Burden of influenza in Germany: a retrospective claims database analysis for the influenza season 2012/2013.
Identifieur interne : 000128 ( Main/Corpus ); précédent : 000127; suivant : 000129Burden of influenza in Germany: a retrospective claims database analysis for the influenza season 2012/2013.
Auteurs : Jennifer Haas ; Sebastian Braun ; Peter WutzlerSource :
- The European journal of health economics : HEPAC : health economics in prevention and care [ 1618-7601 ] ; 2016.
English descriptors
- KwdEn :
- Adolescent (MeSH), Adult (MeSH), Age Distribution (MeSH), Anti-Bacterial Agents (economics), Anti-Bacterial Agents (therapeutic use), Antitussive Agents (economics), Antitussive Agents (therapeutic use), Child (MeSH), Child, Preschool (MeSH), Cost of Illness (MeSH), Databases, Factual (MeSH), Female (MeSH), Germany (epidemiology), Health Care Costs (statistics & numerical data), Hospital Costs (MeSH), Hospitalization (economics), Humans (MeSH), Infant (MeSH), Influenza Vaccines (therapeutic use), Influenza, Human (drug therapy), Influenza, Human (economics), Influenza, Human (epidemiology), Influenza, Human (prevention & control), Insurance Claim Reporting (MeSH), Male (MeSH), Middle Aged (MeSH), Otitis Media (economics), Otitis Media (epidemiology), Pneumonia (economics), Pneumonia (epidemiology), Retrospective Studies (MeSH), Seasons (MeSH).
- MESH :
- chemical , economics : Anti-Bacterial Agents, Antitussive Agents.
- chemical , therapeutic use : Anti-Bacterial Agents, Antitussive Agents, Influenza Vaccines.
- drug therapy : Influenza, Human.
- economics : Hospitalization, Influenza, Human, Otitis Media, Pneumonia.
- epidemiology : Germany, Influenza, Human, Otitis Media, Pneumonia.
- prevention & control : Influenza, Human.
- statistics & numerical data : Health Care Costs.
- Adolescent, Adult, Age Distribution, Child, Child, Preschool, Cost of Illness, Databases, Factual, Female, Hospital Costs, Humans, Infant, Insurance Claim Reporting, Male, Middle Aged, Retrospective Studies, Seasons.
Abstract
OBJECTIVE
Seasonal influenza occurs in annual epidemics. The virus can cause severe illness and concomitant diseases with the highest risk for children, the elderly, and individuals with disease dispositions. The study objective is to assess the influenza burden in Germany.
METHODS
This retrospective claims data analysis used the Health Risk Institute research database containing anonymized data of 4 million individuals. The study period comprised the influenza season 2012/2013 in which patients with documented influenza were identified. Disease frequency rates were calculated for a population with disease dispositions and a population not at high risk. Disease burden was assessed based on health-services utilization during the influenza season. Vaccine rates were calculated by identifying vaccinations.
RESULTS
We observed 65,826 patients with influenza, resulting in 1,160,646 documented influenza cases after extrapolation. Overall, otitis media and pneumonia was higher in the influenza-infected population compared to the non-influenza-infected population and especially high in children. Hospitalization cost amounted to €87,202,485 with a mean stay of 7 days, and total outpatient costs were €14,947,976. Vaccination rates were <4 % for children and 37 % for patients aged >60.
CONCLUSIONS
Seasonal influenza can cause severe outcomes with hospitalizations and excess costs. Especially influenza-infected children are affected by concomitant diseases with higher disease burden. Furthermore, documented vaccination rates are quite low.
