GrippeCanadaV4, Main, Exploration, bibRecordById, pubmed:26259704

Highly Pathogenic Avian Influenza A(H5N1) Virus Struck Migratory Birds in China in 2015.

Identifieur interne : 000220 ( Main/Exploration ); précédent : 000219; suivant : 000221

Highly Pathogenic Avian Influenza A(H5N1) Virus Struck Migratory Birds in China in 2015.

Source :

Scientific reports [ 2045-2322 ] ; 2015.

RBID : pubmed:26259704

Descripteurs français

KwdFr :
- Animaux (MeSH), Animaux sauvages (MeSH), Canada (MeSH), Canards (virologie), Chine (MeSH), Glycoprotéine hémagglutinine du virus influenza (génétique), Grippe chez les oiseaux (génétique), Grippe chez les oiseaux (virologie), Grippe chez les oiseaux (épidémiologie), Grippe humaine (génétique), Grippe humaine (virologie), Grippe humaine (épidémiologie), Humains (MeSH), Migration animale (MeSH), Phylogenèse (MeSH), Protéines virales (génétique), RNA replicase (génétique), Sous-type H5N1 du virus de la grippe A (génétique), Sous-type H5N1 du virus de la grippe A (pathogénicité), Sous-type H9N2 du virus de la grippe A (génétique), Sous-type H9N2 du virus de la grippe A (pathogénicité), Virus de la grippe A (génétique), Virus de la grippe A (pathogénicité), Épidémies de maladies (MeSH).
MESH :
- génétique : Glycoprotéine hémagglutinine du virus influenza, Grippe chez les oiseaux, Grippe humaine, Protéines virales, RNA replicase, Sous-type H5N1 du virus de la grippe A, Sous-type H9N2 du virus de la grippe A, Virus de la grippe A.
- pathogénicité : Sous-type H5N1 du virus de la grippe A, Sous-type H9N2 du virus de la grippe A, Virus de la grippe A.
- virologie : Canards, Grippe chez les oiseaux, Grippe humaine.
- épidémiologie : Grippe chez les oiseaux, Grippe humaine.
- Animaux, Animaux sauvages, Canada, Chine, Humains, Migration animale, Phylogenèse, Épidémies de maladies.
Wicri :
- geographic : Canada, République populaire de Chine.

English descriptors

KwdEn :
- Animal Migration (MeSH), Animals (MeSH), Animals, Wild (MeSH), Canada (MeSH), China (MeSH), Disease Outbreaks (MeSH), Ducks (virology), Hemagglutinin Glycoproteins, Influenza Virus (genetics), Humans (MeSH), Influenza A Virus, H5N1 Subtype (genetics), Influenza A Virus, H5N1 Subtype (pathogenicity), Influenza A Virus, H9N2 Subtype (genetics), Influenza A Virus, H9N2 Subtype (pathogenicity), Influenza A virus (genetics), Influenza A virus (pathogenicity), Influenza in Birds (epidemiology), Influenza in Birds (genetics), Influenza in Birds (virology), Influenza, Human (epidemiology), Influenza, Human (genetics), Influenza, Human (virology), Phylogeny (MeSH), RNA Replicase (genetics), Viral Proteins (genetics).
MESH :
- chemical , genetics : Hemagglutinin Glycoproteins, Influenza Virus, RNA Replicase, Viral Proteins.
- geographic : Canada, China.
- epidemiology : Influenza in Birds, Influenza, Human.
- genetics : Influenza A Virus, H5N1 Subtype, Influenza A Virus, H9N2 Subtype, Influenza A virus, Influenza in Birds, Influenza, Human.
- pathogenicity : Influenza A Virus, H5N1 Subtype, Influenza A Virus, H9N2 Subtype, Influenza A virus.
- virology : Ducks, Influenza in Birds, Influenza, Human.
- Animal Migration, Animals, Animals, Wild, Disease Outbreaks, Humans, Phylogeny.

