Seasonal influenza vaccine effectiveness in pre- and full-term children aged 6-23 months over multiple seasons.
Identifieur interne : 000342 ( Main/Exploration ); précédent : 000341; suivant : 000343Seasonal influenza vaccine effectiveness in pre- and full-term children aged 6-23 months over multiple seasons.
Auteurs : Shixin Shen [Canada] ; Michael A. Campitelli ; Andrew Calzavara ; Astrid Guttmann ; Jeffrey C. KwongSource :
- Vaccine [ 1873-2518 ] ; 2013.
Descripteurs français
- KwdFr :
- Femelle (MeSH), Grippe humaine (immunologie), Grippe humaine (prévention et contrôle), Grippe humaine (épidémiologie), Humains (MeSH), Mâle (MeSH), Nourrisson (MeSH), Nouveau-né (MeSH), Ontario (épidémiologie), Prématuré (MeSH), Saisons (MeSH), Soins ambulatoires (statistiques et données numériques), Vaccination (MeSH), Vaccins antigrippaux (administration et posologie), Vaccins antigrippaux (immunologie), Études de cohortes (MeSH).
- MESH :
- administration et posologie : Vaccins antigrippaux.
- immunologie : Grippe humaine, Vaccins antigrippaux.
- prévention et contrôle : Grippe humaine.
- statistiques et données numériques : Soins ambulatoires.
- épidémiologie : Grippe humaine, Ontario.
- Femelle, Humains, Mâle, Nourrisson, Nouveau-né, Prématuré, Saisons, Vaccination, Études de cohortes.
English descriptors
- KwdEn :
- Ambulatory Care (statistics & numerical data), Cohort Studies (MeSH), Female (MeSH), Humans (MeSH), Infant (MeSH), Infant, Newborn (MeSH), Infant, Premature (MeSH), Influenza Vaccines (administration & dosage), Influenza Vaccines (immunology), Influenza, Human (epidemiology), Influenza, Human (immunology), Influenza, Human (prevention & control), Male (MeSH), Ontario (epidemiology), Seasons (MeSH), Vaccination (MeSH).
- MESH :
- chemical , administration & dosage : Influenza Vaccines.
- chemical , immunology : Influenza Vaccines.
- epidemiology : Influenza, Human, Ontario.
- immunology : Influenza, Human.
- prevention & control : Influenza, Human.
- statistics & numerical data : Ambulatory Care.
- Cohort Studies, Female, Humans, Infant, Infant, Newborn, Infant, Premature, Male, Seasons, Vaccination.
Abstract
INTRODUCTION
This study aimed to determine the effectiveness of seasonal influenza vaccine in pre- and full-term children aged 6-23 months.
METHODS
We examined a cohort of 683,354 young children (7.7% preterm) over five influenza seasons (2004-2005 to 2008-2009) in Ontario, Canada. Vaccine effectiveness was estimated using influenza-coded ambulatory visits during virologically-confirmed influenza season periods as the outcome and multivariable Cox proportional hazards modeling.
RESULTS
Full vaccination was associated with a 19% reduction in influenza-coded ambulatory visits (HR=0.81; 95% CI, 0.68-0.97) in all children, and an 18% reduction in full-term children (HR=0.82; 95% CI, 0.68-0.99). We did not find significant vaccine effectiveness for preterm children. No benefit was found for partial vaccination.
CONCLUSIONS
In children younger than two years, only full influenza vaccination is associated with reduced influenza-coded ambulatory visits. Since the effectiveness of influenza vaccination in preterm children remains uncertain, further study of this highly vulnerable population is warranted.
DOI: 10.1016/j.vaccine.2013.05.011
PubMed: 23688524
Affiliations:
Links toward previous steps (curation, corpus...)
