GrippeBresilV2, Main, Exploration, bibRecord, 000051

Respiratory viruses among children with non-severe community-acquired pneumonia: A prospective cohort study.

Identifieur interne : 000051 ( Main/Exploration ); précédent : 000050; suivant : 000052

Respiratory viruses among children with non-severe community-acquired pneumonia: A prospective cohort study.

Auteurs : Amanda C. Nascimento-Carvalho [Brésil] ; Ana-Luisa Vilas-Boas [Brésil] ; Maria-Socorro H. Fontoura [Brésil] ; Tytti Vuorinen [Finlande] ; Cristiana M. Nascimento-Carvalho [Brésil]

Source :

Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology [ 1873-5967 ] ; 2018.

RBID : pubmed:29908521

Descripteurs français

KwdFr :
- Brésil (épidémiologie), Co-infection (virologie), Co-infection (épidémiologie), Coronavirus (génétique), Coronavirus (isolement et purification), Enfant d'âge préscolaire (MeSH), Essais contrôlés randomisés comme sujet (MeSH), Femelle (MeSH), Humains (MeSH), Infections communautaires (virologie), Infections communautaires (épidémiologie), Infections de l'appareil respiratoire (virologie), Infections de l'appareil respiratoire (épidémiologie), Maladies virales (diagnostic), Maladies virales (épidémiologie), Metapneumovirus (génétique), Metapneumovirus (isolement et purification), Mâle (MeSH), Nourrisson (MeSH), Partie nasale du pharynx (virologie), Pneumopathie virale (diagnostic), Pneumopathie virale (épidémiologie), Rhinovirus (génétique), Rhinovirus (isolement et purification), Virus (génétique), Virus (isolement et purification), Virus respiratoires syncytiaux (génétique), Virus respiratoires syncytiaux (isolement et purification), Études prospectives (MeSH).
MESH :
- diagnostic : Maladies virales, Pneumopathie virale.
- génétique : Coronavirus, Metapneumovirus, Rhinovirus, Virus, Virus respiratoires syncytiaux.
- isolement et purification : Coronavirus, Metapneumovirus, Rhinovirus, Virus, Virus respiratoires syncytiaux.
- virologie : Co-infection, Infections communautaires, Infections de l'appareil respiratoire, Partie nasale du pharynx.
- épidémiologie : Brésil, Co-infection, Infections communautaires, Infections de l'appareil respiratoire, Maladies virales, Pneumopathie virale.
- Enfant d'âge préscolaire, Essais contrôlés randomisés comme sujet, Femelle, Humains, Mâle, Nourrisson, Études prospectives.
Wicri :
- geographic : Brésil.

English descriptors

KwdEn :
- Brazil (epidemiology), Child, Preschool (MeSH), Coinfection (epidemiology), Coinfection (virology), Community-Acquired Infections (epidemiology), Community-Acquired Infections (virology), Coronavirus (genetics), Coronavirus (isolation & purification), Female (MeSH), Humans (MeSH), Infant (MeSH), Male (MeSH), Metapneumovirus (genetics), Metapneumovirus (isolation & purification), Nasopharynx (virology), Pneumonia, Viral (diagnosis), Pneumonia, Viral (epidemiology), Prospective Studies (MeSH), Randomized Controlled Trials as Topic (MeSH), Respiratory Syncytial Viruses (genetics), Respiratory Syncytial Viruses (isolation & purification), Respiratory Tract Infections (epidemiology), Respiratory Tract Infections (virology), Rhinovirus (genetics), Rhinovirus (isolation & purification), Virus Diseases (diagnosis), Virus Diseases (epidemiology), Viruses (genetics), Viruses (isolation & purification).
MESH :
- geographic , epidemiology : Brazil.
- diagnosis : Pneumonia, Viral, Virus Diseases.
- epidemiology : Coinfection, Community-Acquired Infections, Pneumonia, Viral, Respiratory Tract Infections, Virus Diseases.
- genetics : Coronavirus, Metapneumovirus, Respiratory Syncytial Viruses, Rhinovirus, Viruses.
- isolation & purification : Coronavirus, Metapneumovirus, Respiratory Syncytial Viruses, Rhinovirus, Viruses.
- virology : Coinfection, Community-Acquired Infections, Nasopharynx, Respiratory Tract Infections.
- Child, Preschool, Female, Humans, Infant, Male, Prospective Studies, Randomized Controlled Trials as Topic.

Abstract

BACKGROUND

Community-acquired pneumonia (CAP) causes a major burden to the health care system among children under-5 years worldwide. Information on respiratory viruses in non-severe CAP cases is scarce.

OBJECTIVES

To estimate the frequency of respiratory viruses among non-severe CAP cases.