Abstract

Approximately 100 migratory birds, including whooper swans and pochards, were found dead in the Sanmenxia Reservoir Area of China during January 2015. The causative agent behind this outbreak was identified as H5N1 highly pathogenic avian influenza virus (HPAIV). Genetic and phylogenetic analyses revealed that this Sanmenxia H5N1 virus was a novel reassortant, possessing a Clade 2.3.2.1c HA gene and a H9N2-derived PB2 gene. Sanmenxia Clade 2.3.2.1c-like H5N1 viruses possess the closest genetic identity to A/Alberta/01/2014 (H5N1), which recently caused a fatal respiratory infection in Canada with signs of meningoencephalitis, a highly unusual symptom with influenza infections in humans. Furthermore, this virus was shown to be highly pathogenic to both birds and mammals, and demonstrate tropism for the nervous system. Due to the geographical location of Sanmenxia, these novel H5N1 viruses also have the potential to be imported to other regions through the migration of wild birds, similar to the H5N1 outbreak amongst migratory birds in Qinghai Lake during 2005. Therefore, further investigation and monitoring is required to prevent this novel reassortant virus from becoming a new threat to public health.

DOI: 10.1038/srep12986
PubMed: 26259704
PubMed Central: PMC4531313

Affiliations:

Links toward previous steps (curation, corpus...)

to stream Main, to step Corpus: 000198
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Le document en format XML