DOI: 10.1007/s10198-015-0708-7
PubMed: 26143025
PubMed Central: PMC4899503
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pubmed:26143025Le document en format XML
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07745, Jena, Germany.</nlm:affiliation></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2016">2016</date><idno type="RBID">pubmed:26143025</idno><idno type="pmid">26143025</idno><idno type="doi">10.1007/s10198-015-0708-7</idno><idno type="pmc">PMC4899503</idno><idno type="wicri:Area/Main/Corpus">000128</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Corpus" wicri:corpus="PubMed">000128</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Burden of influenza in Germany: a retrospective claims database analysis for the influenza season 2012/2013.</title><author><name sortKey="Haas, Jennifer" sort="Haas, Jennifer" uniqKey="Haas J" first="Jennifer" last="Haas">Jennifer Haas</name><affiliation><nlm:affiliation>Xcenda GmbH, Lange Laube 31, 30159, Hannover, Germany. jennifer.haas@xcenda.de.</nlm:affiliation></affiliation></author><author><name sortKey="Braun, Sebastian" sort="Braun, Sebastian" uniqKey="Braun S" first="Sebastian" last="Braun">Sebastian Braun</name><affiliation><nlm:affiliation>Xcenda GmbH, Lange Laube 31, 30159, Hannover, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Wutzler, Peter" sort="Wutzler, Peter" uniqKey="Wutzler P" first="Peter" last="Wutzler">Peter Wutzler</name><affiliation><nlm:affiliation>Institute of Virology and Antiviral Therapy, Jena University Hospital, Friedrich-Schiller University, Hans-Knöll-Str. 2, 07745, Jena, Germany.</nlm:affiliation></affiliation></author></analytic><series><title level="j">The European journal of health economics : HEPAC : health economics in prevention and care</title><idno type="eISSN">1618-7601</idno><imprint><date when="2016" type="published">2016</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adolescent (MeSH)</term><term>Adult (MeSH)</term><term>Age Distribution (MeSH)</term><term>Anti-Bacterial Agents (economics)</term><term>Anti-Bacterial Agents (therapeutic use)</term><term>Antitussive Agents (economics)</term><term>Antitussive Agents (therapeutic use)</term><term>Child (MeSH)</term><term>Child, Preschool (MeSH)</term><term>Cost of Illness (MeSH)</term><term>Databases, Factual (MeSH)</term><term>Female (MeSH)</term><term>Germany (epidemiology)</term><term>Health Care Costs (statistics & numerical data)</term><term>Hospital Costs (MeSH)</term><term>Hospitalization (economics)</term><term>Humans (MeSH)</term><term>Infant (MeSH)</term><term>Influenza Vaccines (therapeutic use)</term><term>Influenza, Human (drug therapy)</term><term>Influenza, Human (economics)</term><term>Influenza, Human (epidemiology)</term><term>Influenza, Human (prevention & control)</term><term>Insurance Claim Reporting (MeSH)</term><term>Male (MeSH)</term><term>Middle Aged (MeSH)</term><term>Otitis Media (economics)</term><term>Otitis Media (epidemiology)</term><term>Pneumonia (economics)</term><term>Pneumonia (epidemiology)</term><term>Retrospective Studies (MeSH)</term><term>Seasons (MeSH)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="economics" xml:lang="en"><term>Anti-Bacterial Agents</term><term>Antitussive Agents</term></keywords><keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Anti-Bacterial Agents</term><term>Antitussive Agents</term><term>Influenza Vaccines</term></keywords><keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Influenza, Human</term></keywords><keywords scheme="MESH" qualifier="economics" xml:lang="en"><term>Hospitalization</term><term>Influenza, Human</term><term>Otitis Media</term><term>Pneumonia</term></keywords><keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Germany</term><term>Influenza, Human</term><term>Otitis Media</term><term>Pneumonia</term></keywords><keywords scheme="MESH" qualifier="prevention & control" xml:lang="en"><term>Influenza, Human</term></keywords><keywords scheme="MESH" qualifier="statistics & numerical data" xml:lang="en"><term>Health Care Costs</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adolescent</term><term>Adult</term><term>Age Distribution</term><term>Child</term><term>Child, Preschool</term><term>Cost of Illness</term><term>Databases, Factual</term><term>Female</term><term>Hospital Costs</term><term>Humans</term><term>Infant</term><term>Insurance Claim Reporting</term><term>Male</term><term>Middle Aged</term><term>Retrospective Studies</term><term>Seasons</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p><b>OBJECTIVE</b></p><p>Seasonal influenza occurs in annual epidemics. The virus can cause severe illness and concomitant diseases with the highest risk for children, the elderly, and individuals with disease dispositions. The study objective is to assess the influenza burden in Germany.