Molecular epidemiology of porcine H3N2 influenza A viruses isolated in Germany between 1982 and 2001.
Identifieur interne : 000506 ( Main/Exploration ); précédent : 000505; suivant : 000507Molecular epidemiology of porcine H3N2 influenza A viruses isolated in Germany between 1982 and 2001.
Auteurs : Christina Schrader [Allemagne] ; Jochen SüssSource :
- Intervirology [ 0300-5526 ] ; 2004.
Descripteurs français
- KwdFr :
- ARN viral (génétique), ARN viral (isolement et purification), Allemagne (épidémiologie), Analyse de séquence d'ADN, Animaux, Glycoprotéine hémagglutinine du virus influenza (génétique), Gènes viraux, Infections de l'appareil respiratoire (médecine vétérinaire), Infections de l'appareil respiratoire (virologie), Infections de l'appareil respiratoire (épidémiologie), Infections à Orthomyxoviridae (médecine vétérinaire), Infections à Orthomyxoviridae (épidémiologie), Maladies des porcs (virologie), Maladies des porcs (épidémiologie), Phylogénie, RT-PCR, Sialidase (génétique), Similitude de séquences d'acides nucléiques, Sous-type H3N2 du virus de la grippe A, Suidae, Variation génétique, Virus de la grippe A (génétique), Virus de la grippe A (isolement et purification), Épidémiologie moléculaire.
- MESH :
- génétique : ARN viral, Glycoprotéine hémagglutinine du virus influenza, Sialidase, Virus de la grippe A.
- isolement et purification : ARN viral, Virus de la grippe A.
- médecine vétérinaire : Infections de l'appareil respiratoire, Infections à Orthomyxoviridae.
- virologie : Infections de l'appareil respiratoire, Maladies des porcs.
- épidémiologie : Allemagne, Infections de l'appareil respiratoire, Infections à Orthomyxoviridae, Maladies des porcs.
- Analyse de séquence d'ADN, Animaux, Gènes viraux, Phylogénie, RT-PCR, Similitude de séquences d'acides nucléiques, Sous-type H3N2 du virus de la grippe A, Suidae, Variation génétique, Épidémiologie moléculaire.
- Wicri :
- geographic : Allemagne.
English descriptors
- KwdEn :
- Animals, Genes, Viral, Genetic Variation, Germany (epidemiology), Hemagglutinin Glycoproteins, Influenza Virus (genetics), Influenza A Virus, H3N2 Subtype, Influenza A virus (genetics), Influenza A virus (isolation & purification), Molecular Epidemiology, Neuraminidase (genetics), Orthomyxoviridae Infections (epidemiology), Orthomyxoviridae Infections (veterinary), Phylogeny, RNA, Viral (genetics), RNA, Viral (isolation & purification), Respiratory Tract Infections (epidemiology), Respiratory Tract Infections (veterinary), Respiratory Tract Infections (virology), Reverse Transcriptase Polymerase Chain Reaction, Sequence Analysis, DNA, Sequence Homology, Nucleic Acid, Swine, Swine Diseases (epidemiology), Swine Diseases (virology).
- MESH :
- chemical , genetics : Hemagglutinin Glycoproteins, Influenza Virus, Neuraminidase, RNA, Viral.
- geographic , epidemiology : Germany.
- epidemiology : Orthomyxoviridae Infections, Respiratory Tract Infections, Swine Diseases.
- genetics : Influenza A virus.
- isolation & purification : Influenza A virus, RNA, Viral.
- veterinary : Orthomyxoviridae Infections, Respiratory Tract Infections.
- virology : Respiratory Tract Infections, Swine Diseases.
- Animals, Genes, Viral, Genetic Variation, Influenza A Virus, H3N2 Subtype, Molecular Epidemiology, Phylogeny, Reverse Transcriptase Polymerase Chain Reaction, Sequence Analysis, DNA, Sequence Homology, Nucleic Acid, Swine.
Abstract
We examined influenza virus strains of the subtype H3N2 from outbreaks of respiratory diseases in swine herds in Germany. Four different clusters can be distinguished when comparing parts of the HA1 gene from porcine H3N2 isolates analyzed between 1982 and 2001. Comparison between these clusters reveals a bp homology of less than 90%. In contrast, the homology within the clusters is between 93.7 and 100%. Each of these clusters was confined to a specific time period. For the NA gene an additional cluster is formed by the porcine H1N2 isolate. The findings that different subtypes and drift variants are circulating in the German pig population explain the emergence of new influenza virus variants and the need for continued surveillance of swine.
DOI: 10.1159/000077829
PubMed: 15192270
Affiliations:
Links toward previous steps (curation, corpus...)
Le document en format XML
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<term>Animaux</term>
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<term>Similitude de séquences d'acides nucléiques</term>
<term>Sous-type H3N2 du virus de la grippe A</term>
<term>Suidae</term>
<term>Variation génétique</term>
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<term>Infections à Orthomyxoviridae</term>
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<term>RT-PCR</term>
<term>Similitude de séquences d'acides nucléiques</term>
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<front><div type="abstract" xml:lang="en">We examined influenza virus strains of the subtype H3N2 from outbreaks of respiratory diseases in swine herds in Germany. Four different clusters can be distinguished when comparing parts of the HA1 gene from porcine H3N2 isolates analyzed between 1982 and 2001. Comparison between these clusters reveals a bp homology of less than 90%. In contrast, the homology within the clusters is between 93.7 and 100%. Each of these clusters was confined to a specific time period. For the NA gene an additional cluster is formed by the porcine H1N2 isolate. The findings that different subtypes and drift variants are circulating in the German pig population explain the emergence of new influenza virus variants and the need for continued surveillance of swine.</div>
</front>
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<Abstract><AbstractText>We examined influenza virus strains of the subtype H3N2 from outbreaks of respiratory diseases in swine herds in Germany. Four different clusters can be distinguished when comparing parts of the HA1 gene from porcine H3N2 isolates analyzed between 1982 and 2001. Comparison between these clusters reveals a bp homology of less than 90%. In contrast, the homology within the clusters is between 93.7 and 100%. Each of these clusters was confined to a specific time period. For the NA gene an additional cluster is formed by the porcine H1N2 isolate. The findings that different subtypes and drift variants are circulating in the German pig population explain the emergence of new influenza virus variants and the need for continued surveillance of swine.</AbstractText>
<CopyrightInformation>Copyright 2004 S. Karger AG, Basel</CopyrightInformation>
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