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<sourceDesc><biblStruct><analytic><title xml:lang="en">Highly Pathogenic Avian Influenza A(H5N1) Virus Struck Migratory Birds in China in 2015.</title>
<author><name sortKey="Bi, Yuhai" sort="Bi, Yuhai" uniqKey="Bi Y" first="Yuhai" last="Bi">Yuhai Bi</name>
<affiliation wicri:level="1"><nlm:affiliation>1] CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China [2] Shenzhen Key Laboratory of Pathogen and Immunity, Shenzhen Third People's Hospital, Shenzhen 518112, China [3] Center for Influenza Research and Early-warning (CASCIRE), Chinese Academy of Sciences, Beijing 100101, China.</nlm:affiliation>
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<wicri:regionArea>1] CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China [2] Shenzhen Key Laboratory of Pathogen and Immunity, Shenzhen Third People's Hospital, Shenzhen 518112, China [3] Center for Influenza Research and Early-warning (CASCIRE), Chinese Academy of Sciences, Beijing 100101</wicri:regionArea>
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<author><name sortKey="Zhang, Zhenjie" sort="Zhang, Zhenjie" uniqKey="Zhang Z" first="Zhenjie" last="Zhang">Zhenjie Zhang</name>
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<author><name sortKey="Liu, Wenjun" sort="Liu, Wenjun" uniqKey="Liu W" first="Wenjun" last="Liu">Wenjun Liu</name>
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<author><name sortKey="Yin, Yanbo" sort="Yin, Yanbo" uniqKey="Yin Y" first="Yanbo" last="Yin">Yanbo Yin</name>
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<author><name sortKey="Hong, Jianmin" sort="Hong, Jianmin" uniqKey="Hong J" first="Jianmin" last="Hong">Jianmin Hong</name>
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<author><name sortKey="Li, Xiangdong" sort="Li, Xiangdong" uniqKey="Li X" first="Xiangdong" last="Li">Xiangdong Li</name>
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<author><name sortKey="Wang, Haiming" sort="Wang, Haiming" uniqKey="Wang H" first="Haiming" last="Wang">Haiming Wang</name>
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<author><name sortKey="Wong, Gary" sort="Wong, Gary" uniqKey="Wong G" first="Gary" last="Wong">Gary Wong</name>
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</placeName>
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<author><name sortKey="Chen, Jianjun" sort="Chen, Jianjun" uniqKey="Chen J" first="Jianjun" last="Chen">Jianjun Chen</name>
<affiliation wicri:level="1"><nlm:affiliation>1] Center for Influenza Research and Early-warning (CASCIRE), Chinese Academy of Sciences, Beijing 100101, China [2] CAS Key Laboratory of Special Pathogens and Biosafety, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan 430071, China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>1] Center for Influenza Research and Early-warning (CASCIRE), Chinese Academy of Sciences, Beijing 100101, China [2] CAS Key Laboratory of Special Pathogens and Biosafety, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan 430071</wicri:regionArea>
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<author><name sortKey="Li, Yunfeng" sort="Li, Yunfeng" uniqKey="Li Y" first="Yunfeng" last="Li">Yunfeng Li</name>
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<country xml:lang="fr">République populaire de Chine</country>
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<wicri:noRegion>Sanmenxia 472000</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Ru, Wendong" sort="Ru, Wendong" uniqKey="Ru W" first="Wendong" last="Ru">Wendong Ru</name>
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<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>National Urban Wetland Park of Sanmenxia Swan Lake, Sanmenxia 472000</wicri:regionArea>
<wicri:noRegion>Sanmenxia 472000</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Gao, Ruyi" sort="Gao, Ruyi" uniqKey="Gao R" first="Ruyi" last="Gao">Ruyi Gao</name>
<affiliation wicri:level="1"><nlm:affiliation>National Urban Wetland Park of Sanmenxia Swan Lake, Sanmenxia 472000, China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>National Urban Wetland Park of Sanmenxia Swan Lake, Sanmenxia 472000</wicri:regionArea>
<wicri:noRegion>Sanmenxia 472000</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Liu, Di" sort="Liu, Di" uniqKey="Liu D" first="Di" last="Liu">Di Liu</name>
<affiliation wicri:level="1"><nlm:affiliation>1] CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China [2] Center for Influenza Research and Early-warning (CASCIRE), Chinese Academy of Sciences, Beijing 100101, China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>1] CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China [2] Center for Influenza Research and Early-warning (CASCIRE), Chinese Academy of Sciences, Beijing 100101</wicri:regionArea>
<placeName><settlement type="city">Pékin</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Liu, Yingxia" sort="Liu, Yingxia" uniqKey="Liu Y" first="Yingxia" last="Liu">Yingxia Liu</name>
<affiliation wicri:level="1"><nlm:affiliation>Shenzhen Key Laboratory of Pathogen and Immunity, Shenzhen Third People's Hospital, Shenzhen 518112, China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Shenzhen Key Laboratory of Pathogen and Immunity, Shenzhen Third People's Hospital, Shenzhen 518112</wicri:regionArea>
