Review of seasonal influenza in Canada: Burden of disease and the cost-effectiveness of quadrivalent inactivated influenza vaccines.
Identifieur interne : 000125 ( Main/Curation ); précédent : 000124; suivant : 000126Review of seasonal influenza in Canada: Burden of disease and the cost-effectiveness of quadrivalent inactivated influenza vaccines.
Auteurs : Edward W. Thommes [Canada] ; Morgan Kruse [États-Unis] ; Michele Kohli [Canada] ; Rohita Sharma [Canada] ; Stephen G. Noorduyn [Canada]Source :
- Human vaccines & immunotherapeutics [ 2164-554X ] ; 2017.
Descripteurs français
- KwdFr :
- Analyse coût-bénéfice (MeSH), Canada (épidémiologie), Coûts indirects de la maladie (MeSH), Grippe humaine (prévention et contrôle), Grippe humaine (économie), Grippe humaine (épidémiologie), Humains (MeSH), Modèles statistiques (MeSH), Vaccination (économie), Vaccins antigrippaux (administration et posologie), Vaccins antigrippaux (immunologie), Vaccins antigrippaux (économie), Vaccins inactivés (administration et posologie), Vaccins inactivés (immunologie), Vaccins inactivés (économie), Victoria (MeSH).
- MESH :
- administration et posologie : Vaccins antigrippaux, Vaccins inactivés.
- immunologie : Vaccins antigrippaux, Vaccins inactivés.
- prévention et contrôle : Grippe humaine.
- économie : Grippe humaine, Vaccination, Vaccins antigrippaux, Vaccins inactivés.
- épidémiologie : Canada, Grippe humaine.
- Analyse coût-bénéfice, Coûts indirects de la maladie, Humains, Modèles statistiques, Victoria.
English descriptors
- KwdEn :
- Canada (epidemiology), Cost of Illness (MeSH), Cost-Benefit Analysis (MeSH), Humans (MeSH), Influenza Vaccines (administration & dosage), Influenza Vaccines (economics), Influenza Vaccines (immunology), Influenza, Human (economics), Influenza, Human (epidemiology), Influenza, Human (prevention & control), Models, Statistical (MeSH), Vaccination (economics), Vaccines, Inactivated (administration & dosage), Vaccines, Inactivated (economics), Vaccines, Inactivated (immunology), Victoria (MeSH).
- MESH :
- chemical , administration & dosage : Influenza Vaccines, Vaccines, Inactivated.
- chemical , economics : Influenza Vaccines, Vaccines, Inactivated.
- economics : Influenza, Human, Vaccination.
- epidemiology : Canada, Influenza, Human.
- chemical , immunology : Influenza Vaccines, Vaccines, Inactivated.
- prevention & control : Influenza, Human.
- Cost of Illness, Cost-Benefit Analysis, Humans, Models, Statistical, Victoria.
Abstract
In the 2015/16 influenza season, the Canadian National Advisory Committee on Immunization (NACI) recommended vaccination with quadrivalent inactivated influenza vaccine (QIV) for infants aged 6-23 months and trivalent inactivated influenza vaccines (TIVs) or QIVs in adults. The objective of this review (GSK study identifier: HO-13-14054) is to examine the epidemiology and disease burden of influenza in Canada and the economic benefits of vaccination. To inform this review, we performed a systematic literature search of relevant Canadian literature and National surveillance data. Influenza B viruses from phylogenetically-distinct lineages (B/Yamagata and B/Victoria) co-circulate in Canada, and are an important cause of influenza complications. Modeling studies, including those postdating the search suggest that switching from TIV to QIV in Canada reduces the burden of influenza and would likely be cost-effective. However, more robust real-world outcomes data is required to inform health policy decision makers on appropriate influenza vaccination strategies for Canada.
DOI: 10.1080/21645515.2016.1251537
PubMed: 27858509
PubMed Central: PMC5404371
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pubmed:27858509Le document en format XML
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<front><div type="abstract" xml:lang="en">In the 2015/16 influenza season, the Canadian National Advisory Committee on Immunization (NACI) recommended vaccination with quadrivalent inactivated influenza vaccine (QIV) for infants aged 6-23 months and trivalent inactivated influenza vaccines (TIVs) or QIVs in adults. The objective of this review (GSK study identifier: HO-13-14054) is to examine the epidemiology and disease burden of influenza in Canada and the economic benefits of vaccination. To inform this review, we performed a systematic literature search of relevant Canadian literature and National surveillance data. Influenza B viruses from phylogenetically-distinct lineages (B/Yamagata and B/Victoria) co-circulate in Canada, and are an important cause of influenza complications. Modeling studies, including those postdating the search suggest that switching from TIV to QIV in Canada reduces the burden of influenza and would likely be cost-effective. However, more robust real-world outcomes data is required to inform health policy decision makers on appropriate influenza vaccination strategies for Canada.</div>
</front>
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<ForeName>Edward W</ForeName>
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<AffiliationInfo><Affiliation>a GSK, Health Economics and Outcomes Research , Mississauga , Ontario , Canada.</Affiliation>
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