Le document en format XML
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Campitelli</name></author><author><name sortKey="Calzavara, Andrew" sort="Calzavara, Andrew" uniqKey="Calzavara A" first="Andrew" last="Calzavara">Andrew Calzavara</name></author><author><name sortKey="Guttmann, Astrid" sort="Guttmann, Astrid" uniqKey="Guttmann A" first="Astrid" last="Guttmann">Astrid Guttmann</name></author><author><name sortKey="Kwong, Jeffrey C" sort="Kwong, Jeffrey C" uniqKey="Kwong J" first="Jeffrey C" last="Kwong">Jeffrey C. 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Campitelli</name></author><author><name sortKey="Calzavara, Andrew" sort="Calzavara, Andrew" uniqKey="Calzavara A" first="Andrew" last="Calzavara">Andrew Calzavara</name></author><author><name sortKey="Guttmann, Astrid" sort="Guttmann, Astrid" uniqKey="Guttmann A" first="Astrid" last="Guttmann">Astrid Guttmann</name></author><author><name sortKey="Kwong, Jeffrey C" sort="Kwong, Jeffrey C" uniqKey="Kwong J" first="Jeffrey C" last="Kwong">Jeffrey C. Kwong</name></author></analytic><series><title level="j">Vaccine</title><idno type="eISSN">1873-2518</idno><imprint><date when="2013" type="published">2013</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Ambulatory Care (statistics & numerical data)</term><term>Cohort Studies (MeSH)</term><term>Female (MeSH)</term><term>Humans (MeSH)</term><term>Infant (MeSH)</term><term>Infant, Newborn (MeSH)</term><term>Infant, Premature (MeSH)</term><term>Influenza Vaccines (administration & dosage)</term><term>Influenza Vaccines (immunology)</term><term>Influenza, Human (epidemiology)</term><term>Influenza, Human (immunology)</term><term>Influenza, Human (prevention & control)</term><term>Male (MeSH)</term><term>Ontario (epidemiology)</term><term>Seasons (MeSH)</term><term>Vaccination (MeSH)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Femelle (MeSH)</term><term>Grippe humaine (immunologie)</term><term>Grippe humaine (prévention et contrôle)</term><term>Grippe humaine (épidémiologie)</term><term>Humains (MeSH)</term><term>Mâle (MeSH)</term><term>Nourrisson (MeSH)</term><term>Nouveau-né (MeSH)</term><term>Ontario (épidémiologie)</term><term>Prématuré (MeSH)</term><term>Saisons (MeSH)</term><term>Soins ambulatoires (statistiques et données numériques)</term><term>Vaccination (MeSH)</term><term>Vaccins antigrippaux (administration et posologie)</term><term>Vaccins antigrippaux (immunologie)</term><term>Études de cohortes (MeSH)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="administration & dosage" xml:lang="en"><term>Influenza Vaccines</term></keywords><keywords scheme="MESH" type="chemical" qualifier="immunology" xml:lang="en"><term>Influenza Vaccines</term></keywords><keywords scheme="MESH" qualifier="administration et posologie" xml:lang="fr"><term>Vaccins antigrippaux</term></keywords><keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Influenza, Human</term><term>Ontario</term></keywords><keywords scheme="MESH" qualifier="immunologie" xml:lang="fr"><term>Grippe humaine</term><term>Vaccins antigrippaux</term></keywords><keywords scheme="MESH" qualifier="immunology" xml:lang="en"><term>Influenza, Human</term></keywords><keywords scheme="MESH" qualifier="prevention & control" xml:lang="en"><term>Influenza, Human</term></keywords><keywords scheme="MESH" qualifier="prévention et contrôle" xml:lang="fr"><term>Grippe humaine</term></keywords><keywords scheme="MESH" qualifier="statistics & numerical data" xml:lang="en"><term>Ambulatory Care</term></keywords><keywords scheme="MESH" qualifier="statistiques et données numériques" xml:lang="fr"><term>Soins ambulatoires</term></keywords><keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr"><term>Grippe humaine</term><term>Ontario</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Cohort Studies</term><term>Female</term><term>Humans</term><term>Infant</term><term>Infant, Newborn</term><term>Infant, Premature</term><term>Male</term><term>Seasons</term><term>Vaccination</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Femelle</term><term>Humains</term><term>Mâle</term><term>Nourrisson</term><term>Nouveau-né</term><term>Prématuré</term><term>Saisons</term><term>Vaccination</term><term>Études de cohortes</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p><b>INTRODUCTION</b></p><p>This study aimed to determine the effectiveness of seasonal influenza vaccine in pre- and full-term children aged 6-23 months.