STUDY DESIGN

Prospective study conducted in Salvador, Brazil. Out of 820 children aged 2-59 months with non-severe CAP diagnosed by pediatricians (respiratory complaints and radiographic pulmonary infiltrate/consolidation), recruited in a clinical trial (ClinicalTrials.gov Identifier NCT01200706), nasopharyngeal aspirate samples were obtained from 774 (94.4%) patients and tested for 16 respiratory viruses by PCRs.

RESULTS

Viruses were detected in 708 (91.5%; 95%CI: 89.3-93.3) cases, out of which 491 (69.4%; 95%CI: 65.9-72.7) harbored multiple viruses. Rhinovirus (46.1%; 95%CI: 42.6-49.6), adenovirus (38.4%; 95%CI: 35.0-41.8), and enterovirus (26.5%; 95%CI: 23.5-29.7) were the most commonly found viruses. The most frequent combination comprised rhinovirus plus adenovirus. No difference was found in the frequency of RSVA (16.1% vs. 14.6%; P = 0.6), RSVB (10.9% vs. 13.2%; P = 0.4) influenza (Flu) A (6.3% vs. 5.1%; P = 0.5), FluB (4.5% vs. 1.8%; P = 0.09), parainfluenza virus (PIV) 1 (5.1% vs. 2.8%; P = 0.2), or PIV4 (7.7% vs. 4.1%; P = 0.08), when children with multiple or sole virus detection were compared. Conversely, rhinovirus, adenovirus, enterovirus, bocavirus, PIV2, PIV3, metapneumovirus, coronavirus OC43, NL63, 229E were significantly more frequent among cases with multiple virus detection.

CONCLUSIONS

Respiratory viruses were detected in over 90% of the cases, out of which 70% had multiple viruses. Several viruses are more commonly found in multiple virus detection whereas other viruses are similarly found in sole and in multiple virus detection.

DOI: 10.1016/j.jcv.2018.06.003
PubMed: 29908521
PubMed Central: PMC7106541

Affiliations:

Links toward previous steps (curation, corpus...)

