Anticorps antiviraux (sang)</term><term>Canada (épidémiologie)</term><term>Grippe humaine (immunologie)</term><term>Grippe humaine (transmission)</term><term>Grippe humaine (virologie)</term><term>Grippe humaine (épidémiologie)</term><term>Humains (MeSH)</term><term>Infections à Orthomyxoviridae (immunologie)</term><term>Infections à Orthomyxoviridae (médecine vétérinaire)</term><term>Infections à Orthomyxoviridae (virologie)</term><term>Infections à Orthomyxoviridae (épidémiologie)</term><term>Nouvelle-Écosse (épidémiologie)</term><term>Phoques (virologie)</term><term>Prévalence (MeSH)</term><term>Réaction de polymérisation en chaîne (MeSH)</term><term>Réservoirs de maladies (MeSH)</term><term>Surveillance épidémiologique (MeSH)</term><term>Télémétrie (MeSH)</term><term>Virus de la grippe A (génétique)</term><term>Virus de la grippe A (immunologie)</term><term>Virus de la grippe A (isolement et purification)</term><term>États-Unis (épidémiologie)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="blood" xml:lang="en"><term>Antibodies, Viral</term><term>RNA, Viral</term></keywords><keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Canada</term><term>Influenza, Human</term><term>Nova Scotia</term><term>Orthomyxoviridae Infections</term><term>United States</term></keywords><keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Influenza A virus</term></keywords><keywords scheme="MESH" qualifier="génétique" xml:lang="fr"><term>Virus de la grippe A</term></keywords><keywords scheme="MESH" qualifier="immunologie" xml:lang="fr"><term>Grippe humaine</term><term>Infections à Orthomyxoviridae</term><term>Virus de la grippe A</term></keywords><keywords scheme="MESH" qualifier="immunology" xml:lang="en"><term>Influenza A virus</term><term>Influenza, Human</term><term>Orthomyxoviridae Infections</term></keywords><keywords scheme="MESH" qualifier="isolation & purification" xml:lang="en"><term>Influenza A virus</term></keywords><keywords scheme="MESH" qualifier="isolement et purification" xml:lang="fr"><term>Virus de la grippe A</term></keywords><keywords scheme="MESH" qualifier="médecine vétérinaire" xml:lang="fr"><term>Infections à Orthomyxoviridae</term></keywords><keywords scheme="MESH" qualifier="sang" xml:lang="fr"><term>ARN viral</term><term>Anticorps antiviraux</term></keywords><keywords scheme="MESH" qualifier="transmission" xml:lang="en"><term>Influenza, Human</term></keywords><keywords scheme="MESH" qualifier="veterinary" xml:lang="en"><term>Orthomyxoviridae Infections</term></keywords><keywords scheme="MESH" qualifier="virologie" xml:lang="fr"><term>Animaux sauvages</term><term>Grippe humaine</term><term>Infections à Orthomyxoviridae</term><term>Phoques</term></keywords><keywords scheme="MESH" qualifier="virology" xml:lang="en"><term>Animals, Wild</term><term>Influenza, Human</term><term>Orthomyxoviridae Infections</term><term>Seals, Earless</term></keywords><keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr"><term>Canada</term><term>Grippe humaine</term><term>Infections à Orthomyxoviridae</term><term>Nouvelle-Écosse</term><term>États-Unis</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Animals</term><term>Disease Reservoirs</term><term>Epidemiological Monitoring</term><term>Humans</term><term>Polymerase Chain Reaction</term><term>Prevalence</term><term>Telemetry</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Animaux</term><term>Humains</term><term>Prévalence</term><term>Réaction de polymérisation en chaîne</term><term>Réservoirs de maladies</term><term>Surveillance épidémiologique</term><term>Télémétrie</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Influenza A virus (IAV) has been associated with multiple unusual mortality events (UMEs) in North Atlantic pinnipeds, frequently attributed to spillover of virus from wild-bird reservoirs. To determine if endemic infection persists outside of UMEs, we undertook a multiyear investigation of IAV in healthy, live-captured Northwest Atlantic gray seals (Halichoerus grypus). From 2013 to 2015, we sampled 