[Influenza--the last big epidemic. What makes it so dangerous?].
Identifieur interne : 000549 ( Main/Curation ); précédent : 000548; suivant : 000550[Influenza--the last big epidemic. What makes it so dangerous?].
Auteurs : W. Lange [Allemagne]Source :
- MMW Fortschritte der Medizin [ 1438-3276 ] ; 2003.
Descripteurs français
- KwdFr :
- MESH :
- génétique : Virus de la grippe A.
- mortalité : Grippe humaine.
- virologie : Grippe humaine.
- épidémiologie : Allemagne.
- Cause de décès, Dérive génétique, Flambées de maladies, Grippe humaine, Humains.
- Wicri :
- geographic : Allemagne.
English descriptors
- KwdEn :
- MESH :
- geographic , epidemiology : Germany.
- complications : Influenza, Human.
- genetics : Influenza A virus.
- mortality : Influenza, Human.
- virology : Influenza, Human.
- Cause of Death, Disease Outbreaks, Genetic Drift, Humans.
Abstract
In Germany, influenza lays low millions--and causes up to 15,000 deaths--every year. Three factors in particular are responsible for the severity of the disease: the cytocidal action of the virus--which, via hematogeneous spread, can involve not only the respiratory tract but also other organs such as the heart--, the immune response with fever and the production of pro-inflammatory cytokines, and bacterial superinfection of the virally predamaged respiratory mucosa. A particular threat is posed by influenza pandemics, which are usually associated with extremely high mortality and morbidity rates. The development of pandemics is furthered by the potential of the viral genome to undergo a so-called shift, as a result of which a reservoir of, for example, avian influenza A viruses can give rise to subtypes that are a danger to humans, and against which there is initially no protection. While the deaths caused by an epidemic are to be seen largely among old and multimorbid people, a pandemic also endangers the health and life of young and healthy persons.
PubMed: 12619230
Links toward previous steps (curation, corpus...)
- to stream Main, to step Corpus: Pour aller vers cette notice dans l'étape Curation :000549
Links to Exploration step
pubmed:12619230Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">[Influenza--the last big epidemic. What makes it so dangerous?].</title>
<author><name sortKey="Lange, W" sort="Lange, W" uniqKey="Lange W" first="W" last="Lange">W. Lange</name>
<affiliation wicri:level="3"><nlm:affiliation>Robert-Koch-Institut, Berlin.</nlm:affiliation>
<country>Allemagne</country>
<placeName><settlement type="city">Berlin</settlement>
<region type="land" nuts="2">Berlin</region>
</placeName>
<wicri:orgArea>Robert-Koch-Institut</wicri:orgArea>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PubMed</idno>
<date when="2003">2003</date>
<idno type="RBID">pubmed:12619230</idno>
<idno type="pmid">12619230</idno>
<idno type="wicri:Area/Main/Corpus">000549</idno>
<idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Corpus" wicri:corpus="PubMed">000549</idno>
<idno type="wicri:Area/Main/Curation">000549</idno>
<idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Curation">000549</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en">[Influenza--the last big epidemic. What makes it so dangerous?].</title>
<author><name sortKey="Lange, W" sort="Lange, W" uniqKey="Lange W" first="W" last="Lange">W. Lange</name>
<affiliation wicri:level="3"><nlm:affiliation>Robert-Koch-Institut, Berlin.</nlm:affiliation>
<country>Allemagne</country>
<placeName><settlement type="city">Berlin</settlement>
<region type="land" nuts="2">Berlin</region>
</placeName>
<wicri:orgArea>Robert-Koch-Institut</wicri:orgArea>
</affiliation>
</author>
</analytic>
<series><title level="j">MMW Fortschritte der Medizin</title>
<idno type="ISSN">1438-3276</idno>
<imprint><date when="2003" type="published">2003</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Cause of Death</term>
<term>Disease Outbreaks</term>
<term>Genetic Drift</term>
<term>Germany (epidemiology)</term>
<term>Humans</term>
<term>Influenza A virus (genetics)</term>
<term>Influenza, Human (complications)</term>
<term>Influenza, Human (mortality)</term>
<term>Influenza, Human (virology)</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Allemagne (épidémiologie)</term>
<term>Cause de décès</term>
<term>Dérive génétique</term>
<term>Flambées de maladies</term>
<term>Grippe humaine ()</term>
<term>Grippe humaine (mortalité)</term>
<term>Grippe humaine (virologie)</term>
<term>Humains</term>
<term>Virus de la grippe A (génétique)</term>
</keywords>
<keywords scheme="MESH" type="geographic" qualifier="epidemiology" xml:lang="en"><term>Germany</term>
</keywords>
<keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Influenza, Human</term>
</keywords>
<keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Influenza A virus</term>
</keywords>
<keywords scheme="MESH" qualifier="génétique" xml:lang="fr"><term>Virus de la grippe A</term>
</keywords>
<keywords scheme="MESH" qualifier="mortality" xml:lang="en"><term>Influenza, Human</term>
</keywords>
<keywords scheme="MESH" qualifier="mortalité" xml:lang="fr"><term>Grippe humaine</term>
</keywords>
<keywords scheme="MESH" qualifier="virologie" xml:lang="fr"><term>Grippe humaine</term>
</keywords>
<keywords scheme="MESH" qualifier="virology" xml:lang="en"><term>Influenza, Human</term>
</keywords>
<keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr"><term>Allemagne</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Cause of Death</term>
<term>Disease Outbreaks</term>
<term>Genetic Drift</term>
<term>Humans</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>Cause de décès</term>
<term>Dérive génétique</term>
<term>Flambées de maladies</term>
<term>Grippe humaine</term>
<term>Humains</term>
</keywords>
