Retrospective analysis of clinical and virological parameters of influenza cases at four university hospitals in Germany, 2015.
Identifieur interne : 000060 ( Main/Corpus ); précédent : 000059; suivant : 000061Retrospective analysis of clinical and virological parameters of influenza cases at four university hospitals in Germany, 2015.
Auteurs : Robert Heyd ; Anna Maria Eis-Hübinger ; Annemarie Berger ; Sibylle Bierbaum ; Sandra Pietzonka ; Jürgen J. Wenzel ; Daniela Huzly ; Oliver T. Keppler ; Marcus PanningSource :
- Infection [ 1439-0973 ] ; 2017.
English descriptors
- KwdEn :
- Adult (MeSH), Aged (MeSH), Cross Infection (epidemiology), Cross Infection (virology), Female (MeSH), Germany (epidemiology), Hospitals, University (MeSH), Humans (MeSH), Influenza A Virus, H1N1 Subtype (isolation & purification), Influenza A Virus, H1N1 Subtype (physiology), Influenza A Virus, H3N2 Subtype (isolation & purification), Influenza A Virus, H3N2 Subtype (physiology), Influenza, Human (epidemiology), Influenza, Human (virology), Male (MeSH), Middle Aged (MeSH), Prevalence (MeSH), Retrospective Studies (MeSH).
- MESH :
- epidemiology : Cross Infection, Germany, Influenza, Human.
- isolation & purification : Influenza A Virus, H1N1 Subtype, Influenza A Virus, H3N2 Subtype.
- physiology : Influenza A Virus, H1N1 Subtype, Influenza A Virus, H3N2 Subtype.
- virology : Cross Infection, Influenza, Human.
- Adult, Aged, Female, Hospitals, University, Humans, Male, Middle Aged, Prevalence, Retrospective Studies.
Abstract
We conducted a retrospective observational study at four German university hospitals of patients with laboratory-confirmed influenza in 2014/2015. Overall, a fatality rate of 8% was observed. Significantly more A(H1N1)pdm09 patients were admitted to ICU compared to those with A(H3N2). However, fatal outcome was not significantly increased among A(H1N1)pdm09 cases. Nosocomial infections were seen in 17% of cases. Systematic collection of data from hospitals will complement national influenza surveillance.
DOI: 10.1007/s15010-017-1008-1
PubMed: 28316058
Links to Exploration step
pubmed:28316058Le document en format XML
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Wenzel</name><affiliation><nlm:affiliation>Institute of Clinical Microbiology and Hygiene, Regensburg University Medical Centre, Regensburg, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Huzly, Daniela" sort="Huzly, Daniela" uniqKey="Huzly D" first="Daniela" last="Huzly">Daniela Huzly</name><affiliation><nlm:affiliation>Institute for Virology, Medical Center - University of Freiburg, Hermann-Herder-Str. 11, 79014, Freiburg, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Keppler, Oliver T" sort="Keppler, Oliver T" uniqKey="Keppler O" first="Oliver T" last="Keppler">Oliver T. Keppler</name><affiliation><nlm:affiliation>Institute of Virology, University of Bonn Medical Centre, Bonn, Germany.</nlm:affiliation></affiliation><affiliation><nlm:affiliation>Max von Pettenkofer-Institut, Virology, Ludwig Maximilian University of Munich, Munich, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Panning, Marcus" sort="Panning, Marcus" uniqKey="Panning M" first="Marcus" last="Panning">Marcus Panning</name><affiliation><nlm:affiliation>Institute for Virology, Medical Center - University of Freiburg, Hermann-Herder-Str. 11, 79014, Freiburg, Germany. marcus.panning@uniklinik-freiburg.de.</nlm:affiliation></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2017">2017</date><idno type="RBID">pubmed:28316058</idno><idno type="pmid">28316058</idno><idno type="doi">10.1007/s15010-017-1008-1</idno><idno type="wicri:Area/Main/Corpus">000060</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Corpus" wicri:corpus="PubMed">000060</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Retrospective analysis of clinical and virological parameters of influenza cases at four university hospitals in Germany, 2015.</title><author><name sortKey="Heyd, Robert" sort="Heyd, Robert" uniqKey="Heyd R" first="Robert" last="Heyd">Robert Heyd</name><affiliation><nlm:affiliation>Institute of Clinical Microbiology and Hygiene, Regensburg University Medical Centre, Regensburg, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Eis Hubinger, Anna Maria" sort="Eis Hubinger, Anna Maria" uniqKey="Eis Hubinger A" first="Anna Maria" last="Eis-Hübinger">Anna Maria Eis-Hübinger</name><affiliation><nlm:affiliation>Institute of Virology, University of Bonn Medical Centre, Bonn, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Berger, Annemarie" sort="Berger, Annemarie" uniqKey="Berger A" first="Annemarie" last="Berger">Annemarie Berger</name><affiliation><nlm:affiliation>Institute for Medical Virology, University Hospital Frankfurt, Frankfurt am Main, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Bierbaum, Sibylle" sort="Bierbaum, Sibylle" uniqKey="Bierbaum S" first="Sibylle" last="Bierbaum">Sibylle Bierbaum</name><affiliation><nlm:affiliation>Institute for Virology, Medical Center - University of Freiburg, Hermann-Herder-Str. 11, 79014, Freiburg, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Pietzonka, Sandra" sort="Pietzonka, Sandra" uniqKey="Pietzonka S" first="Sandra" last="Pietzonka">Sandra Pietzonka</name><affiliation><nlm:affiliation>Institute