345 pups and 57 adults from Cape Cod, MA, USA and Nova Scotia, Canada consistently detecting IAV infection across all groups. There was an overall viral prevalence of 9.0% (95% confidence interval (CI): 6.4%-12.5%) in weaned pups and 5.3% (CI: 1.2%-14.6%) in adults, with seroprevalences of 19.3% (CI: 15.0%-24.5%) and 50% (CI: 33.7%-66.4%), respectively. Positive sera showed a broad reactivity to diverse influenza subtypes. IAV status did not correlate with measures of animal health nor impact animal movement or foraging. This study demonstrated that Northwest Atlantic gray seals are both permissive to and tolerant of diverse IAV, possibly representing an endemically infected wild reservoir population. </div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">27485496</PMID><DateCompleted><Year>2017</Year><Month>01</Month><Day>24</Day></DateCompleted><DateRevised><Year>2018</Year><Month>11</Month><Day>13</Day></DateRevised><Article PubModel="Electronic"><Journal><ISSN IssnType="Electronic">2222-1751</ISSN><JournalIssue CitedMedium="Internet"><Volume>5</Volume><Issue>8</Issue><PubDate><Year>2016</Year><Month>Aug</Month><Day>03</Day></PubDate></JournalIssue><Title>Emerging microbes & infections</Title><ISOAbbreviation>Emerg Microbes Infect</ISOAbbreviation></Journal><ArticleTitle>Prevalence of influenza A virus in live-captured North Atlantic gray seals: a possible wild reservoir.</ArticleTitle><Pagination><MedlinePgn>e81</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1038/emi.2016.77</ELocationID><Abstract><AbstractText>Influenza A virus (IAV) has been associated with multiple unusual mortality events (UMEs) in North Atlantic pinnipeds, frequently attributed to spillover of virus from wild-bird reservoirs. To determine if endemic infection persists outside of UMEs, we undertook a multiyear investigation of IAV in healthy, live-captured Northwest Atlantic gray seals (Halichoerus grypus). From 2013 to 2015, we sampled 345 pups and 57 adults from Cape Cod, MA, USA and Nova Scotia, Canada consistently detecting IAV infection across all groups. There was an overall viral prevalence of 9.0% (95% confidence interval (CI): 6.4%-12.5%) in weaned pups and 5.3% (CI: 1.2%-14.6%) in adults, with seroprevalences of 19.3% (CI: 15.0%-24.5%) and 50% (CI: 33.7%-66.4%), respectively. Positive sera showed a broad reactivity to diverse influenza subtypes. IAV status did not correlate with measures of animal health nor impact animal movement or foraging. This study demonstrated that Northwest Atlantic gray seals are both permissive to and tolerant of diverse IAV, possibly representing an endemically infected wild reservoir population. </AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Puryear</LastName><ForeName>Wendy Blay</ForeName><Initials>WB</Initials><AffiliationInfo><Affiliation>Massachusetts Institute of Technology, Cambridge, MA 02139, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Keogh</LastName><ForeName>Mandy</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Mystic Aquarium, Mystic, CT 06355, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hill</LastName><ForeName>Nichola</ForeName><Initials>N</Initials><AffiliationInfo><Affiliation>Massachusetts Institute of Technology, Cambridge, MA 02139, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Moxley</LastName><ForeName>Jerry</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Duke University, Beaufort, NC 28516, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Josephson</LastName><ForeName>Elizabeth</ForeName><Initials>E</Initials><AffiliationInfo><Affiliation>National Oceanic and Atmospheric Administration, Northeast Fisheries Science Center, Woods Hole, MA 02543, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Davis</LastName><ForeName>Kimberly Ryan</ForeName><Initials>KR</Initials><AffiliationInfo><Affiliation>Massachusetts Institute of Technology, Cambridge, MA 02139, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Bandoro</LastName><ForeName>Chistopher</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>Massachusetts Institute of Technology, Cambridge, MA 02139, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lidgard</LastName><ForeName>Damian</ForeName><Initials>D</Initials><AffiliationInfo><Affiliation>Dalhousie University, Halifax, Nova Scotia, Canada B3H 1C2.