to stream Main, to step Corpus: 000047
to stream Main, to step Curation: 000047

Le document en format XML

<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Respiratory viruses among children with non-severe community-acquired pneumonia: A prospective cohort study.</title>
<author><name sortKey="Nascimento Carvalho, Amanda C" sort="Nascimento Carvalho, Amanda C" uniqKey="Nascimento Carvalho A" first="Amanda C" last="Nascimento-Carvalho">Amanda C. Nascimento-Carvalho</name>
<affiliation wicri:level="1"><nlm:affiliation>Bahiana School of Medicine, Bahiana Foundation for Science Development, Salvador, Brazil. Electronic address: carvalhoacn@hotmail.com.</nlm:affiliation>
<country xml:lang="fr">Brésil</country>
<wicri:regionArea>Bahiana School of Medicine, Bahiana Foundation for Science Development, Salvador</wicri:regionArea>
<wicri:noRegion>Salvador</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Vilas Boas, Ana Luisa" sort="Vilas Boas, Ana Luisa" uniqKey="Vilas Boas A" first="Ana-Luisa" last="Vilas-Boas">Ana-Luisa Vilas-Boas</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Pediatrics, Federal University of Bahia School of Medicine, Salvador, Brazil. Electronic address: anapediatria@ig.com.br.</nlm:affiliation>
<country xml:lang="fr">Brésil</country>
<wicri:regionArea>Department of Pediatrics, Federal University of Bahia School of Medicine, Salvador</wicri:regionArea>
<wicri:noRegion>Salvador</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Fontoura, Maria Socorro H" sort="Fontoura, Maria Socorro H" uniqKey="Fontoura M" first="Maria-Socorro H" last="Fontoura">Maria-Socorro H. Fontoura</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Pediatrics, Federal University of Bahia School of Medicine, Salvador, Brazil. Electronic address: fontora@uol.com.br.</nlm:affiliation>
<country xml:lang="fr">Brésil</country>
<wicri:regionArea>Department of Pediatrics, Federal University of Bahia School of Medicine, Salvador</wicri:regionArea>
<wicri:noRegion>Salvador</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Vuorinen, Tytti" sort="Vuorinen, Tytti" uniqKey="Vuorinen T" first="Tytti" last="Vuorinen">Tytti Vuorinen</name>
<affiliation wicri:level="3"><nlm:affiliation>Department of Clinical Virology, Turku University Hospital, Department of Virology, Turku University, Turku, Finland. Electronic address: tyvuori@utu.fi.</nlm:affiliation>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Department of Clinical Virology, Turku University Hospital, Department of Virology, Turku University, Turku</wicri:regionArea>
<placeName><settlement type="city">Turku</settlement>
<region type="région" nuts="2">Finlande occidentale</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Nascimento Carvalho, Cristiana M" sort="Nascimento Carvalho, Cristiana M" uniqKey="Nascimento Carvalho C" first="Cristiana M" last="Nascimento-Carvalho">Cristiana M. Nascimento-Carvalho</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Pediatrics, Federal University of Bahia School of Medicine, Salvador, Brazil. Electronic address: nascimentocarvalho@hotmail.com.</nlm:affiliation>
<country xml:lang="fr">Brésil</country>
<wicri:regionArea>Department of Pediatrics, Federal University of Bahia School of Medicine, Salvador</wicri:regionArea>
<wicri:noRegion>Salvador</wicri:noRegion>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PubMed</idno>
<date when="2018">2018</date>
<idno type="RBID">pubmed:29908521</idno>
<idno type="pmid">29908521</idno>
<idno type="doi">10.1016/j.jcv.2018.06.003</idno>
<idno type="pmc">PMC7106541</idno>
<idno type="wicri:Area/Main/Corpus">000047</idno>
<idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Corpus" wicri:corpus="PubMed">000047</idno>
<idno type="wicri:Area/Main/Curation">000047</idno>
<idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Curation">000047</idno>
<idno type="wicri:Area/Main/Exploration">000047</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en">Respiratory viruses among children with non-severe community-acquired pneumonia: A prospective cohort study.</title>
<author><name sortKey="Nascimento Carvalho, Amanda C" sort="Nascimento Carvalho, Amanda C" uniqKey="Nascimento Carvalho A" first="Amanda C" last="Nascimento-Carvalho">Amanda C. Nascimento-Carvalho</name>
<affiliation wicri:level="1"><nlm:affiliation>Bahiana School of Medicine, Bahiana Foundation for Science Development, Salvador, Brazil. Electronic address: carvalhoacn@hotmail.com.</nlm:affiliation>
<country xml:lang="fr">Brésil</country>
<wicri:regionArea>Bahiana School of Medicine, Bahiana Foundation for Science Development, Salvador</wicri:regionArea>
<wicri:noRegion>Salvador</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Vilas Boas, Ana Luisa" sort="Vilas Boas, Ana Luisa" uniqKey="Vilas Boas A" first="Ana-Luisa" last="Vilas-Boas">Ana-Luisa Vilas-Boas</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Pediatrics, Federal University of Bahia School of Medicine, Salvador, Brazil. Electronic address: anapediatria@ig.com.br.</nlm:affiliation>
<country xml:lang="fr">Brésil</country>
<wicri:regionArea>Department of Pediatrics, Federal University of Bahia School of Medicine, Salvador</wicri:regionArea>
