Effectiveness of trivalent and monovalent influenza vaccines against laboratory-confirmed influenza infection in persons with medically attended influenza-like illness in Bavaria, Germany, 2010/2011 season.
Identifieur interne : 000215 ( Main/Curation ); précédent : 000214; suivant : 000216Effectiveness of trivalent and monovalent influenza vaccines against laboratory-confirmed influenza infection in persons with medically attended influenza-like illness in Bavaria, Germany, 2010/2011 season.
Auteurs : H. Englund [Allemagne] ; H. Campe ; W. HautmannSource :
- Epidemiology and infection [ 1469-4409 ] ; 2013.
Descripteurs français
- KwdFr :
- Adolescent, Adulte, Adulte d'âge moyen, Allemagne (épidémiologie), Enfant, Enfant d'âge préscolaire, Femelle, Grippe humaine (), Grippe humaine (épidémiologie), Humains, Jeune adulte, Mâle, Nourrisson, Nouveau-né, Pharynx (virologie), Réaction de polymérisation en chaîne, Sujet âgé, Sujet âgé de 80 ans ou plus, Vaccination (), Vaccins antigrippaux (administration et posologie), Vaccins antigrippaux (immunologie), Virus de la grippe A (isolement et purification), Virus influenza B (isolement et purification).
- MESH :
- administration et posologie : Vaccins antigrippaux.
- immunologie : Vaccins antigrippaux.
- isolement et purification : Virus de la grippe A, Virus influenza B.
- virologie : Pharynx.
- épidémiologie : Allemagne, Grippe humaine.
- Adolescent, Adulte, Adulte d'âge moyen, Enfant, Enfant d'âge préscolaire, Femelle, Grippe humaine, Humains, Jeune adulte, Mâle, Nourrisson, Nouveau-né, Réaction de polymérisation en chaîne, Sujet âgé, Sujet âgé de 80 ans ou plus, Vaccination.
- Wicri :
- geographic : Allemagne.
English descriptors
- KwdEn :
- Adolescent, Adult, Aged, Aged, 80 and over, Child, Child, Preschool, Female, Germany (epidemiology), Humans, Infant, Infant, Newborn, Influenza A virus (isolation & purification), Influenza B virus (isolation & purification), Influenza Vaccines (administration & dosage), Influenza Vaccines (immunology), Influenza, Human (epidemiology), Influenza, Human (prevention & control), Male, Middle Aged, Pharynx (virology), Polymerase Chain Reaction, Vaccination (methods), Young Adult.
- MESH :
- chemical , administration & dosage : Influenza Vaccines.
- geographic , epidemiology : Germany.
- chemical , immunology : Influenza Vaccines.
- epidemiology : Influenza, Human.
- isolation & purification : Influenza A virus, Influenza B virus.
- methods : Vaccination.
- prevention & control : Influenza, Human.
- virology : Pharynx.
- Adolescent, Adult, Aged, Aged, 80 and over, Child, Child, Preschool, Female, Humans, Infant, Infant, Newborn, Male, Middle Aged, Polymerase Chain Reaction, Young Adult.