<placeName><settlement type="city">Shenzhen</settlement>
<region type="province">Guangdong</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Zhou, Boping" sort="Zhou, Boping" uniqKey="Zhou B" first="Boping" last="Zhou">Boping Zhou</name>
<affiliation wicri:level="1"><nlm:affiliation>Shenzhen Key Laboratory of Pathogen and Immunity, Shenzhen Third People's Hospital, Shenzhen 518112, China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Shenzhen Key Laboratory of Pathogen and Immunity, Shenzhen Third People's Hospital, Shenzhen 518112</wicri:regionArea>
<placeName><settlement type="city">Shenzhen</settlement>
<region type="province">Guangdong</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Gao, George F" sort="Gao, George F" uniqKey="Gao G" first="George F" last="Gao">George F. Gao</name>
<affiliation wicri:level="4"><nlm:affiliation>1] CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China [2] Shenzhen Key Laboratory of Pathogen and Immunity, Shenzhen Third People's Hospital, Shenzhen 518112, China [3] Center for Influenza Research and Early-warning (CASCIRE), Chinese Academy of Sciences, Beijing 100101, China [4] Collaborative Innovation Center for Diagnosis and Treatment of Infectious disease, Zhejiang University, Hanzhou 310003, China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>1] CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China [2] Shenzhen Key Laboratory of Pathogen and Immunity, Shenzhen Third People's Hospital, Shenzhen 518112, China [3] Center for Influenza Research and Early-warning (CASCIRE), Chinese Academy of Sciences, Beijing 100101, China [4] Collaborative Innovation Center for Diagnosis and Treatment of Infectious disease, Zhejiang University, Hanzhou 310003</wicri:regionArea>
<orgName type="university">Université de Zhejiang</orgName>
<placeName><settlement type="city">Hangzhou</settlement>
<region type="province">Zhejiang</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Shi, Weifeng" sort="Shi, Weifeng" uniqKey="Shi W" first="Weifeng" last="Shi">Weifeng Shi</name>
<affiliation wicri:level="1"><nlm:affiliation>Institute of Pathogen Biology, Taishan Medical College, Taian 271016, China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Institute of Pathogen Biology, Taishan Medical College, Taian 271016</wicri:regionArea>
<wicri:noRegion>Taian 271016</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Lei, Fumin" sort="Lei, Fumin" uniqKey="Lei F" first="Fumin" last="Lei">Fumin Lei</name>
<affiliation wicri:level="1"><nlm:affiliation>1] CAS Key Laboratory of Zoological Systematics and Evolution, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China [2] Center for Influenza Research and Early-warning (CASCIRE), Chinese Academy of Sciences, Beijing 100101, China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>1] CAS Key Laboratory of Zoological Systematics and Evolution, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China [2] Center for Influenza Research and Early-warning (CASCIRE), Chinese Academy of Sciences, Beijing 100101</wicri:regionArea>
<placeName><settlement type="city">Pékin</settlement>
</placeName>
</affiliation>
</author>
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<series><title level="j">Scientific reports</title>
<idno type="eISSN">2045-2322</idno>
<imprint><date when="2015" type="published">2015</date>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Animal Migration (MeSH)</term>
<term>Animals (MeSH)</term>
<term>Animals, Wild (MeSH)</term>
<term>Canada (MeSH)</term>
<term>China (MeSH)</term>
<term>Disease Outbreaks (MeSH)</term>
<term>Ducks (virology)</term>
<term>Hemagglutinin Glycoproteins, Influenza Virus (genetics)</term>
<term>Humans (MeSH)</term>
<term>Influenza A Virus, H5N1 Subtype (genetics)</term>
<term>Influenza A Virus, H5N1 Subtype (pathogenicity)</term>
<term>Influenza A Virus, H9N2 Subtype (genetics)</term>
<term>Influenza A Virus, H9N2 Subtype (pathogenicity)</term>
<term>Influenza A virus (genetics)</term>
<term>Influenza A virus (pathogenicity)</term>
<term>Influenza in Birds (epidemiology)</term>
<term>Influenza in Birds (genetics)</term>
<term>Influenza in Birds (virology)</term>
<term>Influenza, Human (epidemiology)</term>
<term>Influenza, Human (genetics)</term>
<term>Influenza, Human (virology)</term>
<term>Phylogeny (MeSH)</term>
<term>RNA Replicase (genetics)</term>
<term>Viral Proteins (genetics)</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Animaux (MeSH)</term>
<term>Animaux sauvages (MeSH)</term>
<term>Canada (MeSH)</term>
<term>Canards (virologie)</term>
<term>Chine (MeSH)</term>
<term>Glycoprotéine hémagglutinine du virus influenza (génétique)</term>
<term>Grippe chez les oiseaux (génétique)</term>
<term>Grippe chez les oiseaux (virologie)</term>
<term>Grippe chez les oiseaux (épidémiologie)</term>
<term>Grippe humaine (génétique)</term>
<term>Grippe humaine (virologie)</term>
<term>Grippe humaine (épidémiologie)</term>
<term>Humains (MeSH)</term>
<term>Migration animale (MeSH)</term>
<term>Phylogenèse (MeSH)</term>
<term>Protéines virales (génétique)</term>
