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[Severe upper abdominal pain during a long distance flight].

Identifieur interne : 000149 ( Main/Corpus ); précédent : 000148; suivant : 000150

[Severe upper abdominal pain during a long distance flight].

Auteurs : D. Bestehorn ; C. Schmidt ; G. Lock

Source :

RBID : pubmed:25254402

English descriptors

Abstract

A 43-year-old woman of Ghanaian origin presented with severe upper abdominal pain starting on a long distance flight. Physical examination revealed tenderness on palpation in the left upper abdomen and flank. There was no report of pre-existing conditions or permanent medication in the medical history.

DOI: 10.1055/s-0034-1370287
PubMed: 25254402

Links to Exploration step

pubmed:25254402

Le document en format XML

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<title xml:lang="en">[Severe upper abdominal pain during a long distance flight].</title>
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<name sortKey="Bestehorn, D" sort="Bestehorn, D" uniqKey="Bestehorn D" first="D" last="Bestehorn">D. Bestehorn</name>
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<nlm:affiliation>Klinik für Innere Medizin, Albertinen-Krankenhaus, Hamburg.</nlm:affiliation>
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<name sortKey="Schmidt, C" sort="Schmidt, C" uniqKey="Schmidt C" first="C" last="Schmidt">C. Schmidt</name>
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<nlm:affiliation>Klinik für Innere Medizin, Albertinen-Krankenhaus, Hamburg.</nlm:affiliation>
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<name sortKey="Lock, G" sort="Lock, G" uniqKey="Lock G" first="G" last="Lock">G. Lock</name>
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<nlm:affiliation>Klinik für Innere Medizin, Albertinen-Krankenhaus, Hamburg.</nlm:affiliation>
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<name sortKey="Schmidt, C" sort="Schmidt, C" uniqKey="Schmidt C" first="C" last="Schmidt">C. Schmidt</name>
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<title level="j">Deutsche medizinische Wochenschrift (1946)</title>
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<term>Abdomen, Acute (etiology)</term>
<term>Abdomen, Acute (therapy)</term>
<term>Adult</term>
<term>Air Travel</term>
<term>Anemia, Sickle Cell (diagnosis)</term>
<term>Diagnosis, Differential</term>
<term>Female</term>
<term>Genetic Carrier Screening</term>
<term>Germany</term>
<term>Ghana (ethnology)</term>
<term>Humans</term>
<term>Medical History Taking</term>
<term>Splenic Infarction (diagnosis)</term>
<term>Ultrasonography</term>
<term>alpha-Thalassemia (diagnosis)</term>
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<term>Anemia, Sickle Cell</term>
<term>Splenic Infarction</term>
<term>alpha-Thalassemia</term>
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<keywords scheme="MESH" qualifier="ethnology" xml:lang="en">
<term>Ghana</term>
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<term>Abdomen, Acute</term>
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<term>Abdomen, Acute</term>
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<keywords scheme="MESH" xml:lang="en">
<term>Adult</term>
<term>Air Travel</term>
<term>Diagnosis, Differential</term>
<term>Female</term>
<term>Genetic Carrier Screening</term>
<term>Germany</term>
<term>Humans</term>
<term>Medical History Taking</term>
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<div type="abstract" xml:lang="en">A 43-year-old woman of Ghanaian origin presented with severe upper abdominal pain starting on a long distance flight. Physical examination revealed tenderness on palpation in the left upper abdomen and flank. There was no report of pre-existing conditions or permanent medication in the medical history.</div>
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<DateCompleted>
<Year>2014</Year>
<Month>11</Month>
<Day>21</Day>
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<DateRevised>
<Year>2017</Year>
<Month>11</Month>
<Day>16</Day>
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<ISSN IssnType="Electronic">1439-4413</ISSN>
<JournalIssue CitedMedium="Internet">
<Volume>139</Volume>
<Issue>40</Issue>
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<Year>2014</Year>
<Month>Oct</Month>
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<Title>Deutsche medizinische Wochenschrift (1946)</Title>
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<ArticleTitle>[Severe upper abdominal pain during a long distance flight].</ArticleTitle>
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<ELocationID EIdType="doi" ValidYN="Y">10.1055/s-0034-1370287</ELocationID>
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<AbstractText Label="HISTORY AND CLINICAL FINDINGS" NlmCategory="METHODS">A 43-year-old woman of Ghanaian origin presented with severe upper abdominal pain starting on a long distance flight. Physical examination revealed tenderness on palpation in the left upper abdomen and flank. There was no report of pre-existing conditions or permanent medication in the medical history.</AbstractText>
<AbstractText Label="INVESTIGATIONS AND DIAGNOSIS" NlmCategory="METHODS">Laboratory tests showed signs of haemolytic anemia and elevated inflammatory parameters. The "thick blood smear" was normal. Ultrasonography revealed an enlarged spleen (14×5 cm) with inhomogeneous parenchyma and vast, diffusely spread hypoechoic lesions in perihilar location, interpreted as extended splenic infarction. Symptom onset on a long distance flight, haemolytic anemia and extended splenic infarction led to the assumption of a vasoocclusive crisis with haemolysis. Moleculargenetic tests proved the presence of HbSC-sickle cell disease and heterozygous alpha-thalassemia.</AbstractText>
<AbstractText Label="TREATMENT AND COURSE" NlmCategory="METHODS">After infusion of crystalloid solution the patient was asymptomatic further on. Due to splenic infarction she received prophylactic treatment with Cefuroxim. A vaccination against pneumococci, meningococci and Haemophilus influenza B was recommended.</AbstractText>
<AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">Mild hypoxia and dehydration on a long distance flight can trigger a sickle cell crisis and may contribute to late clinical manifestation and diagnosis of sickle cell disease in some cases. Patients suffering from HbSC-sickle cell disease are at risk for the same life-threatening complications as patients with HbSS-sickle cell disease. HbSC-sickle cell disease should not be considered as a mild form of HbSS-sickle cell disease but as a separate disease with specific clinical manifestations. In contrast-enhanced ultrasonography, splenic infarction due to sickle cell crisis may markedly differ from "typical" arterial thromboembolic infarction.</AbstractText>
<CopyrightInformation>© Georg Thieme Verlag KG Stuttgart · New York.</CopyrightInformation>
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<VernacularTitle>Heftige Oberbauchbeschwerden während eines Langstreckenfluges.</VernacularTitle>
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