Pandemic A/H1N1(2009) influenza infections in very-low-birth-weight infants--a case series from the German Neonatal Network.
Identifieur interne : 000274 ( Main/Exploration ); précédent : 000273; suivant : 000275Pandemic A/H1N1(2009) influenza infections in very-low-birth-weight infants--a case series from the German Neonatal Network.
Auteurs : A. Stein [Allemagne] ; M. Keller ; S. Ross ; M. Roggendorf ; F. Heitmann ; T. Hoehn ; W. Göpel ; U. Felderhoff-Müser ; C. H RtelSource :
- Klinische Padiatrie [ 1439-3824 ] ; 2011.
Descripteurs français
- KwdFr :
- Allemagne, Antiviraux (usage thérapeutique), Cause de décès, Diagnostic différentiel, Facteurs de risque, Femelle, Grippe humaine (diagnostic), Grippe humaine (mortalité), Grippe humaine (transmission), Grippe humaine (étiologie), Humains, Infection croisée (diagnostic), Infection croisée (mortalité), Infection croisée (transmission), Infection croisée (étiologie), Maladies du prématuré (diagnostic), Maladies du prématuré (mortalité), Maladies du prématuré (traitement médicamenteux), Mâle, Nourrisson de poids extrêmement faible à la naissance, Nourrisson très faible poids naissance, Nouveau-né, Oséltamivir (usage thérapeutique), Pneumopathie virale (diagnostic), Pneumopathie virale (mortalité), Pneumopathie virale (traitement médicamenteux), Pneumopathie virale (transmission), Sepsie (diagnostic), Sepsie (mortalité), Sepsie (traitement médicamenteux), Sous-type H1N1 du virus de la grippe A, Syndrome de détresse respiratoire du nouveau-né (diagnostic), Syndrome de détresse respiratoire du nouveau-né (mortalité), Syndrome de détresse respiratoire du nouveau-né (traitement médicamenteux), Taux de survie, Âge gestationnel.
- MESH :
- diagnostic : Grippe humaine, Infection croisée, Maladies du prématuré, Pneumopathie virale, Sepsie, Syndrome de détresse respiratoire du nouveau-né.
- mortalité : Grippe humaine, Infection croisée, Maladies du prématuré, Pneumopathie virale, Sepsie, Syndrome de détresse respiratoire du nouveau-né.
- traitement médicamenteux : Maladies du prématuré, Pneumopathie virale, Sepsie, Syndrome de détresse respiratoire du nouveau-né.
- usage thérapeutique : Antiviraux, Grippe humaine, Infection croisée, Oséltamivir, Pneumopathie virale.
- étiologie : Grippe humaine, Infection croisée.
- Allemagne, Cause de décès, Diagnostic différentiel, Facteurs de risque, Femelle, Humains, Mâle, Nourrisson de poids extrêmement faible à la naissance, Nourrisson très faible poids naissance, Nouveau-né, Sous-type H1N1 du virus de la grippe A, Taux de survie, Âge gestationnel.
- Wicri :
- geographic : Allemagne.
English descriptors
- KwdEn :
- Antiviral Agents (therapeutic use), Cause of Death, Cross Infection (diagnosis), Cross Infection (etiology), Cross Infection (mortality), Cross Infection (transmission), Diagnosis, Differential, Female, Germany, Gestational Age, Humans, Infant, Extremely Low Birth Weight, Infant, Newborn, Infant, Premature, Diseases (diagnosis), Infant, Premature, Diseases (drug therapy), Infant, Premature, Diseases (mortality), Infant, Very Low Birth Weight, Influenza A Virus, H1N1 Subtype, Influenza, Human (diagnosis), Influenza, Human (etiology), Influenza, Human (mortality), Influenza, Human (transmission), Male, Oseltamivir (therapeutic use), Pneumonia, Viral (diagnosis), Pneumonia, Viral (drug therapy), Pneumonia, Viral (mortality), Pneumonia, Viral (transmission), Respiratory Distress Syndrome, Newborn (diagnosis), Respiratory Distress Syndrome, Newborn (drug therapy), Respiratory Distress Syndrome, Newborn (mortality), Risk Factors, Sepsis (diagnosis), Sepsis (drug therapy), Sepsis (mortality), Survival Rate.
- MESH :
- chemical , therapeutic use : Antiviral Agents, Oseltamivir.
- geographic : Germany.
- diagnosis : Cross Infection, Infant, Premature, Diseases, Influenza, Human, Pneumonia, Viral, Respiratory Distress Syndrome, Newborn, Sepsis.