</p></div><div type="abstract" xml:lang="en"><p><b>METHODS</b></p><p>We examined a cohort of 683,354 young children (7.7% preterm) over five influenza seasons (2004-2005 to 2008-2009) in Ontario, Canada. Vaccine effectiveness was estimated using influenza-coded ambulatory visits during virologically-confirmed influenza season periods as the outcome and multivariable Cox proportional hazards modeling.</p></div><div type="abstract" xml:lang="en"><p><b>RESULTS</b></p><p>Full vaccination was associated with a 19% reduction in influenza-coded ambulatory visits (HR=0.81; 95% CI, 0.68-0.97) in all children, and an 18% reduction in full-term children (HR=0.82; 95% CI, 0.68-0.99). We did not find significant vaccine effectiveness for preterm children. No benefit was found for partial vaccination.</p></div><div type="abstract" xml:lang="en"><p><b>CONCLUSIONS</b></p><p>In children younger than two years, only full influenza vaccination is associated with reduced influenza-coded ambulatory visits. Since the effectiveness of influenza vaccination in preterm children remains uncertain, further study of this highly vulnerable population is warranted.</p></div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" IndexingMethod="Curated" Owner="NLM"><PMID Version="1">23688524</PMID><DateCompleted><Year>2014</Year><Month>02</Month><Day>04</Day></DateCompleted><DateRevised><Year>2019</Year><Month>03</Month><Day>18</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1873-2518</ISSN><JournalIssue CitedMedium="Internet"><Volume>31</Volume><Issue>29</Issue><PubDate><Year>2013</Year><Month>Jun</Month><Day>24</Day></PubDate></JournalIssue><Title>Vaccine</Title><ISOAbbreviation>Vaccine</ISOAbbreviation></Journal><ArticleTitle>Seasonal influenza vaccine effectiveness in pre- and full-term children aged 6-23 months over multiple seasons.</ArticleTitle><Pagination><MedlinePgn>2974-8</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1016/j.vaccine.2013.05.011</ELocationID><ELocationID EIdType="pii" ValidYN="Y">S0264-410X(13)00589-6</ELocationID><Abstract><AbstractText Label="INTRODUCTION" NlmCategory="BACKGROUND">This study aimed to determine the effectiveness of seasonal influenza vaccine in pre- and full-term children aged 6-23 months.</AbstractText><AbstractText Label="METHODS" NlmCategory="METHODS">We examined a cohort of 683,354 young children (7.7% preterm) over five influenza seasons (2004-2005 to 2008-2009) in Ontario, Canada. Vaccine effectiveness was estimated using influenza-coded ambulatory visits during virologically-confirmed influenza season periods as the outcome and multivariable Cox proportional hazards modeling.</AbstractText><AbstractText Label="RESULTS" NlmCategory="RESULTS">Full vaccination was associated with a 19% reduction in influenza-coded ambulatory visits (HR=0.81; 95% CI, 0.68-0.97) in all children, and an 18% reduction in full-term children (HR=0.82; 95% CI, 0.68-0.99). We did not find significant vaccine effectiveness for preterm children. No benefit was found for partial vaccination.</AbstractText><AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">In children younger than two years, only full influenza vaccination is associated with reduced influenza-coded ambulatory visits. Since the effectiveness of influenza vaccination in preterm children remains uncertain, further study of this highly vulnerable population is warranted.</AbstractText><CopyrightInformation>Copyright © 2013 Elsevier Ltd. All rights reserved.