Serveur d'exploration sur le patient édenté

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Tooth loss, pancreatic cancer, and Helicobacter pylori.

Identifieur interne : 002E71 ( PubMed/Curation ); précédent : 002E70; suivant : 002E72

Tooth loss, pancreatic cancer, and Helicobacter pylori.

Auteurs : Rachael Z. Stolzenberg-Solomon [États-Unis] ; Kevin W. Dodd ; Martin J. Blaser ; Jarmo Virtamo ; Philip R. Taylor ; Demetrius Albanes

Source :

RBID : pubmed:12816788

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English descriptors

Abstract

Poor dental health has been associated with increased risks of oral, esophageal, and gastric cancer and may also be associated with pancreatic cancer. In addition, Helicobacter pylori has been found in dental plaque and has been associated with periodontal disease and pancreatic cancer.

PubMed: 12816788

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pubmed:12816788

Le document en format XML

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<title xml:lang="en">Tooth loss, pancreatic cancer, and Helicobacter pylori.</title>
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<name sortKey="Stolzenberg Solomon, Rachael Z" sort="Stolzenberg Solomon, Rachael Z" uniqKey="Stolzenberg Solomon R" first="Rachael Z" last="Stolzenberg-Solomon">Rachael Z. Stolzenberg-Solomon</name>
<affiliation wicri:level="1">
<nlm:affiliation>Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA. rs221z@nih.gov</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892</wicri:regionArea>
</affiliation>
</author>
<author>
<name sortKey="Dodd, Kevin W" sort="Dodd, Kevin W" uniqKey="Dodd K" first="Kevin W" last="Dodd">Kevin W. Dodd</name>
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<name sortKey="Blaser, Martin J" sort="Blaser, Martin J" uniqKey="Blaser M" first="Martin J" last="Blaser">Martin J. Blaser</name>
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<name sortKey="Virtamo, Jarmo" sort="Virtamo, Jarmo" uniqKey="Virtamo J" first="Jarmo" last="Virtamo">Jarmo Virtamo</name>
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<author>
<name sortKey="Taylor, Philip R" sort="Taylor, Philip R" uniqKey="Taylor P" first="Philip R" last="Taylor">Philip R. Taylor</name>
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<name sortKey="Albanes, Demetrius" sort="Albanes, Demetrius" uniqKey="Albanes D" first="Demetrius" last="Albanes">Demetrius Albanes</name>
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<title xml:lang="en">Tooth loss, pancreatic cancer, and Helicobacter pylori.</title>
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<name sortKey="Stolzenberg Solomon, Rachael Z" sort="Stolzenberg Solomon, Rachael Z" uniqKey="Stolzenberg Solomon R" first="Rachael Z" last="Stolzenberg-Solomon">Rachael Z. Stolzenberg-Solomon</name>
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<name sortKey="Dodd, Kevin W" sort="Dodd, Kevin W" uniqKey="Dodd K" first="Kevin W" last="Dodd">Kevin W. Dodd</name>
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<name sortKey="Blaser, Martin J" sort="Blaser, Martin J" uniqKey="Blaser M" first="Martin J" last="Blaser">Martin J. Blaser</name>
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<title level="j">The American journal of clinical nutrition</title>
<idno type="ISSN">0002-9165</idno>
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<date when="2003" type="published">2003</date>
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<term>Aged</term>
<term>Antibodies, Bacterial (analysis)</term>
<term>Helicobacter pylori (immunology)</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Mouth, Edentulous (complications)</term>
<term>Mouth, Edentulous (immunology)</term>
<term>Odds Ratio</term>
<term>Pancreatic Neoplasms (complications)</term>
<term>Proportional Hazards Models</term>
<term>Tooth Loss (complications)</term>
<term>Tooth Loss (immunology)</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr">
<term>Adulte d'âge moyen</term>
<term>Anticorps antibactériens (analyse)</term>
<term>Bouche édentée ()</term>
<term>Bouche édentée (immunologie)</term>
<term>Helicobacter pylori (immunologie)</term>
<term>Humains</term>
<term>Modèles de hasards proportionnels</term>
<term>Mâle</term>
<term>Odds ratio</term>
<term>Perte dentaire ()</term>
<term>Perte dentaire (immunologie)</term>
<term>Sujet âgé</term>
<term>Tumeurs du pancréas ()</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="analysis" xml:lang="en">
<term>Antibodies, Bacterial</term>
</keywords>
<keywords scheme="MESH" qualifier="analyse" xml:lang="fr">
<term>Anticorps antibactériens</term>
</keywords>
<keywords scheme="MESH" qualifier="complications" xml:lang="en">
<term>Mouth, Edentulous</term>
<term>Pancreatic Neoplasms</term>
<term>Tooth Loss</term>
</keywords>
<keywords scheme="MESH" qualifier="immunologie" xml:lang="fr">
<term>Bouche édentée</term>
<term>Helicobacter pylori</term>
<term>Perte dentaire</term>
</keywords>
<keywords scheme="MESH" qualifier="immunology" xml:lang="en">
<term>Helicobacter pylori</term>
<term>Mouth, Edentulous</term>
<term>Tooth Loss</term>
</keywords>
<keywords scheme="MESH" xml:lang="en">
<term>Aged</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Odds Ratio</term>
<term>Proportional Hazards Models</term>
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<term>Bouche édentée</term>
<term>Humains</term>
<term>Modèles de hasards proportionnels</term>
<term>Mâle</term>
<term>Odds ratio</term>
<term>Perte dentaire</term>
<term>Sujet âgé</term>
<term>Tumeurs du pancréas</term>
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<front>
<div type="abstract" xml:lang="en">Poor dental health has been associated with increased risks of oral, esophageal, and gastric cancer and may also be associated with pancreatic cancer. In addition, Helicobacter pylori has been found in dental plaque and has been associated with periodontal disease and pancreatic cancer.</div>
</front>