- drug therapy : Infant, Premature, Diseases, Pneumonia, Viral, Respiratory Distress Syndrome, Newborn, Sepsis.
- etiology : Cross Infection, Influenza, Human.
- mortality : Cross Infection, Infant, Premature, Diseases, Influenza, Human, Pneumonia, Viral, Respiratory Distress Syndrome, Newborn, Sepsis.
- transmission : Cross Infection, Influenza, Human, Pneumonia, Viral.
- Cause of Death, Diagnosis, Differential, Female, Gestational Age, Humans, Infant, Extremely Low Birth Weight, Infant, Newborn, Infant, Very Low Birth Weight, Influenza A Virus, H1N1 Subtype, Male, Risk Factors, Survival Rate.
Abstract
6 cases of clinical influenza A/H1N1(2009) infections were reported within the multi-center German Neonatal Network (GNN) during the primary hospital stay in the pandemic season 2009/2010 and 2010/2011. Clinical symptoms varied from transient hyperthermia to apnea and severe respiratory distress. 1 fatal course with systemic inflammatory response after perinatal transmission of A/H1N1(2009) was observed. Oseltamivir treatment in 3/6 infants was without side effects. The reported cases have major implications for the management of VLBW infants: i) fatal courses after perinatal transmission are possible, ii) postnatal A/H1N1(2009) infection may result in life threatening events at a time when the infant is otherwise stable, iii) vaccination should be recommended for parents and medical staff to avoid nosocomial transmission, iv) more data are needed on the benefit and harm of antiviral drugs in preterm infants, v) neonatologists should suspect A/H1N1(2009) infection when unexplained sepsis-like or respiratory symptoms occur in VLBW infants.
DOI: 10.1055/s-0031-1285840
PubMed: 21913143
Affiliations:
Links toward previous steps (curation, corpus...)
Le document en format XML
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<term>Cross Infection (etiology)</term>
<term>Cross Infection (mortality)</term>
<term>Cross Infection (transmission)</term>
<term>Diagnosis, Differential</term>
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<term>Germany</term>
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<term>Infant, Premature, Diseases (drug therapy)</term>
<term>Infant, Premature, Diseases (mortality)</term>
<term>Infant, Very Low Birth Weight</term>
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<term>Influenza, Human (transmission)</term>
<term>Male</term>
<term>Oseltamivir (therapeutic use)</term>
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<term>Cause de décès</term>
<term>Diagnostic différentiel</term>
<term>Facteurs de risque</term>
<term>Femelle</term>
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<term>Grippe humaine (mortalité)</term>
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<term>Maladies du prématuré (traitement médicamenteux)</term>
<term>Mâle</term>
<term>Nourrisson de poids extrêmement faible à la naissance</term>
<term>Nourrisson très faible poids naissance</term>
<term>Nouveau-né</term>
<term>Oséltamivir (usage thérapeutique)</term>
<term>Pneumopathie virale (diagnostic)</term>
<term>Pneumopathie virale (mortalité)</term>
<term>Pneumopathie virale (traitement médicamenteux)</term>
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<term>Sepsie (mortalité)</term>
<term>Sepsie (traitement médicamenteux)</term>
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<term>Syndrome de détresse respiratoire du nouveau-né (diagnostic)</term>
<term>Syndrome de détresse respiratoire du nouveau-né (mortalité)</term>
<term>Syndrome de détresse respiratoire du nouveau-né (traitement médicamenteux)</term>
<term>Taux de survie</term>
<term>Âge gestationnel</term>
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<term>Oseltamivir</term>
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<term>Influenza, Human</term>
<term>Pneumonia, Viral</term>
<term>Respiratory Distress Syndrome, Newborn</term>
<term>Sepsis</term>
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<keywords scheme="MESH" qualifier="diagnostic" xml:lang="fr"><term>Grippe humaine</term>
<term>Infection croisée</term>
<term>Maladies du prématuré</term>
<term>Pneumopathie virale</term>
<term>Sepsie</term>
<term>Syndrome de détresse respiratoire du nouveau-né</term>
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<keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Infant, Premature, Diseases</term>
<term>Pneumonia, Viral</term>
<term>Respiratory Distress Syndrome, Newborn</term>
<term>Sepsis</term>
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<term>Influenza, Human</term>