<wicri:noRegion>Salvador</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Fontoura, Maria Socorro H" sort="Fontoura, Maria Socorro H" uniqKey="Fontoura M" first="Maria-Socorro H" last="Fontoura">Maria-Socorro H. Fontoura</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Pediatrics, Federal University of Bahia School of Medicine, Salvador, Brazil. Electronic address: fontora@uol.com.br.</nlm:affiliation>
<country xml:lang="fr">Brésil</country>
<wicri:regionArea>Department of Pediatrics, Federal University of Bahia School of Medicine, Salvador</wicri:regionArea>
<wicri:noRegion>Salvador</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Vuorinen, Tytti" sort="Vuorinen, Tytti" uniqKey="Vuorinen T" first="Tytti" last="Vuorinen">Tytti Vuorinen</name>
<affiliation wicri:level="3"><nlm:affiliation>Department of Clinical Virology, Turku University Hospital, Department of Virology, Turku University, Turku, Finland. Electronic address: tyvuori@utu.fi.</nlm:affiliation>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Department of Clinical Virology, Turku University Hospital, Department of Virology, Turku University, Turku</wicri:regionArea>
<placeName><settlement type="city">Turku</settlement>
<region type="région" nuts="2">Finlande occidentale</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Nascimento Carvalho, Cristiana M" sort="Nascimento Carvalho, Cristiana M" uniqKey="Nascimento Carvalho C" first="Cristiana M" last="Nascimento-Carvalho">Cristiana M. Nascimento-Carvalho</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Pediatrics, Federal University of Bahia School of Medicine, Salvador, Brazil. Electronic address: nascimentocarvalho@hotmail.com.</nlm:affiliation>
<country xml:lang="fr">Brésil</country>
<wicri:regionArea>Department of Pediatrics, Federal University of Bahia School of Medicine, Salvador</wicri:regionArea>
<wicri:noRegion>Salvador</wicri:noRegion>
</affiliation>
</author>
</analytic>
<series><title level="j">Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology</title>
<idno type="eISSN">1873-5967</idno>
<imprint><date when="2018" type="published">2018</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Brazil (epidemiology)</term>
<term>Child, Preschool (MeSH)</term>
<term>Coinfection (epidemiology)</term>
<term>Coinfection (virology)</term>
<term>Community-Acquired Infections (epidemiology)</term>
<term>Community-Acquired Infections (virology)</term>
<term>Coronavirus (genetics)</term>
<term>Coronavirus (isolation & purification)</term>
<term>Female (MeSH)</term>
<term>Humans (MeSH)</term>
<term>Infant (MeSH)</term>
<term>Male (MeSH)</term>
<term>Metapneumovirus (genetics)</term>
<term>Metapneumovirus (isolation & purification)</term>
<term>Nasopharynx (virology)</term>
<term>Pneumonia, Viral (diagnosis)</term>
<term>Pneumonia, Viral (epidemiology)</term>
<term>Prospective Studies (MeSH)</term>
<term>Randomized Controlled Trials as Topic (MeSH)</term>
<term>Respiratory Syncytial Viruses (genetics)</term>
<term>Respiratory Syncytial Viruses (isolation & purification)</term>
<term>Respiratory Tract Infections (epidemiology)</term>
<term>Respiratory Tract Infections (virology)</term>
<term>Rhinovirus (genetics)</term>
<term>Rhinovirus (isolation & purification)</term>
<term>Virus Diseases (diagnosis)</term>
<term>Virus Diseases (epidemiology)</term>
<term>Viruses (genetics)</term>
<term>Viruses (isolation & purification)</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Brésil (épidémiologie)</term>
<term>Co-infection (virologie)</term>
<term>Co-infection (épidémiologie)</term>
<term>Coronavirus (génétique)</term>
<term>Coronavirus (isolement et purification)</term>
<term>Enfant d'âge préscolaire (MeSH)</term>
<term>Essais contrôlés randomisés comme sujet (MeSH)</term>
<term>Femelle (MeSH)</term>
<term>Humains (MeSH)</term>
<term>Infections communautaires (virologie)</term>
<term>Infections communautaires (épidémiologie)</term>
<term>Infections de l'appareil respiratoire (virologie)</term>
<term>Infections de l'appareil respiratoire (épidémiologie)</term>
<term>Maladies virales (diagnostic)</term>
<term>Maladies virales (épidémiologie)</term>
<term>Metapneumovirus (génétique)</term>
<term>Metapneumovirus (isolement et purification)</term>
<term>Mâle (MeSH)</term>
<term>Nourrisson (MeSH)</term>
<term>Partie nasale du pharynx (virologie)</term>
<term>Pneumopathie virale (diagnostic)</term>
<term>Pneumopathie virale (épidémiologie)</term>
<term>Rhinovirus (génétique)</term>
<term>Rhinovirus (isolement et purification)</term>
<term>Virus (génétique)</term>
<term>Virus (isolement et purification)</term>
<term>Virus respiratoires syncytiaux (génétique)</term>
<term>Virus respiratoires syncytiaux (isolement et purification)</term>
<term>Études prospectives (MeSH)</term>
</keywords>
<keywords scheme="MESH" type="geographic" qualifier="epidemiology" xml:lang="en"><term>Brazil</term>
</keywords>
<keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Pneumonia, Viral</term>
<term>Virus Diseases</term>
</keywords>
<keywords scheme="MESH" qualifier="diagnostic" xml:lang="fr"><term>Maladies virales</term>
<term>Pneumopathie virale</term>
</keywords>
<keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Coinfection</term>
<term>Community-Acquired Infections</term>
<term>Pneumonia, Viral</term>
<term>Respiratory Tract Infections</term>
<term>Virus Diseases</term>
</keywords>
<keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Coronavirus</term>
<term>Metapneumovirus</term>
<term>Respiratory Syncytial Viruses</term>
<term>Rhinovirus</term>
<term>Viruses</term>
</keywords>
<keywords scheme="MESH" qualifier="génétique" xml:lang="fr"><term>Coronavirus</term>
<term>Metapneumovirus</term>
<term>Rhinovirus</term>
<term>Virus</term>
<term>Virus respiratoires syncytiaux</term>
</keywords>
<keywords scheme="MESH" qualifier="isolation & purification" xml:lang="en"><term>Coronavirus</term>
<term>Metapneumovirus</term>
<term>Respiratory Syncytial Viruses</term>
<term>Rhinovirus</term>
<term>Viruses</term>
</keywords>
<keywords scheme="MESH" qualifier="isolement et purification" xml:lang="fr"><term>Coronavirus</term>
<term>Metapneumovirus</term>
<term>Rhinovirus</term>
<term>Virus</term>
<term>Virus respiratoires syncytiaux</term>
</keywords>
<keywords scheme="MESH" qualifier="virologie" xml:lang="fr"><term>Co-infection</term>
<term>Infections communautaires</term>
<term>Infections de l'appareil respiratoire</term>
<term>Partie nasale du pharynx</term>
</keywords>
<keywords scheme="MESH" qualifier="virology" xml:lang="en"><term>Coinfection</term>
<term>Community-Acquired Infections</term>
<term>Nasopharynx</term>
<term>Respiratory Tract Infections</term>
</keywords>
<keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr"><term>Brésil</term>
<term>Co-infection</term>
<term>Infections communautaires</term>
<term>Infections de l'appareil respiratoire</term>
<term>Maladies virales</term>
<term>Pneumopathie virale</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Child, Preschool</term>
<term>Female</term>
<term>Humans</term>
<term>Infant</term>
<term>Male</term>
<term>Prospective Studies</term>
<term>Randomized Controlled Trials as Topic</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>Enfant d'âge préscolaire</term>
<term>Essais contrôlés randomisés comme sujet</term>
<term>Femelle</term>
<term>Humains</term>
<term>Mâle</term>
<term>Nourrisson</term>
<term>Études prospectives</term>
</keywords>
<keywords scheme="Wicri" type="geographic" xml:lang="fr"><term>Brésil</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en"><p><b>BACKGROUND</b>
</p>
<p>Community-acquired pneumonia (CAP) causes a major burden to the health care system among children under-5 years worldwide. Information on respiratory viruses in non-severe CAP cases is scarce.</p>
</div>
<div type="abstract" xml:lang="en"><p><b>OBJECTIVES</b>
</p>
<p>To estimate the frequency of respiratory viruses among non-severe CAP cases.</p>
</div>
<div type="abstract" xml:lang="en"><p><b>STUDY DESIGN</b>
</p>
<p>Prospective study conducted in Salvador, Brazil. Out of 820 children aged 2-59 months with non-severe CAP diagnosed by pediatricians (respiratory complaints and radiographic pulmonary infiltrate/consolidation), recruited in a clinical trial (ClinicalTrials.gov Identifier NCT01200706), nasopharyngeal aspirate samples were obtained from 774 (94.4%) patients and tested for 16 respiratory viruses by PCRs.</p>
</div>
<div type="abstract" xml:lang="en"><p><b>RESULTS</b>
</p>
<p>Viruses were detected in 708 (91.5%; 95%CI: 89.3-93.3) cases, out of which 491 (69.4%; 95%CI: 65.9-72.7) harbored multiple viruses. Rhinovirus (46.1%; 95%CI: 42.6-49.6), adenovirus (38.4%; 95%CI: 35.0-41.8), and enterovirus (26.5%; 95%CI: 23.5-29.7) were the most commonly found viruses. The most frequent combination comprised rhinovirus plus adenovirus. No difference was found in the frequency of RSVA (16.1% vs. 14.6%; P = 0.6), RSVB (10.9% vs. 13.2%; P = 0.4) influenza (Flu) A (6.3% vs. 5.1%; P = 0.5), FluB (4.5% vs. 1.8%; P = 0.09), parainfluenza virus (PIV) 1 (5.1% vs. 2.8%; P = 0.2), or PIV4 (7.7% vs. 4.1%; P = 0.08), when children with multiple or sole virus detection were compared. Conversely, rhinovirus, adenovirus, enterovirus, bocavirus, PIV2, PIV3, metapneumovirus, coronavirus OC43, NL63, 229E were significantly more frequent among cases with multiple virus detection.</p>
</div>
<div type="abstract" xml:lang="en"><p><b>CONCLUSIONS</b>
</p>
<p>Respiratory viruses were detected in over 90% of the cases, out of which 70% had multiple viruses. Several viruses are more commonly found in multiple virus detection whereas other viruses are similarly found in sole and in multiple virus detection.</p>
</div>
</front>
</TEI>
<pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">29908521</PMID>
<DateCompleted><Year>2019</Year>
<Month>04</Month>
<Day>29</Day>
</DateCompleted>
<DateRevised><Year>2020</Year>
<Month>06</Month>
<Day>05</Day>
</DateRevised>
<Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1873-5967</ISSN>
<JournalIssue CitedMedium="Internet"><Volume>105</Volume>
<PubDate><Year>2018</Year>
<Month>08</Month>
</PubDate>
</JournalIssue>
<Title>Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology</Title>
<ISOAbbreviation>J. Clin. Virol.</ISOAbbreviation>
</Journal>
<ArticleTitle>Respiratory viruses among children with non-severe community-acquired pneumonia: A prospective cohort study.</ArticleTitle>