<term>RNA replicase (génétique)</term>
<term>Sous-type H5N1 du virus de la grippe A (génétique)</term>
<term>Sous-type H5N1 du virus de la grippe A (pathogénicité)</term>
<term>Sous-type H9N2 du virus de la grippe A (génétique)</term>
<term>Sous-type H9N2 du virus de la grippe A (pathogénicité)</term>
<term>Virus de la grippe A (génétique)</term>
<term>Virus de la grippe A (pathogénicité)</term>
<term>Épidémies de maladies (MeSH)</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="genetics" xml:lang="en"><term>Hemagglutinin Glycoproteins, Influenza Virus</term>
<term>RNA Replicase</term>
<term>Viral Proteins</term>
</keywords>
<keywords scheme="MESH" type="geographic" xml:lang="en"><term>Canada</term>
<term>China</term>
</keywords>
<keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Influenza in Birds</term>
<term>Influenza, Human</term>
</keywords>
<keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Influenza A Virus, H5N1 Subtype</term>
<term>Influenza A Virus, H9N2 Subtype</term>
<term>Influenza A virus</term>
<term>Influenza in Birds</term>
<term>Influenza, Human</term>
</keywords>
<keywords scheme="MESH" qualifier="génétique" xml:lang="fr"><term>Glycoprotéine hémagglutinine du virus influenza</term>
<term>Grippe chez les oiseaux</term>
<term>Grippe humaine</term>
<term>Protéines virales</term>
<term>RNA replicase</term>
<term>Sous-type H5N1 du virus de la grippe A</term>
<term>Sous-type H9N2 du virus de la grippe A</term>
<term>Virus de la grippe A</term>
</keywords>
<keywords scheme="MESH" qualifier="pathogenicity" xml:lang="en"><term>Influenza A Virus, H5N1 Subtype</term>
<term>Influenza A Virus, H9N2 Subtype</term>
<term>Influenza A virus</term>
</keywords>
<keywords scheme="MESH" qualifier="pathogénicité" xml:lang="fr"><term>Sous-type H5N1 du virus de la grippe A</term>
<term>Sous-type H9N2 du virus de la grippe A</term>
<term>Virus de la grippe A</term>
</keywords>
<keywords scheme="MESH" qualifier="virologie" xml:lang="fr"><term>Canards</term>
<term>Grippe chez les oiseaux</term>
<term>Grippe humaine</term>
</keywords>
<keywords scheme="MESH" qualifier="virology" xml:lang="en"><term>Ducks</term>
<term>Influenza in Birds</term>
<term>Influenza, Human</term>
</keywords>
<keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr"><term>Grippe chez les oiseaux</term>
<term>Grippe humaine</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Animal Migration</term>
<term>Animals</term>
<term>Animals, Wild</term>
<term>Disease Outbreaks</term>
<term>Humans</term>
<term>Phylogeny</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>Animaux</term>
<term>Animaux sauvages</term>
<term>Canada</term>
<term>Chine</term>
<term>Humains</term>
<term>Migration animale</term>
<term>Phylogenèse</term>
<term>Épidémies de maladies</term>
</keywords>
<keywords scheme="Wicri" type="geographic" xml:lang="fr"><term>Canada</term>
<term>République populaire de Chine</term>
</keywords>
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<front><div type="abstract" xml:lang="en">Approximately 100 migratory birds, including whooper swans and pochards, were found dead in the Sanmenxia Reservoir Area of China during January 2015. The causative agent behind this outbreak was identified as H5N1 highly pathogenic avian influenza virus (HPAIV). Genetic and phylogenetic analyses revealed that this Sanmenxia H5N1 virus was a novel reassortant, possessing a Clade 2.3.2.1c HA gene and a H9N2-derived PB2 gene. Sanmenxia Clade 2.3.2.1c-like H5N1 viruses possess the closest genetic identity to A/Alberta/01/2014 (H5N1), which recently caused a fatal respiratory infection in Canada with signs of meningoencephalitis, a highly unusual symptom with influenza infections in humans. Furthermore, this virus was shown to be highly pathogenic to both birds and mammals, and demonstrate tropism for the nervous system. Due to the geographical location of Sanmenxia, these novel H5N1 viruses also have the potential to be imported to other regions through the migration of wild birds, similar to the H5N1 outbreak amongst migratory birds in Qinghai Lake during 2005. Therefore, further investigation and monitoring is required to prevent this novel reassortant virus from becoming a new threat to public health. </div>
</front>
</TEI>
<pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">26259704</PMID>
<DateCompleted><Year>2016</Year>
<Month>08</Month>
<Day>01</Day>
</DateCompleted>
<DateRevised><Year>2018</Year>
<Month>11</Month>
<Day>13</Day>
</DateRevised>
<Article PubModel="Electronic"><Journal><ISSN IssnType="Electronic">2045-2322</ISSN>
<JournalIssue CitedMedium="Internet"><Volume>5</Volume>
<PubDate><Year>2015</Year>
<Month>Aug</Month>
<Day>11</Day>
</PubDate>
</JournalIssue>
<Title>Scientific reports</Title>
<ISOAbbreviation>Sci Rep</ISOAbbreviation>
</Journal>
<ArticleTitle>Highly Pathogenic Avian Influenza A(H5N1) Virus Struck Migratory Birds in China in 2015.</ArticleTitle>
<Pagination><MedlinePgn>12986</MedlinePgn>
</Pagination>
<ELocationID EIdType="doi" ValidYN="Y">10.1038/srep12986</ELocationID>