of Virology, University of Bonn Medical Centre, Bonn, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Wenzel, Jurgen J" sort="Wenzel, Jurgen J" uniqKey="Wenzel J" first="Jürgen J" last="Wenzel">Jürgen J. Wenzel</name><affiliation><nlm:affiliation>Institute of Clinical Microbiology and Hygiene, Regensburg University Medical Centre, Regensburg, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Huzly, Daniela" sort="Huzly, Daniela" uniqKey="Huzly D" first="Daniela" last="Huzly">Daniela Huzly</name><affiliation><nlm:affiliation>Institute for Virology, Medical Center - University of Freiburg, Hermann-Herder-Str. 11, 79014, Freiburg, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Keppler, Oliver T" sort="Keppler, Oliver T" uniqKey="Keppler O" first="Oliver T" last="Keppler">Oliver T. Keppler</name><affiliation><nlm:affiliation>Institute of Virology, University of Bonn Medical Centre, Bonn, Germany.</nlm:affiliation></affiliation><affiliation><nlm:affiliation>Max von Pettenkofer-Institut, Virology, Ludwig Maximilian University of Munich, Munich, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Panning, Marcus" sort="Panning, Marcus" uniqKey="Panning M" first="Marcus" last="Panning">Marcus Panning</name><affiliation><nlm:affiliation>Institute for Virology, Medical Center - University of Freiburg, Hermann-Herder-Str. 11, 79014, Freiburg, Germany. marcus.panning@uniklinik-freiburg.de.</nlm:affiliation></affiliation></author></analytic><series><title level="j">Infection</title><idno type="eISSN">1439-0973</idno><imprint><date when="2017" type="published">2017</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult (MeSH)</term><term>Aged (MeSH)</term><term>Cross Infection (epidemiology)</term><term>Cross Infection (virology)</term><term>Female (MeSH)</term><term>Germany (epidemiology)</term><term>Hospitals, University (MeSH)</term><term>Humans (MeSH)</term><term>Influenza A Virus, H1N1 Subtype (isolation & purification)</term><term>Influenza A Virus, H1N1 Subtype (physiology)</term><term>Influenza A Virus, H3N2 Subtype (isolation & purification)</term><term>Influenza A Virus, H3N2 Subtype (physiology)</term><term>Influenza, Human (epidemiology)</term><term>Influenza, Human (virology)</term><term>Male (MeSH)</term><term>Middle Aged (MeSH)</term><term>Prevalence (MeSH)</term><term>Retrospective Studies (MeSH)</term></keywords><keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Cross Infection</term><term>Germany</term><term>Influenza, Human</term></keywords><keywords scheme="MESH" qualifier="isolation & purification" xml:lang="en"><term>Influenza A Virus, H1N1 Subtype</term><term>Influenza A Virus, H3N2 Subtype</term></keywords><keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Influenza A Virus, H1N1 Subtype</term><term>Influenza A Virus, H3N2 Subtype</term></keywords><keywords scheme="MESH" qualifier="virology" xml:lang="en"><term>Cross Infection</term><term>Influenza, Human</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adult</term><term>Aged</term><term>Female</term><term>Hospitals, University</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Prevalence</term><term>Retrospective Studies</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">We conducted a retrospective observational study at four German university hospitals of patients with laboratory-confirmed influenza in 2014/2015. Overall, a fatality rate of 8% was observed. Significantly more A(H1N1)pdm09 patients were admitted to ICU compared to those with A(H3N2). However, fatal outcome was not significantly increased among A(H1N1)pdm09 cases. Nosocomial infections were seen in 17% of cases. Systematic collection of data from hospitals will complement national influenza surveillance.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">28316058</PMID><DateCompleted><Year>2017</Year><Month>12</Month><Day>13</Day></DateCompleted><DateRevised><Year>2018</Year><Month>11</Month><Day>13</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1439-0973</ISSN><JournalIssue CitedMedium="Internet"><Volume>45</Volume><Issue>3</Issue><PubDate><Year>2017</Year><Month>Jun</Month></PubDate></JournalIssue><Title>Infection</Title><ISOAbbreviation>Infection</ISOAbbreviation></Journal><ArticleTitle>Retrospective analysis of clinical and virological parameters of influenza cases at four university hospitals in Germany, 2015.</ArticleTitle><Pagination><MedlinePgn>349-354</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1007/s15010-017-1008-1</ELocationID><Abstract><AbstractText>We conducted a retrospective observational study at four German university hospitals of patients with laboratory-confirmed influenza in 2014/2015. Overall, a fatality rate of 8% was observed. Significantly more A(H1N1)pdm09 patients were admitted to ICU compared to those with A(H3N2). However, fatal outcome was not significantly increased among A(H1N1)pdm09 cases. Nosocomial infections were seen in 17% of cases. Systematic collection of data from hospitals will complement national influenza surveillance.