<Pagination><MedlinePgn>77-83</MedlinePgn>
</Pagination>
<ELocationID EIdType="pii" ValidYN="Y">S1386-6532(18)30153-7</ELocationID>
<ELocationID EIdType="doi" ValidYN="Y">10.1016/j.jcv.2018.06.003</ELocationID>
<Abstract><AbstractText Label="BACKGROUND">Community-acquired pneumonia (CAP) causes a major burden to the health care system among children under-5 years worldwide. Information on respiratory viruses in non-severe CAP cases is scarce.</AbstractText>
<AbstractText Label="OBJECTIVES">To estimate the frequency of respiratory viruses among non-severe CAP cases.</AbstractText>
<AbstractText Label="STUDY DESIGN">Prospective study conducted in Salvador, Brazil. Out of 820 children aged 2-59 months with non-severe CAP diagnosed by pediatricians (respiratory complaints and radiographic pulmonary infiltrate/consolidation), recruited in a clinical trial (ClinicalTrials.gov Identifier NCT01200706), nasopharyngeal aspirate samples were obtained from 774 (94.4%) patients and tested for 16 respiratory viruses by PCRs.</AbstractText>
<AbstractText Label="RESULTS">Viruses were detected in 708 (91.5%; 95%CI: 89.3-93.3) cases, out of which 491 (69.4%; 95%CI: 65.9-72.7) harbored multiple viruses. Rhinovirus (46.1%; 95%CI: 42.6-49.6), adenovirus (38.4%; 95%CI: 35.0-41.8), and enterovirus (26.5%; 95%CI: 23.5-29.7) were the most commonly found viruses. The most frequent combination comprised rhinovirus plus adenovirus. No difference was found in the frequency of RSVA (16.1% vs. 14.6%; P = 0.6), RSVB (10.9% vs. 13.2%; P = 0.4) influenza (Flu) A (6.3% vs. 5.1%; P = 0.5), FluB (4.5% vs. 1.8%; P = 0.09), parainfluenza virus (PIV) 1 (5.1% vs. 2.8%; P = 0.2), or PIV4 (7.7% vs. 4.1%; P = 0.08), when children with multiple or sole virus detection were compared. Conversely, rhinovirus, adenovirus, enterovirus, bocavirus, PIV2, PIV3, metapneumovirus, coronavirus OC43, NL63, 229E were significantly more frequent among cases with multiple virus detection.</AbstractText>
<AbstractText Label="CONCLUSIONS">Respiratory viruses were detected in over 90% of the cases, out of which 70% had multiple viruses. Several viruses are more commonly found in multiple virus detection whereas other viruses are similarly found in sole and in multiple virus detection.</AbstractText>
<CopyrightInformation>Copyright © 2018 Elsevier B.V. All rights reserved.</CopyrightInformation>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Nascimento-Carvalho</LastName>
<ForeName>Amanda C</ForeName>
<Initials>AC</Initials>
<AffiliationInfo><Affiliation>Bahiana School of Medicine, Bahiana Foundation for Science Development, Salvador, Brazil. Electronic address: carvalhoacn@hotmail.com.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Vilas-Boas</LastName>
<ForeName>Ana-Luisa</ForeName>
<Initials>AL</Initials>
<AffiliationInfo><Affiliation>Department of Pediatrics, Federal University of Bahia School of Medicine, Salvador, Brazil. Electronic address: anapediatria@ig.com.br.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Fontoura</LastName>
<ForeName>Maria-Socorro H</ForeName>
<Initials>MH</Initials>
<AffiliationInfo><Affiliation>Department of Pediatrics, Federal University of Bahia School of Medicine, Salvador, Brazil. Electronic address: fontora@uol.com.br.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Vuorinen</LastName>
<ForeName>Tytti</ForeName>
<Initials>T</Initials>
<AffiliationInfo><Affiliation>Department of Clinical Virology, Turku University Hospital, Department of Virology, Turku University, Turku, Finland. Electronic address: tyvuori@utu.fi.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Nascimento-Carvalho</LastName>
<ForeName>Cristiana M</ForeName>
<Initials>CM</Initials>
<AffiliationInfo><Affiliation>Department of Pediatrics, Federal University of Bahia School of Medicine, Salvador, Brazil. Electronic address: nascimentocarvalho@hotmail.com.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><CollectiveName>PNEUMOPAC-Efficacy Study Group</CollectiveName>
</Author>
</AuthorList>
<Language>eng</Language>
<DataBankList CompleteYN="Y"><DataBank><DataBankName>ClinicalTrials.gov</DataBankName>
<AccessionNumberList><AccessionNumber>NCT01200706</AccessionNumber>
</AccessionNumberList>
</DataBank>
</DataBankList>
<PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType>
<PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType>
</PublicationTypeList>
<ArticleDate DateType="Electronic"><Year>2018</Year>
<Month>06</Month>
<Day>06</Day>
</ArticleDate>
</Article>
<MedlineJournalInfo><Country>Netherlands</Country>
<MedlineTA>J Clin Virol</MedlineTA>
<NlmUniqueID>9815671</NlmUniqueID>
<ISSNLinking>1386-6532</ISSNLinking>
</MedlineJournalInfo>
<CitationSubset>IM</CitationSubset>
<MeshHeadingList><MeshHeading><DescriptorName UI="D001938" MajorTopicYN="N" Type="Geographic">Brazil</DescriptorName>
<QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D002675" MajorTopicYN="N">Child, Preschool</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D060085" MajorTopicYN="N">Coinfection</DescriptorName>
<QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName>
