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Horizontal ridge augmentation of the atrophic anterior maxilla using rhBMP-2/ACS or autogenous bone grafts: a proof-of-concept randomized clinical trial.

Identifieur interne : 000B23 ( PubMed/Curation ); précédent : 000B22; suivant : 000B24

Horizontal ridge augmentation of the atrophic anterior maxilla using rhBMP-2/ACS or autogenous bone grafts: a proof-of-concept randomized clinical trial.

Auteurs : Rubens Moreno De Freitas [Brésil] ; Cristiano Susin ; Rubens Spin-Neto ; Claudio Marcantonio ; Ulf M E. Wikesjö ; Luís Antônio Violin Dias Pereira ; Elcio Marcantonio

Source :

RBID : pubmed:23998375

Descripteurs français

English descriptors

Abstract

To compare the effect of recombinant human bone morphogenetic protein-2 (rhBMP-2) in an absorbable collagen sponge carrier (ACS) with autogenous bone graft for augmentation of the edentulous atrophic anterior maxilla.

DOI: 10.1111/jcpe.12148
PubMed: 23998375

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Links to Exploration step

pubmed:23998375

Le document en format XML

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<term>Collagène</term>
<term>Facteur de croissance transformant bêta (usage thérapeutique)</term>
<term>Femelle</term>
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<term>Humains</term>
<term>Implant résorbable</term>
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<term>Matériaux biocompatibles ()</term>
<term>Maxillaire ()</term>
<term>Maxillaire (imagerie diagnostique)</term>
<term>Mâchoire partiellement édentée ()</term>
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<term>Protéines recombinantes (usage thérapeutique)</term>
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<term>Maxillaire</term>
<term>Mâchoire partiellement édentée</term>
<term>Processus alvéolaire</term>
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<term>Alveolar Ridge Augmentation</term>
<term>Bone Transplantation</term>
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<term>Adult</term>
<term>Atrophy</term>
<term>Collagen</term>
<term>Dental Implants</term>
<term>Drug Carriers</term>
<term>Female</term>
<term>Follow-Up Studies</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
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<term>Atrophie</term>
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<front>
<div type="abstract" xml:lang="en">To compare the effect of recombinant human bone morphogenetic protein-2 (rhBMP-2) in an absorbable collagen sponge carrier (ACS) with autogenous bone graft for augmentation of the edentulous atrophic anterior maxilla.</div>
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<Month>07</Month>
<Day>03</Day>
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<Year>2016</Year>
<Month>11</Month>
<Day>25</Day>
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<ISSN IssnType="Electronic">1600-051X</ISSN>
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<Volume>40</Volume>
<Issue>10</Issue>
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<Year>2013</Year>
<Month>Oct</Month>
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<Title>Journal of clinical periodontology</Title>
<ISOAbbreviation>J. Clin. Periodontol.</ISOAbbreviation>
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<ArticleTitle>Horizontal ridge augmentation of the atrophic anterior maxilla using rhBMP-2/ACS or autogenous bone grafts: a proof-of-concept randomized clinical trial.</ArticleTitle>
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<AbstractText Label="AIM" NlmCategory="OBJECTIVE">To compare the effect of recombinant human bone morphogenetic protein-2 (rhBMP-2) in an absorbable collagen sponge carrier (ACS) with autogenous bone graft for augmentation of the edentulous atrophic anterior maxilla.</AbstractText>
<AbstractText Label="METHODS" NlmCategory="METHODS">Twenty-four subjects were enrolled in a randomized, controlled, parallel-group, open-label clinical trial. Subjects either received rhBMP-2/ACS (1.5 mg/ml) or particulated autogenous bone harvested from the mandibular retromolar region. A titanium-mesh was used to provide space and wound stability. A guide was used to standardize clinical recordings using an analogue caliper. Alveolar ridge width was also assessed using cone-beam computed tomography.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">rhBMP-2/ACS yielded significantly greater radiographic horizontal bone gain compared with autogenous bone graft at immediate subcrestal levels (1.5 ± 0.7 versus 0.5 ± 0.9 mm; p = 0.01); non-significant differences were observed at mid- (2.9 ± 0.8 versus 2.9 ± 0.9 mm; p = 0.98) and apical (1.7 ± 0.9 versus 1.8 ± 1.1 mm; p = 0.85) crestal levels. No significant differences in clinical horizontal bone gain were observed at 6 months between rhBMP-2/ACS and autogenous bone graft (3.2 ± 0.9 mm versus 3.7 ± 1.4 mm; p = 0.31). Sixty-two implants were placed after 6 month of healing with no significant differences between groups for number of implants, implant size, primary stability and survival.</AbstractText>
<AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">rhBMP-2/ACS appears a realistic alternative for augmentation of the edentulous atrophic anterior maxilla.</AbstractText>
<CopyrightInformation>© 2013 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.</CopyrightInformation>
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   |area=    EdenteV2
   |flux=    PubMed
   |étape=   Curation
   |type=    RBID
   |clé=     pubmed:23998375
   |texte=   Horizontal ridge augmentation of the atrophic anterior maxilla using rhBMP-2/ACS or autogenous bone grafts: a proof-of-concept randomized clinical trial.
}}

Pour générer des pages wiki

HfdIndexSelect -h $EXPLOR_AREA/Data/PubMed/Curation/RBID.i   -Sk "pubmed:23998375" \
       | HfdSelect -Kh $EXPLOR_AREA/Data/PubMed/Curation/biblio.hfd   \
       | NlmPubMed2Wicri -a EdenteV2 

Wicri

This area was generated with Dilib version V0.6.32.
Data generation: Thu Nov 30 15:26:48 2017. Site generation: Tue Mar 8 16:36:20 2022