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Shen</LastName><ForeName>Shixin</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Dalla Lana School of Public Health, University of Toronto, Toronto, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Campitelli</LastName><ForeName>Michael A</ForeName><Initials>MA</Initials></Author><Author ValidYN="Y"><LastName>Calzavara</LastName><ForeName>Andrew</ForeName><Initials>A</Initials></Author><Author ValidYN="Y"><LastName>Guttmann</LastName><ForeName>Astrid</ForeName><Initials>A</Initials></Author><Author ValidYN="Y"><LastName>Kwong</LastName><ForeName>Jeffrey C</ForeName><Initials>JC</Initials></Author></AuthorList><Language>eng</Language><GrantList CompleteYN="Y"><Grant><GrantID>82408</GrantID><Agency>Canadian Institutes of Health Research</Agency><Country>Canada</Country></Grant></GrantList><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2013</Year><Month>05</Month><Day>18</Day></ArticleDate></Article><MedlineJournalInfo><Country>Netherlands</Country><MedlineTA>Vaccine</MedlineTA><NlmUniqueID>8406899</NlmUniqueID><ISSNLinking>0264-410X</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D007252">Influenza Vaccines</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000553" MajorTopicYN="N">Ambulatory Care</DescriptorName><QualifierName UI="Q000706" MajorTopicYN="N">statistics & numerical data</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D015331" MajorTopicYN="N">Cohort Studies</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D007223" MajorTopicYN="N">Infant</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D007231" MajorTopicYN="N">Infant, Newborn</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D007234" MajorTopicYN="Y">Infant, Premature</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D007252" MajorTopicYN="N">Influenza Vaccines</DescriptorName><QualifierName UI="Q000008" MajorTopicYN="N">administration & dosage</QualifierName><QualifierName UI="Q000276" MajorTopicYN="Y">immunology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D007251" MajorTopicYN="N">Influenza, Human</DescriptorName><QualifierName UI="Q000453" MajorTopicYN="Y">epidemiology</QualifierName><QualifierName UI="Q000276" MajorTopicYN="N">immunology</QualifierName><QualifierName UI="Q000517" MajorTopicYN="Y">prevention & control</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D009864" MajorTopicYN="N">Ontario</DescriptorName><QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D012621" MajorTopicYN="N">Seasons</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D014611" MajorTopicYN="N">Vaccination</DescriptorName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2012</Year><Month>11</Month><Day>05</Day></PubMedPubDate><PubMedPubDate PubStatus="revised"><Year>2013</Year><Month>01</Month><Day>21</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2013</Year><Month>05</Month><Day>03</Day></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2013</Year><Month>5</Month><Day>22</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2013</Year><Month>5</Month><Day>22</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2014</Year><Month>2</Month><Day>5</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">23688524</ArticleId><ArticleId IdType="pii">S0264-410X(13)00589-6</ArticleId><ArticleId IdType="doi">10.1016/j.vaccine.2013.05.011</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>Canada</li></country><region><li>Ontario</li></region><settlement><li>Toronto</li></settlement><orgName><li>Université de Toronto</li></orgName></list><tree><noCountry><name sortKey="Calzavara, Andrew" sort="Calzavara, Andrew" uniqKey="Calzavara A" first="Andrew" last="Calzavara">Andrew Calzavara</name><name sortKey="Campitelli, Michael A" sort="Campitelli, Michael A" uniqKey="Campitelli M" first="Michael A" last="Campitelli">Michael A. Campitelli</name><name sortKey="Guttmann, Astrid" sort="Guttmann, Astrid" uniqKey="Guttmann A" first="Astrid" last="Guttmann">Astrid Guttmann</name><name sortKey="Kwong, Jeffrey C" sort="Kwong, Jeffrey C" uniqKey="Kwong J" first="Jeffrey C" last="Kwong">Jeffrey C. Kwong</name></noCountry><country name="Canada"><region name="Ontario"><name sortKey="Shen, Shixin" sort="Shen, Shixin" uniqKey="Shen S" first="Shixin" last="Shen">Shixin Shen</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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