Dental endosseous implant assessments in a type 2 diabetic population: a prospective study.
Identifieur interne : 003615 ( PubMed/Curation ); précédent : 003614; suivant : 003616Dental endosseous implant assessments in a type 2 diabetic population: a prospective study.
Auteurs : J W Olson [États-Unis] ; A F Shernoff ; J L Tarlow ; J A Colwell ; J P Scheetz ; S F BinghamSource :
- The International journal of oral & maxillofacial implants [ 0882-2786 ]
Descripteurs français
- KwdFr :
- Adulte, Adulte d'âge moyen, Analyse de régression, Cicatrisation de plaie, Conception de prothèse dentaire, Diabète de type 2 (), Diabète de type 2 (physiopathologie), Diabète de type 2 (sang), Facteurs de l'âge, Facteurs temps, Glycémie (analyse), Humains, Implants dentaires, Mandibule (), Mâchoire édentée (), Mâchoire édentée (rééducation et réadaptation), Mâle, Ostéo-intégration, Overdenture, Pose d'implant dentaire endo-osseux, Prothèse dentaire implanto-portée, Résultat thérapeutique, Sujet âgé, Tabagisme (physiopathologie), Échec de restauration dentaire, Études de suivi, Études prospectives.
- MESH :
- analyse : Glycémie.
- physiopathologie : Diabète de type 2, Tabagisme.
- rééducation et réadaptation : Mâchoire édentée.
- sang : Diabète de type 2.
- Adulte, Adulte d'âge moyen, Analyse de régression, Cicatrisation de plaie, Conception de prothèse dentaire, Diabète de type 2, Facteurs de l'âge, Facteurs temps, Humains, Implants dentaires, Mandibule, Mâchoire édentée, Mâle, Ostéo-intégration, Overdenture, Pose d'implant dentaire endo-osseux, Prothèse dentaire implanto-portée, Résultat thérapeutique, Sujet âgé, Échec de restauration dentaire, Études de suivi, Études prospectives.
English descriptors
- KwdEn :
- Adult, Age Factors, Aged, Blood Glucose (analysis), Dental Implantation, Endosseous, Dental Implants, Dental Prosthesis Design, Dental Prosthesis, Implant-Supported, Dental Restoration Failure, Denture, Overlay, Diabetes Mellitus, Type 2 (blood), Diabetes Mellitus, Type 2 (physiopathology), Diabetes Mellitus, Type 2 (prevention & control), Follow-Up Studies, Glycated Hemoglobin A (analysis), Humans, Jaw, Edentulous (rehabilitation), Jaw, Edentulous (surgery), Male, Mandible (surgery), Middle Aged, Osseointegration, Prospective Studies, Regression Analysis, Smoking (physiopathology), Time Factors, Treatment Outcome, Wound Healing.
- MESH :
- chemical , analysis : Blood Glucose, Glycated Hemoglobin A.
- blood : Diabetes Mellitus, Type 2.
- physiopathology : Diabetes Mellitus, Type 2, Smoking.
- prevention & control : Diabetes Mellitus, Type 2.
- rehabilitation : Jaw, Edentulous.
- surgery : Jaw, Edentulous, Mandible.
- Adult, Age Factors, Aged, Dental Implantation, Endosseous, Dental Implants, Dental Prosthesis Design, Dental Prosthesis, Implant-Supported, Dental Restoration Failure, Denture, Overlay, Follow-Up Studies, Humans, Male, Middle Aged, Osseointegration, Prospective Studies, Regression Analysis, Time Factors, Treatment Outcome, Wound Healing.
Abstract
Diabetes mellitus, a prevalent disorder worldwide, is associated with systemic adverse sequelae, such as wound healing alterations, which may affect osseointegration of dental implants. This prospective multicenter study assessed the success of 2-stage endosseous root-form implants (3 different implant systems) placed in the mandibular symphysis of 89 male type 2 diabetic subjects. The implants were uncovered approximately 4 months after placement, restored with an implant-supported, Hader bar clip-retained overdenture, and maintained at scheduled follow-up data collection examinations for 60 months after loading. Sixteen (9.0%) of the 178 implants failed. Life table methods calculated implant survival at approximately 88%, from prosthesis placement through the 60-month follow-up, and at approximately 90% from implant placement through the observation period. No implants failed between surgical placement and uncovering, 5 failed at uncovering, 7 failed after uncovering before prosthesis placement, and 4 failed after prosthesis placement. Fasting plasma glucose (FPG) and glycosylated hemoglobin (HbA1c) values were determined before implant placement (baseline) and approximately 4 months later at surgical uncovering (follow-up). The 5-year implant outcomes (successes versus failures) were analyzed against the following predictor variables: (1) baseline and follow-up FPG values, (2) baseline and follow-up HbA1c values, (3) subject age, (4) duration of diabetes (years), (5) baseline diabetic therapy, (6) smoking history, and (7) implant length. Regression analysis found only duration of diabetes (P < .025) and implant length (P < .001) to be statistically significant predictors of implant failure. There was no statistically significant difference in failure rates between the 3 different implant systems used. This study supports the use of dental implants in type 2 diabetic patients.