Abstract
We estimated the vaccine effectiveness (VE) of trivalent and monovalent influenza vaccines,respectively, against laboratory-confirmed influenza infections in patients with influenza-likeillness who visited physicians participating in the Bayern Influenza Sentinel in Bavaria, Germany during 2010/2011. Swab specimens were analysed for influenza A(H1N1)pdm09, A(H3) andB by PCR. VE was estimated using the test-negative case-control study design and logistic regression. In total, 1866 patients (790 cases, 1076 controls) were included. The VE of trivalentvaccines administered in season 2010/2011 against laboratory-confirmed infection with any influenza virus, adjusted for age group, sex, chronic illness and week of arrival of the specimen,was 67.8% [95% confidence interval (CI) 39.2–82.9)]. The adjusted VE of monovalent influenza vaccines administered in season 2009/2010 against laboratory-confirmed influenza A(H1N1)pdm09 infection in 2010/2011 was 38.6% (95% CI x 70.0 to 77 . 8). This is the first VE study conducted in Bavaria. We concluded that the trivalent influenza vaccines were effective in our study population
DOI: 10.1017/S0950268812002282
PubMed: 23098364
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pubmed:23098364Le document en format XML
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<affiliation wicri:level="1"><nlm:affiliation>Bavarian Health and Food Safety Authority, Oberschleißheim, Germany. helene.englund@smi.se</nlm:affiliation>
<country xml:lang="fr">Allemagne</country>
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<author><name sortKey="Campe, H" sort="Campe, H" uniqKey="Campe H" first="H" last="Campe">H. Campe</name>
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<term>Adulte</term>
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<term>Allemagne (épidémiologie)</term>
<term>Enfant</term>
<term>Enfant d'âge préscolaire</term>
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<term>Grippe humaine ()</term>
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<term>Virus influenza B (isolement et purification)</term>
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<keywords scheme="MESH" type="chemical" qualifier="immunology" xml:lang="en"><term>Influenza Vaccines</term>
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<keywords scheme="MESH" qualifier="administration et posologie" xml:lang="fr"><term>Vaccins antigrippaux</term>
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<keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Influenza, Human</term>
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<keywords scheme="MESH" qualifier="immunologie" xml:lang="fr"><term>Vaccins antigrippaux</term>
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<term>Grippe humaine</term>
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<keywords scheme="MESH" xml:lang="en"><term>Adolescent</term>
<term>Adult</term>
<term>Aged</term>
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<term>Child</term>
<term>Child, Preschool</term>
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<keywords scheme="MESH" xml:lang="fr"><term>Adolescent</term>
<term>Adulte</term>
<term>Adulte d'âge moyen</term>
<term>Enfant</term>
<term>Enfant d'âge préscolaire</term>
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<term>Grippe humaine</term>
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<term>Réaction de polymérisation en chaîne</term>
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<term>Sujet âgé de 80 ans ou plus</term>
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<front><div type="abstract" xml:lang="en">We estimated the vaccine effectiveness (VE) of trivalent and monovalent influenza vaccines,respectively, against laboratory-confirmed influenza infections in patients with influenza-likeillness who visited physicians participating in the Bayern Influenza Sentinel in Bavaria, Germany during 2010/2011. Swab specimens were analysed for influenza A(H1N1)pdm09, A(H3) andB by PCR. VE was estimated using the test-negative case-control study design and logistic regression. In total, 1866 patients (790 cases, 1076 controls) were included. The VE of trivalentvaccines administered in season 2010/2011 against laboratory-confirmed infection with any influenza virus, adjusted for age group, sex, chronic illness and week of arrival of the specimen,was 67.8% [95% confidence interval (CI) 39.2–82.9)]. The adjusted VE of monovalent influenza vaccines administered in season 2009/2010 against laboratory-confirmed influenza A(H1N1)pdm09 infection in 2010/2011 was 38.6% (95% CI x 70.0 to 77 . 8). This is the first VE study conducted in Bavaria. We concluded that the trivalent influenza vaccines were effective in our study population</div>
</front>
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<Abstract><AbstractText>We estimated the vaccine effectiveness (VE) of trivalent and monovalent influenza vaccines,respectively, against laboratory-confirmed influenza infections in patients with influenza-likeillness who visited physicians participating in the Bayern Influenza Sentinel in Bavaria, Germany during 2010/2011. Swab specimens were analysed for influenza A(H1N1)pdm09, A(H3) andB by PCR. VE was estimated using the test-negative case-control study design and logistic regression. In total, 1866 patients (790 cases, 1076 controls) were included. The VE of trivalentvaccines administered in season 2010/2011 against laboratory-confirmed infection with any influenza virus, adjusted for age group, sex, chronic illness and week of arrival of the specimen,was 67.8% [95% confidence interval (CI) 39.2–82.9)]. The adjusted VE of monovalent influenza vaccines administered in season 2009/2010 against laboratory-confirmed influenza A(H1N1)pdm09 infection in 2010/2011 was 38.6% (95% CI x 70.0 to 77 . 8). This is the first VE study conducted in Bavaria. We concluded that the trivalent influenza vaccines were effective in our study population</AbstractText>
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