<keywords scheme="Wicri" type="geographic" xml:lang="fr"><term>Allemagne</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">In Germany, influenza lays low millions--and causes up to 15,000 deaths--every year. Three factors in particular are responsible for the severity of the disease: the cytocidal action of the virus--which, via hematogeneous spread, can involve not only the respiratory tract but also other organs such as the heart--, the immune response with fever and the production of pro-inflammatory cytokines, and bacterial superinfection of the virally predamaged respiratory mucosa. A particular threat is posed by influenza pandemics, which are usually associated with extremely high mortality and morbidity rates. The development of pandemics is furthered by the potential of the viral genome to undergo a so-called shift, as a result of which a reservoir of, for example, avian influenza A viruses can give rise to subtypes that are a danger to humans, and against which there is initially no protection. While the deaths caused by an epidemic are to be seen largely among old and multimorbid people, a pandemic also endangers the health and life of young and healthy persons.</div>
</front>
</TEI>
<pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">12619230</PMID>
<DateCompleted><Year>2003</Year>
<Month>05</Month>
<Day>01</Day>
</DateCompleted>
<DateRevised><Year>2006</Year>
<Month>11</Month>
<Day>15</Day>
</DateRevised>
<Article PubModel="Print"><Journal><ISSN IssnType="Print">1438-3276</ISSN>
<JournalIssue CitedMedium="Print"><Volume>145</Volume>
<Issue>3-4</Issue>
<PubDate><Year>2003</Year>
<Month>Jan</Month>
<Day>23</Day>
</PubDate>
</JournalIssue>
<Title>MMW Fortschritte der Medizin</Title>
<ISOAbbreviation>MMW Fortschr Med</ISOAbbreviation>
</Journal>
<ArticleTitle>[Influenza--the last big epidemic. What makes it so dangerous?].</ArticleTitle>
<Pagination><MedlinePgn>32-4</MedlinePgn>
</Pagination>
<Abstract><AbstractText>In Germany, influenza lays low millions--and causes up to 15,000 deaths--every year. Three factors in particular are responsible for the severity of the disease: the cytocidal action of the virus--which, via hematogeneous spread, can involve not only the respiratory tract but also other organs such as the heart--, the immune response with fever and the production of pro-inflammatory cytokines, and bacterial superinfection of the virally predamaged respiratory mucosa. A particular threat is posed by influenza pandemics, which are usually associated with extremely high mortality and morbidity rates. The development of pandemics is furthered by the potential of the viral genome to undergo a so-called shift, as a result of which a reservoir of, for example, avian influenza A viruses can give rise to subtypes that are a danger to humans, and against which there is initially no protection. While the deaths caused by an epidemic are to be seen largely among old and multimorbid people, a pandemic also endangers the health and life of young and healthy persons.</AbstractText>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Lange</LastName>
<ForeName>W</ForeName>
<Initials>W</Initials>
<AffiliationInfo><Affiliation>Robert-Koch-Institut, Berlin.</Affiliation>
</AffiliationInfo>
</Author>
</AuthorList>
<Language>ger</Language>
<PublicationTypeList><PublicationType UI="D004740">English Abstract</PublicationType>
<PublicationType UI="D016428">Journal Article</PublicationType>
</PublicationTypeList>
<VernacularTitle>Influenza--die letzte grosse Seuche. Was macht sie so bedrohlich?</VernacularTitle>
</Article>
<MedlineJournalInfo><Country>Germany</Country>
<MedlineTA>MMW Fortschr Med</MedlineTA>
<NlmUniqueID>100893959</NlmUniqueID>
<ISSNLinking>1438-3276</ISSNLinking>
</MedlineJournalInfo>
<CitationSubset>IM</CitationSubset>
<MeshHeadingList><MeshHeading><DescriptorName UI="D002423" MajorTopicYN="N">Cause of Death</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D004196" MajorTopicYN="Y">Disease Outbreaks</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D040961" MajorTopicYN="N">Genetic Drift</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D005858" MajorTopicYN="N" Type="Geographic">Germany</DescriptorName>
<QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D009980" MajorTopicYN="N">Influenza A virus</DescriptorName>
<QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D007251" MajorTopicYN="N">Influenza, Human</DescriptorName>
<QualifierName UI="Q000150" MajorTopicYN="N">complications</QualifierName>
<QualifierName UI="Q000401" MajorTopicYN="Y">mortality</QualifierName>
<QualifierName UI="Q000821" MajorTopicYN="N">virology</QualifierName>
</MeshHeading>
</MeshHeadingList>
</MedlineCitation>
<PubmedData><History><PubMedPubDate PubStatus="pubmed"><Year>2003</Year>
<Month>3</Month>
<Day>7</Day>
<Hour>4</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="medline"><Year>2003</Year>
<Month>5</Month>
<Day>2</Day>
<Hour>5</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="entrez"><Year>2003</Year>
<Month>3</Month>
<Day>7</Day>
<Hour>4</Hour>
<Minute>0</Minute>
</PubMedPubDate>
</History>
<PublicationStatus>ppublish</PublicationStatus>
<ArticleIdList><ArticleId IdType="pubmed">12619230</ArticleId>
</ArticleIdList>
</PubmedData>
</pubmed>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=ExplorPubmed/Data/Main/Curation
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000549 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Curation/biblio.hfd -nk 000549 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= *** parameter Area/wikiCode missing *** |area= ExplorPubmed |flux= Main |étape= Curation |type= RBID |clé= pubmed:12619230 |texte= [Influenza--the last big epidemic. What makes it so dangerous?]. }}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Curation/RBID.i -Sk "pubmed:12619230" \ | HfdSelect -Kh $EXPLOR_AREA/Data/Main/Curation/biblio.hfd \ | NlmPubMed2Wicri -a ExplorPubmed
This area was generated with Dilib version V0.6.35. |