Clinical symptoms cannot predict influenza infection during the 2013 influenza season in Bavaria, Germany.
Identifieur interne : 000111 ( Main/Curation ); précédent : 000110; suivant : 000112Clinical symptoms cannot predict influenza infection during the 2013 influenza season in Bavaria, Germany.
Auteurs : H. Campe [Allemagne] ; S. Heinzinger [Allemagne] ; C. Hartberger [Allemagne] ; A. Sing [Allemagne]Source :
- Epidemiology and infection [ 1469-4409 ] ; 2016.
Descripteurs français
- KwdFr :
- Adolescent, Adulte, Adulte d'âge moyen, Allemagne (épidémiologie), Enfant, Enfant d'âge préscolaire, Grippe humaine (diagnostic), Grippe humaine (virologie), Grippe humaine (épidémiologie), Humains, Infections de l'appareil respiratoire (diagnostic), Infections de l'appareil respiratoire (virologie), Infections de l'appareil respiratoire (épidémiologie), Jeune adulte, Maladie aigüe, Maladies virales (diagnostic), Maladies virales (virologie), Maladies virales (épidémiologie), Nourrisson, Nouveau-né, Saisons, Sujet âgé, Sujet âgé de 80 ans ou plus.
- MESH :
- diagnostic : Grippe humaine, Infections de l'appareil respiratoire, Maladies virales.
- virologie : Grippe humaine, Infections de l'appareil respiratoire, Maladies virales.
- épidémiologie : Allemagne, Grippe humaine, Infections de l'appareil respiratoire, Maladies virales.
- Adolescent, Adulte, Adulte d'âge moyen, Enfant, Enfant d'âge préscolaire, Humains, Jeune adulte, Maladie aigüe, Nourrisson, Nouveau-né, Saisons, Sujet âgé, Sujet âgé de 80 ans ou plus.
- Wicri :
- geographic : Allemagne.
English descriptors
- KwdEn :
- Acute Disease, Adolescent, Adult, Aged, Aged, 80 and over, Child, Child, Preschool, Germany (epidemiology), Humans, Infant, Infant, Newborn, Influenza, Human (diagnosis), Influenza, Human (epidemiology), Influenza, Human (virology), Middle Aged, Respiratory Tract Infections (diagnosis), Respiratory Tract Infections (epidemiology), Respiratory Tract Infections (virology), Seasons, Virus Diseases (diagnosis), Virus Diseases (epidemiology), Virus Diseases (virology), Young Adult.
- MESH :
- geographic , epidemiology : Germany.
- diagnosis : Influenza, Human, Respiratory Tract Infections, Virus Diseases.
- epidemiology : Influenza, Human, Respiratory Tract Infections, Virus Diseases.
- virology : Influenza, Human, Respiratory Tract Infections, Virus Diseases.
- Acute Disease, Adolescent, Adult, Aged, Aged, 80 and over, Child, Child, Preschool, Humans, Infant, Infant, Newborn, Middle Aged, Seasons, Young Adult.
Abstract
For influenza surveillance and diagnosis typical clinical symptoms are traditionally used to discriminate influenza virus infections from infections by other pathogens. During the 2013 influenza season we performed a multiplex assay for 16 different viruses in 665 swabs from patients with acute respiratory infections (ARIs) to display the variety of different pathogens causing ARI and to test the diagnostic value of both the commonly used case definitions [ARI, and influenza like illness (ILI)] as well as the clinical judgement of physicians, respectively, to achieve a laboratory-confirmed influenza diagnosis. Fourteen different viruses were identified as causing ARI/ILI. Influenza diagnosis based on clinical signs overestimated the number of laboratory-confirmed influenza cases and misclassified cases. Furthermore, ILI case definition and physicians agreed in only 287/651 (44%) cases with laboratory confirmation. Influenza case management has to be supported by laboratory confirmation to allow evidence-based decisions. Epidemiological syndromic surveillance data should be supported by laboratory confirmation for reasonable interpretation.
DOI: 10.1017/S0950268815002228
PubMed: 26388141
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pubmed:26388141Le document en format XML
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<term>Enfant d'âge préscolaire</term>
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<term>Saisons</term>
<term>Sujet âgé</term>
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<front><div type="abstract" xml:lang="en">For influenza surveillance and diagnosis typical clinical symptoms are traditionally used to discriminate influenza virus infections from infections by other pathogens. During the 2013 influenza season we performed a multiplex assay for 16 different viruses in 665 swabs from patients with acute respiratory infections (ARIs) to display the variety of different pathogens causing ARI and to test the diagnostic value of both the commonly used case definitions [ARI, and influenza like illness (ILI)] as well as the clinical judgement of physicians, respectively, to achieve a laboratory-confirmed influenza diagnosis. Fourteen different viruses were identified as causing ARI/ILI. Influenza diagnosis based on clinical signs overestimated the number of laboratory-confirmed influenza cases and misclassified cases. Furthermore, ILI case definition and physicians agreed in only 287/651 (44%) cases with laboratory confirmation. Influenza case management has to be supported by laboratory confirmation to allow evidence-based decisions. Epidemiological syndromic surveillance data should be supported by laboratory confirmation for reasonable interpretation. </div>
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<Abstract><AbstractText>For influenza surveillance and diagnosis typical clinical symptoms are traditionally used to discriminate influenza virus infections from infections by other pathogens. During the 2013 influenza season we performed a multiplex assay for 16 different viruses in 665 swabs from patients with acute respiratory infections (ARIs) to display the variety of different pathogens causing ARI and to test the diagnostic value of both the commonly used case definitions [ARI, and influenza like illness (ILI)] as well as the clinical judgement of physicians, respectively, to achieve a laboratory-confirmed influenza diagnosis. Fourteen different viruses were identified as causing ARI/ILI. Influenza diagnosis based on clinical signs overestimated the number of laboratory-confirmed influenza cases and misclassified cases. Furthermore, ILI case definition and physicians agreed in only 287/651 (44%) cases with laboratory confirmation. Influenza case management has to be supported by laboratory confirmation to allow evidence-based decisions. Epidemiological syndromic surveillance data should be supported by laboratory confirmation for reasonable interpretation. </AbstractText>
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