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<pubmed>
<MedlineCitation Status="MEDLINE" Owner="NLM">
<PMID Version="1">12816788</PMID>
<DateCompleted>
<Year>2003</Year>
<Month>07</Month>
<Day>08</Day>
</DateCompleted>
<DateRevised>
<Year>2007</Year>
<Month>11</Month>
<Day>14</Day>
</DateRevised>
<Article PubModel="Print">
<Journal>
<ISSN IssnType="Print">0002-9165</ISSN>
<JournalIssue CitedMedium="Print">
<Volume>78</Volume>
<Issue>1</Issue>
<PubDate>
<Year>2003</Year>
<Month>Jul</Month>
</PubDate>
</JournalIssue>
<Title>The American journal of clinical nutrition</Title>
<ISOAbbreviation>Am. J. Clin. Nutr.</ISOAbbreviation>
</Journal>
<ArticleTitle>Tooth loss, pancreatic cancer, and Helicobacter pylori.</ArticleTitle>
<Pagination>
<MedlinePgn>176-81</MedlinePgn>
</Pagination>
<Abstract>
<AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">Poor dental health has been associated with increased risks of oral, esophageal, and gastric cancer and may also be associated with pancreatic cancer. In addition, Helicobacter pylori has been found in dental plaque and has been associated with periodontal disease and pancreatic cancer.</AbstractText>
<AbstractText Label="OBJECTIVE" NlmCategory="OBJECTIVE">The objective was to investigate prospectively the relation between dentition history and pancreatic cancer in the Alpha-Tocopherol, Beta-Carotene Cancer Prevention Study cohort in Finland and the association between dentition history and H. pylori seropositivity in a cross-sectional sample of subjects without cancer (n = 475) from the same cohort.</AbstractText>
<AbstractText Label="DESIGN" NlmCategory="METHODS">Of the 29,104 male smokers aged 50-69 y in the cohort for whom there were complete data, 174 developed pancreatic cancer from 1985 to 1997. Cox proportional hazard models were used to estimate age-, smoking-, education-, urban living-, and height-adjusted hazard ratios and 95% CIs for pancreatic cancer, and logistic regression models were used to estimate age- and education-adjusted odds ratios for H. pylori carriage.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">Tooth loss was positively associated with pancreatic cancer (edentulous compared with missing 0-10 teeth: hazard ratio = 1.63; 95% CI: 1.09, 2.46; P for trend = 0.02) but was not significantly associated with H. pylori seropositivity (edentulous compared with missing 0-10 teeth: odds ratio = 1.30; 95% CI: 0.73, 2.32; P for trend = 0.37).</AbstractText>
<AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">Additional studies are needed to evaluate the association between tooth loss and pancreatic cancer, as well as cancers at other gastrointestinal sites, particularly with respect to possible biological mechanisms.</AbstractText>
</Abstract>
<AuthorList CompleteYN="Y">
<Author ValidYN="Y">
<LastName>Stolzenberg-Solomon</LastName>
<ForeName>Rachael Z</ForeName>
<Initials>RZ</Initials>
<AffiliationInfo>
<Affiliation>Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA. rs221z@nih.gov</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Dodd</LastName>
<ForeName>Kevin W</ForeName>
<Initials>KW</Initials>
</Author>
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<LastName>Blaser</LastName>
<ForeName>Martin J</ForeName>
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<ForeName>Jarmo</ForeName>
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<ForeName>Philip R</ForeName>
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<ForeName>Demetrius</ForeName>
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<Language>eng</Language>
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<GrantID>N01CN45035</GrantID>
<Acronym>CN</Acronym>
<Agency>NCI NIH HHS</Agency>
<Country>United States</Country>
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<Acronym>CN</Acronym>
<Agency>NCI NIH HHS</Agency>
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<MeshHeading>
<DescriptorName UI="D000368" MajorTopicYN="N">Aged</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D000907" MajorTopicYN="N">Antibodies, Bacterial</DescriptorName>
<QualifierName UI="Q000032" MajorTopicYN="Y">analysis</QualifierName>
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<DescriptorName UI="D016480" MajorTopicYN="N">Helicobacter pylori</DescriptorName>
<QualifierName UI="Q000276" MajorTopicYN="Y">immunology</QualifierName>
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<MeshHeading>
<DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName>
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<DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName>
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<DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName>
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<DescriptorName UI="D009066" MajorTopicYN="N">Mouth, Edentulous</DescriptorName>
<QualifierName UI="Q000150" MajorTopicYN="N">complications</QualifierName>
<QualifierName UI="Q000276" MajorTopicYN="N">immunology</QualifierName>
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<MeshHeading>
<DescriptorName UI="D016017" MajorTopicYN="N">Odds Ratio</DescriptorName>
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<MeshHeading>
<DescriptorName UI="D010190" MajorTopicYN="N">Pancreatic Neoplasms</DescriptorName>
<QualifierName UI="Q000150" MajorTopicYN="Y">complications</QualifierName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D016016" MajorTopicYN="N">Proportional Hazards Models</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D016388" MajorTopicYN="N">Tooth Loss</DescriptorName>
<QualifierName UI="Q000150" MajorTopicYN="Y">complications</QualifierName>
<QualifierName UI="Q000276" MajorTopicYN="Y">immunology</QualifierName>
</MeshHeading>
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</MedlineCitation>
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<Year>2003</Year>
<Month>6</Month>
<Day>21</Day>
<Hour>5</Hour>
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