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<term>Influenza, Human</term>
<term>Pneumonia, Viral</term>
<term>Respiratory Distress Syndrome, Newborn</term>
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<term>Infection croisée</term>
<term>Maladies du prématuré</term>
<term>Pneumopathie virale</term>
<term>Sepsie</term>
<term>Syndrome de détresse respiratoire du nouveau-né</term>
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<term>Pneumopathie virale</term>
<term>Sepsie</term>
<term>Syndrome de détresse respiratoire du nouveau-né</term>
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<term>Influenza, Human</term>
<term>Pneumonia, Viral</term>
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<term>Grippe humaine</term>
<term>Infection croisée</term>
<term>Oséltamivir</term>
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<term>Diagnosis, Differential</term>
<term>Female</term>
<term>Gestational Age</term>
<term>Humans</term>
<term>Infant, Extremely Low Birth Weight</term>
<term>Infant, Newborn</term>
<term>Infant, Very Low Birth Weight</term>
<term>Influenza A Virus, H1N1 Subtype</term>
<term>Male</term>
<term>Risk Factors</term>
<term>Survival Rate</term>
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<term>Cause de décès</term>
<term>Diagnostic différentiel</term>
<term>Facteurs de risque</term>
<term>Femelle</term>
<term>Humains</term>
<term>Mâle</term>
<term>Nourrisson de poids extrêmement faible à la naissance</term>
<term>Nourrisson très faible poids naissance</term>
<term>Nouveau-né</term>
<term>Sous-type H1N1 du virus de la grippe A</term>
<term>Taux de survie</term>
<term>Âge gestationnel</term>
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<front><div type="abstract" xml:lang="en">6 cases of clinical influenza A/H1N1(2009) infections were reported within the multi-center German Neonatal Network (GNN) during the primary hospital stay in the pandemic season 2009/2010 and 2010/2011. Clinical symptoms varied from transient hyperthermia to apnea and severe respiratory distress. 1 fatal course with systemic inflammatory response after perinatal transmission of A/H1N1(2009) was observed. Oseltamivir treatment in 3/6 infants was without side effects. The reported cases have major implications for the management of VLBW infants: i) fatal courses after perinatal transmission are possible, ii) postnatal A/H1N1(2009) infection may result in life threatening events at a time when the infant is otherwise stable, iii) vaccination should be recommended for parents and medical staff to avoid nosocomial transmission, iv) more data are needed on the benefit and harm of antiviral drugs in preterm infants, v) neonatologists should suspect A/H1N1(2009) infection when unexplained sepsis-like or respiratory symptoms occur in VLBW infants.</div>
</front>
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<DateCompleted><Year>2012</Year>
<Month>03</Month>
<Day>06</Day>
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<DateRevised><Year>2013</Year>
<Month>11</Month>
<Day>21</Day>
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<JournalIssue CitedMedium="Internet"><Volume>223</Volume>
<Issue>5</Issue>
<PubDate><Year>2011</Year>
<Month>Sep</Month>
</PubDate>
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<Title>Klinische Padiatrie</Title>
<ISOAbbreviation>Klin Padiatr</ISOAbbreviation>
</Journal>
<ArticleTitle>Pandemic A/H1N1(2009) influenza infections in very-low-birth-weight infants--a case series from the German Neonatal Network.</ArticleTitle>
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<Abstract><AbstractText>6 cases of clinical influenza A/H1N1(2009) infections were reported within the multi-center German Neonatal Network (GNN) during the primary hospital stay in the pandemic season 2009/2010 and 2010/2011. Clinical symptoms varied from transient hyperthermia to apnea and severe respiratory distress. 1 fatal course with systemic inflammatory response after perinatal transmission of A/H1N1(2009) was observed. Oseltamivir treatment in 3/6 infants was without side effects. The reported cases have major implications for the management of VLBW infants: i) fatal courses after perinatal transmission are possible, ii) postnatal A/H1N1(2009) infection may result in life threatening events at a time when the infant is otherwise stable, iii) vaccination should be recommended for parents and medical staff to avoid nosocomial transmission, iv) more data are needed on the benefit and harm of antiviral drugs in preterm infants, v) neonatologists should suspect A/H1N1(2009) infection when unexplained sepsis-like or respiratory symptoms occur in VLBW infants.</AbstractText>