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Bogomolni</LastName><ForeName>Andrea</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Woods Hole Oceanographic Institution, Woods Hole, MA 02543, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Levin</LastName><ForeName>Milton</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>University of Connecticut, Storrs, CT 06268, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lang</LastName><ForeName>Shelley</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Department of Fisheries and Oceans, Dartmouth, Nova Scotia, Canada B2Y 4A2.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hammill</LastName><ForeName>Michael</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Department of Fisheries and Oceans, Dartmouth, Nova Scotia, Canada B2Y 4A2.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Bowen</LastName><ForeName>Don</ForeName><Initials>D</Initials><AffiliationInfo><Affiliation>Department of Fisheries and Oceans, Dartmouth, Nova Scotia, Canada B2Y 4A2.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Johnston</LastName><ForeName>David W</ForeName><Initials>DW</Initials><AffiliationInfo><Affiliation>Duke University, Beaufort, NC 28516, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Romano</LastName><ForeName>Tracy</ForeName><Initials>T</Initials><AffiliationInfo><Affiliation>Mystic Aquarium, Mystic, CT 06355, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Waring</LastName><ForeName>Gordon</ForeName><Initials>G</Initials><AffiliationInfo><Affiliation>National Oceanic and Atmospheric Administration, Northeast Fisheries Science Center, Woods Hole, MA 02543, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Runstadler</LastName><ForeName>Jonathan</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Massachusetts Institute of Technology, Cambridge, MA 02139, USA.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><GrantList CompleteYN="Y"><Grant><GrantID>HHSN272201400008C</GrantID><Acronym>AI</Acronym><Agency>NIAID NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>T32 ES007020</GrantID><Acronym>ES</Acronym><Agency>NIEHS NIH HHS</Agency><Country>United States</Country></Grant></GrantList><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2016</Year><Month>08</Month><Day>03</Day></ArticleDate></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>Emerg Microbes Infect</MedlineTA><NlmUniqueID>101594885</NlmUniqueID><ISSNLinking>2222-1751</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D000914">Antibodies, Viral</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D012367">RNA, Viral</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000818" MajorTopicYN="N">Animals</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000835" MajorTopicYN="N">Animals, Wild</DescriptorName><QualifierName UI="Q000821" MajorTopicYN="Y">virology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D000914" MajorTopicYN="N">Antibodies, Viral</DescriptorName><QualifierName UI="Q000097" MajorTopicYN="N">blood</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D002170" MajorTopicYN="N">Canada</DescriptorName><QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D004197" MajorTopicYN="Y">Disease Reservoirs</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D062665" MajorTopicYN="N">Epidemiological Monitoring</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D009980" MajorTopicYN="N">Influenza A virus</DescriptorName><QualifierName UI="Q000235" MajorTopicYN="Y">genetics</QualifierName><QualifierName UI="Q000276" MajorTopicYN="N">immunology</QualifierName><QualifierName UI="Q000302" MajorTopicYN="N">isolation & purification</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D007251" MajorTopicYN="N">Influenza, Human</DescriptorName><QualifierName UI="Q000453" MajorTopicYN="Y">epidemiology</QualifierName><QualifierName UI="Q000276" MajorTopicYN="N">immunology</QualifierName><QualifierName UI="Q000635" MajorTopicYN="N">transmission</QualifierName><QualifierName UI="Q000821" MajorTopicYN="N">virology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D009674" MajorTopicYN="N">Nova Scotia</DescriptorName><QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D009976" MajorTopicYN="N">Orthomyxoviridae Infections</DescriptorName><QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName><QualifierName UI="Q000276" MajorTopicYN="N">immunology</QualifierName><QualifierName UI="Q000662" MajorTopicYN="Y">veterinary</QualifierName><QualifierName UI="Q000821" MajorTopicYN="N">virology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D016133" MajorTopicYN="N">Polymerase Chain Reaction</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D015995" MajorTopicYN="N">Prevalence</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D012367" MajorTopicYN="N">RNA, Viral</DescriptorName><QualifierName UI="Q000097" MajorTopicYN="N">blood</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D046048" MajorTopicYN="N">Seals, Earless</DescriptorName><QualifierName UI="Q000821" MajorTopicYN="Y">virology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D013686" MajorTopicYN="N">Telemetry</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D014481" MajorTopicYN="N">United States</DescriptorName><QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2016</Year><Month>02</Month><Day>01</Day></PubMedPubDate><PubMedPubDate PubStatus="revised"><Year>2016</Year><Month>04</Month><Day>25</Day></PubMedPubDate><PubMedPubDate 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sort="Puryear, Wendy Blay" uniqKey="Puryear W" first="Wendy Blay" last="Puryear">Wendy Blay Puryear</name></region><name sortKey="Bandoro, Chistopher" sort="Bandoro, Chistopher" uniqKey="Bandoro C" first="Chistopher" last="Bandoro">Chistopher Bandoro</name><name sortKey="Bogomolni, Andrea" sort="Bogomolni, Andrea" uniqKey="Bogomolni A" first="Andrea" last="Bogomolni">Andrea Bogomolni</name><name sortKey="Davis, Kimberly Ryan" sort="Davis, Kimberly Ryan" uniqKey="Davis K" first="Kimberly Ryan" last="Davis">Kimberly Ryan Davis</name><name sortKey="Hill, Nichola" sort="Hill, Nichola" uniqKey="Hill N" first="Nichola" last="Hill">Nichola Hill</name><name sortKey="Johnston, David W" sort="Johnston, David W" uniqKey="Johnston D" first="David W" last="Johnston">David W. Johnston</name><name sortKey="Josephson, Elizabeth" sort="Josephson, Elizabeth" uniqKey="Josephson E" first="Elizabeth" last="Josephson">Elizabeth Josephson</name><name sortKey="Keogh, Mandy" sort="Keogh, Mandy" uniqKey="Keogh M" first="Mandy" last="Keogh">Mandy Keogh</name><name sortKey="Levin, Milton" sort="Levin, Milton" uniqKey="Levin M" first="Milton" last="Levin">Milton Levin</name><name sortKey="Moxley, Jerry" sort="Moxley, Jerry" uniqKey="Moxley J" first="Jerry" last="Moxley">Jerry Moxley</name><name sortKey="Romano, Tracy" sort="Romano, Tracy" uniqKey="Romano T" first="Tracy" last="Romano">Tracy Romano</name><name sortKey="Runstadler, Jonathan" sort="Runstadler, Jonathan" uniqKey="Runstadler J" first="Jonathan" last="Runstadler">Jonathan Runstadler</name><name sortKey="Waring, Gordon" sort="Waring, Gordon" uniqKey="Waring G" first="Gordon" last="Waring">Gordon Waring</name></country><country name="Canada"><noRegion><name sortKey="Lidgard, Damian" sort="Lidgard, Damian" uniqKey="Lidgard D" first="Damian" last="Lidgard">Damian Lidgard</name></noRegion><name sortKey="Bowen, Don" sort="Bowen, Don" uniqKey="Bowen D" first="Don" last="Bowen">Don Bowen</name><name sortKey="Hammill, Michael" sort="Hammill, Michael" uniqKey="Hammill M" first="Michael" last="Hammill">Michael Hammill</name><name sortKey="Lang, Shelley" sort="Lang, Shelley" uniqKey="Lang S" first="Shelley" last="Lang">Shelley Lang</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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