</p></div><div type="abstract" xml:lang="en"><p><b>METHODS</b></p><p>This retrospective claims data analysis used the Health Risk Institute research database containing anonymized data of 4 million individuals. The study period comprised the influenza season 2012/2013 in which patients with documented influenza were identified. Disease frequency rates were calculated for a population with disease dispositions and a population not at high risk. Disease burden was assessed based on health-services utilization during the influenza season. Vaccine rates were calculated by identifying vaccinations.</p></div><div type="abstract" xml:lang="en"><p><b>RESULTS</b></p><p>We observed 65,826 patients with influenza, resulting in 1,160,646 documented influenza cases after extrapolation. Overall, otitis media and pneumonia was higher in the influenza-infected population compared to the non-influenza-infected population and especially high in children. Hospitalization cost amounted to €87,202,485 with a mean stay of 7 days, and total outpatient costs were €14,947,976. Vaccination rates were <4 % for children and 37 % for patients aged >60.</p></div><div type="abstract" xml:lang="en"><p><b>CONCLUSIONS</b></p><p>Seasonal influenza can cause severe outcomes with hospitalizations and excess costs. Especially influenza-infected children are affected by concomitant diseases with higher disease burden. Furthermore, documented vaccination rates are quite low.</p></div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">26143025</PMID><DateCompleted><Year>2017</Year><Month>05</Month><Day>19</Day></DateCompleted><DateRevised><Year>2018</Year><Month>11</Month><Day>13</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1618-7601</ISSN><JournalIssue CitedMedium="Internet"><Volume>17</Volume><Issue>6</Issue><PubDate><Year>2016</Year><Month>Jul</Month></PubDate></JournalIssue><Title>The European journal of health economics : HEPAC : health economics in prevention and care</Title><ISOAbbreviation>Eur J Health Econ</ISOAbbreviation></Journal><ArticleTitle>Burden of influenza in Germany: a retrospective claims database analysis for the influenza season 2012/2013.</ArticleTitle><Pagination><MedlinePgn>669-79</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1007/s10198-015-0708-7</ELocationID><Abstract><AbstractText Label="OBJECTIVE" NlmCategory="OBJECTIVE">Seasonal influenza occurs in annual epidemics. The virus can cause severe illness and concomitant diseases with the highest risk for children, the elderly, and individuals with disease dispositions. The study objective is to assess the influenza burden in Germany.</AbstractText><AbstractText Label="METHODS" NlmCategory="METHODS">This retrospective claims data analysis used the Health Risk Institute research database containing anonymized data of 4 million individuals. The study period comprised the influenza season 2012/2013 in which patients with documented influenza were identified. Disease frequency rates were calculated for a population with disease dispositions and a population not at high risk. Disease burden was assessed based on health-services utilization during the influenza season. Vaccine rates were calculated by identifying vaccinations.</AbstractText><AbstractText Label="RESULTS" NlmCategory="RESULTS">We observed 65,826 patients with influenza, resulting in 1,160,646 documented influenza cases after extrapolation. Overall, otitis media and pneumonia was higher in the influenza-infected population compared to the non-influenza-infected population and especially high in children. Hospitalization cost amounted to €87,202,485 with a mean stay of 7 days, and total outpatient costs were €14,947,976. Vaccination rates were <4 % for children and 37 % for patients aged >60.</AbstractText><AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">Seasonal influenza can cause severe outcomes with hospitalizations and excess costs. Especially influenza-infected children are affected by concomitant diseases with higher disease burden. 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