<CopyrightInformation>George Thieme Verlag KG Stuttgart · New York.</CopyrightInformation>
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<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Stein</LastName>
<ForeName>A</ForeName>
<Initials>A</Initials>
<AffiliationInfo><Affiliation>Department of Pediatrics I, Neonatology, University Hospital Essen, Hufelandstrasse 55, Essen, Germany. anja.stein@uk-essen.de</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Keller</LastName>
<ForeName>M</ForeName>
<Initials>M</Initials>
</Author>
<Author ValidYN="Y"><LastName>Ross</LastName>
<ForeName>S</ForeName>
<Initials>S</Initials>
</Author>
<Author ValidYN="Y"><LastName>Roggendorf</LastName>
<ForeName>M</ForeName>
<Initials>M</Initials>
</Author>
<Author ValidYN="Y"><LastName>Heitmann</LastName>
<ForeName>F</ForeName>
<Initials>F</Initials>
</Author>
<Author ValidYN="Y"><LastName>Hoehn</LastName>
<ForeName>T</ForeName>
<Initials>T</Initials>
</Author>
<Author ValidYN="Y"><LastName>Göpel</LastName>
<ForeName>W</ForeName>
<Initials>W</Initials>
</Author>
<Author ValidYN="Y"><LastName>Felderhoff-Müser</LastName>
<ForeName>U</ForeName>
<Initials>U</Initials>
</Author>
<Author ValidYN="Y"><LastName>Härtel</LastName>
<ForeName>C</ForeName>
<Initials>C</Initials>
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<Month>09</Month>
<Day>12</Day>
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<MedlineTA>Klin Padiatr</MedlineTA>
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<ISSNLinking>0300-8630</ISSNLinking>
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<MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName>
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<QualifierName UI="Q000188" MajorTopicYN="N">drug therapy</QualifierName>
<QualifierName UI="Q000401" MajorTopicYN="N">mortality</QualifierName>
<QualifierName UI="Q000635" MajorTopicYN="N">transmission</QualifierName>
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<QualifierName UI="Q000401" MajorTopicYN="N">mortality</QualifierName>
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<MeshHeading><DescriptorName UI="D012307" MajorTopicYN="N">Risk Factors</DescriptorName>
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<MeshHeading><DescriptorName UI="D018805" MajorTopicYN="N">Sepsis</DescriptorName>
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<QualifierName UI="Q000188" MajorTopicYN="N">drug therapy</QualifierName>
<QualifierName UI="Q000401" MajorTopicYN="N">mortality</QualifierName>
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<MeshHeading><DescriptorName UI="D015996" MajorTopicYN="N">Survival Rate</DescriptorName>
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<PubmedData><History><PubMedPubDate PubStatus="entrez"><Year>2011</Year>
<Month>9</Month>
<Day>14</Day>
<Hour>6</Hour>
<Minute>0</Minute>
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<PubMedPubDate PubStatus="pubmed"><Year>2011</Year>
<Month>9</Month>
<Day>14</Day>
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<PubMedPubDate PubStatus="medline"><Year>2012</Year>
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<ArticleIdList><ArticleId IdType="pubmed">21913143</ArticleId>
<ArticleId IdType="doi">10.1055/s-0031-1285840</ArticleId>
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<affiliations><list><country><li>Allemagne</li>
</country>
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<tree><noCountry><name sortKey="Felderhoff Muser, U" sort="Felderhoff Muser, U" uniqKey="Felderhoff Muser U" first="U" last="Felderhoff-Müser">U. Felderhoff-Müser</name>
<name sortKey="Gopel, W" sort="Gopel, W" uniqKey="Gopel W" first="W" last="Göpel">W. Göpel</name>
<name sortKey="H Rtel, C" sort="H Rtel, C" uniqKey="H Rtel C" first="C" last="H Rtel">C. H Rtel</name>
<name sortKey="Heitmann, F" sort="Heitmann, F" uniqKey="Heitmann F" first="F" last="Heitmann">F. Heitmann</name>
<name sortKey="Hoehn, T" sort="Hoehn, T" uniqKey="Hoehn T" first="T" last="Hoehn">T. Hoehn</name>
<name sortKey="Keller, M" sort="Keller, M" uniqKey="Keller M" first="M" last="Keller">M. Keller</name>
<name sortKey="Roggendorf, M" sort="Roggendorf, M" uniqKey="Roggendorf M" first="M" last="Roggendorf">M. Roggendorf</name>
<name sortKey="Ross, S" sort="Ross, S" uniqKey="Ross S" first="S" last="Ross">S. Ross</name>
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<country name="Allemagne"><noRegion><name sortKey="Stein, A" sort="Stein, A" uniqKey="Stein A" first="A" last="Stein">A. Stein</name>
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