<QualifierName UI="Q000821" MajorTopicYN="N">virology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D017714" MajorTopicYN="N">Community-Acquired Infections</DescriptorName>
<QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName>
<QualifierName UI="Q000821" MajorTopicYN="Y">virology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D017934" MajorTopicYN="N">Coronavirus</DescriptorName>
<QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName>
<QualifierName UI="Q000302" MajorTopicYN="N">isolation & purification</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D007223" MajorTopicYN="N">Infant</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D029121" MajorTopicYN="N">Metapneumovirus</DescriptorName>
<QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName>
<QualifierName UI="Q000302" MajorTopicYN="N">isolation & purification</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D009305" MajorTopicYN="N">Nasopharynx</DescriptorName>
<QualifierName UI="Q000821" MajorTopicYN="N">virology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D011024" MajorTopicYN="N">Pneumonia, Viral</DescriptorName>
<QualifierName UI="Q000175" MajorTopicYN="N">diagnosis</QualifierName>
<QualifierName UI="Q000453" MajorTopicYN="Y">epidemiology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D011446" MajorTopicYN="N">Prospective Studies</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D016032" MajorTopicYN="N">Randomized Controlled Trials as Topic</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D012136" MajorTopicYN="N">Respiratory Syncytial Viruses</DescriptorName>
<QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName>
<QualifierName UI="Q000302" MajorTopicYN="N">isolation & purification</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D012141" MajorTopicYN="N">Respiratory Tract Infections</DescriptorName>
<QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName>
<QualifierName UI="Q000821" MajorTopicYN="N">virology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D012229" MajorTopicYN="N">Rhinovirus</DescriptorName>
<QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName>
<QualifierName UI="Q000302" MajorTopicYN="N">isolation & purification</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D014777" MajorTopicYN="N">Virus Diseases</DescriptorName>
<QualifierName UI="Q000175" MajorTopicYN="N">diagnosis</QualifierName>
<QualifierName UI="Q000453" MajorTopicYN="Y">epidemiology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D014780" MajorTopicYN="N">Viruses</DescriptorName>
<QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName>
<QualifierName UI="Q000302" MajorTopicYN="Y">isolation & purification</QualifierName>
</MeshHeading>
</MeshHeadingList>
<KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="Y">Acute respiratory infection</Keyword>
<Keyword MajorTopicYN="Y">Children</Keyword>
<Keyword MajorTopicYN="Y">Lower tract respiratory infection</Keyword>
<Keyword MajorTopicYN="Y">Respiratory virus</Keyword>
<Keyword MajorTopicYN="Y">Viral infection</Keyword>
</KeywordList>
</MedlineCitation>
<PubmedData><History><PubMedPubDate PubStatus="received"><Year>2018</Year>
<Month>05</Month>
<Day>18</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="revised"><Year>2018</Year>
<Month>06</Month>
<Day>01</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="accepted"><Year>2018</Year>
<Month>06</Month>
<Day>05</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="pubmed"><Year>2018</Year>
<Month>6</Month>
<Day>17</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="medline"><Year>2019</Year>
<Month>4</Month>
<Day>30</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="entrez"><Year>2018</Year>
<Month>6</Month>
<Day>17</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
</History>
<PublicationStatus>ppublish</PublicationStatus>
<ArticleIdList><ArticleId IdType="pubmed">29908521</ArticleId>
<ArticleId IdType="pii">S1386-6532(18)30153-7</ArticleId>
<ArticleId IdType="doi">10.1016/j.jcv.2018.06.003</ArticleId>
<ArticleId IdType="pmc">PMC7106541</ArticleId>
</ArticleIdList>
<ReferenceList><Reference><Citation>Paediatr Respir Rev. 2014 Dec;15(4):363-70</Citation>
<ArticleIdList><ArticleId IdType="pubmed">24361079</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Thorax. 2015 Sep;70(9):847-53</Citation>
<ArticleIdList><ArticleId IdType="pubmed">26077969</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Infect Dis. 2016 Feb 15;213(4):584-91</Citation>
<ArticleIdList><ArticleId IdType="pubmed">26180044</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Antimicrob Chemother. 2014 Jul;69(7):1954-9</Citation>
<ArticleIdList><ArticleId IdType="pubmed">24648506</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Pediatr Pulmonol. 2018 Jan;53(1):88-94</Citation>
<ArticleIdList><ArticleId IdType="pubmed">29028159</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Chest. 2010 Oct;138(4):811-6</Citation>
<ArticleIdList><ArticleId IdType="pubmed">20363845</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Infect. 2017 Jun;74 Suppl 1:S143-S146</Citation>
<ArticleIdList><ArticleId IdType="pubmed">28646954</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Infect Dis. 2008 Feb 1;197(3):382-9</Citation>