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Heyd</LastName><ForeName>Robert</ForeName><Initials>R</Initials><AffiliationInfo><Affiliation>Institute of Clinical Microbiology and Hygiene, Regensburg University Medical Centre, Regensburg, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Eis-Hübinger</LastName><ForeName>Anna Maria</ForeName><Initials>AM</Initials><AffiliationInfo><Affiliation>Institute of Virology, University of Bonn Medical Centre, Bonn, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Berger</LastName><ForeName>Annemarie</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Institute for Medical Virology, University Hospital Frankfurt, Frankfurt am Main, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Bierbaum</LastName><ForeName>Sibylle</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Institute for Virology, Medical Center - University of Freiburg, Hermann-Herder-Str. 11, 79014, Freiburg, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Pietzonka</LastName><ForeName>Sandra</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Institute of Virology, University of Bonn Medical Centre, Bonn, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Wenzel</LastName><ForeName>Jürgen J</ForeName><Initials>JJ</Initials><AffiliationInfo><Affiliation>Institute of Clinical Microbiology and Hygiene, Regensburg University Medical Centre, Regensburg, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Huzly</LastName><ForeName>Daniela</ForeName><Initials>D</Initials><AffiliationInfo><Affiliation>Institute for Virology, Medical Center - University of Freiburg, Hermann-Herder-Str. 11, 79014, Freiburg, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Keppler</LastName><ForeName>Oliver T</ForeName><Initials>OT</Initials><AffiliationInfo><Affiliation>Institute of Virology, University of Bonn Medical Centre, Bonn, Germany.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Max von Pettenkofer-Institut, Virology, Ludwig Maximilian University of Munich, Munich, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Panning</LastName><ForeName>Marcus</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Institute for Virology, Medical Center - University of Freiburg, Hermann-Herder-Str. 11, 79014, Freiburg, Germany. marcus.panning@uniklinik-freiburg.de.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2017</Year><Month>03</Month><Day>18</Day></ArticleDate></Article><MedlineJournalInfo><Country>Germany</Country><MedlineTA>Infection</MedlineTA><NlmUniqueID>0365307</NlmUniqueID><ISSNLinking>0300-8126</ISSNLinking></MedlineJournalInfo><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000328" MajorTopicYN="N">Adult</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000368" MajorTopicYN="N">Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D003428" MajorTopicYN="N">Cross Infection</DescriptorName><QualifierName UI="Q000453" MajorTopicYN="Y">epidemiology</QualifierName><QualifierName UI="Q000821" MajorTopicYN="Y">virology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D005858" MajorTopicYN="N">Germany</DescriptorName><QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D006785" MajorTopicYN="N">Hospitals, University</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D053118" MajorTopicYN="N">Influenza A Virus, H1N1 Subtype</DescriptorName><QualifierName UI="Q000302" MajorTopicYN="N">isolation & purification</QualifierName><QualifierName UI="Q000502" MajorTopicYN="Y">physiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D053122" MajorTopicYN="N">Influenza A Virus, H3N2 Subtype</DescriptorName><QualifierName UI="Q000302" MajorTopicYN="N">isolation & purification</QualifierName><QualifierName UI="Q000502" MajorTopicYN="Y">physiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D007251" MajorTopicYN="N">Influenza, Human</DescriptorName><QualifierName UI="Q000453" MajorTopicYN="Y">epidemiology</QualifierName><QualifierName UI="Q000821" MajorTopicYN="Y">virology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D015995" MajorTopicYN="N">Prevalence</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D012189" MajorTopicYN="N">Retrospective Studies</DescriptorName></MeshHeading></MeshHeadingList><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">Epidemiology</Keyword><Keyword MajorTopicYN="N">Influenza</Keyword><Keyword MajorTopicYN="N">Nosocomial</Keyword><Keyword MajorTopicYN="N">Observational study</Keyword><Keyword MajorTopicYN="N">University hospital</Keyword></KeywordList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2016</Year><Month>09</Month><Day>02</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2017</Year><Month>03</Month><Day>13</Day></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2017</Year><Month>3</Month><Day>21</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2017</Year><Month>12</Month><Day>14</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2017</Year><Month>3</Month><Day>20</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">28316058</ArticleId><ArticleId IdType="doi">10.1007/s15010-017-1008-1</ArticleId><ArticleId IdType="pii">10.1007/s15010-017-1008-1</ArticleId></ArticleIdList><ReferenceList><Reference><Citation>Clin Transplant. 2015 Oct;29(10):938-43</Citation><ArticleIdList><ArticleId IdType="pubmed">26338182</ArticleId></ArticleIdList></Reference><Reference><Citation>J Clin Virol. 2015 Oct;71:44-50</Citation><ArticleIdList><ArticleId 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