<Abstract><AbstractText>Approximately 100 migratory birds, including whooper swans and pochards, were found dead in the Sanmenxia Reservoir Area of China during January 2015. The causative agent behind this outbreak was identified as H5N1 highly pathogenic avian influenza virus (HPAIV). Genetic and phylogenetic analyses revealed that this Sanmenxia H5N1 virus was a novel reassortant, possessing a Clade 2.3.2.1c HA gene and a H9N2-derived PB2 gene. Sanmenxia Clade 2.3.2.1c-like H5N1 viruses possess the closest genetic identity to A/Alberta/01/2014 (H5N1), which recently caused a fatal respiratory infection in Canada with signs of meningoencephalitis, a highly unusual symptom with influenza infections in humans. Furthermore, this virus was shown to be highly pathogenic to both birds and mammals, and demonstrate tropism for the nervous system. Due to the geographical location of Sanmenxia, these novel H5N1 viruses also have the potential to be imported to other regions through the migration of wild birds, similar to the H5N1 outbreak amongst migratory birds in Qinghai Lake during 2005. Therefore, further investigation and monitoring is required to prevent this novel reassortant virus from becoming a new threat to public health. </AbstractText>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Bi</LastName>
<ForeName>Yuhai</ForeName>
<Initials>Y</Initials>
<AffiliationInfo><Affiliation>1] CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China [2] Shenzhen Key Laboratory of Pathogen and Immunity, Shenzhen Third People's Hospital, Shenzhen 518112, China [3] Center for Influenza Research and Early-warning (CASCIRE), Chinese Academy of Sciences, Beijing 100101, China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Zhang</LastName>
<ForeName>Zhenjie</ForeName>
<Initials>Z</Initials>
<AffiliationInfo><Affiliation>Institute of Pathogen Biology, Taishan Medical College, Taian 271016, China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Liu</LastName>
<ForeName>Wenjun</ForeName>
<Initials>W</Initials>
<AffiliationInfo><Affiliation>1] CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China [2] Center for Influenza Research and Early-warning (CASCIRE), Chinese Academy of Sciences, Beijing 100101, China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Yin</LastName>
<ForeName>Yanbo</ForeName>
<Initials>Y</Initials>
<AffiliationInfo><Affiliation>College of Animal Science and Veterinary Medicine, Qingdao Agricultural University, Qingdao 266109, China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Hong</LastName>
<ForeName>Jianmin</ForeName>
<Initials>J</Initials>
<AffiliationInfo><Affiliation>Beijing Key Laboratory of Plant Genetic Resources and Low-carbon Environmental Biotechnology, Capital Normal University, Beijing 100048, China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Li</LastName>
<ForeName>Xiangdong</ForeName>
<Initials>X</Initials>
<AffiliationInfo><Affiliation>State Key Laboratory for Agrobiotechnology, China Agricultural University, Beijing 100193, China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Wang</LastName>
<ForeName>Haiming</ForeName>
<Initials>H</Initials>
<AffiliationInfo><Affiliation>College of Animal Science and Veterinary Medicine, Shandong Agricultural University, Taian 271018, China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Wong</LastName>
<ForeName>Gary</ForeName>
<Initials>G</Initials>
<AffiliationInfo><Affiliation>CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Chen</LastName>
<ForeName>Jianjun</ForeName>
<Initials>J</Initials>
<AffiliationInfo><Affiliation>1] Center for Influenza Research and Early-warning (CASCIRE), Chinese Academy of Sciences, Beijing 100101, China [2] CAS Key Laboratory of Special Pathogens and Biosafety, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan 430071, China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Li</LastName>
<ForeName>Yunfeng</ForeName>
<Initials>Y</Initials>
<AffiliationInfo><Affiliation>National Urban Wetland Park of Sanmenxia Swan Lake, Sanmenxia 472000, China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Ru</LastName>
<ForeName>Wendong</ForeName>
<Initials>W</Initials>
<AffiliationInfo><Affiliation>National Urban Wetland Park of Sanmenxia Swan Lake, Sanmenxia 472000, China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Gao</LastName>
<ForeName>Ruyi</ForeName>
<Initials>R</Initials>
<AffiliationInfo><Affiliation>National Urban Wetland Park of Sanmenxia Swan Lake, Sanmenxia 472000, China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Liu</LastName>
<ForeName>Di</ForeName>
<Initials>D</Initials>
<AffiliationInfo><Affiliation>1] CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China [2] Center for Influenza Research and Early-warning (CASCIRE), Chinese Academy of Sciences, Beijing 100101, China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Liu</LastName>
<ForeName>Yingxia</ForeName>
<Initials>Y</Initials>
<AffiliationInfo><Affiliation>Shenzhen Key Laboratory of Pathogen and Immunity, Shenzhen Third People's Hospital, Shenzhen 518112, China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Zhou</LastName>
<ForeName>Boping</ForeName>
<Initials>B</Initials>
<AffiliationInfo><Affiliation>Shenzhen Key Laboratory of Pathogen and Immunity, Shenzhen Third People's Hospital, Shenzhen 518112, China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Gao</LastName>
<ForeName>George F</ForeName>