<ArticleIdList><ArticleId IdType="pubmed">18248302</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Bull World Health Organ. 2005 May;83(5):353-9</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15976876</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Clin Infect Dis. 2017 Jun 15;64(suppl_3):S205-S212</Citation>
<ArticleIdList><ArticleId IdType="pubmed">28575354</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Bull World Health Organ. 2008 May;86(5):408-16</Citation>
<ArticleIdList><ArticleId IdType="pubmed">18545744</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Lancet. 2011 Apr 9;377(9773):1264-75</Citation>
<ArticleIdList><ArticleId IdType="pubmed">21435708</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Clin Microbiol Infect. 2012 Mar;18(3):300-7</Citation>
<ArticleIdList><ArticleId IdType="pubmed">21851481</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Virol Sin. 2013 Apr;28(2):97-102</Citation>
<ArticleIdList><ArticleId IdType="pubmed">23575731</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Med Virol. 2013 Jan;85(1):138-43</Citation>
<ArticleIdList><ArticleId IdType="pubmed">23097275</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Lancet. 2013 Apr 20;381(9875):1405-1416</Citation>
<ArticleIdList><ArticleId IdType="pubmed">23582727</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Clin Microbiol. 2016 Dec 28;55(1):79-89</Citation>
<ArticleIdList><ArticleId IdType="pubmed">27795341</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Infect Dis Clin North Am. 2013 Mar;27(1):157-75</Citation>
<ArticleIdList><ArticleId IdType="pubmed">23398872</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Clin Infect Dis. 2017 Aug 15;65(4):604-612</Citation>
<ArticleIdList><ArticleId IdType="pubmed">28605562</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Pediatr Allergy Immunol. 2014 Dec;25(8):796-803</Citation>
<ArticleIdList><ArticleId IdType="pubmed">25444257</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Diagn Microbiol Infect Dis. 2014 Aug;79(4):419-21</Citation>
<ArticleIdList><ArticleId IdType="pubmed">24985763</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Clin Microbiol. 2015 Apr;53(4):1172-7</Citation>
<ArticleIdList><ArticleId IdType="pubmed">25631799</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Clin Infect Dis. 2001 Mar 1;32(5):715-26</Citation>
<ArticleIdList><ArticleId IdType="pubmed">11229839</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Pediatr Infect Dis J. 2012 Aug;31(8):808-13</Citation>
<ArticleIdList><ArticleId IdType="pubmed">22531244</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
</PubmedData>
</pubmed>
<affiliations><list><country><li>Brésil</li>
<li>Finlande</li>
</country>
<region><li>Finlande occidentale</li>
</region>
<settlement><li>Turku</li>
</settlement>
</list>
<tree><country name="Brésil"><noRegion><name sortKey="Nascimento Carvalho, Amanda C" sort="Nascimento Carvalho, Amanda C" uniqKey="Nascimento Carvalho A" first="Amanda C" last="Nascimento-Carvalho">Amanda C. Nascimento-Carvalho</name>
</noRegion>
<name sortKey="Fontoura, Maria Socorro H" sort="Fontoura, Maria Socorro H" uniqKey="Fontoura M" first="Maria-Socorro H" last="Fontoura">Maria-Socorro H. Fontoura</name>
<name sortKey="Nascimento Carvalho, Cristiana M" sort="Nascimento Carvalho, Cristiana M" uniqKey="Nascimento Carvalho C" first="Cristiana M" last="Nascimento-Carvalho">Cristiana M. Nascimento-Carvalho</name>
<name sortKey="Vilas Boas, Ana Luisa" sort="Vilas Boas, Ana Luisa" uniqKey="Vilas Boas A" first="Ana-Luisa" last="Vilas-Boas">Ana-Luisa Vilas-Boas</name>
</country>
<country name="Finlande"><region name="Finlande occidentale"><name sortKey="Vuorinen, Tytti" sort="Vuorinen, Tytti" uniqKey="Vuorinen T" first="Tytti" last="Vuorinen">Tytti Vuorinen</name>
</region>
</country>
</tree>
</affiliations>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Sante/explor/GrippeBresilV2/Data/Main/Exploration

HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000051 | SxmlIndent | more

HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000051 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Sante
   |area=    GrippeBresilV2
   |flux=    Main
   |étape=   Exploration
   |type=    RBID
   |clé=     pubmed:29908521
   |texte=   Respiratory viruses among children with non-severe community-acquired pneumonia: A prospective cohort study.
}}

Pour générer des pages wiki

HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i   -Sk "pubmed:29908521" \
       | HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd   \
       | NlmPubMed2Wicri -a GrippeBresilV2

This area was generated with Dilib version V0.6.36.
Data generation: Thu Aug 27 08:25:44 2020. Site generation: Sat Mar 27 15:44:06 2021

	Serveur d'exploration sur la grippe au Brésil
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.

Serveur d'exploration sur la grippe au Brésil

Respiratory viruses among children with non-severe community-acquired pneumonia: A prospective cohort study.

Respiratory viruses among children with non-severe community-acquired pneumonia: A prospective cohort study.

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki