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Guided bone regeneration with autogenous block grafts applied to Le Fort I osteotomy for treatment of severely resorbed maxillae: a 4- to 6-year prospective study.

Identifieur interne : 001302 ( PubMed/Curation ); précédent : 001301; suivant : 001303

Guided bone regeneration with autogenous block grafts applied to Le Fort I osteotomy for treatment of severely resorbed maxillae: a 4- to 6-year prospective study.

Auteurs : Daniele De Santis [Italie] ; Lorenzo Trevisiol ; Antonio D'Agostino ; Alessandro Cucchi ; Antonio De Gemmis ; Pier Francesco Nocini

Source :

RBID : pubmed:21504483

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English descriptors

Abstract

Edentulism causes progressive bone resorption of the maxillae, which can lead to altered maxillo-mandibular relationships. The aim of the study was to evaluate the applicability of guided bone regeneration (GBR) to Le Fort I osteotomies with interpositional bone grafts for treatment of patients with severe maxillary atrophy.

DOI: 10.1111/j.1600-0501.2011.02181.x
PubMed: 21504483

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pubmed:21504483

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<title xml:lang="en">Guided bone regeneration with autogenous block grafts applied to Le Fort I osteotomy for treatment of severely resorbed maxillae: a 4- to 6-year prospective study.</title>
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<name sortKey="De Santis, Daniele" sort="De Santis, Daniele" uniqKey="De Santis D" first="Daniele" last="De Santis">Daniele De Santis</name>
<affiliation wicri:level="1">
<nlm:affiliation>Department of Morphological and Biomedical Sciences, Section of Dentistry and Maxillofacial Surgery, University of Verona, Verona, Italy. dds.univr@hotmail.it</nlm:affiliation>
<country xml:lang="fr">Italie</country>
<wicri:regionArea>Department of Morphological and Biomedical Sciences, Section of Dentistry and Maxillofacial Surgery, University of Verona, Verona</wicri:regionArea>
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<name sortKey="Trevisiol, Lorenzo" sort="Trevisiol, Lorenzo" uniqKey="Trevisiol L" first="Lorenzo" last="Trevisiol">Lorenzo Trevisiol</name>
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<name sortKey="D Agostino, Antonio" sort="D Agostino, Antonio" uniqKey="D Agostino A" first="Antonio" last="D'Agostino">Antonio D'Agostino</name>
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<name sortKey="Cucchi, Alessandro" sort="Cucchi, Alessandro" uniqKey="Cucchi A" first="Alessandro" last="Cucchi">Alessandro Cucchi</name>
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<name sortKey="De Gemmis, Antonio" sort="De Gemmis, Antonio" uniqKey="De Gemmis A" first="Antonio" last="De Gemmis">Antonio De Gemmis</name>
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<name sortKey="Nocini, Pier Francesco" sort="Nocini, Pier Francesco" uniqKey="Nocini P" first="Pier Francesco" last="Nocini">Pier Francesco Nocini</name>
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<title xml:lang="en">Guided bone regeneration with autogenous block grafts applied to Le Fort I osteotomy for treatment of severely resorbed maxillae: a 4- to 6-year prospective study.</title>
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<name sortKey="Trevisiol, Lorenzo" sort="Trevisiol, Lorenzo" uniqKey="Trevisiol L" first="Lorenzo" last="Trevisiol">Lorenzo Trevisiol</name>
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<term>Adult</term>
<term>Aged</term>
<term>Aged, 80 and over</term>
<term>Alveolar Bone Loss (diagnostic imaging)</term>
<term>Alveolar Bone Loss (surgery)</term>
<term>Alveolar Ridge Augmentation (methods)</term>
<term>Bone Transplantation (methods)</term>
<term>Denture, Complete</term>
<term>Female</term>
<term>Guided Tissue Regeneration</term>
<term>Humans</term>
<term>Jaw, Edentulous (diagnostic imaging)</term>
<term>Jaw, Edentulous (surgery)</term>
<term>Male</term>
<term>Maxillary Diseases (diagnostic imaging)</term>
<term>Maxillary Diseases (surgery)</term>
<term>Middle Aged</term>
<term>Oral Surgical Procedures, Preprosthetic (methods)</term>
<term>Osteotomy, Le Fort</term>
<term>Prospective Studies</term>
<term>Radiography</term>
<term>Treatment Outcome</term>
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<term>Adulte</term>
<term>Adulte d'âge moyen</term>
<term>Femelle</term>
<term>Humains</term>
<term>Maladies du maxillaire supérieur ()</term>
<term>Maladies du maxillaire supérieur (imagerie diagnostique)</term>
<term>Mâchoire édentée ()</term>
<term>Mâchoire édentée (imagerie diagnostique)</term>
<term>Mâle</term>
<term>Ostéotomie de Le Fort</term>
<term>Procédures de chirurgie préprothétique en odontologie ()</term>
<term>Prothèse dentaire complète</term>
<term>Radiographie</term>
<term>Reconstruction de crête alvéolaire ()</term>
<term>Régénération tissulaire guidée</term>
<term>Résorption alvéolaire ()</term>
<term>Résorption alvéolaire (imagerie diagnostique)</term>
<term>Résultat thérapeutique</term>
<term>Sujet âgé</term>
<term>Sujet âgé de 80 ans ou plus</term>
<term>Transplantation osseuse ()</term>
<term>Études prospectives</term>
</keywords>
<keywords scheme="MESH" qualifier="diagnostic imaging" xml:lang="en">
<term>Alveolar Bone Loss</term>
<term>Jaw, Edentulous</term>
<term>Maxillary Diseases</term>
</keywords>
<keywords scheme="MESH" qualifier="imagerie diagnostique" xml:lang="fr">
<term>Maladies du maxillaire supérieur</term>
<term>Mâchoire édentée</term>
<term>Résorption alvéolaire</term>
</keywords>
<keywords scheme="MESH" qualifier="methods" xml:lang="en">
<term>Alveolar Ridge Augmentation</term>
<term>Bone Transplantation</term>
<term>Oral Surgical Procedures, Preprosthetic</term>
</keywords>
<keywords scheme="MESH" qualifier="surgery" xml:lang="en">
<term>Alveolar Bone Loss</term>
<term>Jaw, Edentulous</term>
<term>Maxillary Diseases</term>
</keywords>
<keywords scheme="MESH" xml:lang="en">
<term>Adult</term>
<term>Aged</term>
<term>Aged, 80 and over</term>
<term>Denture, Complete</term>
<term>Female</term>
<term>Guided Tissue Regeneration</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Osteotomy, Le Fort</term>
<term>Prospective Studies</term>
<term>Radiography</term>
<term>Treatment Outcome</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr">
<term>Adulte</term>
<term>Adulte d'âge moyen</term>
<term>Femelle</term>
<term>Humains</term>
<term>Maladies du maxillaire supérieur</term>
<term>Mâchoire édentée</term>
<term>Mâle</term>
<term>Ostéotomie de Le Fort</term>
<term>Procédures de chirurgie préprothétique en odontologie</term>
<term>Prothèse dentaire complète</term>
<term>Radiographie</term>
<term>Reconstruction de crête alvéolaire</term>
<term>Régénération tissulaire guidée</term>
<term>Résorption alvéolaire</term>
<term>Résultat thérapeutique</term>
<term>Sujet âgé</term>
<term>Sujet âgé de 80 ans ou plus</term>
<term>Transplantation osseuse</term>
<term>Études prospectives</term>
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<front>
<div type="abstract" xml:lang="en">Edentulism causes progressive bone resorption of the maxillae, which can lead to altered maxillo-mandibular relationships. The aim of the study was to evaluate the applicability of guided bone regeneration (GBR) to Le Fort I osteotomies with interpositional bone grafts for treatment of patients with severe maxillary atrophy.</div>
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<DateCompleted>
<Year>2012</Year>
<Month>05</Month>
<Day>31</Day>
</DateCompleted>
<DateRevised>
<Year>2016</Year>
<Month>11</Month>
<Day>25</Day>
</DateRevised>
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<ISSN IssnType="Electronic">1600-0501</ISSN>
<JournalIssue CitedMedium="Internet">
<Volume>23</Volume>
<Issue>1</Issue>
<PubDate>
<Year>2012</Year>
<Month>Jan</Month>
</PubDate>
</JournalIssue>
<Title>Clinical oral implants research</Title>
<ISOAbbreviation>Clin Oral Implants Res</ISOAbbreviation>
</Journal>
<ArticleTitle>Guided bone regeneration with autogenous block grafts applied to Le Fort I osteotomy for treatment of severely resorbed maxillae: a 4- to 6-year prospective study.</ArticleTitle>
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<AbstractText Label="INTRODUCTION" NlmCategory="BACKGROUND">Edentulism causes progressive bone resorption of the maxillae, which can lead to altered maxillo-mandibular relationships. The aim of the study was to evaluate the applicability of guided bone regeneration (GBR) to Le Fort I osteotomies with interpositional bone grafts for treatment of patients with severe maxillary atrophy.</AbstractText>
<AbstractText Label="MATERIALS AND METHODS" NlmCategory="METHODS">Twenty consecutive patients characterized by severely atrophic maxillae were treated from January 2003 to January 2006 in order to resolve maxillary edentulism. All patients underwent pre-prosthetic surgery, including a Le Fort I osteotomy associated with autologous interpositional bone grafts to move the alveolar arch forward and to resolve the maxillary atrophy. Barrier membranes were also used to cover the bone grafts and the osteotomy line, favoring the healing process according to GBR principles. Maxilla advancement and alveolar crest augmentation were measured to assess the degree of reconstruction. A total of 154 implants were inserted in reconstructed maxillae 4 months after surgery and were restored with fixed full-arch dentures after another 4 months. Surgical and prosthetic complications were recorded and previously established implant success criteria were used to assess the success of this treatment protocol.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">The outcome of pre-prosthetic surgery and implant-supported rehabilitation was prospectively evaluated every year. All Le Fort I osteotomies were successfully carried out, with a mean maxilla advancement of 4.2 cm (range: 3.1-5 cm), which appeared to be stable during the follow-up. After a mean follow-up of 66.4 ± 18.4 months, only four implants failed according to the success criteria, yielding a cumulative success rate of 95.8%.</AbstractText>
<AbstractText Label="DISCUSSION AND CONCLUSIONS" NlmCategory="CONCLUSIONS">Le Fort I osteotomies with the use of barrier membranes to cover the interpositional bone grafts can be a predictable treatment for edentulous patients with severely resorbed maxillae. The study data suggest that this approach makes it possible to compensate for both sagittal and vertical discrepancies due to maxilla atrophy, with a minimum resorption of advanced maxillae and grafted bone. A GBR-based protocol seems to lead to high implant success rates, although further randomized controlled studies are needed to demonstrate the usefulness and advantageousness of GBR.</AbstractText>
<CopyrightInformation>© 2011 John Wiley & Sons A/S.</CopyrightInformation>
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<ForeName>Daniele</ForeName>
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<Affiliation>Department of Morphological and Biomedical Sciences, Section of Dentistry and Maxillofacial Surgery, University of Verona, Verona, Italy. dds.univr@hotmail.it</Affiliation>
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<Language>eng</Language>
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<Year>2011</Year>
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<Country>Denmark</Country>
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