<Initials>GF</Initials>
<AffiliationInfo><Affiliation>1] CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China [2] Shenzhen Key Laboratory of Pathogen and Immunity, Shenzhen Third People's Hospital, Shenzhen 518112, China [3] Center for Influenza Research and Early-warning (CASCIRE), Chinese Academy of Sciences, Beijing 100101, China [4] Collaborative Innovation Center for Diagnosis and Treatment of Infectious disease, Zhejiang University, Hanzhou 310003, China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Shi</LastName>
<ForeName>Weifeng</ForeName>
<Initials>W</Initials>
<AffiliationInfo><Affiliation>Institute of Pathogen Biology, Taishan Medical College, Taian 271016, China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Lei</LastName>
<ForeName>Fumin</ForeName>
<Initials>F</Initials>
<AffiliationInfo><Affiliation>1] CAS Key Laboratory of Zoological Systematics and Evolution, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China [2] Center for Influenza Research and Early-warning (CASCIRE), Chinese Academy of Sciences, Beijing 100101, China.</Affiliation>
</AffiliationInfo>
</Author>
</AuthorList>
<Language>eng</Language>
<PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType>
<PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType>
</PublicationTypeList>
<ArticleDate DateType="Electronic"><Year>2015</Year>
<Month>08</Month>
<Day>11</Day>
</ArticleDate>
</Article>
<MedlineJournalInfo><Country>England</Country>
<MedlineTA>Sci Rep</MedlineTA>
<NlmUniqueID>101563288</NlmUniqueID>
<ISSNLinking>2045-2322</ISSNLinking>
</MedlineJournalInfo>
<ChemicalList><Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="D019267">Hemagglutinin Glycoproteins, Influenza Virus</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="C057027">PB2 protein, Influenzavirus A</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="D014764">Viral Proteins</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>EC 2.7.7.48</RegistryNumber>
<NameOfSubstance UI="D012324">RNA Replicase</NameOfSubstance>
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</ChemicalList>
<CitationSubset>IM</CitationSubset>
<MeshHeadingList><MeshHeading><DescriptorName UI="D025041" MajorTopicYN="N">Animal Migration</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D000818" MajorTopicYN="N">Animals</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D000835" MajorTopicYN="N">Animals, Wild</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D002170" MajorTopicYN="N" Type="Geographic">Canada</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D002681" MajorTopicYN="N" Type="Geographic">China</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D004196" MajorTopicYN="N">Disease Outbreaks</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D004372" MajorTopicYN="N">Ducks</DescriptorName>
<QualifierName UI="Q000821" MajorTopicYN="N">virology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D019267" MajorTopicYN="N">Hemagglutinin Glycoproteins, Influenza Virus</DescriptorName>
<QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D053124" MajorTopicYN="N">Influenza A Virus, H5N1 Subtype</DescriptorName>
<QualifierName UI="Q000235" MajorTopicYN="Y">genetics</QualifierName>
<QualifierName UI="Q000472" MajorTopicYN="N">pathogenicity</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D053127" MajorTopicYN="N">Influenza A Virus, H9N2 Subtype</DescriptorName>
<QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName>
<QualifierName UI="Q000472" MajorTopicYN="N">pathogenicity</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D009980" MajorTopicYN="N">Influenza A virus</DescriptorName>
<QualifierName UI="Q000235" MajorTopicYN="Y">genetics</QualifierName>
<QualifierName UI="Q000472" MajorTopicYN="N">pathogenicity</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D005585" MajorTopicYN="N">Influenza in Birds</DescriptorName>
<QualifierName UI="Q000453" MajorTopicYN="Y">epidemiology</QualifierName>
<QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName>
<QualifierName UI="Q000821" MajorTopicYN="N">virology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D007251" MajorTopicYN="N">Influenza, Human</DescriptorName>
<QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName>
<QualifierName UI="Q000235" MajorTopicYN="Y">genetics</QualifierName>
<QualifierName UI="Q000821" MajorTopicYN="N">virology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D010802" MajorTopicYN="N">Phylogeny</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D012324" MajorTopicYN="N">RNA Replicase</DescriptorName>
<QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D014764" MajorTopicYN="N">Viral Proteins</DescriptorName>
<QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName>
</MeshHeading>
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<PubmedData><History><PubMedPubDate PubStatus="received"><Year>2015</Year>
<Month>05</Month>
<Day>30</Day>
</PubMedPubDate>
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Highly Pathogenic Avian Influenza A(H5N1) Virus Struck Migratory Birds in China in 2015.

Highly Pathogenic Avian Influenza A(H5N1) Virus Struck Migratory Birds in China in 2015.

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