PubMed: 11151579
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pubmed:11151579Le document en format XML
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<term>Dental Implants</term>
<term>Dental Prosthesis Design</term>
<term>Dental Prosthesis, Implant-Supported</term>
<term>Dental Restoration Failure</term>
<term>Denture, Overlay</term>
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<term>Diabetes Mellitus, Type 2 (physiopathology)</term>
<term>Diabetes Mellitus, Type 2 (prevention & control)</term>
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<term>Prospective Studies</term>
<term>Regression Analysis</term>
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<term>Time Factors</term>
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<term>Adulte d'âge moyen</term>
<term>Analyse de régression</term>
<term>Cicatrisation de plaie</term>
<term>Conception de prothèse dentaire</term>
<term>Diabète de type 2 ()</term>
<term>Diabète de type 2 (physiopathologie)</term>
<term>Diabète de type 2 (sang)</term>
<term>Facteurs de l'âge</term>
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<term>Smoking</term>
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<term>Age Factors</term>
<term>Aged</term>
<term>Dental Implantation, Endosseous</term>
<term>Dental Implants</term>
<term>Dental Prosthesis Design</term>
<term>Dental Prosthesis, Implant-Supported</term>
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<term>Denture, Overlay</term>
<term>Follow-Up Studies</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Osseointegration</term>
<term>Prospective Studies</term>
<term>Regression Analysis</term>
<term>Time Factors</term>
<term>Treatment Outcome</term>
<term>Wound Healing</term>
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<term>Adulte d'âge moyen</term>
<term>Analyse de régression</term>
<term>Cicatrisation de plaie</term>
<term>Conception de prothèse dentaire</term>
<term>Diabète de type 2</term>
<term>Facteurs de l'âge</term>
<term>Facteurs temps</term>
<term>Humains</term>
<term>Implants dentaires</term>
<term>Mandibule</term>
<term>Mâchoire édentée</term>
<term>Mâle</term>
<term>Ostéo-intégration</term>
<term>Overdenture</term>
<term>Pose d'implant dentaire endo-osseux</term>
<term>Prothèse dentaire implanto-portée</term>
<term>Résultat thérapeutique</term>
<term>Sujet âgé</term>
<term>Échec de restauration dentaire</term>
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<front><div type="abstract" xml:lang="en">Diabetes mellitus, a prevalent disorder worldwide, is associated with systemic adverse sequelae, such as wound healing alterations, which may affect osseointegration of dental implants. This prospective multicenter study assessed the success of 2-stage endosseous root-form implants (3 different implant systems) placed in the mandibular symphysis of 89 male type 2 diabetic subjects. The implants were uncovered approximately 4 months after placement, restored with an implant-supported, Hader bar clip-retained overdenture, and maintained at scheduled follow-up data collection examinations for 60 months after loading. Sixteen (9.0%) of the 178 implants failed. Life table methods calculated implant survival at approximately 88%, from prosthesis placement through the 60-month follow-up, and at approximately 90% from implant placement through the observation period. No implants failed between surgical placement and uncovering, 5 failed at uncovering, 7 failed after uncovering before prosthesis placement, and 4 failed after prosthesis placement. Fasting plasma glucose (FPG) and glycosylated hemoglobin (HbA1c) values were determined before implant placement (baseline) and approximately 4 months later at surgical uncovering (follow-up). The 5-year implant outcomes (successes versus failures) were analyzed against the following predictor variables: (1) baseline and follow-up FPG values, (2) baseline and follow-up HbA1c values, (3) subject age, (4) duration of diabetes (years), (5) baseline diabetic therapy, (6) smoking history, and (7) implant length. Regression analysis found only duration of diabetes (P < .025) and implant length (P < .001) to be statistically significant predictors of implant failure. There was no statistically significant difference in failure rates between the 3 different implant systems used. This study supports the use of dental implants in type 2 diabetic patients.</div>
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<ArticleTitle>Dental endosseous implant assessments in a type 2 diabetic population: a prospective study.</ArticleTitle>
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<Abstract><AbstractText>Diabetes mellitus, a prevalent disorder worldwide, is associated with systemic adverse sequelae, such as wound healing alterations, which may affect osseointegration of dental implants. This prospective multicenter study assessed the success of 2-stage endosseous root-form implants (3 different implant systems) placed in the mandibular symphysis of 89 male type 2 diabetic subjects. The implants were uncovered approximately 4 months after placement, restored with an implant-supported, Hader bar clip-retained overdenture, and maintained at scheduled follow-up data collection examinations for 60 months after loading. Sixteen (9.0%) of the 178 implants failed. Life table methods calculated implant survival at approximately 88%, from prosthesis placement through the 60-month follow-up, and at approximately 90% from implant placement through the observation period. No implants failed between surgical placement and uncovering, 5 failed at uncovering, 7 failed after uncovering before prosthesis placement, and 4 failed after prosthesis placement. Fasting plasma glucose (FPG) and glycosylated hemoglobin (HbA1c) values were determined before implant placement (baseline) and approximately 4 months later at surgical uncovering (follow-up). The 5-year implant outcomes (successes versus failures) were analyzed against the following predictor variables: (1) baseline and follow-up FPG values, (2) baseline and follow-up HbA1c values, (3) subject age, (4) duration of diabetes (years), (5) baseline diabetic therapy, (6) smoking history, and (7) implant length. Regression analysis found only duration of diabetes (P < .025) and implant length (P < .001) to be statistically significant predictors of implant failure. There was no statistically significant difference in failure rates between the 3 different implant systems used. This study supports the use of dental implants in type 2 diabetic patients.</AbstractText>
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